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Spots Global Cancer Trial Database for dactinomycin

Every month we try and update this database with for dactinomycin cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.

Study titleNCT IDConditionsInterventionsEligibilityOrganizationLink
Combination Chemotherapy With or Without Temsirolimus in Treating Patients With Intermediate Risk RhabdomyosarcomaNCT02567435
Alveolar Rhabdo...
Botryoid-Type E...
Embryonal Rhabd...
Rhabdomyosarcom...
Sclerosing Rhab...
Spindle Cell Rh...
Cyclophosphamid...
Dactinomycin
Irinotecan Hydr...
Laboratory Biom...
Questionnaire A...
Radiation Thera...
Temsirolimus
Vincristine Sul...
Vinorelbine
- 40 YearsNational Cancer Institute (NCI)
Surgery and/or Chemotherapy in Treating Children With Infantile, Congenital, or Childhood FibrosarcomaNCT00072280
Sarcoma
dactinomycin
cyclophosphamid...
etoposide
ifosfamide
vincristine sul...
Conventional Su...
MESNA (mercapto...
Filgrastim
- 2 YearsChildren's Oncology Group
A Study Using Risk Factors to Determine Treatment for Children With Favorable Histology Wilms Tumors (FHWT)NCT06401330
Stage I Kidney ...
Stage II Kidney...
Stage III Kidne...
Stage IV Kidney...
Bone Scan
Carboplatin
Computed Tomogr...
Cyclophosphamid...
Dactinomycin
Doxorubicin
Etoposide
Irinotecan
Magnetic Resona...
Nephrectomy
Patient Observa...
Positron Emissi...
Ultrasound Imag...
Vincristine
X-Ray Imaging
- 30 YearsChildren's Oncology Group
Dactinomycin in Treating Patients With Persistent or Recurrent Gestational Trophoblastic NeoplasiaNCT00003688
Gestational Tro...
dactinomycin
12 Years - 50 YearsGOG Foundation
Chemotherapy With or Without Surgery, Radiation Therapy, or Stem Cell Transplantation in Treating Young Patients With Kidney TumorsNCT00002610
Kidney Cancer
dactinomycin
filgrastim
carboplatin
cyclophosphamid...
doxorubicin hyd...
etoposide
vincristine sul...
conventional su...
radiation thera...
- 21 YearsChildren's Oncology Group
Chemotherapy Before and After Surgery in Treating Children With Wilm's TumorNCT00047138
Kidney Cancer
dactinomycin
carboplatin
cyclophosphamid...
doxorubicin hyd...
etoposide
vincristine sul...
adjuvant therap...
conventional su...
neoadjuvant the...
radiation thera...
- 18 YearsNational Cancer Institute (NCI)
Combination Chemotherapy With or Without Radiation Therapy in Treating Young Patients With Newly Diagnosed Stage III or Stage IV Wilms' TumorNCT00379340
Stage III Kidne...
Stage IV Kidney...
3-Dimensional C...
Conventional Su...
Cyclophosphamid...
Dactinomycin
Doxorubicin Hyd...
Etoposide
Vincristine Sul...
- 29 YearsChildren's Oncology Group
Dactinomycin or Methotrexate in Treating Patients With Low-Risk Gestational Trophoblastic NeoplasiaNCT01535053
Choriocarcinoma
FIGO Stage I Ge...
FIGO Stage II G...
FIGO Stage III ...
Hydatidiform Mo...
Dactinomycin
Leucovorin Calc...
Methotrexate
Quality-of-Life...
18 Years - GOG Foundation
Intercontinental Multidisciplinary Registry and Treatment Optimization Study for Choroid Plexus TumorsNCT01014767
Brain Cancer
Choroid Plexus ...
Carboplatin
Cisplatin
Cyclophosphamid...
Dactinomycin
Doxorubicin
Etoposide
Irinotecan
Leucovorin
Methotrexate
Temozolomide
Vincristine
- Tufts Medical Center
Vincristine, Dactinomycin, and Doxorubicin With or Without Radiation Therapy or Observation Only in Treating Younger Patients Who Are Undergoing Surgery for Newly Diagnosed Stage I, Stage II, or Stage III Wilms' TumorNCT00352534
Stage I Kidney ...
