Spots Global Cancer Trial Database for chemotherapeutic agent toxicity
Every month we try and update this database with for chemotherapeutic agent toxicity cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.
The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
| Study title | NCT ID | Conditions | Interventions | Eligibility | Organization | Link |
|---|---|---|---|---|---|---|
| Changes in Semen or Sperm Caused by Temozolomide in Patients With Newly Diagnosed, Progressive, or Recurrent Primary Malignant Brain Tumors | NCT00499798 | Brain and Centr... Chemotherapeuti... Infertility | 18 Years - 60 Years | Wake Forest University Health Sciences | ||
| Nicotine Patches in Reducing Hand-Foot Syndrome in Patients Who Are Receiving Capecitabine For Metastatic Breast Cancer | NCT00751101 | Breast Cancer Chemotherapeuti... Palmar-plantar ... | Nicotine patch | 18 Years - 75 Years | University of California, San Francisco | |
| Diminish Chemotherapy Related Side Effects Through Patient Education | NCT04694794 | Chemotherapeuti... Chemotherapeuti... Chemotherapy Ef... | Educational Bro... | 18 Years - | Milton S. Hershey Medical Center | |
| L-Carnitine L-Tartrate in Preventing Peripheral Neuropathy Caused By Chemotherapy in Women With Metastatic Breast Cancer | NCT00754767 | Breast Cancer Chemotherapeuti... Neurotoxicity | L-carnitine L-t... placebo | 18 Years - 120 Years | HealthPartners Institute | |
| Investigating Paclitaxel Toxicity in Breast Cancer: The Roles of Physical Activity and Body Composition. | NCT06387901 | Breast Cancer Paclitaxel Adve... Chemotherapeuti... Chemotherapeuti... Body Weight Physical Inacti... | Paclitaxel Chem... | 18 Years - | Universitair Ziekenhuis Brussel | |
| Calcium Gluconate and Magnesium Sulfate in Preventing Neurotoxicity in Patients With Colon Cancer or Rectal Cancer Receiving Oxaliplatin-Based Combination Chemotherapy | NCT01099449 | Chemotherapeuti... Colorectal Canc... Neuropathy Neurotoxicity | calcium glucona... magnesium sulfa... placebo oxaliplatin | 18 Years - | Alliance for Clinical Trials in Oncology | |
| Cryotherapy in Preventing Peripheral Neuropathy and Nail Toxicity in Patients With Breast Cancer Who Are Receiving Paclitaxel | NCT01243541 | Chemotherapeuti... Pain Peripheral Neur... Recurrent Breas... Stage IA Breast... Stage IB Breast... Stage II Breast... Stage IIIA Brea... Stage IIIB Brea... Stage IIIC Brea... Stage IV Breast... Therapy-related... | cryotherapy questionnaire a... quality-of-life... management of t... assessment of t... | 18 Years - | Northwestern University | |
| Aerobic Exercise in Patients Receiving Chemotherapy for Cancer | NCT00728429 | Cardiac Toxicit... Chemotherapeuti... Unspecified Adu... | exercise interv... | 18 Years - 80 Years | Wake Forest University Health Sciences | |
| Methotrexate, Glucarpidase, and Leucovorin in Treating Patients With Newly Diagnosed Primary Central Nervous System Lymphoma | NCT00727831 | Chemotherapeuti... Lymphoma Mucositis Neurotoxicity | glucarpidase leucovorin calc... methotrexate laboratory biom... quality-of-life... radiation thera... | 18 Years - | University College, London | |
| Aerobic Exercise in Patients Receiving Chemotherapy for Cancer | NCT00728429 | Cardiac Toxicit... Chemotherapeuti... Unspecified Adu... | exercise interv... | 18 Years - 80 Years | Wake Forest University Health Sciences | |
