Spots Global Cancer Trial Database for stage iii rectal cancer ajcc v8

Every month we try and update this database with for stage iii rectal cancer ajcc v8 cancer trials from around the world to help patients and their families find trials that might be right for them.
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The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization
Panitumumab, Regorafenib, or TAS-102, in Treating Patients With Metastatic and/or Unresectable RAS Wild-Type Colorectal Cancer	NCT03992456	Metastatic Colo... Metastatic Colo... Metastatic Rect... Stage III Colon... Stage III Color... Stage III Recta... Stage IIIA Colo... Stage IIIA Colo... Stage IIIA Rect... Stage IIIB Colo... Stage IIIB Colo... Stage IIIB Rect... Stage IIIC Colo... Stage IIIC Colo... Stage IIIC Rect... Stage IV Colon ... Stage IV Colore... Stage IV Rectal... Stage IVA Colon... Stage IVA Color... Stage IVA Recta... Stage IVB Colon... Stage IVB Color... Stage IVB Recta... Stage IVC Colon... Stage IVC Color... Stage IVC Recta... Unresectable Co... Unresectable Co... Unresectable Re...	Panitumumab Quality-of-Life... Questionnaire A... Regorafenib Trifluridine an...	18 Years -	Academic and Community Cancer Research United
Short Course Radiation Therapy and Combination Chemotherapy for the Treatment of Stage II-III Rectal Cancer	NCT04703101	Locally Advance... Rectal Adenocar... Stage II Rectal... Stage IIA Recta... Stage IIB Recta... Stage IIC Recta... Stage III Recta... Stage IIIA Rect... Stage IIIB Rect... Stage IIIC Rect...	Capecitabine Fluorouracil Intensity-Modul... Leucovorin Oxaliplatin Quality-of-Life... Surveillance Total Mesorecta...	18 Years -	Jonsson Comprehensive Cancer Center
Genetic Testing in Screening Patients With Metastatic or Unresectable Colon or Rectal Cancer for a COLOMATE Trial	NCT03765736	Metastatic Colo... Metastatic Rect... Stage III Colon... Stage III Recta... Stage IIIA Colo... Stage IIIA Rect... Stage IIIB Colo... Stage IIIB Rect... Stage IIIC Colo... Stage IIIC Rect... Stage IV Colon ... Stage IV Rectal... Stage IVA Colon... Stage IVA Recta... Stage IVB Colon... Stage IVB Recta... Stage IVC Colon... Stage IVC Recta... Unresectable Co... Unresectable Re...	Genetic Testing	18 Years -	Academic and Community Cancer Research United
Testing the Addition of an Anti-Cancer Drug, Irinotecan, to the Standard Chemotherapy Treatment (FOLFOX) After Long-Course Radiation Therapy for Advanced-Stage Rectal Cancers to Improve the Rate of Complete Response and Long-Term Rates of Organ Preservation	NCT05610163	Locally Advance... Stage II Rectal... Stage III Recta...	Capecitabine 5-fluorouracil Leucovorin calc... Irinotecan Oxaliplatin Long Course Che... Computed Tomogr... Magnetic Resona... Sigmoidoscopy biopsy	18 Years -	Alliance for Clinical Trials in Oncology
Regorafenib, Ipilimumab and Nivolumab for the Treatment of Chemotherapy Resistant Microsatellite Stable Metastatic Colorectal Cancer	NCT04362839	Advanced Colon ... Metastatic Colo... Metastatic Colo... Metastatic Colo... Metastatic Rect... Stage III Colon... Stage III Recta... Stage IIIA Colo... Stage IIIA Rect... Stage IIIB Colo... Stage IIIB Rect... Stage IIIC Colo... Stage IIIC Rect... Stage IV Colon ... Stage IV Colore... Stage IV Rectal... Stage IVA Colon... Stage IVA Color... Stage IVA Recta... Stage IVB Colon... Stage IVB Color... Stage IVB Recta... Stage IVC Colon... Stage IVC Color... Stage IVC Recta...	Ipilimumab Nivolumab Regorafenib	18 Years -	City of Hope Medical Center