Stage II Kidney...
Stage III Kidne...
3-Dimensional C...
Biospecimen Col...
Chest Radiograp...
Computed Tomogr...
Dactinomycin
Doxorubicin Hyd...
Echocardiograph...
Magnetic Resona...
Therapeutic Con...
Ultrasound Imag...
Vincristine Sul...
- 29 YearsChildren's Oncology Group
Chemotherapy With or Without Surgery, Radiation Therapy, or Stem Cell Transplantation in Treating Young Patients With Kidney TumorsNCT00002610
Kidney Cancer
dactinomycin
filgrastim
carboplatin
cyclophosphamid...
doxorubicin hyd...
etoposide
vincristine sul...
conventional su...
radiation thera...
- 21 YearsChildren's Oncology Group
International Pleuropulmonary Blastoma (PPB) Treatment and Biology RegistryNCT01464606
Pleuropulmonary...
Vincristine
Dactinomycin
Cyclophosphamid...
Ifosfamide
Doxorubicin
- 21 YearsChildren's Hospitals and Clinics of Minnesota
Combination Chemotherapy With or Without Radiation Therapy in Treating Young Patients With Newly Diagnosed Stage III or Stage IV Wilms' TumorNCT00379340
Stage III Kidne...
Stage IV Kidney...
3-Dimensional C...
Conventional Su...
Cyclophosphamid...
Dactinomycin
Doxorubicin Hyd...
Etoposide
Vincristine Sul...
- 29 YearsChildren's Oncology Group
Combination Chemotherapy With or Without Radiation Therapy in Treating Patients With Newly Diagnosed RhabdomyosarcomaNCT00002995
Sarcoma
dactinomycin
filgrastim
sargramostim
cyclophosphamid...
vincristine sul...
radiation thera...
- 49 YearsChildren's Oncology Group
Intercontinental Multidisciplinary Registry and Treatment Optimization Study for Choroid Plexus TumorsNCT01014767
Brain Cancer
Choroid Plexus ...
Carboplatin
Cisplatin
Cyclophosphamid...
Dactinomycin
Doxorubicin
Etoposide
Irinotecan
Leucovorin
Methotrexate
Temozolomide
Vincristine
- Tufts Medical Center
Combination Chemotherapy in Treating Children With Non-testicular Malignant Germ Cell TumorsNCT00002489
Extragonadal Ge...
Ovarian Cancer
dactinomycin
filgrastim
carboplatin
cyclophosphamid...
doxorubicin hyd...
etoposide
leucovorin calc...
methotrexate
vincristine sul...
conventional su...
- 20 YearsMemorial Sloan Kettering Cancer Center
Chemotherapy Before and After Surgery in Treating Children With Wilm's TumorNCT00047138
Kidney Cancer
dactinomycin
carboplatin
cyclophosphamid...
doxorubicin hyd...
etoposide
vincristine sul...
adjuvant therap...
conventional su...
neoadjuvant the...
radiation thera...
- 18 YearsNational Cancer Institute (NCI)
Biweekly Actinomycin-D Treatment or Multi-day Methotrexate Protocol in Low-risk Gestational Trophoblastic NeoplasiaNCT04562558
Gestational Tro...
Gestational Tro...
Stage I Gestati...
Stage II Gestat...
Stage III Gesta...
Invasive Mole
Choriocarcinoma
Methotrexate
Leucovorin
Dactinomycin
18 Years - 75 YearsPeking Union Medical College Hospital
Combination Chemotherapy With or Without Temsirolimus in Treating Patients With Intermediate Risk RhabdomyosarcomaNCT02567435
Alveolar Rhabdo...
Botryoid-Type E...
Embryonal Rhabd...
Rhabdomyosarcom...
Sclerosing Rhab...
Spindle Cell Rh...
Cyclophosphamid...
Dactinomycin
Irinotecan Hydr...
Laboratory Biom...
Questionnaire A...
Radiation Thera...
Temsirolimus
Vincristine Sul...
