Spots Global Cancer Trial Database for cryoablation
Every month we try and update this database with for cryoablation cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.
The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
| Study title | NCT ID | Conditions | Interventions | Eligibility | Organization | Link |
|---|---|---|---|---|---|---|
| Cryoablation Combined With Camrelizumab and Apatinib in Advanced Hepatocellular Carcinoma | NCT04724226 | Hepatocellular ... | Camrelizumab; A... | 18 Years - 70 Years | Sun Yat-sen University | |
| Cryoablation vs Lumpectomy in T1 Breast Cancers | NCT05505643 | Breast Cancer Breast Neoplasm | Endocare SlimLi... Lumpectomy | 50 Years - | Washington University School of Medicine | |
| To Detect Cryoimmunologic Response Induced by Early Breast Cancer Ultrasound-guided Cryoablation (ICE-study) | NCT05727813 | Cancer, Treatme... Tumor of Breast Systemic Inflam... Stage I Breast ... | cryoablation | 18 Years - | University of Roma La Sapienza | |
| Safety and Efficacy of Cryoablation for Metastatic Lung Tumors | NCT01307501 | Metastatic Lung... | Cryoablation | 18 Years - | Boston Scientific Corporation | |
| Image-guided Cryoablation of Head, Neck and Spine Tumors | NCT02085941 | Head and Neck N... Malignant Neopl... | Cryoablation Biopsy | 18 Years - | Dana-Farber Cancer Institute | |
| Cryoablation for Advanced Bone and Soft Tissue Tumors | NCT05615545 | Sarcoma Cryoablation | Cryoablation | - | Henan Cancer Hospital | |
| Cryoablation Combined With Sintilimab Plus Lenvatinib in 1L Treatment of Advanced ICC (CASTLE-ICC-Chemo-free) | NCT05835245 | Advanced Intrah... | Cryoablation Sintilimab Lenvatinib | 18 Years - | Fudan University | |
| Cryoablation Combined With Tislelizumab Plus Lenvatinib in 1L Treatment of Advanced HCC (CASTLE-10) | NCT05897268 | Hepatocellular ... | Cryoablation Tislelizumab Lenvatinib | 18 Years - | Fudan University | |
| Safety and Efficacy of Cryoablation Combined With Radiation Therapy for the Palliation of Painful Bone Metastases | NCT01461252 | Pain Neoplasm Metast... | Cryoablation Radiation | 18 Years - | Boston Scientific Corporation | |
| Cryoablation Combined With Cardonilizumab and Bevacizumab in Hepatocellular Carcinoma With Pulmonary Metastases | NCT06265350 | Hepatocellular ... Liver Cancer St... Pulmonary Metas... Cadonilimab Bevacizumab Cryoablation | Cadonilimab Bevacizumab Cryoablation | 18 Years - 75 Years | Sun Yat-sen University | |
| Percutaneous Cryoablation Versus Partial Nephrectomy for T1b Renal Tumor | NCT04506671 | Renal Tumor | Renal biopsy Cryoablation Partial nephrec... | 18 Years - | I.M. Sechenov First Moscow State Medical University | |
| COOL-IT-PRO: Cryoablation of Breast Cancer in Non-surgical Patients | NCT05972343 | Breast Cancer Cancer of the B... | Cryoablation | 18 Years - | Washington University School of Medicine | |
| Tracking Renal Tumors After Cryoablation Evaluation | NCT01117779 | Kidney Neoplasm... | Cryoablation | 18 Years - | Boston Scientific Corporation | |
| Cryoablation as a Minimally Invasive Alternative to Surgery for Managing Ductal Carcinoma In Situ | NCT05218044 | Ductal Carcinom... | Cryoablation | 18 Years - | Glendale Adventist Medical Center d/b/a Adventist Health Glendale | |
| Radiomics Compared With Conventional Response Criteria for Predicting Progression of Desmoid Tumor After Cryoablation | NCT06224283 | Desmoid | Cryoablation | - | Istituto Ortopedico Rizzoli | |
| Cryoablation and RFA of Benign Thyroid Nodules: Pilot Study | NCT06014229 | Benign Thyroid ... | cryoablation radiofrequency ... | 18 Years - | University of Sao Paulo General Hospital | |