| Sublingual Anvirzel in Advance Non-Small Cell Lung Cancer (NSCLC) | NCT01562301 | Chemotherapeuti... Lung Cancer | Carboplatin Docetaxel Anvirzel Questionnaires | 18 Years - | M.D. Anderson Cancer Center | |
| Investigating Paclitaxel Toxicity in Breast Cancer: The Roles of Physical Activity and Body Composition. | NCT06387901 | Breast Cancer Paclitaxel Adve... Chemotherapeuti... Chemotherapeuti... Body Weight Physical Inacti... | Paclitaxel Chem... | 18 Years - | Universitair Ziekenhuis Brussel | |
| Chemotherapy With or Without Dalteparin in Treating Patients With Metastatic Pancreatic Cancer | NCT00662688 | Chemotherapeuti... Pancreatic Canc... Thromboembolism | daltéparine Chemotherapy at... | 18 Years - 80 Years | GERCOR - Multidisciplinary Oncology Cooperative Group | |
| Investigating Paclitaxel Toxicity in Breast Cancer: The Roles of Physical Activity and Body Composition. | NCT06387901 | Breast Cancer Paclitaxel Adve... Chemotherapeuti... Chemotherapeuti... Body Weight Physical Inacti... | Paclitaxel Chem... | 18 Years - | Universitair Ziekenhuis Brussel | |
| Pyridoxine in Preventing Hand-Foot Syndrome Caused by Capecitabine in Patients With Cancer | NCT00486213 | Dermatologic Co... Palmar-plantar ... Unspecified Adu... | pyridoxine hydr... Placebo | 18 Years - | National Cancer Centre, Singapore | |
| Selenomethionine in Reducing Mucositis in Patients With Locally Advanced Head and Neck Cancer Who Are Receiving Cisplatin and Radiation Therapy | NCT01682031 | Chemotherapeuti... Mucositis Radiation Toxic... Stage III Squam... Stage III Squam... Stage III Squam... Stage III Squam... Stage III Squam... Stage III Squam... Stage IV Squamo... Stage IV Squamo... Stage IV Squamo... Stage IV Squamo... Stage IV Squamo... Stage IV Squamo... Xerostomia | selenomethionin... placebo cisplatin radiation thera... quality-of-life... | 18 Years - | Roswell Park Cancer Institute | |
| Using Whole-Person-Care Guide in Patients Receiving Care for Cancer or Complications From Cancer Treatment | NCT00608738 | Chemotherapeuti... Infection Malnutrition Musculoskeletal... Neutropenia Radiation Toxic... Thrombocytopeni... Unspecified Adu... | informational i... medical chart r... questionnaire a... assessment of t... management of t... | 21 Years - | Northwestern University | |
| Glutamine in Preventing Peripheral Neuropathy in Patients With Multiple Myeloma Receiving Bortezomib | NCT01783522 | Chemotherapeuti... Multiple Myelom... Peripheral Neur... | glutamine quality-of-life... placebo | 18 Years - | Case Comprehensive Cancer Center | |
| Electrical Stimulation Therapy Using the MC5-A Scrambler in Reducing Peripheral Neuropathy Caused by Chemotherapy | NCT00952848 | Chemotherapeuti... Neurotoxicity Pain Peripheral Neur... Unspecified Adu... | questionnaire a... Sensory Neuropa... Quality of Life... MC5-A Scrambler... | 18 Years - 120 Years | Virginia Commonwealth University | |
| Acute Pain Caused by Paclitaxel in Patients With Cancer | NCT00860041 | Chemotherapeuti... Neurotoxicity Pain Unspecified Adu... | pain questionna... | 18 Years - | Alliance for Clinical Trials in Oncology | |
