Spots Global Cancer Trial Database for Multi-Omic Assessment of Squamous Cell Cancers Receiving Systemic Therapy
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Trial Identification
Brief Title: Multi-Omic Assessment of Squamous Cell Cancers Receiving Systemic Therapy
Official Title: Multi-Omic Assessment of Squamous Cell Cancers Receiving Systemic Therapy
Study ID: NCT03712566
Interventions
Study Description
Brief Summary: This is prospective research study which will include patients with recurrent or metastatic squamous cell carcinoma of the head and neck, esophagus and anal canal starting on first-line platinum based chemotherapy or any line of immunotherapy treatment.This study aims to characterize the dynamic changes in genomic, epigenetic, immune profiling and imaging data during treatment with systemic therapy. Patients will have archived tumor samples requested as well as blood samples collected at up to four time points to analyze these changes. Imaging data will be derived from patients' routine CT scans before and after treatment.
Detailed Description:
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Princess Margaret Cancer Centre, Toronto, Ontario, Canada
Contact Details
Name: Elena Elimova, MD
Affiliation: Princess Margaret Cancer Centre
Role: PRINCIPAL_INVESTIGATOR
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