| Comparative Effectiveness of Cryoablation Versus Steroid and Lidocaine Alone for Treatment of Morton's Neuroma | NCT05501262 | Morton Neuroma | Cryoablation Nerve block | 18 Years - 105 Years | Oregon Health and Science University | |
| AlloStim® In-Situ Vaccine in Pre-Treated Metastatic Colorectal Cancer | NCT01741038 | Metastatic Colo... | AlloStim® cryoablation Physician's Cho... | 18 Years - | Immunovative Therapies, Ltd. | |
| Phase I Clinical Trial of Cryoimmunotherapy Against Prostate Cancer | NCT02423928 | Prostate Cancer | Dendritic cell ... Cyclophosphamid... ipilimumab | 18 Years - | Alden Cancer Therapy II | |
| Robot-assisted Surgical Resection vs. Cryoablation of Localised Renal Cancer | NCT03390413 | Renal Cancer | Robot Cryoablation | 18 Years - 99 Years | Aarhus University Hospital | |
| Cryoablation for Advanced and Refractory Desmoid Tumors | NCT06113094 | Desmoid Tumors | 18 Years - | University Hospital, Strasbourg, France | ||
| A Pilot Study of Combined Immune Checkpoint Inhibition in Combination With Ablative Therapies in Subjects With Hepatocellular Carcinoma (HCC) or Biliary Tract Carcinomas (BTC) | NCT02821754 | Biliary Tract N... Liver Cancer Hepatocellular ... Cholangiocarcin... Bile Duct Cance... | Durvalumab Tremelimumab Trans-arterial ... Radiofrequency ... Cryoablation | 18 Years - | National Institutes of Health Clinical Center (CC) | |
| Focal US-guided Cryo-ablation Using DynaCAD / UroNAV Preplanning / Guidance of Intermediate Risk Prostate Cancer | NCT04656678 | Prostate Cancer Prostate Diseas... | Cryo-ablation U... | 45 Years - | Northwell Health | |
| Cryoablation+Ipilimumab+Nivolumab in Melanoma | NCT05779423 | Metastatic Mela... Skin Cancer | Ipilimumab Nivolumab Cryoablation | 18 Years - | Massachusetts General Hospital | |
| Experimental Therapeutic Cancer Vaccine Created In-situ in Patients With Stage II-Stage IV Cancer | NCT01065441 | Solid Tumors St... Breast Cancer Colorectal Canc... Prostate Cancer Melanoma Ovarian Cancer Sarcoma Non-small Cell ... | AlloStim Cryoablation AlloStim AlloStim AlloStim AlloStim AlloStim | 18 Years - | Immunovative Therapies, Ltd. | |
| Cryoablation Combined With Cardonilizumab and Bevacizumab in Hepatocellular Carcinoma With Pulmonary Metastases | NCT06265350 | Hepatocellular ... Liver Cancer St... Pulmonary Metas... Cadonilimab Bevacizumab Cryoablation | Cadonilimab Bevacizumab Cryoablation | 18 Years - 75 Years | Sun Yat-sen University | |
| Percutaneous Cryoablation of Low-risk Early Breast Cancer | NCT06300125 | Breast Cancer | Cryoablation | 50 Years - | European Institute of Oncology | |
| A Study of Pembrolizumab and Cryoablation in People With Breast Cancer | NCT06246968 | Metastatic Brea... Breast Cancer Breast Cancer S... Triple Negative... Triple Negative... Metastatic Trip... Locally Advance... Locally Advance... | Pembrolizumab Cryoablation | 18 Years - | Memorial Sloan Kettering Cancer Center | |
| Compare Ultrasound Assisted Cold Therapy and Lidocaine Injection to Treat Morton's Neuroma | NCT02838758 | Intermetatarsal... | Cryoablation Lidocaine Saline | 18 Years - 80 Years | Icahn School of Medicine at Mount Sinai | |
| Cryoablation Combined With Sintilimab Plus Lenvatinib in Patients With Immune Checkpoint Inhibitor Previously Treated Advanced Biliary Tract Cancer （CASTLE-08） | NCT05781074 | Advanced Biliar... | Sintilimab Lenvatinib Cryoablation | 18 Years - | Fudan University | |