| Glutathione in Preventing Peripheral Neuropathy Caused by Paclitaxel and Carboplatin in Patients With Ovarian Cancer, Fallopian Tube Cancer, and/or Primary Peritoneal Cancer | NCT02311907 | Chemotherapeuti... Neuropathy Neurotoxicity S... Pain Stage IIIA Fall... Stage IIIA Ovar... Stage IIIA Prim... Stage IIIB Fall... Stage IIIB Ovar... Stage IIIB Prim... Stage IIIC Fall... Stage IIIC Ovar... Stage IIIC Prim... Stage IV Fallop... Stage IV Ovaria... Stage IV Primar... | Carboplatin Glutathione Laboratory Biom... Paclitaxel Placebo Quality-of-Life... | 18 Years - | Alliance for Clinical Trials in Oncology | |
| Sublingual Anvirzel in Advance Non-Small Cell Lung Cancer (NSCLC) | NCT01562301 | Chemotherapeuti... Lung Cancer | Carboplatin Docetaxel Anvirzel Questionnaires | 18 Years - | M.D. Anderson Cancer Center | |
| Nicotine Patches in Reducing Hand-Foot Syndrome in Patients Who Are Receiving Capecitabine For Metastatic Breast Cancer | NCT00751101 | Breast Cancer Chemotherapeuti... Palmar-plantar ... | Nicotine patch | 18 Years - 75 Years | University of California, San Francisco | |
| L-Carnitine L-Tartrate in Preventing Peripheral Neuropathy Caused By Chemotherapy in Women With Metastatic Breast Cancer | NCT00754767 | Breast Cancer Chemotherapeuti... Neurotoxicity | L-carnitine L-t... placebo | 18 Years - 120 Years | HealthPartners Institute | |
| Mobile App for Symptoms Monitoring in Cancer Patients: a Pilot Study | NCT04572282 | Cancer Symptoms and Si... Quality of Life Chemotherapeuti... | Mentora app | 18 Years - | Associacao de Investigacao de Cuidados de Suporte em Oncologia | |
| Chemo/XRT +/- Amifostine to Assess Outcomes Related to Xerostomia, Mucositis, & Dysphagia | NCT00503776 | Dysphagia Head and Neck C... Mucositis Xerostomia | exercise interv... amifostine trih... therapeutic die... | 21 Years - | Vanderbilt-Ingram Cancer Center | |
| Glutamine in Preventing Peripheral Neuropathy in Patients With Multiple Myeloma Receiving Bortezomib | NCT01783522 | Chemotherapeuti... Multiple Myelom... Peripheral Neur... | glutamine quality-of-life... placebo | 18 Years - | Case Comprehensive Cancer Center | |
| Biomarkers in Predicting Neurotoxicity in Patients With Colorectal Cancer Receiving Oxaliplatin | NCT00884767 | Chemotherapeuti... Colorectal Canc... Neurotoxicity | FOLFOX regimen fluorouracil leucovorin calc... oxaliplatin gene expression... protein express... proteomic profi... laboratory biom... pharmacogenomic... | 18 Years - | National Cancer Institute (NCI) | |
| Cryotherapy in Preventing Peripheral Neuropathy and Nail Toxicity in Patients With Breast Cancer Who Are Receiving Paclitaxel | NCT01243541 | Chemotherapeuti... Pain Peripheral Neur... Recurrent Breas... Stage IA Breast... Stage IB Breast... Stage II Breast... Stage IIIA Brea... Stage IIIB Brea... Stage IIIC Brea... Stage IV Breast... Therapy-related... | cryotherapy questionnaire a... quality-of-life... management of t... assessment of t... | 18 Years - | Northwestern University | |
| S0715: Acetyl-L-Carnitine in Preventing Neuropathy in Women With Stage I, II, or IIIA Breast Cancer Undergoing Chemo | NCT00775645 | Breast Cancer Chemotherapeuti... Fatigue Neuropathy Neurotoxicity | acetyl-L-carnit... placebo | 18 Years - 120 Years | SWOG Cancer Research Network | |
| Cryotherapy vs. Cryocompression for Preventing Chemotherapy-induced-peripheral-neuropathy in Women Undergoing Chemotherapy | NCT04632797 | Chemotherapy-in... Chemotherapeuti... Chemotherapeuti... | Hilotherm Chemo... | 18 Years - 99 Years | Medical University Innsbruck | |
