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Spots Global Cancer Trial Database for liposomal irinotecan

Every month we try and update this database with for liposomal irinotecan cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.

Study titleNCT IDConditionsInterventionsEligibilityOrganizationLink
Second-line Therapy for Patients With Progressive Poorly Differentiated Extra-pulmonary Neuroendocrine CarcinomaNCT03837977
Oncology
Neuroendocrine ...
Liposomal Irino...
Fluorouracil
Folinic Acid
Docetaxel
18 Years - The Christie NHS Foundation Trust
Liposomal iRInotecan, Carboplatin or oXaliplatin for Esophagogastric CancerNCT03764553
Esophageal Canc...
Liposomal Irino...
Carboplatin
Capecitabine
Oxaliplatin
5-fluorouracil
Leucovorin
18 Years - Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Irinotecan Liposome Combined With Anlotinib as Second-line Regimen for SCLCNCT06258642
Small Cell Lung...
Irinotecan Lipo...
Anlotinib
18 Years - 75 YearsFudan University
Liposomal Irinotecan With TAS102 and Bevacizumab for Patients With Metastatic Colorectal CancerNCT05854498
Metastatic Colo...
Liposomal irino...
TAS102
Bevacizumab
18 Years - University of Wisconsin, Madison
A Study of the Safety and Activity of Liposomal Irinotecan in Combination With the 5-FU and Oxaliplatin in the Preoperative Treatment of Pancreatic AdenocarcinomaNCT03483038
Pancreatic Aden...
Liposomal Irino...
FOLFOX regimen
18 Years - 99 YearsUniversity of Florida
Comparing Two Treatment Combinations, Gemcitabine and Nab-Paclitaxel With 5-Fluorouracil, Leucovorin, and Liposomal Irinotecan for Older Patients With Pancreatic Cancer That Has SpreadNCT04233866
Metastatic Panc...
Stage IV Pancre...
Fluorouracil
Gemcitabine
Gemcitabine Hyd...
Leucovorin
Leucovorin Calc...
Liposomal Irino...
Nab-paclitaxel
Quality-of-Life...
Questionnaire A...
70 Years - Eastern Cooperative Oncology Group
Liposomal Irinotecan With TAS102 and Bevacizumab for Patients With Metastatic Colorectal CancerNCT05854498
Metastatic Colo...
Liposomal irino...
TAS102
Bevacizumab
18 Years - University of Wisconsin, Madison
Liposomal Irinotecan Plus Bevacizumab in Irinotecan-refractory Metastatic Colorectal CancerNCT06434090
Colorectal Canc...
Liposomal irino...
Bevacizumab
18 Years - Sun Yat-sen University
Liposomal Irinotecan, S-1, and Oxaliplatin in Advanced Pancreatic AdenocarcinomaNCT04662112
Pancreatic Canc...
Pancreatic Duct...
NASOX
19 Years - Asan Medical Center
A Study of the Safety and Activity of Liposomal Irinotecan in Combination With the 5-FU and Oxaliplatin in the Preoperative Treatment of Pancreatic AdenocarcinomaNCT03483038
Pancreatic Aden...
Liposomal Irino...
FOLFOX regimen
18 Years - 99 YearsUniversity of Florida
Neoadjuvant Chemoradiation With Nal-IRI and Capecitabine Guided by UGT1A1 Status in Patients With Rectal CancerNCT06210971
Rectal Cancer
liposomal irino...
Capecitabine
Radiation threa...
18 Years - 80 YearsHebei Medical University Fourth Hospital
Liposomal Irinotecan, Fluorouracil and Leucovorin in Treating Patients With Refractory Advanced High Grade Neuroendocrine Cancer of Gastrointestinal, Unknown, or Pancreatic OriginNCT03736720
Locally Advance...
Locally Advance...
Metastatic Dige...
Metastatic Panc...
Refractory Dige...
Refractory Panc...
Unresectable Di...
Unresectable Pa...
Fluorouracil
Leucovorin
Liposomal Irino...
Quality-of-Life...
18 Years - Roswell Park Cancer Institute
Liposomal Irinotecan Plus Bevacizumab in Irinotecan-refractory Metastatic Colorectal CancerNCT06434090
Colorectal Canc...
Liposomal irino...