Testing the Addition of a Radiation Sensitizing Drug, IPdR, to the Usual Chemotherapy Treatment (Capecitabine) During Radiation Therapy for Rectal Cancer	NCT04406857	Locally Advance... Rectal Adenocar... Stage II Rectal... Stage III Recta...	Capecitabine Radiation Thera... Ropidoxuridine	18 Years -	National Cancer Institute (NCI)
Testing the Addition of a Radiation Sensitizing Drug, IPdR, to the Usual Chemotherapy Treatment (Capecitabine) During Radiation Therapy for Rectal Cancer	NCT04406857	Locally Advance... Rectal Adenocar... Stage II Rectal... Stage III Recta...	Capecitabine Radiation Thera... Ropidoxuridine	18 Years -	National Cancer Institute (NCI)
Testing the Addition of Nivolumab to Standard Treatment for Patients With Metastatic or Unresectable Colorectal Cancer That Have a BRAF Mutation	NCT05308446	Metastatic Colo... Metastatic Rect... Stage III Colon... Stage III Recta... Stage IV Colon ... Stage IV Rectal... Unresectable Co... Unresectable Re...	Cetuximab Encorafenib Nivolumab	18 Years -	National Cancer Institute (NCI)
TAS-102 With Concurrent Radiation for the Treatment of Untreated Resectable Stage II-III Rectal Cancer	NCT04104139	Rectal Adenocar... Stage IIA Recta... Stage IIB Recta... Stage III Recta... Stage IIIA Rect... Stage IIIB Rect... Stage IIIC Rect...	3-Dimensional C... Intensity-Modul... Trifluridine an...	18 Years -	OHSU Knight Cancer Institute
Evaluation of Quality of Life and Utilities Following Surgical Treatment of Stage I-IV Rectal Cancer	NCT02107105	Rectal Adenocar... Stage I Rectal ... Stage II Rectal... Stage IIA Recta... Stage IIB Recta... Stage IIC Recta... Stage III Recta... Stage IIIA Rect... Stage IIIB Rect... Stage IIIC Rect... Stage IV Rectal... Stage IVA Recta... Stage IVB Recta... Stage IVC Recta...	Quality-of-Life... Questionnaire A...	18 Years -	M.D. Anderson Cancer Center
Therapy Adapted for High Risk and Low Risk HIV-Associated Anal Cancer	NCT04929028	AIDS-Related An... Anal Basaloid S... Anal Canal Cloa... Anal Margin Squ... Anal Squamous C... HIV Infection Rectal Squamous... Stage I Anal Ca... Stage II Anal C... Stage II Rectal... Stage III Anal ... Stage III Recta...	Capecitabine Fluorouracil Intensity-Modul... Mitomycin Nivolumab	18 Years -	National Cancer Institute (NCI)
Regorafenib, Ipilimumab and Nivolumab for the Treatment of Chemotherapy Resistant Microsatellite Stable Metastatic Colorectal Cancer	NCT04362839	Advanced Colon ... Metastatic Colo... Metastatic Colo... Metastatic Colo... Metastatic Rect... Stage III Colon... Stage III Recta... Stage IIIA Colo... Stage IIIA Rect... Stage IIIB Colo... Stage IIIB Rect... Stage IIIC Colo... Stage IIIC Rect... Stage IV Colon ... Stage IV Colore... Stage IV Rectal... Stage IVA Colon... Stage IVA Color... Stage IVA Recta... Stage IVB Colon... Stage IVB Color... Stage IVB Recta... Stage IVC Colon... Stage IVC Color... Stage IVC Recta...	Ipilimumab Nivolumab Regorafenib	18 Years -	City of Hope Medical Center
Short Course Radiation Therapy and Combination Chemotherapy for the Treatment of Stage II-III Rectal Cancer	NCT04703101	Locally Advance... Rectal Adenocar... Stage II Rectal... Stage IIA Recta... Stage IIB Recta... Stage IIC Recta... Stage III Recta... Stage IIIA Rect... Stage IIIB Rect... Stage IIIC Rect...	Capecitabine Fluorouracil Intensity-Modul... Leucovorin Oxaliplatin Quality-of-Life... Surveillance Total Mesorecta...	18 Years -	Jonsson Comprehensive Cancer Center
