Spots Global Cancer Trial Database for elderly patients
Every month we try and update this database with for elderly patients cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.
The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
| Study title | NCT ID | Conditions | Interventions | Eligibility | Organization | Link |
|---|---|---|---|---|---|---|
| Effects of BIS Closed Loop Target Controlled Infusion on Perioperative Inflammatory Response and Prognosis of Elderly Patients Undergoing Laparoscopic Radical Gastrectomy for Gastric Cancer | NCT05173909 | The Effect of B... | BIS closed-loop... | 65 Years - | Shaoxing Hospital of Zhejiang University | |
| R-CHOP Versus R-mini-CEOP in Elderly Patients(>65)With DLBCL | NCT01148446 | Elderly Patient... Diffuse Large B... | Cyclophosphamid... Cyclophosphamid... Doxorubicin Vincristine Prednisone Prednisone Epirubicin Vinblastine Rituximab G-CSF | 66 Years - 80 Years | Fondazione Italiana Linfomi - ETS | |
| Epidural Anesthesia and Long-term Outcomes in Elderly Patients After Surgery | NCT03335826 | Elderly Patient... Solid Organ Can... Surgical Resect... Epidural Anesth... Long-term Outco... | Combined epidur... General anesthe... | 60 Years - 90 Years | Peking University First Hospital | |
| Phase I/II Study of Oral S-1 Plus Docetaxel in Elderly Patients With Advanced Gastric Cancer. | NCT00209729 | Gastric Cancer | Taxotere TS-1 | 76 Years - 80 Years | Hokkaido Gastrointestinal Cancer Study Group | |
| Pharmacokinetic Study of Capecitabine in Elderly Cancer Patient (≥ 75 Years) | NCT00812864 | Breast Cancer Colorectal Canc... | Capecitabine | 75 Years - | University Hospital, Limoges | |
| A Randomized Study With Oral Melphalan + Prednisone (MP) Versus Melphalan, + Prednisone + Thalidomide (MPT) for Newly Diagnosesd Elderly Patients With Multiple Myeloma | NCT01274403 | Multiple Myelom... | Melphalan, Pred... | 65 Years - | Gruppo Italiano Studio Linfomi | |
| Plerixafor and Clofarabine in Frontline Treatment of Elderly Patients With Acute Myelogenous Leukemia (AML) | NCT01160354 | Acute Myelogeno... | Plerixafor Clofarabine | 60 Years - | M.D. Anderson Cancer Center | |
| Rituximab and Bendamustine in Very Elderly Patients or Elderly Medically Non Fit Patients With Aggressive B-cell Lymphoma | NCT01686321 | Aggressive Lymp... | Bendamustine an... | 60 Years - | University of Göttingen | |
| GOELAMS SA4 Study: the Role of Fludarabine in the Treatment of Acute Myeloid Leukemia in the Elderly | NCT00925873 | Acute Myeloid L... | Active comparat... Experimental (f... | 60 Years - 75 Years | French Innovative Leukemia Organisation | |
| Preoperative Chemoradiotherapy With Raltitrexed for Intermediate or Locally Advanced Rectal Cancer in the Fit Elderly | NCT02992886 | Rectal Neoplasm... | Preoperative ra... Raltitrexed Pelvic surgery | 71 Years - | ChineseAMS | |
| Chemoradiotherapy in Elderly Patients With Oesophagus Cancer | NCT02735057 | Oesophagus Canc... Elderly Patient... | Carboplatin | 75 Years - 100 Years | Centre Hospitalier Universitaire de Besancon | |
| Autologous Stem Cell Transplantation for Myeloma Patients Over 65 Years | NCT01671826 | Newly Diagnosed... | 18 Years - | Assistance Publique - Hôpitaux de Paris | ||
| Dexamethasone Added to Intensive Chemotherapy in Older Patients With Acute Myeloid Leukemia (AML) | NCT03609060 | Acute Myeloid L... | Dexamethasone | 60 Years - | French Innovative Leukemia Organisation | |
| Sintilimab After Concurrent Chemoradiotherapy in Elderly Patients With Esophageal Squamous Cell Carcinoma | NCT06413342 | Esophageal Canc... Chemoradiothera... Sintilimab Immunotherapy Elderly Patient... | Sintilimab | 70 Years - 85 Years | Zhejiang Cancer Hospital | |
