Spots Global Cancer Trial Database for dna methylation analysis
Every month we try and update this database with for dna methylation analysis cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.
The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
| Study title | NCT ID | Conditions | Interventions | Eligibility | Organization | Link |
|---|---|---|---|---|---|---|
| Radiation Therapy With or Without Temozolomide in Treating Older Patients With Newly Diagnosed Glioblastoma Multiforme | NCT00482677 | Brain and Centr... | temozolomide DNA methylation... quality-of-life... Radiation | 65 Years - 120 Years | Canadian Cancer Trials Group | |
| Biomarkers in Tissue Samples From Young Patients With Acute Myeloid Leukemia | NCT01229956 | Leukemia | DNA methylation... gene expression... microarray anal... reverse transcr... laboratory biom... | 1 Year - 18 Years | Children's Oncology Group | |
| ABT-888, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma Multiforme | NCT00770471 | Brain and Centr... | temozolomide veliparib DNA methylation... gene expression... mutation analys... proteomic profi... high performanc... immunoenzyme te... laboratory biom... mass spectromet... pharmacogenomic... pharmacological... adjuvant therap... radiation thera... | 18 Years - 120 Years | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | |
| Bevacizumab and Lomustine for Recurrent GBM | NCT01290939 | Glioblastoma Mu... Cognition Disor... Disability Eval... | bevacizumab lomustine DNA methylation... laboratory biom... cognitive asses... quality-of-life... | 18 Years - | European Organisation for Research and Treatment of Cancer - EORTC | |
| Bevacizumab and Lomustine for Recurrent GBM | NCT01290939 | Glioblastoma Mu... Cognition Disor... Disability Eval... | bevacizumab lomustine DNA methylation... laboratory biom... cognitive asses... quality-of-life... | 18 Years - | European Organisation for Research and Treatment of Cancer - EORTC | |
| DNA in Predicting Response After Systemic Therapy in Women With Metastatic Breast Cancer | NCT00899548 | Breast Cancer | DNA methylation... microarray anal... polymerase chai... laboratory biom... | 18 Years - | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | |
| Bevacizumab and Lomustine for Recurrent GBM | NCT01290939 | Glioblastoma Mu... Cognition Disor... Disability Eval... | bevacizumab lomustine DNA methylation... laboratory biom... cognitive asses... quality-of-life... | 18 Years - | European Organisation for Research and Treatment of Cancer - EORTC | |
| S8600-S9031-S9333-A, Study of DNA in Samples From Patients With Acute Myeloid Leukemia | NCT01434329 | Leukemia | DNA methylation... gene expression... microarray anal... laboratory biom... medical chart r... | 18 Years - | SWOG Cancer Research Network | |
| Biomarkers in Tissue and Blood Samples From Patients With Early-Stage Non-Small Cell Lung Cancer | NCT01139944 | Lung Cancer | DNA methylation... polymerase chai... laboratory biom... | 18 Years - | Alliance for Clinical Trials in Oncology | |
| Combination Chemotherapy With or Without Gemtuzumab Ozogamicin or Tipifarnib in Treating Patients With Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndromes | NCT00454480 | Leukemia Myelodysplastic... | alemtuzumab arsenic trioxid... azacitidine busulfan clofarabine cytarabine daunorubicin hy... fludarabine pho... gemtuzumab ozog... melphalan tipifarnib DNA methylation... cytogenetic ana... gene expression... mutation analys... diagnostic labo... immunologic tec... allogeneic hema... nonmyeloablativ... | - | National Cancer Institute (NCI) | |
| Tumor DNA and MRI/CT Scan Findings in Patients With Grade III or Grade IV Malignant Glioma | NCT00897611 | High Grade Glio... | DNA methylation... polymerase chai... computed tomogr... magnetic resona... | 18 Years - | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | |
| Clofarabine and Rituximab in Treating Patients With Relapsed Non-Hodgkin Lymphoma | NCT00691652 | Lymphoma | rituximab clofarabine DNA methylation... gene expression... microarray anal... polymerase chai... high performanc... laboratory biom... | 18 Years - 89 Years | OHSU Knight Cancer Institute | |
| DNA Analysis of Tumor Tissue From Patients With Acute Myeloid Leukemia | NCT00897936 | Leukemia | DNA methylation... comparative gen... fluorescence in... microarray anal... polymerase chai... diagnostic labo... immunologic tec... | 18 Years - 120 Years | Eastern Cooperative Oncology Group | |
| Biomarkers in Patients With Rhabdomyosarcoma | NCT01466283 | Sarcoma | DNA methylation... fluorescence in... gene expression... reverse transcr... laboratory biom... | - | Children's Oncology Group | |
| Genetic Testing in Predicting Biomarkers of Recurrence in Patients With Prostate Cancer Undergoing Surgery | NCT00977457 | Prostate Cancer | DNA analysis DNA methylation... RNA analysis gene expression... polymerase chai... diagnostic labo... therapeutic con... | 18 Years - | City of Hope Medical Center | |
| Bevacizumab and Temozolomide in Treating Older Patients With Newly-Diagnosed Glioblastoma Multiforme or Gliosarcoma | NCT01149850 | Giant Cell Glio... Glioblastoma Gliosarcoma | bevacizumab temozolomide laboratory biom... immunohistochem... microarray anal... DNA methylation... | 70 Years - | Jonsson Comprehensive Cancer Center | |
| Biomarker Study of Chemotherapy Resistance and Outcomes in Samples From Older Patients With Acute Myeloid Leukemia | NCT01421875 | Leukemia | DNA methylation... RNA analysis gene expression... microarray anal... nucleic acid se... laboratory biom... | 61 Years - 120 Years | Eastern Cooperative Oncology Group | |
| Studying Genes in Samples From Younger Patients With Adrenocortical Tumor | NCT01528956 | Adrenocortical ... | DNA methylation... RNA analysis gene expression... nucleic acid se... polymorphism an... | - 21 Years | Children's Oncology Group | |
| Studying DNA in Patients With Stage I, Stage II, Stage III, or Stage IV Ovarian Epithelial Cancer | NCT00900289 | Ovarian Cancer | DNA methylation... microarray anal... polymerase chai... immunohistochem... laboratory biom... | 18 Years - | Cancer Research UK, Glasgow | |
| Biomarkers in Tissue and Blood Samples From Patients With Early-Stage Non-Small Cell Lung Cancer | NCT01139944 | Lung Cancer | DNA methylation... polymerase chai... laboratory biom... | 18 Years - | Alliance for Clinical Trials in Oncology | |
| Biomarkers in Young Patients With Neuroblastoma | NCT01169376 | Neuroblastoma | DNA analysis DNA methylation... RNA analysis comparative gen... mutation analys... polymorphism an... | - 30 Years | Children's Oncology Group | |
| Effect of Folate on DNA in Colon Tissue and Blood Samples From Patients at Increased Risk of Developing Colorectal Neoplasia | NCT00611000 | Colorectal Canc... | folic acid DNA methylation... gene expression... microarray anal... polymorphism an... laboratory biom... | 40 Years - 72 Years | National Cancer Institute (NCI) | |
| Biomarkers in Tissue Samples From Patients With High-Risk Wilms Tumor | NCT01118078 | Clear Cell Sarc... Recurrent Wilms... Rhabdoid Tumor ... Stage I Wilms T... Stage II Wilms ... Stage III Wilms... Stage IV Wilms ... Stage V Wilms T... | DNA methylation... gene expression... microarray anal... reverse transcr... diagnostic labo... | - 16 Years | Children's Oncology Group | |
| Phase III Trial of Anaplastic Glioma Without 1p/19q Loss of Heterozygosity (LOH) | NCT00626990 | Brain and Centr... | temozolomide DNA methylation... laboratory biom... adjuvant therap... quality-of-life... radiation thera... | 18 Years - 120 Years | European Organisation for Research and Treatment of Cancer - EORTC | |