| Telemonitoring Platforms and Chemotherapy-Associated Toxicity | NCT06077123 | Cancer Chemotherapeuti... | Contigo Applica... | 18 Years - | Universidad Nacional Andres Bello | |
| Acute Pain Caused by Paclitaxel in Patients With Cancer | NCT00860041 | Chemotherapeuti... Neurotoxicity Pain Unspecified Adu... | pain questionna... | 18 Years - | Alliance for Clinical Trials in Oncology | |
| Randomized Amifostine For SCCHN | NCT00095927 | Chemotherapeuti... Head and Neck C... Mucositis Radiation Toxic... Xerostomia | Amifostine Carboplatin Paclitaxel radiation | 18 Years - | Dana-Farber Cancer Institute | |
| S0715: Acetyl-L-Carnitine in Preventing Neuropathy in Women With Stage I, II, or IIIA Breast Cancer Undergoing Chemo | NCT00775645 | Breast Cancer Chemotherapeuti... Fatigue Neuropathy Neurotoxicity | acetyl-L-carnit... placebo | 18 Years - 120 Years | SWOG Cancer Research Network | |
| Glutamine in Preventing Peripheral Neuropathy in Patients With Multiple Myeloma Receiving Bortezomib | NCT01783522 | Chemotherapeuti... Multiple Myelom... Peripheral Neur... | glutamine quality-of-life... placebo | 18 Years - | Case Comprehensive Cancer Center | |
| G-CSF in Preventing Neutropenia in Patients With Solid Tumors Who Are Receiving Chemotherapy | NCT00770172 | Chemotherapeuti... Neutropenia Unspecified Adu... | filgrastim | 18 Years - | National Cancer Institute (NCI) | |
| Biomarkers in Predicting Neurotoxicity in Patients With Colorectal Cancer Receiving Oxaliplatin | NCT00884767 | Chemotherapeuti... Colorectal Canc... Neurotoxicity | FOLFOX regimen fluorouracil leucovorin calc... oxaliplatin gene expression... protein express... proteomic profi... laboratory biom... pharmacogenomic... | 18 Years - | National Cancer Institute (NCI) | |
| Calcium Gluconate and Magnesium Sulfate in Preventing Neurotoxicity in Patients With Colon Cancer or Rectal Cancer Receiving Oxaliplatin-Based Combination Chemotherapy | NCT01099449 | Chemotherapeuti... Colorectal Canc... Neuropathy Neurotoxicity | calcium glucona... magnesium sulfa... placebo oxaliplatin | 18 Years - | Alliance for Clinical Trials in Oncology | |
| Diminish Chemotherapy Related Side Effects Through Patient Education | NCT04694794 | Chemotherapeuti... Chemotherapeuti... Chemotherapy Ef... | Educational Bro... | 18 Years - | Milton S. Hershey Medical Center | |
| Calcium Aluminosilicate Anti-Diarrheal in Treating and Preventing Diarrhea in Patients With Metastatic Colorectal Cancer Receiving Irinotecan | NCT00748215 | Chemotherapeuti... Colorectal Canc... Diarrhea | calcium alumino... placebo | 18 Years - | M.D. Anderson Cancer Center | |
| Nicotine Patches in Reducing Hand-Foot Syndrome in Patients Who Are Receiving Capecitabine For Metastatic Breast Cancer | NCT00751101 | Breast Cancer Chemotherapeuti... Palmar-plantar ... | Nicotine patch | 18 Years - 75 Years | University of California, San Francisco | |
| G-CSF in Preventing Neutropenia in Patients With Solid Tumors Who Are Receiving Chemotherapy | NCT00770172 | Chemotherapeuti... Neutropenia Unspecified Adu... | filgrastim | 18 Years - | National Cancer Institute (NCI) |
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