| Percutaneous Renal Tumor Cryoablation Followed by Biopsy | NCT01012427 | Renal Cancer | percutaneous cr... | 21 Years - | Memorial Sloan Kettering Cancer Center | |
| COOL-IT-PRO: Cryoablation of Breast Cancer in Non-surgical Patients | NCT05972343 | Breast Cancer Cancer of the B... | Cryoablation | 18 Years - | Washington University School of Medicine | |
| Focal Therapy for Localized Prostate Cancer | NCT06270043 | Prostate Cancer | Focal Therapy | 18 Years - | University of California, San Diego | |
| Safety and Efficacy of Cryoablation for the Palliation of Painful Bone Metastases | NCT01461265 | Pain Neoplasm Metast... | Cryoablation | 18 Years - | Boston Scientific Corporation | |
| Cryoablation in Combination (or Not) With Pembrolizumab and Pemetrexed-carboplatin in 1st-line Treatment for Patients With Metastatic Lung Adenocarcinoma | NCT04339218 | Lung Adenocarci... Cryotherapy Eff... | Cryoablation Pembrolizumab Pemetrexed Carboplatin | 18 Years - | Institut Bergonié | |
| Study of Core Needle Biopsy and Cryoablation of an Enlarging Tumor in Patients With Metastatic Lung Cancer and Metastatic Melanoma Receiving Post-progression Immune Checkpoint Inhibitor Therapy | NCT03290677 | Lung Cancer | Cryoablation Biopsy | 18 Years - | Massachusetts General Hospital | |
| Cryoablation Versus Medical Therapy in Desmoid Tumors Progressing After Watchful Waiting | NCT06081400 | Desmoid Tumor | Cryoablation Chemotherapy dr... | 13 Years - | University Hospital, Strasbourg, France | |
| Cryoablation Combined With Tislelizumab Plus Lenvatinib In Previously Treated Gastric Cancer Liver Metastasis (CASTLE-09) | NCT05893056 | Gastric Cancer ... | Cryoablation Tislelizumab Lenvatinib | 18 Years - | Fudan University | |
| Cryoablation vs Lumpectomy in T1 Breast Cancers | NCT05505643 | Breast Cancer Breast Neoplasm | Endocare SlimLi... Lumpectomy | 50 Years - | Washington University School of Medicine | |
| Multicenter Study of Cryoablation for Palliation of Painful Bone Metastases | NCT02511678 | Pain Neoplasm Metast... Bone Metastasis... | Cryoablation | 18 Years - | Boston Scientific Corporation | |
| Grouping Immune-modulation With Cryoablation (LOGIC) for Breast Cancers | NCT05806385 | Triple Negative... | Cryoablation Cryoablation co... | 18 Years - 90 Years | Texas Tech University Health Sciences Center | |
| Anti-Tumor Immunity Induced by Cryoablation of Invasive Breast Cancers | NCT01856036 | Breast Cancer | Cryoablation | 18 Years - | Saint John's Cancer Institute | |
| Cryoablation Combined With Tislelizumab Plus Lenvatinib in 1L Treatment of Advanced HCC (CASTLE-10) | NCT05897268 | Hepatocellular ... | Cryoablation Tislelizumab Lenvatinib | 18 Years - | Fudan University | |
| TURBt With Adjuvant Cryoablation to Treat Bladder Cancer | NCT02760953 | Urinary Bladder... | Cryoablation Epirubicin | 18 Years - 85 Years | Huashan Hospital | |
| Cryoablation as a Minimally Invasive Alternative to Surgery for Managing Ductal Carcinoma In Situ | NCT05218044 | Ductal Carcinom... | Cryoablation | 18 Years - | Glendale Adventist Medical Center d/b/a Adventist Health Glendale | |
| Evaluation of Percutaneous Treatment by Cryoablation of Unifocal Invasive Breast Carcinoma in Menopausal Women With Indication of Lumpectomy | NCT02576106 | Carcinoma, Duct... Menopausal | Cryoablation | 55 Years - | Centre Leon Berard | |
| Cryoablation of Small Breast Tumors in Early Stage Breast Cancer | NCT01992250 | Breast Cancer | Visica 2 Treatm... | 50 Years - | Sanarus Technologies, Inc. | |