| Bevacizumab and Temozolomide in Treating Older Patients With Newly-Diagnosed Glioblastoma Multiforme or Gliosarcoma | NCT01149850 | Giant Cell Glio... Glioblastoma Gliosarcoma | bevacizumab temozolomide laboratory biom... immunohistochem... microarray anal... DNA methylation... | 70 Years - | Jonsson Comprehensive Cancer Center | |
| Studying DNA in Patients With Stage I, Stage II, Stage III, or Stage IV Ovarian Epithelial Cancer | NCT00900289 | Ovarian Cancer | DNA methylation... microarray anal... polymerase chai... immunohistochem... laboratory biom... | 18 Years - | Cancer Research UK, Glasgow | |
| Genetic Testing in Predicting Biomarkers of Recurrence in Patients With Prostate Cancer Undergoing Surgery | NCT00977457 | Prostate Cancer | DNA analysis DNA methylation... RNA analysis gene expression... polymerase chai... diagnostic labo... therapeutic con... | 18 Years - | City of Hope Medical Center | |
| DNA Analysis of Tumor Tissue From Patients With Acute Myeloid Leukemia | NCT00897936 | Leukemia | DNA methylation... comparative gen... fluorescence in... microarray anal... polymerase chai... diagnostic labo... immunologic tec... | 18 Years - 120 Years | Eastern Cooperative Oncology Group | |
| Biomarkers in Patients at Risk of Developing Myelodysplastic Syndrome or Other Disorders and in Healthy Participants | NCT00899327 | Leukemia Myelodysplastic... | DNA methylation... RNA analysis cytogenetic ana... gene expression... mutation analys... polymerase chai... protein express... laboratory biom... | 18 Years - | National Cancer Institute (NCI) | |
| Decitabine, Vaccine Therapy, and Pegylated Liposomal Doxorubicin Hydrochloride in Treating Patients With Recurrent Ovarian Epithelial Cancer, Fallopian Tube Cancer, or Peritoneal Cancer | NCT01673217 | Recurrent Fallo... Recurrent Ovari... Recurrent Prima... | decitabine NY-ESO-1 peptid... pegylated lipos... sargramostim incomplete Freu... immunohistochem... liquid chromato... mass spectromet... reverse transcr... laboratory biom... DNA methylation... enzyme-linked i... | 18 Years - | Roswell Park Cancer Institute | |
| Decitabine and Tretinoin in Treating Patients With Myelodysplastic Syndromes | NCT00382200 | Myelodysplastic... | decitabine tretinoin DNA methylation... cytogenetic ana... microarray anal... flow cytometry immunohistochem... | 18 Years - 120 Years | Memorial Sloan Kettering Cancer Center | |
| Temozolomide in Treating Patients With Invasive Pituitary Tumors | NCT00601289 | Brain and Centr... | temozolomide DNA methylation... microarray anal... protein express... proteomic profi... laboratory biom... | 18 Years - 75 Years | Jonsson Comprehensive Cancer Center | |
| Studying DNA and Outcome in Patients With Advanced Colorectal Cancer Treated With Fluorouracil and Oxaliplatin With or Without Bevacizumab on Clinial Trial E-3200 | NCT00897819 | Colorectal Canc... | DNA methylation... loss of heteroz... microsatellite ... laboratory biom... | 18 Years - 120 Years | Eastern Cooperative Oncology Group | |
| Phase III Trial of Anaplastic Glioma Without 1p/19q Loss of Heterozygosity (LOH) | NCT00626990 | Brain and Centr... | temozolomide DNA methylation... laboratory biom... adjuvant therap... quality-of-life... radiation thera... | 18 Years - 120 Years | European Organisation for Research and Treatment of Cancer - EORTC | |
| Decitabine, Vaccine Therapy, and Pegylated Liposomal Doxorubicin Hydrochloride in Treating Patients With Recurrent Ovarian Epithelial Cancer, Fallopian Tube Cancer, or Peritoneal Cancer | NCT01673217 | Recurrent Fallo... Recurrent Ovari... Recurrent Prima... | decitabine NY-ESO-1 peptid... pegylated lipos... sargramostim incomplete Freu... immunohistochem... liquid chromato... mass spectromet... reverse transcr... laboratory biom... DNA methylation... enzyme-linked i... | 18 Years - | Roswell Park Cancer Institute | |
| Liverpool Lung Project: Risk Factors and Genetic Markers in Healthy Participants and Patients With Lung Cancer | NCT00503958 | Health Status U... Lung Cancer | DNA methylation... DNA stability a... gene expression... epidemiologic s... study of socioe... biopsy evaluation of c... study of high r... | 45 Years - 79 Years | National Cancer Institute (NCI) | |