| Chemotherapy for Elderly Patients Diagnosed With Localized HER2 Positive Breast Cancer | NCT02102438 | Breast Cancer HER-2 Positive ... | Trastuzumab Weekly Paclitax... Carboplatin | 65 Years - | Instituto do Cancer do Estado de São Paulo | |
| Capnographic Monitoring in Gastrointestinal Endoscopy for Elderly Patients | NCT05030870 | Hypoxia Gastric Cancer Gastric Polyp Colon Polyp Colon Cancer Esophageal Canc... | Capnography mon... Standard monito... | 65 Years - 79 Years | RenJi Hospital | |
| Apatinib for the Elderly Advanced Gastric Cancer | NCT03104283 | Gastric Cancer | Apatinib | 60 Years - | Affiliated Hospital of Qinghai University | |
| Phase III Study of Concurrent Radiotherapy in Elderly Patients With Esophageal Squamous Cell Carcinoma (ESO-Shanghai 15) | NCT04519905 | Esophageal Squa... Chemoradiothera... Survival | Paclitaxel plus... radiotherapy | 76 Years - | Fudan University | |
| Phase I/II Study of Oral S-1 Plus Docetaxel in Elderly Patients With Advanced Gastric Cancer. | NCT00209729 | Gastric Cancer | Taxotere TS-1 | 76 Years - 80 Years | Hokkaido Gastrointestinal Cancer Study Group | |
| Study for Elderly (≥ 65 Years) Patients With Classical Hodgkin Lymphoma Undergoing CGA at Diagnosis | NCT03552003 | Classical Hodgk... | Treatment for c... | 65 Years - | Fondazione Italiana Linfomi - ETS | |
| Capnographic Monitoring in Gastrointestinal Endoscopy for Elderly Patients | NCT05030870 | Hypoxia Gastric Cancer Gastric Polyp Colon Polyp Colon Cancer Esophageal Canc... | Capnography mon... Standard monito... | 65 Years - 79 Years | RenJi Hospital | |
| Feasibility of a Chemotherapy With Docetaxel-Prednisone for Castration-resistant Metastatic Prostate Cancer Elderly Patients | NCT01254513 | Prostate Cancer | Docetaxel every... Docetaxel weekl... | 75 Years - | UNICANCER | |
| Study for Elderly (≥ 65 Years) Patients With Classical Hodgkin Lymphoma Undergoing CGA at Diagnosis | NCT03552003 | Classical Hodgk... | Treatment for c... | 65 Years - | Fondazione Italiana Linfomi - ETS | |
| Trial to Evaluate Radiotherapy With or Without CBDCA in Elderly Patients With Non-Small Cell Lung Cancer (JCOG0301) | NCT00132665 | Non-Small-Cell ... | A: Radiotherapy... B: CBDCA and Ra... | 71 Years - | Japan Clinical Oncology Group | |
| A Study to Determine Final Geriatric Assessment in Haematology (GAH) Score as a Tool for Predicting Tolerance to Treatment in Elderly Patients (≥ 65 Years) With Haematologic Neoplasms | NCT02842229 | Myelodysplastic... Leukemia Myeloi... Multiple Myelom... Leukemia, Lymph... | 65 Years - | Celgene | ||
| Chemotherapy for Elderly Patients Diagnosed With Localized HER2 Positive Breast Cancer | NCT02102438 | Breast Cancer HER-2 Positive ... | Trastuzumab Weekly Paclitax... Carboplatin | 65 Years - | Instituto do Cancer do Estado de São Paulo | |
| Retrospective Study: Efficacy and Safety of Chlorambucil + Rituximab in CLL Patients | NCT01862445 | CLL B-cell Small Lymphocyt... Untreated B-CLL Elderly Patient... | 18 Years - | Gruppo Italiano Malattie EMatologiche dell'Adulto | ||
| Efficacy and Safety of Cladribine in Combination With CAG in Newly Diagnosed Unfit Patients With AML | NCT04254640 | Acute Myeloid L... Elderly Patient... Newly Diagnosed | Cladribine Inje... Aclarubicin G-CSF cytarabine | 18 Years - 90 Years | Sun Yat-sen University | |
| Pemetrexed With or Without Carboplatin for Elderly Non-squamous Non-small Cell Lung Cancer | NCT01593293 | Non-small Cell ... | PemCarbo Pem only | 70 Years - | Asan Medical Center | |
| Nimotuzumab Combined With VMAT in Elderly Patients With Nasopharyngeal Carcinoma | NCT03915132 | Nasopharyngeal ... | Nimotuzumab VMAT | 70 Years - | ChineseAMS | |
| Frailty and Body Composition in the Elderly Cancer Patients Treated With Chemotherapy | NCT02806154 | Cancer | DEXA | 70 Years - | University Hospital, Toulouse | |