TAS-102 With Concurrent Radiation for the Treatment of Untreated Resectable Stage II-III Rectal Cancer	NCT04104139	Rectal Adenocar... Stage IIA Recta... Stage IIB Recta... Stage III Recta... Stage IIIA Rect... Stage IIIB Rect... Stage IIIC Rect...	3-Dimensional C... Intensity-Modul... Trifluridine an...	18 Years -	OHSU Knight Cancer Institute
Time-Restricted Eating Versus Nutritional Counseling for the Reduction of Radiation or Chemoradiation Tx Side Effects in Patients With Prostate, Cervical, or Rectal Cancers	NCT05722288	Localized Prost... Locally Advance... Locally Advance... Malignant Solid... Recurrent Prost... Stage I Prostat... Stage IB Cervic... Stage IB2 Cervi... Stage II Prosta... Stage II Rectal... Stage IIA Cervi... Stage IIB Cervi... Stage III Prost... Stage III Recta... Stage IIIA Cerv... Stage IIIB Cerv... Stage IIIC Cerv... Stage IVA Prost...	Biospecimen Col... Informational I... Quality-of-Life... Questionnaire A... Short-Term Fast...	18 Years -	City of Hope Medical Center
Circulating Tumor Cells in Patients With Locally Advanced Rectal Cancer	NCT02874885	Locally Advance... Metastatic Rect... Rectosigmoid Ad... Recurrent Recta... Recurrent Recto... Stage III Recta... Stage IIIA Rect... Stage IIIB Rect... Stage IIIC Rect... Stage IV Rectal... Stage IVA Recta... Stage IVB Recta... Stage IVC Recta...	Biospecimen Col...	18 Years -	M.D. Anderson Cancer Center
Testing Nivolumab and Ipilimumab With Short-Course Radiation in Locally Advanced Rectal Cancer	NCT04751370	Locally Advance... Stage II Rectal... Stage III Recta...	Computed Tomogr... Ipilimumab Magnetic Resona... Nivolumab Radiation Thera... Sigmoidoscopy Total Mesorecta...	18 Years -	National Cancer Institute (NCI)
Financial Burden Assessment in Patients With Stage I-III Colon or Rectal Cancer Undergoing Treatment	NCT03516942	Stage I Colon C... Stage I Rectal ... Stage II Colon ... Stage II Rectal... Stage IIA Colon... Stage IIA Recta... Stage IIB Colon... Stage IIB Recta... Stage IIC Colon... Stage IIC Recta... Stage III Colon... Stage III Recta... Stage IIIA Colo... Stage IIIA Rect... Stage IIIB Colo... Stage IIIB Rect... Stage IIIC Colo... Stage IIIC Rect...	Quality-of-Life... Questionnaire A...	18 Years -	Eastern Cooperative Oncology Group
Testing Nivolumab and Ipilimumab With Short-Course Radiation in Locally Advanced Rectal Cancer	NCT04751370	Locally Advance... Stage II Rectal... Stage III Recta...	Computed Tomogr... Ipilimumab Magnetic Resona... Nivolumab Radiation Thera... Sigmoidoscopy Total Mesorecta...	18 Years -	National Cancer Institute (NCI)
Genetic Testing in Screening Patients With Metastatic or Unresectable Colon or Rectal Cancer for a COLOMATE Trial	NCT03765736	Metastatic Colo... Metastatic Rect... Stage III Colon... Stage III Recta... Stage IIIA Colo... Stage IIIA Rect... Stage IIIB Colo... Stage IIIB Rect... Stage IIIC Colo... Stage IIIC Rect... Stage IV Colon ... Stage IV Rectal... Stage IVA Colon... Stage IVA Recta... Stage IVB Colon... Stage IVB Recta... Stage IVC Colon... Stage IVC Recta... Unresectable Co... Unresectable Re...	Genetic Testing	18 Years -	Academic and Community Cancer Research United