| Doxorubicin Hydrochloride Liposome in Treating Women With Ductal Carcinoma in Situ Undergoing Surgery | NCT00671476 | Breast Cancer | pegylated lipos... DNA methylation... TdT-mediated dU... fluorescence in... loss of heteroz... polymerase chai... immunoenzyme te... immunohistochem... laboratory biom... breast duct lav... neoadjuvant the... therapeutic con... | 18 Years - | National Cancer Institute (NCI) | |
| Studying Biomarkers in Samples From Younger Patients With Malignant Germ Cell Tumor Progression | NCT01433224 | Childhood Germ ... Extragonadal Ge... Ovarian Cancer Testicular Germ... | DNA methylation... RNA analysis mutation analys... nucleic acid se... polymerase chai... polymorphism an... laboratory biom... medical chart r... | - | Children's Oncology Group | |
| Biomarkers in Samples From Adult Patients With Acute Myeloid Leukemia Who Failed Existing Standard-of-Care Treatment | NCT01421862 | Leukemia | DNA methylation... RNA analysis gene expression... microarray anal... mutation analys... nucleic acid se... laboratory biom... | 18 Years - 65 Years | National Cancer Institute (NCI) | |
| Cidofovir in Treating HIV-Infected Patients With High-Grade Squamous Intraepithelial Lesions of the Skin Near the Anus | NCT00550589 | Anal Cancer Precancerous Co... | cidofovir DNA methylation... gene expression... polymerase chai... biopsy histopathologic... | 18 Years - 120 Years | AIDS Malignancy Consortium | |
| Liverpool Lung Project: Risk Factors and Genetic Markers in Healthy Participants and Patients With Lung Cancer | NCT00503958 | Health Status U... Lung Cancer | DNA methylation... DNA stability a... gene expression... epidemiologic s... study of socioe... biopsy evaluation of c... study of high r... | 45 Years - 79 Years | National Cancer Institute (NCI) | |
| Low-Dose Azacitidine, Lenalidomide, and Low-Dose Dexamethasone in Relapsed or Refractory Multiple Myeloma | NCT01155583 | Refractory Mult... | azacitidine lenalidomide dexamethasone DNA methylation... gene expression... bone marrow asp... immunohistochem... reverse transcr... flow cytometry | 18 Years - | Case Comprehensive Cancer Center | |
| Biomarkers in Tumor Tissue Samples From Young Patients With Very Low Risk Wilms Tumors | NCT01004783 | Kidney Cancer | DNA methylation... gene expression... loss of heteroz... microarray anal... mutation analys... polymerase chai... reverse transcr... laboratory biom... | - 18 Years | Children's Oncology Group | |
| Diagnostic and Monitoring Significance of ctDNA Methylation Analysis by NGS in Benign and Malignant Pulmonary Nodules | NCT03651986 | Pulmonary Nodul... | ctDNA methylati... | 18 Years - | AnchorDx Medical Co., Ltd. | |
| Low-Dose Azacitidine, Lenalidomide, and Low-Dose Dexamethasone in Relapsed or Refractory Multiple Myeloma | NCT01155583 | Refractory Mult... | azacitidine lenalidomide dexamethasone DNA methylation... gene expression... bone marrow asp... immunohistochem... reverse transcr... flow cytometry | 18 Years - | Case Comprehensive Cancer Center | |
| 5-Fluoro-2'-Deoxycytidine and Tetrahydrouridine in Treating Patients With Acute Myeloid Leukemia or Myelodysplastic Syndromes | NCT01041443 | Adult Acute Mye... de Novo Myelody... Previously Trea... Recurrent Adult... Secondary Acute... Secondary Myelo... Untreated Adult... | 5-fluoro-2-deox... tetrahydrouridi... laboratory biom... reverse transcr... DNA methylation... | 18 Years - | City of Hope Medical Center | |
| Biomarkers in Predicting Response to Chemotherapy in Patients With Advanced or Metastatic Melanoma Previously Treated With Carboplatin and Paclitaxel With or Without Sorafenib Tosylate | NCT01209299 | Melanoma (Skin) | DNA methylation... gene expression... laboratory biom... | 18 Years - 120 Years | Eastern Cooperative Oncology Group | |