| Concomitant Radio-chemotherapy in the Elderly | NCT01029678 | Non Small Cell ... | Cisplatin IV Vinorelbine Radiotherapy | 70 Years - | University Hospital, Limoges | |
| Treatment of Newly Diagnosed Elderly Patients With Multiple Myeloma | NCT00367185 | Multiple Myelom... | Thalidomide | 65 Years - 75 Years | University Hospital, Lille | |
| Antineoplastic Drugs in Elderly Patients | NCT05467189 | Cancer | Busulfan, Pacli... | 65 Years - 100 Years | Shandong University | |
| Plerixafor and Clofarabine in Frontline Treatment of Elderly Patients With Acute Myelogenous Leukemia (AML) | NCT01160354 | Acute Myelogeno... | Plerixafor Clofarabine | 60 Years - | M.D. Anderson Cancer Center | |
| Preoperative Chemoradiotherapy With Raltitrexed for Intermediate or Locally Advanced Rectal Cancer in the Fit Elderly | NCT02992886 | Rectal Neoplasm... | Preoperative ra... Raltitrexed Pelvic surgery | 71 Years - | ChineseAMS | |
| Are the Fried Criteria Predictive of a Functional Decline in Older People With Solid Malignant Tumors? | NCT02662179 | Elderly Patient... | Quality of life... Functional decl... Physical declin... Cognitive decli... | 70 Years - | Brugmann University Hospital | |
| Rituximab Maintenance Versus Observation After First-line Immunochemotherapy by FCR in Older Patients With Chronic Lymphocytic Leukemia | NCT00645606 | Leukemia | Rituximab | 65 Years - | University Hospital, Tours | |
| EFficacy and Impact on Function of Two Different Doses of Nab-paclitaxEl in Elderly With advanCed breasT Cancer | NCT02783222 | Breast Cancer | Nab-paclitaxel | 65 Years - | Fondazione Sandro Pitigliani | |
| Rituximab Augmentation Following R-CHOP Induction Chemotherapy in Extremely Elderly Patients With Diffuse Large B Cell Lymphoma | NCT01181999 | Lymphoma, Large... | rituximab | 70 Years - | Chonnam National University Hospital | |
| The Efficacy and Safety of ZR2 Versus R-miniCHOP in the Treatment of Unfit or Frail de Novo Diffuse Large B-cell Lymphoma Patients Aged Older Than or Equal to 70 Years | NCT05179733 | Diffuse Large B... | six courses of ... six courses of ... | 70 Years - | Ruijin Hospital | |
| Apatinib for the Elderly Advanced Gastric Cancer | NCT03104283 | Gastric Cancer | Apatinib | 60 Years - | Affiliated Hospital of Qinghai University | |
| Frailty and Body Composition in the Elderly Cancer Patients Treated With Chemotherapy | NCT02806154 | Cancer | DEXA | 70 Years - | University Hospital, Toulouse | |
| The Efficacy and Safety of ZR2 Versus R-miniCHOP in the Treatment of Unfit or Frail de Novo Diffuse Large B-cell Lymphoma Patients Aged Older Than or Equal to 70 Years | NCT05179733 | Diffuse Large B... | six courses of ... six courses of ... | 70 Years - | Ruijin Hospital | |
| Tislelizumab Plus Chemotherapy as Postoperative Adjuvant Therapy in Elderly Patients With LA GC/GEJC | NCT06238167 | Gastric Cancer | Tislelizumab S-1 therapy low dose SOX th... | 70 Years - | First Affiliated Hospital of Wenzhou Medical University | |
| Adjuvant Systemic Treatment for (ER)-Positive HER2-negative Breast Carcinoma in Women Over 70 According to Genomic Grade (GG): Chemotherapy + Endocrine Treatment Versus Endocrine Treatment | NCT01564056 | Breast Cancer | HORMONOTHERAPY CHEMOTHERAPY th... | 70 Years - | UNICANCER | |
| Cetuximab for Elderly Patients With mCRC | NCT01718808 | Metastatic Colo... | Cetuximab Capecitabine | 70 Years - | Swiss Group for Clinical Cancer Research | |
| Decitabine Maintenance in Elderly Acute Myeloid Leukemia Patients | NCT01149408 | Acute Myeloid L... AML | Decitabine (Dac... | 60 Years - | University of Utah | |