TAS-102, Irinotecan, and Bevacizumab for the Treatment of Pre-treated Metastatic or Unresectable Colorectal Cancer, the TABAsCO Study	NCT04109924	Advanced Colore... Metastatic Colo... Metastatic Rect... Recurrent Colon... Recurrent Color... Recurrent Recta... Stage III Colon... Stage III Color... Stage III Recta... Stage IIIA Colo... Stage IIIA Colo... Stage IIIB Colo... Stage IIIB Rect... Stage IIIC Colo... Stage IIIC Colo... Stage IV Colon ... Stage IVA Color... Stage IVA Recta... Stage IVB Colon... Stage IVB Color... Stage IVB Recta... Stage IVC Colon... Stage IVC Color... Stage IVC Recta... Unresectable Co... Unresectable Co... Unresectable Re...	Irinotecan Bevacizumab Trifluridine an...	18 Years -	Roswell Park Cancer Institute
Testing the Addition of Nivolumab to Standard Treatment for Patients With Metastatic or Unresectable Colorectal Cancer That Have a BRAF Mutation	NCT05308446	Metastatic Colo... Metastatic Rect... Stage III Colon... Stage III Recta... Stage IV Colon ... Stage IV Rectal... Unresectable Co... Unresectable Re...	Cetuximab Encorafenib Nivolumab	18 Years -	National Cancer Institute (NCI)
Short Course Radiation Therapy and Combination Chemotherapy for the Treatment of Stage II-III Rectal Cancer	NCT04703101	Locally Advance... Rectal Adenocar... Stage II Rectal... Stage IIA Recta... Stage IIB Recta... Stage IIC Recta... Stage III Recta... Stage IIIA Rect... Stage IIIB Rect... Stage IIIC Rect...	Capecitabine Fluorouracil Intensity-Modul... Leucovorin Oxaliplatin Quality-of-Life... Surveillance Total Mesorecta...	18 Years -	Jonsson Comprehensive Cancer Center
Active Surveillance and Chemotherapy Before Surgery in Treating Participants With Stage II-III Rectal Cancer	NCT03594630	Rectal Adenocar... Stage II Rectal... Stage IIA Recta... Stage IIB Recta... Stage IIC Recta... Stage III Recta... Stage IIIA Rect... Stage IIIB Rect... Stage IIIC Rect...	Chemotherapy Patient Observa... Questionnaire A... Resection of Re...	18 Years -	M.D. Anderson Cancer Center
Regorafenib, Ipilimumab and Nivolumab for the Treatment of Chemotherapy Resistant Microsatellite Stable Metastatic Colorectal Cancer	NCT04362839	Advanced Colon ... Metastatic Colo... Metastatic Colo... Metastatic Colo... Metastatic Rect... Stage III Colon... Stage III Recta... Stage IIIA Colo... Stage IIIA Rect... Stage IIIB Colo... Stage IIIB Rect... Stage IIIC Colo... Stage IIIC Rect... Stage IV Colon ... Stage IV Colore... Stage IV Rectal... Stage IVA Colon... Stage IVA Color... Stage IVA Recta... Stage IVB Colon... Stage IVB Color... Stage IVB Recta... Stage IVC Colon... Stage IVC Color... Stage IVC Recta...	Ipilimumab Nivolumab Regorafenib	18 Years -	City of Hope Medical Center
Testing the Addition of an Anti-Cancer Drug, Irinotecan, to the Standard Chemotherapy Treatment (FOLFOX) After Long-Course Radiation Therapy for Advanced-Stage Rectal Cancers to Improve the Rate of Complete Response and Long-Term Rates of Organ Preservation	NCT05610163	Locally Advance... Stage II Rectal... Stage III Recta...	Capecitabine 5-fluorouracil Leucovorin calc... Irinotecan Oxaliplatin Long Course Che... Computed Tomogr... Magnetic Resona... Sigmoidoscopy biopsy	18 Years -	Alliance for Clinical Trials in Oncology
Savolitinib in Treating Patients With MET Amplified Metastatic or Unresectable Colorectal Cancer	NCT03592641	Colorectal Carc... Metastatic Colo... Metastatic Rect... Stage III Colon... Stage III Recta... Stage IIIA Colo... Stage IIIA Rect... Stage IIIB Colo... Stage IIIB Rect... Stage IIIC Colo... Stage IIIC Rect... Stage IV Colon ... Stage IV Rectal... Stage IVA Colon... Stage IVA Recta... Stage IVB Colon... Stage IVB Recta... Stage IVC Colon... Stage IVC Recta... Unresectable Co... Unresectable Re...	Savolitinib	18 Years -	National Cancer Institute (NCI)

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