| Toripalimab Combined With Cryoablation for First-line Oligo-progression in Driver-negative Advanced NSCLC | NCT06127303 | Non-small Cell ... | Toripalimab Cryoablation | 18 Years - 75 Years | Shanghai Chest Hospital | |
| Endocrine Therapy With or Without Cryoablation for Stage IV Prostate Cancer | NCT02615223 | Stage IV Prosta... | cryoablation Bicalutamide luteinizing-hor... | 18 Years - 80 Years | Tianjin Medical University Cancer Institute and Hospital | |
| Cryoablation, Radiofrequency Ablation, or Microwave Ablation in Treating Patients With Metastatic Sarcoma Stable on Chemotherapy | NCT01986829 | Osteosarcoma Sarcoma | Microwave ablat... Cryoablation Radiofrequency ... BPI-Short form FACT-G7 | 18 Years - | Washington University School of Medicine | |
| A Randomized Trial of External Beam Radiotherapy Versus Cryoablation in Patients With Localized Prostate Cancer | NCT00489060 | Prostate Cancer | Cryoablation an... | - | University of Calgary | |
| Cryoablation of Bone Metastases From Endocrine Tumors | NCT03986593 | Neoplasm Metast... Thyroid Neoplas... Pheochromocytom... Adrenal Neoplas... Neuroendocrine ... Bone Metastases | cryoablation | 18 Years - | Instituto do Cancer do Estado de São Paulo | |
| Valuation of the Safety and Efficacy of Combination of Cryoablation and Dendric Cell/Cytokine-induced Killers Cells Treatment for Advanced Liver Cancers | NCT05622825 | Advanced Liver ... | DC-CIK | 20 Years - 80 Years | National Taiwan University Hospital | |
| Focal Therapy for Localized Prostate Cancer | NCT06270043 | Prostate Cancer | Focal Therapy | 18 Years - | University of California, San Diego | |
| Cryoablation Combined With Tislelizumab Plus Lenvatinib In Previously Treated Solid Tumors (CASTLE-11) | NCT06032845 | Solid Tumor, Ad... | Tislelizumab Lenvatinib Cryoablation | 18 Years - | Fudan University | |
| Thermal Ablation of Cervical Metastases From Thyroid Carcinoma | NCT04522570 | Thyroid Neoplas... Well-Differenti... Medullary Thyro... Lymph Node Meta... | Laser ablation Cryoablation Radiofrequency ... | 18 Years - | Instituto do Cancer do Estado de São Paulo | |
| Cryoablation Combined With Sintilimab Plus Lenvatinib In Previously Treated Unresectable Liver Metastasis From Solid Tumors | NCT05098847 | Liver Metastasi... | Sintilimab Lenvatinib Cryoablation | 18 Years - | Fudan University | |
| Percutaneous Cryoablation of Low-risk Early Breast Cancer | NCT06300125 | Breast Cancer | Cryoablation | 50 Years - | European Institute of Oncology | |
| Valuation of the Safety and Efficacy of Combination of Cryoablation and Dendric Cell/Cytokine-induced Killers Cells Treatment for Advanced Liver Cancers | NCT05622825 | Advanced Liver ... | DC-CIK | 20 Years - 80 Years | National Taiwan University Hospital | |
| Comparative Effectiveness of Cryoablation Versus Steroid and Lidocaine Alone for Treatment of Morton's Neuroma | NCT05501262 | Morton Neuroma | Cryoablation Nerve block | 18 Years - 105 Years | Oregon Health and Science University | |
| Cryoablation Combined With Tislelizumab Plus Lenvatinib in Patients With Melanoma Liver Metastasis | NCT05406466 | Melanoma | Tislelizumab Lenvatinib Cryoablation | 18 Years - | Fudan University | |
| FreezIng bReaST Cancer in Brazil: a Before-after Study | NCT05398497 | Breast Cancer Breast Neoplasm... | Cryoablation | 18 Years - | Hospital do Coracao | |
| Pre-Operative, Single-Dose Ipilimumab and/or Cryoablation in Early Stage/Resectable Breast Cancer | NCT01502592 | Breast Cancer Invasive Adenoc... | Cryoablation Ipilimumab | 18 Years - | Memorial Sloan Kettering Cancer Center | |
