Spots Global Cancer Trial Database for patient observation

Every month we try and update this database with for patient observation cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization
Testing Immunotherapy Versus Observation in Patients With HPV Throat Cancer	NCT03811015	Clinical Stage ... Clinical Stage ... Pathologic Stag... Pathologic Stag...	Biospecimen Col... Cisplatin Computed Tomogr... Echocardiograph... Fludeoxyglucose... Intensity-Modul... Nivolumab Patient Observa... Positron Emissi...	18 Years -	National Cancer Institute (NCI)
Nivolumab in Treating Patients With Localized Kidney Cancer Undergoing Nephrectomy	NCT03055013	Metastatic Rena... Sarcomatoid Ren... Stage II Renal ... Stage III Renal... Unclassified Re...	Nephrectomy Nivolumab Patient Observa...	18 Years -	National Cancer Institute (NCI)
A Study Using Risk Factors to Determine Treatment for Children With Favorable Histology Wilms Tumors (FHWT)	NCT06401330	Stage I Kidney ... Stage II Kidney... Stage III Kidne... Stage IV Kidney...	Bone Scan Carboplatin Computed Tomogr... Cyclophosphamid... Dactinomycin Doxorubicin Etoposide Irinotecan Magnetic Resona... Nephrectomy Patient Observa... Positron Emissi... Ultrasound Imag... Vincristine X-Ray Imaging	- 30 Years	Children's Oncology Group
Nivolumab After Combined Modality Therapy in Treating Patients With High Risk Stage II-IIIB Anal Cancer	NCT03233711	Anal Basaloid S... Anal Canal Cloa... Anal Margin Squ... Stage IIB Anal ... Stage III Anal ...	Biopsy Biospecimen Col... Colonoscopy Computed Tomogr... Digital Rectal ... High Resolution... Magnetic Resona... Nivolumab Patient Observa... Proctoscopy Sigmoidoscopy X-Ray Imaging	18 Years -	National Cancer Institute (NCI)
Testing the Use of BRAF-Targeted Therapy After Surgery and Usual Chemotherapy for BRAF-Mutated Colon Cancer	NCT05710406	Colon Adenocarc... Microsatellite ... Stage IIB Colon... Stage IIC Colon... Stage III Colon...	Encorafenib Cetuximab Biospecimen Col... Computed Tomogr... Magnetic Resona... Patient Observa...	18 Years -	Alliance for Clinical Trials in Oncology
CPAP in Treating Obstructive Sleep Apnea in Patients With Polycythemia Vera or Essential Thrombocythemia	NCT03972943	CALR Gene Mutat... Essential Throm... JAK2 Gene Mutat... MPL Gene Mutati... Obstructive Sle... Polycythemia Ve...	Continuous Posi... Patient Observa... Questionnaire A...	30 Years - 85 Years	University of Utah
Evaluating the Addition of the Immunotherapy Drug Atezolizumab to Standard Chemotherapy Treatment for Advanced or Metastatic Neuroendocrine Carcinomas That Originate Outside the Lung	NCT05058651	Advanced Extrap... Metastatic Extr... Recurrent Extra... Unresectable Ex...	Atezolizumab Biospecimen Col... Carboplatin Cisplatin Computed Tomogr... Etoposide Magnetic Resona... Patient Observa...	18 Years -	National Cancer Institute (NCI)
Nivolumab in Treating Patients With Localized Kidney Cancer Undergoing Nephrectomy	NCT03055013	Metastatic Rena... Sarcomatoid Ren... Stage II Renal ... Stage III Renal... Unclassified Re...	Nephrectomy Nivolumab Patient Observa...	18 Years -	National Cancer Institute (NCI)
Testing Drug Treatments After CAR T-cell Therapy in Patients With Relapsed/Refractory Diffuse Large B-cell Lymphoma	NCT05633615	Diffuse Large B... Grade 3b Follic... Primary Mediast... Recurrent Diffu... Refractory Diff... Transformed Fol... Transformed Mar...	Axicabtagene Ci... Biospecimen Col... Computed Tomogr... Cyclophosphamid... Fludarabine Lisocabtagene M... Mosunetuzumab Patient Observa... Polatuzumab Ved... Positron Emissi... Tisagenlecleuce...	18 Years -	SWOG Cancer Research Network