| S9031-S9126-S9333-S9500-A, Studying Bone Marrow and Blood Samples From Patients With Acute Myeloid Leukemia | NCT00899171 | Leukemia | DNA analysis DNA methylation... RNA analysis gene expression... reverse transcr... laboratory biom... | 18 Years - | SWOG Cancer Research Network | |
| Effect of Surgery, Radiation Therapy, Chemotherapy, and Hormone Therapy on Biomarkers in Women With Stage I, Stage II, Stage III Breast Cancer, or Ductal Carcinoma In Situ That Can Be Removed By Surgery | NCT00373191 | Breast Cancer | chemotherapy endocrine thera... DNA methylation... protein analysi... laboratory biom... questionnaire a... adjuvant therap... conventional su... radiation thera... | 18 Years - | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | |
| Studying Genes Using Cord Blood and Placenta Samples From Relatively Healthy Newborns and Samples From Younger Patients With Wilms Tumor | NCT01576211 | Kidney Cancer | DNA methylation... RNA analysis allele-specific... gene expression... nucleic acid se... polymorphism an... laboratory biom... | - 21 Years | Children's Oncology Group | |
| Fludeoxyglucose F 18 PET Imaging in Determining Protein and Gene Expression Signatures in Patients With Premalignant Polyps or Colon Cancer | NCT00550628 | Colorectal Canc... Neoplasm of Unc... | DNA methylation... fluorescence in... gene expression... polymerase chai... protein express... reverse transcr... diagnostic labo... immunoenzyme te... immunohistochem... biopsy therapeutic con... fludeoxyglucose... | 15 Years - | Memorial Sloan Kettering Cancer Center | |
| Diagnostic and Monitoring Significance of ctDNA Methylation Analysis by NGS in Benign and Malignant Pulmonary Nodules | NCT03651986 | Pulmonary Nodul... | ctDNA methylati... | 18 Years - | AnchorDx Medical Co., Ltd. | |
| Temozolomide in Treating Patients With Invasive Pituitary Tumors | NCT00601289 | Brain and Centr... | temozolomide DNA methylation... microarray anal... protein express... proteomic profi... laboratory biom... | 18 Years - 75 Years | Jonsson Comprehensive Cancer Center | |
| Cidofovir in Treating HIV-Infected Patients With High-Grade Squamous Intraepithelial Lesions of the Skin Near the Anus | NCT00550589 | Anal Cancer Precancerous Co... | cidofovir DNA methylation... gene expression... polymerase chai... biopsy histopathologic... | 18 Years - 120 Years | AIDS Malignancy Consortium | |
| S8600-S9031-S9333-A, Study of DNA in Samples From Patients With Acute Myeloid Leukemia | NCT01434329 | Leukemia | DNA methylation... gene expression... microarray anal... laboratory biom... medical chart r... | 18 Years - | SWOG Cancer Research Network | |
| DNA in Predicting Response After Systemic Therapy in Women With Metastatic Breast Cancer | NCT00899548 | Breast Cancer | DNA methylation... microarray anal... polymerase chai... laboratory biom... | 18 Years - | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | |
| DNA Tests in Detecting Disseminated Disease in Tumor, Blood, and Bone Marrow Samples From Patients With Rhabdomyosarcoma | NCT01419509 | Sarcoma | DNA methylation... microarray anal... polymerase chai... laboratory biom... | - 18 Years | Children's Oncology Group | |
| Biomarkers in Patients With Rhabdomyosarcoma | NCT01466283 | Sarcoma | DNA methylation... fluorescence in... gene expression... reverse transcr... laboratory biom... | - | Children's Oncology Group | |
| 5-Fluoro-2'-Deoxycytidine and Tetrahydrouridine in Treating Patients With Acute Myeloid Leukemia or Myelodysplastic Syndromes | NCT01041443 | Adult Acute Mye... de Novo Myelody... Previously Trea... Recurrent Adult... Secondary Acute... Secondary Myelo... Untreated Adult... | 5-fluoro-2-deox... tetrahydrouridi... laboratory biom... reverse transcr... DNA methylation... | 18 Years - | City of Hope Medical Center |
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