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Spots Global Cancer Trial Database for prophylactic cranial irradiation

Every month we try and update this database with for prophylactic cranial irradiation cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.

Study titleNCT IDConditionsInterventionsEligibilityOrganizationLink
PCI for Patients With ES-SCLC After RCT:a Prospective Randomized StudyNCT04535739
Small-cell Lung...
prophylactic cr...
18 Years - 65 YearsChineseAMS
Prophylactic Cranial Irradiation in Patients With Lung Adenocarcinoma With High Risk of Brain MetastasisNCT01603849
Lung Cancer
Prophylactic Cr...
18 Years - 60 YearsInstituto Nacional de Cancerologia de Mexico
Efficacy and Safety of Prophylactic Cranial Irradiation Versus MRI Surveillance in Patients With Limited-stage Small Cell Lung Cancer Who Achieved Remission After First-line ChemoradiotherapyNCT04829708
Limited Stage S...
MRI Surveillanc...
Prophylactic Cr...
18 Years - 75 YearsShandong Cancer Hospital and Institute
Prophylactic Cranial Irradiation in Extensive-stage Small Cell Lung CancerNCT04947774
Extensive-stage...
Prophylactic Cr...
18 Years - ChineseAMS
PRophylactic Cerebral Irradiation or Active MAgnetic Resonance Imaging Surveillance in Small-cell Lung Cancer Patients (PRIMALung Study)NCT04790253
Limited Stage S...
Extensive-stage...
Prophylactic cr...
18 Years - European Organisation for Research and Treatment of Cancer - EORTC
Prophylactic Cranial Irradiation (PCI) vs Observation in Stage III NSCLCNCT01282437
Non Small Cell ...
Radical Treatme...
Stage III Non-S...
Prophylactic Cr...
18 Years - Maastricht Radiation Oncology
PCI and Brain MRI Follow-up vs Brain MRI Follow-up Alone in Limited-stage SCLC PatientsNCT05651802
Small Cell Lung...
Prophylactic cr...
Thoracic radiot...
Chemotherapy
18 Years - Zhejiang Cancer Hospital
S1827 (MAVERICK) Testing Whether the Use of Brain Scans Alone Instead of Brain Scans Plus Preventive Brain Radiation Affects Lifespan in Patients With Small Cell Lung CancerNCT04155034
Extensive Stage...
Limited Stage L...
Lung Small Cell...
Magnetic Resona...
Prophylactic Cr...
18 Years - SWOG Cancer Research Network
Study of Whole-brain Irradiation With Chloroquine for Brain MetastasesNCT01894633
Brain Metastasi...
Chloroquine
Total brain rad...
46 Years - 61 YearsInstituto Nacional de Cancerologia de Mexico
Hippocampus Avoidance PCI vs PCINCT01780675
Small Cell Lung...
Lung Cancer
Radiation Proph...
Radiation Hippo...
18 Years - The Netherlands Cancer Institute
Prophylactic Cranial Irradiation (PCI) Versus no PCI in Non Small Cell Lung Cancer After a Response to ChemotherapyNCT00745797
Brain Metastase...
Radiotherapy
18 Years - 75 YearsChinese Society of Lung Cancer
Study of Whole-brain Irradiation With Chloroquine for Brain MetastasesNCT01894633
Brain Metastasi...
Chloroquine
Total brain rad...
46 Years - 61 YearsInstituto Nacional de Cancerologia de Mexico
Prophylactic Cranial Irradiation (PCI) Cognitive Tests in Non-small Cell Lung Cancer (NSCLC) PatientsNCT01290809
NSCLC
18 Years - Maastricht Radiation Oncology
Prophylactic Cranial Irradiation (PCI) for Small Cell Carcinoma of the UrotheliumNCT00756639
Bladder Cancer
Prophylactic Cr...
Brain X-ray
18 Years - M.D. Anderson Cancer Center
Pegaspargase and Combination Chemotherapy in Treating Younger Patients With Newly Diagnosed High-Risk Acute Lymphoblastic Leukemia (Closed to Accrual 4-22-2011)NCT00866307
Acute Lymphobla...