| Phase I Clinical Trial of Cryoimmunotherapy Against Prostate Cancer | NCT02423928 | Prostate Cancer | Dendritic cell ... Cyclophosphamid... ipilimumab | 18 Years - | Alden Cancer Therapy II | |
| Standardization of Multi-modal Tumor Ablation Therapy System | NCT03223142 | Liver Neoplasms Ablation Techni... Cryoablation Safety Treatment Outco... Neoplasm Metast... Clinical Trial | Multi-modal Pre... | 18 Years - 70 Years | Shanghai Zhongshan Hospital | |
| Study of Cryoablation and Nirogacestat for Desmoid Tumor | NCT05949099 | Desmoid Tumor | Nirogacestat Cryoablation | 18 Years - | Stanford University | |
| Safety and Efficacy of Cryoablation for Metastatic Lung Tumors | NCT01307501 | Metastatic Lung... | Cryoablation | 18 Years - | Boston Scientific Corporation | |
| Tremelimumab With Chemoembolization or Ablation for Liver Cancer | NCT01853618 | Heptocellular C... Biliary Tract N... Liver Cancer Hepatocellular ... Biliary Cancer | Tremelimumab RFA TACE Cryoablation | 18 Years - 99 Years | National Institutes of Health Clinical Center (CC) | |
| Percutaneous Cryoablation of Central Kidney Tumours With Temporary Renal Artery Occlusion | NCT05461027 | Kidney Cancer | 18 Years - | University Hospital, Strasbourg, France | ||
| Increased Frequency of AlloStim(TM) Dosing in Combination With Cryoablation in Metastatic Breast Cancer Patients | NCT02018419 | Metastatic Brea... | AlloStim Cryoablation | 18 Years - 70 Years | Immunovative Therapies, Ltd. | |
| Evaluation of Percutaneous Treatment by Cryoablation of Unifocal Invasive Breast Carcinoma in Menopausal Women With Indication of Lumpectomy | NCT02576106 | Carcinoma, Duct... Menopausal | Cryoablation | 55 Years - | Centre Leon Berard | |
| Toripalimab Combined With Cryoablation for First-line Oligo-progression in Driver-negative Advanced NSCLC | NCT06127303 | Non-small Cell ... | Toripalimab Cryoablation | 18 Years - 75 Years | Shanghai Chest Hospital | |
| AlloStim® Immunotherapy Dosing Alone or in Combination With Cryoablation in Metastatic Colorectal Cancer | NCT02380443 | Colorectal Canc... | AlloStim Cryoablation | 18 Years - 80 Years | Immunovative Therapies, Ltd. | |
| Safety and Efficacy of Cryoablation for Abdominal Pain Associated With Pancreatic Cancer | NCT01335945 | Pain Pancreatic Canc... | Cryoablation | 18 Years - | Boston Scientific Corporation | |
| Pilot Study to Define the Immune Response Following Cryoablation of Invasive Breast Cancer | NCT03523299 | Invasive Ductal... | Cryoablation | 18 Years - | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | |
| Cryoablation Versus Radiofrequency Ablation for Small Renal Masses | NCT00922948 | Renal Cancers | Cryoablation Radiofrequency ... | 18 Years - 90 Years | St. Joseph's Healthcare Hamilton | |
| AlloStim® Immunotherapy Dosing Alone or in Combination With Cryoablation in Metastatic Colorectal Cancer | NCT02380443 | Colorectal Canc... | AlloStim Cryoablation | 18 Years - 80 Years | Immunovative Therapies, Ltd. | |
| Cryoablation Combined With Sintilimab Plus Lenvatinib in Patients With Immune Checkpoint Inhibitor Previously Treated Advanced Biliary Tract Cancer （CASTLE-08） | NCT05781074 | Advanced Biliar... | Sintilimab Lenvatinib Cryoablation | 18 Years - | Fudan University | |
| Prostate Conformal Cryotherapy | NCT00877682 | Prostate Cancer | Cryoablation | - | M.D. Anderson Cancer Center | |
| Safety and Efficacy of Cryoablation for the Palliation of Painful Bone Metastases | NCT01461265 | Pain Neoplasm Metast... | Cryoablation | 18 Years - | Boston Scientific Corporation |
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