| Impacts on Health Outcomes and Resources Utilization of Hospital-at-home for Elderly Patients With Multiple Myeloma | NCT03490084 | Multiple Myelom... | Association of ... Day hospitaliza... | 65 Years - | Assistance Publique - Hôpitaux de Paris | |
| Single-drug Chemotherapy Plus Immunotherapy in Metastatic Non-small Cell Lung Cancer Elderly Patients | NCT06032052 | Elderly Patient... Metastatic Lung... | Single drug che... | 65 Years - | Hubei Cancer Hospital | |
| Adjuvant Low Dose Total Body Irradiation in Elderly Patients With Diffuse Large B-Cell Lymphoma | NCT00834951 | Non Hodgkin's L... | Low dose total ... | 60 Years - | University of Aarhus | |
| Lenalidomide and Dexamethasone Versus Melphalan Prednisone and Lenalidomide Versus Cyclophosphamide, Prednisone and Lenalidomide in Elderly Multiple Myeloma Patients | NCT01093196 | Multiple Myelom... | Melphalan, Pred... Cyclophosphamid... Lenalidomide, d... | 18 Years - | Fondazione EMN Italy Onlus | |
| EFficacy and Impact on Function of Two Different Doses of Nab-paclitaxEl in Elderly With advanCed breasT Cancer | NCT02783222 | Breast Cancer | Nab-paclitaxel | 65 Years - | Fondazione Sandro Pitigliani | |
| Velcade, Melphalan, Prednisone And Thalidomide Versus Velcade, Melphalan, Prednisone in Multiple Myeloma Patients | NCT01063179 | Multiple Myelom... | Bortezomib, Mel... Bortezomib, Mel... | 65 Years - 100 Years | Fondazione EMN Italy Onlus | |
| Trial of Pimasertib in Hematological Malignancies | NCT00957580 | Leukemia, Myelo... Hematologic Neo... | Pimasertib Pimasertib Pimasertib Pimasertib Pimasertib | 18 Years - | EMD Serono | |
| Rituximab, Bendamustine and Cytarabine Followed by Venetoclax in High Risk Elderly Patients With MCL | NCT03567876 | Lymphoma, Mantl... | Venetoclax | 18 Years - | Fondazione Italiana Linfomi - ETS | |
| Erlotinib Versus Carboplatin/Vinorelbine in Elderly Patients With Advanced Non-Small Cell Lung Cancer (NSCLC) | NCT00678964 | Non-Small Cell ... | Erlotinib Vinorelbine and... | 70 Years - | LungenClinic Grosshansdorf | |
| A Randomized Study With Oral Melphalan + Prednisone (MP) Versus Melphalan, + Prednisone + Thalidomide (MPT) for Newly Diagnosesd Elderly Patients With Multiple Myeloma | NCT01274403 | Multiple Myelom... | Melphalan, Pred... | 65 Years - | Gruppo Italiano Studio Linfomi | |
| Remote Monitoring for Ambulatory Care of Elderly Patients With Cancer | NCT04913259 | Cancer | Remote monitori... | 65 Years - | Institut Bergonié | |
| Lenalidomide and Dexamethasone Versus Melphalan Prednisone and Lenalidomide Versus Cyclophosphamide, Prednisone and Lenalidomide in Elderly Multiple Myeloma Patients | NCT01093196 | Multiple Myelom... | Melphalan, Pred... Cyclophosphamid... Lenalidomide, d... | 18 Years - | Fondazione EMN Italy Onlus | |
| Adjuvant Capecitabine in Elderly Patients With Breast Cancer: a Phase II Study | NCT00263705 | Elderly Patient... Breast Cancer | Adjuvant capeci... capecitabine in... | 70 Years - | Jules Bordet Institute | |
| Bevacizumab and Capecitabine in Treatment of Elderly Patients With Metastatic Breast Cancer | NCT01195298 | Breast Cancer Metastasis | Capecitabine an... | 70 Years - | South Eastern European Research Oncology Group | |
| Health Status Evaluation for Cancer Survivors by Non-intrusive Sensing System | NCT02175823 | Cancer | 65 Years - | National Taiwan University Hospital | ||
| A Retrospective Analysis of Spinal Anaesthesia for TURBT Procedures in Elderly Patients | NCT03221829 | Spinal Anaesthe... Bladder Tumor Transurethral R... | 60 Years - | Medical University of Warsaw | ||
| Treatment of Newly Diagnosed Elderly Patients With Multiple Myeloma | NCT00367185 | Multiple Myelom... | Thalidomide | 65 Years - 75 Years | University Hospital, Lille | |