Vinorelbine
- 40 YearsNational Cancer Institute (NCI)
Chemotherapy Followed by Surgery and Radiation Therapy With or Without Stem Cell Transplant in Treating Patients With Relapsed or Refractory Wilms' Tumor or Clear Cell Sarcoma of the KidneyNCT00025103
Kidney Cancer
dactinomycin
carboplatin
cyclophosphamid...
doxorubicin hyd...
etoposide
melphalan
vincristine sul...
autologous bone...
conventional su...
peripheral bloo...
radiation thera...
- 17 YearsNational Cancer Institute (NCI)
Intercontinental Multidisciplinary Registry and Treatment Optimization Study for Choroid Plexus TumorsNCT01014767
Brain Cancer
Choroid Plexus ...
Carboplatin
Cisplatin
Cyclophosphamid...
Dactinomycin
Doxorubicin
Etoposide
Irinotecan
Leucovorin
Methotrexate
Temozolomide
Vincristine
- Tufts Medical Center
Combination Chemotherapy Alone or With Radiation Therapy in Treating Children With Kidney CancerNCT00002611
Kidney Cancer
dactinomycin
filgrastim
cyclophosphamid...
doxorubicin hyd...
etoposide
vincristine sul...
conventional su...
radiation thera...
0 Years - 15 YearsChildren's Oncology Group
Combination Chemotherapy With or Without Radiation Therapy in Treating Patients With Newly Diagnosed RhabdomyosarcomaNCT00002995
Sarcoma
dactinomycin
filgrastim
sargramostim
cyclophosphamid...
vincristine sul...
radiation thera...
- 49 YearsChildren's Oncology Group
Combination Chemotherapy in Treating Young Patients With Nonmetastatic RhabdomyosarcomaNCT00379457
Sarcoma
dactinomycin
carboplatin
cyclophosphamid...
doxorubicin hyd...
etoposide
ifosfamide
topotecan hydro...
vincristine sul...
vinorelbine tar...
conventional su...
radiation thera...
- 20 YearsNational Cancer Institute (NCI)
Addition of Ipilimumab (MDX-010) To Isolated Limb Infusion (ILI) With Standard Melphalan and Dactinomycin In The Treatment of Advanced Unresectable Melanoma of The ExtremityNCT01323517
Melanoma
Ipilimumab, Mel...
18 Years - Memorial Sloan Kettering Cancer Center
Vincristine, Dactinomycin, and Cyclophosphamide With or Without Radiation Therapy in Treating Patients With Embryonal RhabdomyosarcomaNCT00245141
Sarcoma
dactinomycin
cyclophosphamid...
vincristine sul...
radiation thera...
- 17 YearsNational Cancer Institute (NCI)
Combination Chemotherapy in Treating Children With Non-testicular Malignant Germ Cell TumorsNCT00002489
Extragonadal Ge...
Ovarian Cancer
dactinomycin
filgrastim
carboplatin
cyclophosphamid...
doxorubicin hyd...
etoposide
leucovorin calc...
methotrexate
vincristine sul...
conventional su...
- 20 YearsMemorial Sloan Kettering Cancer Center
Vincristine, Dactinomycin, and Cyclophosphamide in Treating Patients With Embryonal RhabdomyosarcomaNCT00245089
Sarcoma
dactinomycin
cyclophosphamid...
vincristine sul...
- 17 YearsNational Cancer Institute (NCI)
Combination Chemotherapy and Surgery in Treating Young Patients With Wilms TumorNCT00945009
Adult Kidney Wi...
Beckwith-Wiedem...
Childhood Kidne...
Diffuse Hyperpl...
Rhabdoid Tumor ...
Stage I Kidney ...
Stage II Kidney...
Stage III Kidne...
Stage IV Kidney...
Stage V Kidney ...
Dactinomycin
Doxorubicin Hyd...
Radiation Thera...
Therapeutic Con...
Vincristine Sul...
- 29 YearsChildren's Oncology Group
International Pleuropulmonary Blastoma (PPB) Treatment and Biology RegistryNCT01464606
Pleuropulmonary...
Vincristine
Dactinomycin
Cyclophosphamid...
