Spots Global Cancer Trial Database for cns
Every month we try and update this database with for cns cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.
The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
| Study title | NCT ID | Conditions | Interventions | Eligibility | Organization | Link |
|---|---|---|---|---|---|---|
| Primary Mediastinal Large B-cell Lymphoma With CNS Involvement | NCT06024694 | Primary Mediast... | 18 Years - 80 Years | IRCCS San Raffaele | ||
| Chemo-immunotherapy Using Ibrutinib Plus Indoximod for Patients With Pediatric Brain Cancer | NCT05106296 | Ependymoma Medulloblastoma Glioblastoma Primary Brain T... | Ibrutinib Indoximod Cyclophosphamid... Etoposide | 12 Years - 25 Years | Augusta University | |
| Retrospective Study of MRI With MULTIHANCE at 0.10 and 0.05 mmol/Kg Dose in CNS Patients | NCT03147989 | Central Nervous... Central Nervous... | MultiHance | 2 Years - | Bracco Diagnostics, Inc | |
| Hypofractionated Stereotactic Radiotherapy With Bevacizumab in the Treatment of Recurrent Malignant Glioma | NCT01392209 | Brain Cancer MALIGNANT GLIOM... Glioblastoma Anaplastic Astr... Anaplastic Olig... Anaplastic Olig... Anaplastic Mixe... Malignant Gliom... | Bevacizumab & S... | 18 Years - | Memorial Sloan Kettering Cancer Center | |
| Stereotactic Radiosurgery (SRS) for Multiple CNS Mets | NCT02567643 | Metastatic Canc... Brain Metastase... | Stereotactic Ra... | - | The Cooper Health System | |
| Standard Dose Bevacizumab Versus Low Dose Bevacizumab Plus Lomustine (CCNU) for Recurrent Glioblastoma Multiforme (GBM) | NCT01067469 | Brain Cancer Glioblastoma | Standard Dose B... Low Dose Bevaci... Lomustine | 18 Years - | M.D. Anderson Cancer Center | |
| Study of 4-Demethyl-4-cholesteryloxycarbonylpenclome (DM-CHOC-PEN) in Patients With Brain Tumors | NCT02038218 | Primary Brain T... Metastatic Mali... | 4-Demethyl-4-ch... | 18 Years - | DEKK-TEC, Inc. | |
| Retrospective Study of MRI With MULTIHANCE at 0.10 and 0.05 mmol/Kg Dose in CNS Patients | NCT03147989 | Central Nervous... Central Nervous... | MultiHance | 2 Years - | Bracco Diagnostics, Inc | |
| Intrathecal Rituximab in Lymphoid Malignancies Involving Central Nervous System | NCT01596127 | Leukemia Lymphoid Malign... Metastatic Mali... | Intrathecal Rit... | 3 Years - | M.D. Anderson Cancer Center | |
| CNS Involvement in Primary Mediastinal Large B-Cell Lymphoma (PMLBCL) | NCT05856708 | Primary Mediast... | DISEASE | 18 Years - | IRCCS San Raffaele | |
| Stereotactic Radiosurgery (SRS) for Multiple CNS Mets | NCT02567643 | Metastatic Canc... Brain Metastase... | Stereotactic Ra... | - | The Cooper Health System | |
| DepoCyt Therapy in Patients With Neoplastic Meningitis From Lymphoma or a Solid Tumor | NCT00029523 | Meningeal Neopl... | Intrathecal (in... Intrathecal met... Intrathecal cyt... | 18 Years - | Pacira Pharmaceuticals, Inc | |
| Chemo-immunotherapy Using Ibrutinib Plus Indoximod for Patients With Pediatric Brain Cancer | NCT05106296 | Ependymoma Medulloblastoma Glioblastoma Primary Brain T... | Ibrutinib Indoximod Cyclophosphamid... Etoposide | 12 Years - 25 Years | Augusta University | |
| The Use of 5-aminolevulinic Acid (ALA) as an Intraoperative Tumor Marker for Resection of Pediatric Central Nervous System (CNS) Tumors | NCT02050243 | Central Nervous... | 5ALA | 3 Years - 18 Years | Tel-Aviv Sourasky Medical Center | |
| Proton Beam Therapy for Chondrosarcoma | NCT00496522 | Chondrosarcoma | Proton Beam The... | - | M.D. Anderson Cancer Center | |
| TPI 287 in Patients With Recurrent Glioblastoma Multiforme | NCT01113463 | Brain Cancer | TPI 287 | 18 Years - | M.D. Anderson Cancer Center | |