Study of Mucosal Sparing Adjuvant Radiotherapy After Surgical Exploration in HPV+ Head and Neck Cancer of Unknown Primaries	NCT04489212	Clinical Stage ... Clinical Stage ... Clinical Stage ... Head and Neck C... Pathologic Stag... Pathologic Stag...	Medical Chart R... Patient Observa... Quality-of-Life... Questionnaire A...	18 Years -	Mayo Clinic
Cisplatin and Combination Chemotherapy in Treating Children and Young Adults With Hepatoblastoma or Liver Cancer After Surgery	NCT03533582	Childhood Hepat... Childhood Malig... Fibrolamellar C... Hepatoblastoma Hepatocellular ...	Carboplatin Cisplatin Doxorubicin Etoposide Fluorouracil Gemcitabine Irinotecan Laboratory Biom... Oxaliplatin Patient Observa... Resection Sorafenib Vincristine Sul...	- 30 Years	Children's Oncology Group
Epcoritamab Compared to Observation for Treating B-cell Lymphoma Patients Not in Complete Remission After CD19-directed CAR-T Therapy	NCT06238648	Diffuse Large B... Primary Mediast... Transformed Ind...	Biopsy Biospecimen Col... Computed Tomogr... Epcoritamab Magnetic Resona... Patient Observa... Positron Emissi...	18 Years -	Academic and Community Cancer Research United
Testing the Use of BRAF-Targeted Therapy After Surgery and Usual Chemotherapy for BRAF-Mutated Colon Cancer	NCT05710406	Colon Adenocarc... Microsatellite ... Stage IIB Colon... Stage IIC Colon... Stage III Colon...	Encorafenib Cetuximab Biospecimen Col... Computed Tomogr... Magnetic Resona... Patient Observa...	18 Years -	Alliance for Clinical Trials in Oncology
Testing MK-3475 (Pembrolizumab) as Adjuvant Therapy for Triple Receptor-Negative Breast Cancer	NCT02954874	Invasive Breast... Stage 0 Breast ... Stage I Breast ... Stage II Breast... Stage III Breas... Triple-Negative...	Biospecimen Col... Laboratory Biom... Patient Observa... Pembrolizumab Quality-of-Life... Questionnaire A... Radiation Thera...	18 Years -	National Cancer Institute (NCI)
CPAP in Treating Obstructive Sleep Apnea in Patients With Polycythemia Vera or Essential Thrombocythemia	NCT03972943	CALR Gene Mutat... Essential Throm... JAK2 Gene Mutat... MPL Gene Mutati... Obstructive Sle... Polycythemia Ve...	Continuous Posi... Patient Observa... Questionnaire A...	30 Years - 85 Years	University of Utah
Pembrolizumab in Treating Patients With High Risk Oral Intraepithelial Neoplasia	NCT02882282	Oral Cavity Car... Oral Intraepith...	Laboratory Biom... Patient Observa... Pembrolizumab	18 Years -	M.D. Anderson Cancer Center
Stereotactic Body Radiation Therapy Plus Androgen Receptor Pathway Inhibitor and Androgen Deprivation Therapy for Treatment of Metastatic, Recurrent Hormone-Sensitive Prostate Cancer, DIVINE Trial	NCT06378866	Recurrent Castr... Stage IVB Prost... Recurrent Prost... Castration-resi...	Abiraterone Apalutamide Biospecimen Col... Bone Scan Computed Tomogr... Darolutamide Degarelix Enzalutamide Goserelin Histrelin Leuprolide Magnetic Resona... Patient Observa... Positron Emissi... Prednisone Questionnaire A... Relugolix Stereotactic Bo... Triptorelin	18 Years -	Mayo Clinic
Nivolumab or Expectant Observation Following Ipilimumab, Nivolumab, and Surgery in Treating Patients With High Risk Localized, Locoregionally Advanced, or Recurrent Mucosal Melanoma	NCT03220009	Cervical Carcin... Esophageal Carc... Mucosal Melanom... Mucosal Melanom... Oral Cavity Muc... Recurrent Melan... Stage II Vulvar... Stage III Vulva... Stage IIIA Vulv... Stage IIIB Vulv... Stage IIIC Vulv... Stage IV Oral C... Stage IV Vulvar... Stage IVA Oral ... Stage IVB Oral ... Stage IVC Oral ... Vaginal Carcino...	Conventional Su... Ipilimumab Laboratory Biom... Nivolumab Patient Observa... Radiation Thera...	18 Years -	National Cancer Institute (NCI)