Ifosfamide
Doxorubicin
- 21 YearsChildren's Hospitals and Clinics of Minnesota
Biweekly Actinomycin-D Treatment or Multi-day Methotrexate Protocol in Low-risk Gestational Trophoblastic NeoplasiaNCT04562558
Gestational Tro...
Gestational Tro...
Stage I Gestati...
Stage II Gestat...
Stage III Gesta...
Invasive Mole
Choriocarcinoma
Methotrexate
Leucovorin
Dactinomycin
18 Years - 75 YearsPeking Union Medical College Hospital
Comparison of Two Combination Chemotherapy Regimens in Treating Adults With Previously Untreated Leukemia or LymphomaNCT00002766
Leukemia
Lymphoma
dactinomycin
sargramostim
carmustine
cyclophosphamid...
cytarabine
daunorubicin hy...
doxorubicin hyd...
etoposide
mercaptopurine
methotrexate
mitoxantrone hy...
pegaspargase
prednisone
vincristine sul...
radiation thera...
18 Years - 120 YearsMemorial Sloan Kettering Cancer Center
Chemotherapy Plus Surgery in Treating Children at Risk of or With Stage I Wilms' TumorNCT00003804
Kidney Cancer
dactinomycin
vincristine sul...
conventional su...
- 17 YearsNational Cancer Institute (NCI)
Risk-Adapted Focal Proton Beam Radiation and/or Surgery in Patients With Low, Intermediate and High Risk Rhabdomyosarcoma Receiving Standard or Intensified ChemotherapyNCT01871766
Rhabdomyosarcom...
Vincristine
Dactinomycin
Cyclophosphamid...
Surgical Resect...
Radiation
Bevacizumab
Sorafenib
Myeloid Growth ...
Lymph Node Samp...
Irinotecan
Ifosfamide
Etoposide
Etoposide Phosp...
Doxorubicin
Dexrazoxane
^1^1C-methionin...
- 21 YearsSt. Jude Children's Research Hospital
Combination Chemotherapy Alone or With Radiation Therapy in Treating Children With Kidney CancerNCT00002611
Kidney Cancer
dactinomycin
filgrastim
cyclophosphamid...
doxorubicin hyd...
etoposide
vincristine sul...
conventional su...
radiation thera...
0 Years - 15 YearsChildren's Oncology Group
A Study Using Risk Factors to Determine Treatment for Children With Favorable Histology Wilms Tumors (FHWT)NCT06401330
Stage I Kidney ...
Stage II Kidney...
Stage III Kidne...
Stage IV Kidney...
Bone Scan
Carboplatin
Computed Tomogr...
Cyclophosphamid...
Dactinomycin
Doxorubicin
Etoposide
Irinotecan
Magnetic Resona...
Nephrectomy
Patient Observa...
Positron Emissi...
Ultrasound Imag...
Vincristine
X-Ray Imaging
- 30 YearsChildren's Oncology Group
Combination Chemotherapy, Radiation Therapy, and/or Surgery in Treating Patients With High-Risk Kidney TumorsNCT00335556
Childhood Renal...
Clear Cell Rena...
Clear Cell Sarc...
Papillary Renal...
Rhabdoid Tumor ...
Stage I Renal C...
Stage I Renal W...
Stage II Renal ...
Stage II Renal ...
Stage III Renal...
Stage III Renal...
Stage IV Renal ...
Stage IV Renal ...
Doxorubicin Hyd...
Irinotecan Hydr...
Conventional Su...
Cyclophosphamid...
Etoposide
Carboplatin
Dactinomycin
Vincristine Sul...
Radiation Thera...
Laboratory Biom...
- 29 YearsChildren's Oncology Group
Vincristine, Dactinomycin, and Cyclophosphamide With or Without Radiation Therapy in Treating Patients With Embryonal RhabdomyosarcomaNCT00245141
Sarcoma
dactinomycin
cyclophosphamid...
vincristine sul...
radiation thera...
- 17 YearsNational Cancer Institute (NCI)
A Study of Pembrolizumab Plus Local Chemotherapy Using Isolated Limb Infusion (ILI) for Patients With Sarcoma in the Arm or LegNCT04332874
Sarcoma
Myxofibrosarcom...