| Efficacy of Adapted Physical Activity on a Walking Platform in Elderly Patients HOspitalized for Cancer Surgery | NCT06201884 | Oncology Elderly Patient... Surgery | Early rehabilit... | 65 Years - | Centre Francois Baclesse | |
| Geriatric Intervention Contribution on Quality of Life of Elderly Patients With Metastatic Neoplasia | NCT03743961 | Systemic Treatm... Metastatic Neop... Elderly Patient... | geriatric inter... | 75 Years - | Institut de Cancérologie de la Loire | |
| Velcade, Melphalan, Prednisone And Thalidomide Versus Velcade, Melphalan, Prednisone in Multiple Myeloma Patients | NCT01063179 | Multiple Myelom... | Bortezomib, Mel... Bortezomib, Mel... | 65 Years - 100 Years | Fondazione EMN Italy Onlus | |
| Study of Teclistamab in Combination in Elderly Patients With Multiple Myeloma | NCT05572229 | Multiple Myelom... | Teclistamab Daratumumab Lenalidomide | 65 Years - | University Hospital, Lille | |
| Epidural Anesthesia and Long-term Outcomes in Elderly Patients After Surgery | NCT03335826 | Elderly Patient... Solid Organ Can... Surgical Resect... Epidural Anesth... Long-term Outco... | Combined epidur... General anesthe... | 60 Years - 90 Years | Peking University First Hospital | |
| Chemotherapy for Elderly Patients Diagnosed With Localized HER2 Positive Breast Cancer | NCT02102438 | Breast Cancer HER-2 Positive ... | Trastuzumab Weekly Paclitax... Carboplatin | 65 Years - | Instituto do Cancer do Estado de São Paulo | |
| QoL in mCRC Elderly Patients Receiving First-line Therapy Based on Simplified Geriatric Parameters. | NCT03828227 | Elderly Patient... Metastatic Colo... Quality of Life | OPTIMOX-bevaciz... Capecitabine pl... | 75 Years - | GERCOR - Multidisciplinary Oncology Cooperative Group | |
| Efficacy and Safety of Cladribine in Combination With CAG in Newly Diagnosed Unfit Patients With AML | NCT04254640 | Acute Myeloid L... Elderly Patient... Newly Diagnosed | Cladribine Inje... Aclarubicin G-CSF cytarabine | 18 Years - 90 Years | Sun Yat-sen University | |
| Geriatric Intervention Contribution on Quality of Life of Elderly Patients With Metastatic Neoplasia | NCT03743961 | Systemic Treatm... Metastatic Neop... Elderly Patient... | geriatric inter... | 75 Years - | Institut de Cancérologie de la Loire | |
| Clinical Outcomes of Laparoscopic D1 Versus D2 Lymphadenectomy for Elderly Patients With Advanced Gastric Cancer | NCT03290209 | Stomach Neoplas... | Laparoscopic D1... Laparoscopic D2... | 75 Years - | Fujian Medical University | |
| Tislelizumab Plus Chemotherapy as Postoperative Adjuvant Therapy in Elderly Patients With LA GC/GEJC | NCT06238167 | Gastric Cancer | Tislelizumab S-1 therapy low dose SOX th... | 70 Years - | First Affiliated Hospital of Wenzhou Medical University | |
| Study of Teclistamab in Combination in Elderly Patients With Multiple Myeloma | NCT05572229 | Multiple Myelom... | Teclistamab Daratumumab Lenalidomide | 65 Years - | University Hospital, Lille | |
| Induction Chemotherapy (R-CHOP Vs. R-FC) Followed by Interferon Maintenance Versus Rituximab Maintenance in MCL | NCT00209209 | Lymphoma, Mantl... | Rituximab Cyclophosphamid... Doxorubicin Vincristine Prednisone Fludarabine Interferon-alph... pegylated formu... chemotherapy: R... chemotherapy: R... Interferon main... Rituximab maint... | 60 Years - | European Mantle Cell Lymphoma Network | |
| S-1/Leucovorin (SL) Versus sLV5FU2 as the First-line Treatment for Elderly Patients With Colorectal Cancer | NCT01193452 | Colorectal Canc... | S-1, Leucovorin leucovorin, 5-f... | 65 Years - | Fudan University | |
| Trial of Pimasertib in Hematological Malignancies | NCT00957580 | Leukemia, Myelo... Hematologic Neo... | Pimasertib Pimasertib Pimasertib Pimasertib Pimasertib | 18 Years - | EMD Serono |
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