Adult B Acute L...
Childhood B Acu...
Cyclophosphamid...
Cytarabine
Daunorubicin Hy...
Dexamethasone
Doxorubicin Hyd...
Laboratory Biom...
Mercaptopurine
Methotrexate
Pegaspargase
Prednisone
Prophylactic Cr...
Thioguanine
Vincristine Sul...
1 Year - 30 YearsChildren's Oncology Group
Prophylactic Cranial Irradiation (PCI) for Small Cell Carcinoma of the UrotheliumNCT00756639
Bladder Cancer
Prophylactic Cr...
Brain X-ray
18 Years - M.D. Anderson Cancer Center
PCI for Patients With ES-SCLC After RCT:a Prospective Randomized StudyNCT04535739
Small-cell Lung...
prophylactic cr...
18 Years - 65 YearsChineseAMS
Combined Modality Treatment for Resectable Non-Small Cell Superior Sulcus TumorsNCT00984997
Lung Cancer
Surgery
Chest Irradiati...
Cisplatin
Etoposide
Prophylactic Cr...
18 Years - 70 YearsM.D. Anderson Cancer Center
Prophylactic Cranial Irradiation (PCI) for Small Cell Carcinoma of the UrotheliumNCT00756639
Bladder Cancer
Prophylactic Cr...
Brain X-ray
18 Years - M.D. Anderson Cancer Center
PCI in Advanced Triple Negative Breast Cancer Patients Who Response to 1st Line ChemotherapyNCT02448576
Breast Cancer
Brain Metastasi...
prophylactic cr...
18 Years - 65 YearsSun Yat-sen University
PCI for Patients With ES-SCLC After RCT:a Prospective Randomized StudyNCT04535739
Small-cell Lung...
prophylactic cr...
18 Years - 65 YearsChineseAMS
Neoadjuvant Therapy Combined With Radical Surgery for the Treatment of Small Cell Lung Cancer (SCLC) in II and IIIA StageNCT03523234
Small-cell Lung...
neoadjuvant che...
radical surgery...
prophylactic cr...
Chemotherapy
18 Years - Shanghai Pulmonary Hospital, Shanghai, China
Prophylactic Cranial Irradiation (PCI) vs Observation in Stage III NSCLCNCT01282437
Non Small Cell ...
Radical Treatme...
Stage III Non-S...
Prophylactic Cr...
18 Years - Maastricht Radiation Oncology
Hippocampal Prophylactic Cranial Irradiation for Small Cell Lung CancerNCT01797159
Small-cell Lung...
SCLC
Small Cell Lung...
Hippocampal-spa...
18 Years - 100 YearsSidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Temozolomide as Maintenance Therapy Following Induction Chemotherapy in Extensive Stage Small Cell Lung CancerNCT02772107
Extensive-stage...
Temozolomide
first-line chem...
Prophylactic cr...
thoracic radiot...
18 Years - 75 YearsChinese PLA General Hospital
Radiation Therapy in Treating Patients With Extensive Stage Small Cell Lung CancerNCT01055197
Lung Cancer
Prophylactic Cr...
Radiation Thera...
18 Years - Radiation Therapy Oncology Group
Prophylactic Cranial Irradiation in Patients With Lung Adenocarcinoma With High Risk of Brain MetastasisNCT01603849
Lung Cancer
Prophylactic Cr...
18 Years - 60 YearsInstituto Nacional de Cancerologia de Mexico
Hippocampus Avoidance PCI vs PCINCT01780675
Small Cell Lung...
Lung Cancer
Radiation Proph...
Radiation Hippo...
18 Years - The Netherlands Cancer Institute
Prophylactic Cranial Irradiation in Patients With HER-2-Positive Metastatic Breast CancerNCT00916877
Breast Cancer
Prophylactic Cr...
18 Years - AHS Cancer Control Alberta
Combined Modality Treatment for Resectable Non-Small Cell Superior Sulcus TumorsNCT00984997
Lung Cancer
Surgery
Chest Irradiati...
Cisplatin
Etoposide
Prophylactic Cr...
18 Years - 70 YearsM.D. Anderson Cancer Center
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