A Study Using Risk Factors to Determine Treatment for Children With Favorable Histology Wilms Tumors (FHWT)	NCT06401330	Stage I Kidney ... Stage II Kidney... Stage III Kidne... Stage IV Kidney...	Bone Scan Carboplatin Computed Tomogr... Cyclophosphamid... Dactinomycin Doxorubicin Etoposide Irinotecan Magnetic Resona... Nephrectomy Patient Observa... Positron Emissi... Ultrasound Imag... Vincristine X-Ray Imaging	- 30 Years	Children's Oncology Group
Pembrolizumab vs. Observation in People With Triple-negative Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Pembrolizumab	NCT05812807	Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Early Stage Tri...	Pembrolizumab Patient Observa... Biopsy Biospecimen Col... Questionnaire A... Quality-of-Life...	18 Years -	Alliance for Clinical Trials in Oncology
Circulating Tumor DNA Testing in Predicting Treatment for Patients With Stage IIA Colon Cancer After Surgery	NCT04068103	Colon Adenocarc... Stage IIA Colon...	Capecitabine Fluorouracil Leucovorin Leucovorin Calc... Oxaliplatin Patient Observa...	18 Years -	NRG Oncology
CPAP in Treating Obstructive Sleep Apnea in Patients With Polycythemia Vera or Essential Thrombocythemia	NCT03972943	CALR Gene Mutat... Essential Throm... JAK2 Gene Mutat... MPL Gene Mutati... Obstructive Sle... Polycythemia Ve...	Continuous Posi... Patient Observa... Questionnaire A...	30 Years - 85 Years	University of Utah
Using Biomarkers to Help Guide Safe Immunotherapy Discontinuation in Patients With Unresectable Stage IIIB-IV Melanoma, The PET-Stop Trial	NCT04462406	Advanced Melano... Clinical Stage ... Clinical Stage ... Melanoma of Unk... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Unresectable Ac... Unresectable Me... Unresectable Mu...	Ipilimumab Nivolumab Patient Observa... Pembrolizumab	18 Years -	Eastern Cooperative Oncology Group
Active Surveillance and Chemotherapy Before Surgery in Treating Participants With Stage II-III Rectal Cancer	NCT03594630	Rectal Adenocar... Stage II Rectal... Stage IIA Recta... Stage IIB Recta... Stage IIC Recta... Stage III Recta... Stage IIIA Rect... Stage IIIB Rect... Stage IIIC Rect...	Chemotherapy Patient Observa... Questionnaire A... Resection of Re...	18 Years -	M.D. Anderson Cancer Center
Using Biomarkers to Help Guide Safe Immunotherapy Discontinuation in Patients With Unresectable Stage IIIB-IV Melanoma, The PET-Stop Trial	NCT04462406	Advanced Melano... Clinical Stage ... Clinical Stage ... Melanoma of Unk... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Unresectable Ac... Unresectable Me... Unresectable Mu...	Ipilimumab Nivolumab Patient Observa... Pembrolizumab	18 Years -	Eastern Cooperative Oncology Group
Testing Immunotherapy Versus Observation in Patients With HPV Throat Cancer	NCT03811015	Clinical Stage ... Clinical Stage ... Pathologic Stag... Pathologic Stag...	Biospecimen Col... Cisplatin Computed Tomogr... Echocardiograph... Fludeoxyglucose... Intensity-Modul... Nivolumab Patient Observa... Positron Emissi...	18 Years -	National Cancer Institute (NCI)
Circulating Tumor DNA Testing in Predicting Treatment for Patients With Stage IIA Colon Cancer After Surgery	NCT04068103	Colon Adenocarc... Stage IIA Colon...	Capecitabine Fluorouracil Leucovorin Leucovorin Calc... Oxaliplatin Patient Observa...	18 Years -	NRG Oncology

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