Spots Global Cancer Trial Database for Liquid Biopsy Evaluation and Repository Development at Princess Margaret
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Trial Identification
Brief Title: Liquid Biopsy Evaluation and Repository Development at Princess Margaret
Official Title: Liquid Biopsy Evaluation and Repository Development at Princess Margaret
Study ID: NCT03702309
Interventions
Study Description
Brief Summary: The objective of this protocol is to develop an institution-wide liquid biopsy protocol that will establish a common process for collecting blood and corresponding archived tumor specimens for future research studies at the University Health Network's Princess Margaret Cancer Centre. Circulating cell-free nucleic acids (cfNA), including cell-free DNA (cfDNA) and cell-free RNA (cfRNA), are non-invasive, real-time biomarkers that can provide diagnostic and prognostic information before cancer diagnosis, during cancer treatment, and at disease progression. Cancer research scientists and clinicians at the Princess Margaret are interested in incorporating the collection of peripheral blood samples ("liquid biopsies") into research protocols as a means of non-invasively assessing tumor progression and response to treatment at multiple time points during a patient's course of disease.
Detailed Description:
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: Yes
Locations
Princess Margaret Cancer Centre, Toronto, Ontario, Canada
Contact Details
Name: Lillian Siu, MD
Affiliation: Princess Margaret Cancer Centre
Role: PRINCIPAL_INVESTIGATOR
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