Undifferentiate...
Alveolar Soft P...
Isolated Limb I...
Pembrolizumab
infusion of mel...
12 Years - Memorial Sloan Kettering Cancer Center
Vincristine, Dactinomycin, and Cyclophosphamide in Treating Patients With Embryonal RhabdomyosarcomaNCT00245089
Sarcoma
dactinomycin
cyclophosphamid...
vincristine sul...
- 17 YearsNational Cancer Institute (NCI)
Chemotherapy Plus Surgery in Treating Children at Risk of or With Stage I Wilms' TumorNCT00003804
Kidney Cancer
dactinomycin
vincristine sul...
conventional su...
- 17 YearsNational Cancer Institute (NCI)
Treatment of Newly Diagnosed Rhabdomyosarcoma Using Molecular Risk Stratification and Liposomal Irinotecan Based Therapy in Children With Intermediate and High Risk DiseaseNCT06023641
Rhabdomyosarcom...
Vincristine
Dactinomycin
Cyclophosphamid...
Surgical Resect...
Proton beam rad...
Liposomal irino...
Vinorelbine
Temozolomide
Filgrastim, peg...
- 22 YearsSt. Jude Children's Research Hospital
Vincristine, Dactinomycin, and Cyclophosphamide With or Without Radiation Therapy in Treating Patients With Newly Diagnosed Low-Risk RhabdomyosarcomaNCT00075582
Adult Rhabdomyo...
Embryonal Child...
Embryonal-botry...
Previously Untr...
conventional su...
dactinomycin
cyclophosphamid...
vincristine sul...
radiation thera...
- 49 YearsChildren's Oncology Group
Combination Chemotherapy in Treating Patients With Previously Untreated RhabdomyosarcomaNCT00003958
Adult Malignant...
Adult Rhabdomyo...
Alveolar Childh...
Childhood Malig...
Embryonal Child...
Embryonal-botry...
Nonmetastatic C...
Previously Untr...
Stage I Adult S...
Stage II Adult ...
Stage III Adult...
dactinomycin
vincristine sul...
cyclophosphamid...
therapeutic con...
radiation thera...
topotecan hydro...
filgrastim
sargramostim
laboratory biom...
- 49 YearsChildren's Oncology Group
GAMEC-II, Risk-adapted Protocol for Relapsed Germ Cell Tumours (GCT)NCT06309732
Testicular Neop...
Pegfilgrastim
Dactinomycin
Methotrexate
Etoposide
Cisplatin
Epirubicin
16 Years - 35 YearsQueen Mary University of London
Combination Chemotherapy and Radiation Therapy in Treating Patients With Newly Diagnosed RhabdomyosarcomaNCT00354835
Adult Rhabdomyo...
Childhood Alveo...
Childhood Botry...
Childhood Embry...
Localized Child...
Rhabdomyosarcom...
Sarcoma
Stage I Adult S...
Stage II Adult ...
Stage III Adult...
Cyclophosphamid...
Dactinomycin
Irinotecan Hydr...
Laboratory Biom...
Questionnaire A...
Radiation Thera...
Vincristine Sul...
- 49 YearsChildren's Oncology Group
High-Dose Combination Chemotherapy and Radiation Therapy in Treating Patients With Newly Diagnosed Metastatic Rhabdomyosarcoma or EctomesenchymomaNCT00354744
Sarcoma
dactinomycin
cyclophosphamid...
doxorubicin hyd...
etoposide
ifosfamide
irinotecan hydr...
vincristine sul...
conventional su...
radiation thera...
filgrastim
- 49 YearsChildren's Oncology Group
High-Dose Combination Chemotherapy and Radiation Therapy in Treating Patients With Newly Diagnosed Metastatic Rhabdomyosarcoma or EctomesenchymomaNCT00354744
Sarcoma
dactinomycin
cyclophosphamid...
doxorubicin hyd...
etoposide
ifosfamide
irinotecan hydr...
vincristine sul...
conventional su...
radiation thera...
filgrastim
- 49 YearsChildren's Oncology Group
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