| DNX-2401 (Formerly Known as Delta-24-RGD-4C) for Recurrent Malignant Gliomas | NCT00805376 | Brain Cancer Central Nervous... | DNX-2401 Tumor Removal | 18 Years - | DNAtrix, Inc. | |
| Primary Mediastinal Large B-cell Lymphoma With CNS Involvement | NCT06024694 | Primary Mediast... | 18 Years - 80 Years | IRCCS San Raffaele | ||
| Pilot Study of Model Based Iterative Reconstruction Using 64-Slice | NCT01431378 | Posterior Fossa... Lung Cancer Flank Pain Urolithiasis Focal Hepatic N... | 30 Years - | GE Healthcare | ||
| Retrospective Study of MRI With MULTIHANCE at 0.10 and 0.05 mmol/Kg Dose in CNS Patients | NCT03147989 | Central Nervous... Central Nervous... | MultiHance | 2 Years - | Bracco Diagnostics, Inc | |
| Proton Beam Therapy for Chondrosarcoma | NCT00496522 | Chondrosarcoma | Proton Beam The... | - | M.D. Anderson Cancer Center | |
| CNS Penetration, PK and PD of Preoperative CC-90010 in Progressive/Recurrent Diffuse Astrocytoma, Anaplastic Astrocytoma and Glioblastoma | NCT04047303 | Astrocytoma Glioblastoma | CC-90010 | 18 Years - | Celgene | |
| A Pilot Study of Bevacizumab for Neoplastic Meningitis | NCT00924820 | Neoplastic Meni... | Bevacizumab | 18 Years - | M.D. Anderson Cancer Center | |
| Treatment of Brain Metastases From Breast Cancer With Eribulin Mesylate | NCT02581839 | Metastatic Brea... Brain Metastase... | Eribulin Mesyla... MRI Pre-Medication:... Pre-Medication:... | 18 Years - | Case Comprehensive Cancer Center | |
| DNX-2401 With Interferon Gamma (IFN-γ) for Recurrent Glioblastoma or Gliosarcoma Brain Tumors | NCT02197169 | Glioblastoma or... | Single intratum... Interferon-gamm... | 18 Years - | DNAtrix, Inc. | |
| Humanized 3F8 Monoclonal Antibody (Hu3F8) in Patients With High-Risk Neuroblastoma and GD2-Positive Tumors | NCT01419834 | Neuroblastoma | Humanized 3F8 M... | 2 Years - | Memorial Sloan Kettering Cancer Center | |
| Study to Evaluate Safety, Tolerability, and Optimal Dose of Candidate GBM Vaccine VBI-1901 in Recurrent GBM Subjects | NCT03382977 | Glioblastoma Mu... | VBI-1901 Carmustine Lomustine | 18 Years - | VBI Vaccines Inc. | |
| The Use of 5-aminolevulinic Acid (ALA) as an Intraoperative Tumor Marker for Resection of Pediatric Central Nervous System (CNS) Tumors | NCT02050243 | Central Nervous... | 5ALA | 3 Years - 18 Years | Tel-Aviv Sourasky Medical Center | |
| Stereotactic Radiosurgery (SRS) for Multiple CNS Mets | NCT02567643 | Metastatic Canc... Brain Metastase... | Stereotactic Ra... | - | The Cooper Health System | |
| Study of 4-Demethyl-4-cholesteryloxycarbonylpenclome (DM-CHOC-PEN) in Patients With Brain Tumors | NCT02038218 | Primary Brain T... Metastatic Mali... | 4-Demethyl-4-ch... | 18 Years - | DEKK-TEC, Inc. | |
| Standard Dose Bevacizumab Versus Low Dose Bevacizumab Plus Lomustine (CCNU) for Recurrent Glioblastoma Multiforme (GBM) | NCT01067469 | Brain Cancer Glioblastoma | Standard Dose B... Low Dose Bevaci... Lomustine | 18 Years - | M.D. Anderson Cancer Center | |
| Imaging Brain Tumors With FACBC and Methionine | NCT00597246 | Brain Cancer CNS Cancer | FACBC, Methioni... PET Scan | - | Memorial Sloan Kettering Cancer Center | |
| Imaging Brain Tumors With FACBC and Methionine | NCT00597246 | Brain Cancer CNS Cancer | FACBC, Methioni... PET Scan | - | Memorial Sloan Kettering Cancer Center | |
| Treatment of Brain Metastases From Breast Cancer With Eribulin Mesylate | NCT02581839 | Metastatic Brea... Brain Metastase... | Eribulin Mesyla... MRI Pre-Medication:... Pre-Medication:... | 18 Years - | Case Comprehensive Cancer Center | |
| Standard Dose Bevacizumab Versus Low Dose Bevacizumab Plus Lomustine (CCNU) for Recurrent Glioblastoma Multiforme (GBM) | NCT01067469 | Brain Cancer Glioblastoma | Standard Dose B... Low Dose Bevaci... Lomustine | 18 Years - | M.D. Anderson Cancer Center | |