Bevacizumab
18 Years - Sun Yat-sen University
A Study of the Safety and Activity of Liposomal Irinotecan in Combination With the 5-FU and Oxaliplatin in the Preoperative Treatment of Pancreatic AdenocarcinomaNCT03483038
Pancreatic Aden...
Liposomal Irino...
FOLFOX regimen
18 Years - 99 YearsUniversity of Florida
Liposomal Irinotecan and Leucovorin/5-fluorouracil Plus Bevacizumab in Metastatic Colorectal CancerNCT06184698
Colorectal Canc...
liposomal irino...
5-FU
LV
Bevacizumab
18 Years - 80 YearsHebei Medical University Fourth Hospital
Combination Liposomal Irinotecan and Pembrolizumab For Triple-Negative Breast Cancer (TNBC) With Brain Metastases (BM)NCT05255666
Triple Negative...
Brain Metastase...
Pembrolizumab
Liposomal Irino...
18 Years - Washington University School of Medicine
Liposomal Irinotecan and Capecitabine Plus Bevacizumab as Second-line Therapy in Metastatic Colorectal CancerNCT06192680
Colorectal Canc...
Liposomal irino...
Capecitabine
Bevacizumab
18 Years - 80 YearsHarbin Medical University
Comparing Two Treatment Combinations, Gemcitabine and Nab-Paclitaxel With 5-Fluorouracil, Leucovorin, and Liposomal Irinotecan for Older Patients With Pancreatic Cancer That Has SpreadNCT04233866
Metastatic Panc...
Stage IV Pancre...
Fluorouracil
Gemcitabine
Gemcitabine Hyd...
Leucovorin
Leucovorin Calc...
Liposomal Irino...
Nab-paclitaxel
Quality-of-Life...
Questionnaire A...
70 Years - Eastern Cooperative Oncology Group
Liposomal Irinotecan and Leucovorin/5-fluorouracil Plus Bevacizumab in Metastatic Colorectal CancerNCT06184698
Colorectal Canc...
liposomal irino...
5-FU
LV
Bevacizumab
18 Years - 80 YearsHebei Medical University Fourth Hospital
MM-398 and Ramucirumab in Treating Patients With Gastric Cancer or Gastroesophageal Junction AdenocarcinomaNCT03739801
Locally Advance...
Metastatic Gast...
Metastatic Unre...
Unresectable Ga...
Gastric Adenoca...
Gastroesophagea...
Liposomal Irino...
Quality-of-Life...
Questionnaire A...
Ramucirumab
18 Years - University of Southern California
Second Line Treatment With Nal-IRI and S1 in Pancreatic CancerNCT03986294
Metastatic Panc...
S1 + Nal-IRI
Nal-IRI+Leucovo...
18 Years - Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
A Phase I Trial of Nanoliposomal CPT-11 (NL CPT-11) in Patients With Recurrent High-Grade GliomasNCT00734682
Glioblastoma
Gliosarcoma
Anaplastic Astr...
Anaplastic Olig...
Nanoliposomal C...
18 Years - University of California, San Francisco
Treatment of Newly Diagnosed Rhabdomyosarcoma Using Molecular Risk Stratification and Liposomal Irinotecan Based Therapy in Children With Intermediate and High Risk DiseaseNCT06023641
Rhabdomyosarcom...
Vincristine
Dactinomycin
Cyclophosphamid...
Surgical Resect...
Proton beam rad...
Liposomal irino...
Vinorelbine
Temozolomide
Filgrastim, peg...
- 22 YearsSt. Jude Children's Research Hospital
Irinotecan Liposome Combined With Anlotinib as Second-line Regimen for SCLCNCT06258642
Small Cell Lung...
Irinotecan Lipo...
Anlotinib
18 Years - 75 YearsFudan University
Liposomal iRInotecan, Carboplatin or oXaliplatin for Esophagogastric CancerNCT03764553
Esophageal Canc...
Liposomal Irino...
Carboplatin
Capecitabine
Oxaliplatin
5-fluorouracil
Leucovorin
18 Years - Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
MM-398 and Ramucirumab in Treating Patients With Gastric Cancer or Gastroesophageal Junction AdenocarcinomaNCT03739801
Locally Advance...
Metastatic Gast...
Metastatic Unre...
Unresectable Ga...
Gastric Adenoca...
Gastroesophagea...
Liposomal Irino...
Quality-of-Life...
Questionnaire A...
Ramucirumab
18 Years - University of Southern California
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