| Study of Peptide Vaccination With Tumor Associated Antigens Mixed With Montanide in Patients With CNS Tumors | NCT00935545 | Tumors, Central... | Montanide | - 21 Years | NYU Langone Health | |
| Evaluation of Safety and Efficacy of ProHance in Pediatric Patients <2yrs | NCT03750188 | Central Nervous... Central Nervous... | ProHance | 1 Day - 2 Years | Bracco Diagnostics, Inc | |
| 18-F-Fluoroacetate as PET Imaging Agent | NCT01320787 | Brain Cancer Breast Cancer Prostate Cancer | 18F-fluoroaceta... | 18 Years - | M.D. Anderson Cancer Center | |
| Trial of Anti-PD-1 Immunotherapy and Stereotactic Radiation in Patients With Recurrent Glioblastoma | NCT04977375 | Glioblastoma Mu... | Pembrolizumab Stereotactic Ra... Surgical Resect... | 18 Years - | Cedars-Sinai Medical Center | |
| Brain Stem Gliomas Treated With Adoptive Cellular Therapy During Focal Radiotherapy Recovery Alone or With Dose-intensified Temozolomide (Phase I) | NCT03396575 | Diffuse Intrins... Brain Stem Glio... | TTRNA-DC vaccin... TTRNA-xALT Cyclophosphamid... Dose-Intensifie... Td vaccine Autologous Hema... | 3 Years - 30 Years | University of Florida | |
| Imaging Brain Tumors With FACBC and Methionine | NCT00597246 | Brain Cancer CNS Cancer | FACBC, Methioni... PET Scan | - | Memorial Sloan Kettering Cancer Center | |
| Valproate and Etoposide for Patients With Neuronal Tumors and Brain Metastases | NCT00513162 | Neuroectodermal... Brain Metastase... Advanced Cancer | Valproate Etoposide | - | M.D. Anderson Cancer Center | |
| Proton Beam Therapy for Chondrosarcoma | NCT00496522 | Chondrosarcoma | Proton Beam The... | - | M.D. Anderson Cancer Center | |
| Venetoclax, Ibrutinib, Prednisone, Obinutuzumab, and Revlimid (VIPOR) for Diffuse Large B-cell Lymphoma Involving the Central Nervous System | NCT05211336 | Primary Diffuse... Aggressive B-ce... | Obinutuzumab Prednisone Lenalidomide Venetoclax Ibrutinib | 18 Years - | National Institutes of Health Clinical Center (CC) | |
| CNS Penetration, PK and PD of Preoperative CC-90010 in Progressive/Recurrent Diffuse Astrocytoma, Anaplastic Astrocytoma and Glioblastoma | NCT04047303 | Astrocytoma Glioblastoma | CC-90010 | 18 Years - | Celgene | |
| Dasatinib Plus Radiation Therapy/Temozolomide in Newly-Diagnosed Glioblastoma | NCT00895960 | Glioblastoma CNS Disease Brain Diseases | Dasatinib RT (Radiotherap... TMZ (Temozolomi... | 18 Years - | M.D. Anderson Cancer Center | |
| A Study to Learn About Dacomitinib in Patients With Non-small Cell Lung Cancer. | NCT06321510 | Lung Cancer | 18 Years - | Pfizer | ||
| Collection of Cerebrospinal Fluid and Tumor Tissue in Subjects With Metastatic Melanoma and Controls | NCT01312506 | Metastatic Mela... CNS Metastases | 18 Years - | University of Pittsburgh | ||
| Venetoclax, Ibrutinib, Prednisone, Obinutuzumab, and Revlimid (VIPOR) for Diffuse Large B-cell Lymphoma Involving the Central Nervous System | NCT05211336 | Primary Diffuse... Aggressive B-ce... | Obinutuzumab Prednisone Lenalidomide Venetoclax Ibrutinib | 18 Years - | National Institutes of Health Clinical Center (CC) | |
| Collection of Cerebrospinal Fluid and Tumor Tissue in Subjects With Metastatic Melanoma and Controls | NCT01312506 | Metastatic Mela... CNS Metastases | 18 Years - | University of Pittsburgh | ||
| Treatment of Brain Metastases From Breast Cancer With Eribulin Mesylate | NCT02581839 | Metastatic Brea... Brain Metastase... | Eribulin Mesyla... MRI Pre-Medication:... Pre-Medication:... | 18 Years - | Case Comprehensive Cancer Center |
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