Spots Global Cancer Trial Database for natural history
Every month we try and update this database with for natural history cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.
The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
| Study title | NCT ID | Conditions | Interventions | Eligibility | Organization | Link |
|---|---|---|---|---|---|---|
| Hearing Loss and the Effects of Statin Drugs in People With Head and Neck Squamous Cell Carcinoma Treated With Cisplatin Chemoradiation | NCT03225157 | Head and Neck N... Hearing Disorde... Hyperlipidemia | 18 Years - | National Institutes of Health Clinical Center (CC) | ||
| Clinical, Genetic, Behavioral, Laboratory and Epidemiologic Characterization of Individuals and Families at High Risk of Breast/Ovarian Cancer | NCT00040222 | Familial Ovaria... Familial Breast... BRCA1-associate... BRCA2-associate... | 18 Years - 100 Years | National Institutes of Health Clinical Center (CC) | ||
| Tissue Collection for Studies of Lymph Cancer | NCT01676805 | Hodgkin Disease Lymphoma, Non-H... Multiple Myelom... Lymphomatoid Gr... Leukemia-Lympho... | 18 Years - | National Institutes of Health Clinical Center (CC) | ||
| Clinical and Genetic Studies in Familial Non-medullary Thyroid Cancer | NCT01109420 | Non-Medullary T... | 7 Years - 90 Years | National Institutes of Health Clinical Center (CC) | ||
| Tumor Related Epilepsy | NCT02639325 | Epilepsy Cancer Brain Neoplasm | 8 Years - 99 Years | National Institutes of Health Clinical Center (CC) | ||
| Biospecimen Procurement for Head and Neck Disorders | NCT03429036 | Hearing Disorde... Oral Mucosal Di... Pharyngeal Neop... Head and Neck N... Laryngeal Disea... | 3 Years - 120 Years | National Institutes of Health Clinical Center (CC) | ||
| Collection of Blood, Bone Marrow, Skin, Saliva, and Stool Samples From Healthy Volunteers Used for Comparative Analysis of Myeloid Malignancies | NCT05588154 | Myelodysplastic... | 18 Years - | National Institutes of Health Clinical Center (CC) | ||
| High-Risk Breast Duct Epithelium | NCT00028340 | Breast Cancer | 18 Years - 74 Years | National Institutes of Health Clinical Center (CC) | ||
| Natural History of Familial Carcinoid Tumor | NCT00646022 | Carcinoid | [18F]-DOPA | 18 Years - | National Institutes of Health Clinical Center (CC) | |
| M7824 Related Adverse Effects in Adults With Cancer | NCT04267861 | Neoplasms Skin Neoplasms | 18 Years - | National Institutes of Health Clinical Center (CC) | ||
| Retrospective Analysis of a Drug-Metabolizing Genotype in Cancer Patients and Correlation With Pharmacokinetic and Pharmacodynamics Data | NCT00341939 | Prostate Cancer Breast Cancer Cutaneous T-Cel... Lung Cancer Melanoma | 18 Years - | National Institutes of Health Clinical Center (CC) | ||
| Cancer in Inherited Bone Marrow Failure Syndromes | NCT00027274 | Diamond Blackfa... Dyskeratosis Co... Fanconi Anemia Shwachman Diamo... Inherited Bone ... | - | National Institutes of Health Clinical Center (CC) | ||
| CAR-Multicenter Analysis (CAR-MA): Retrospective Study to Characterize CAR T-cell Outcomes and Related Toxicities in Children and Young Adults With B-ALL | NCT05440409 | Leukemia, Acute... Lymphoblastic L... | 3 Years - 25 Years | National Institutes of Health Clinical Center (CC) | ||
| Obtaining Solid Tumor Tissue From People Having Biopsy or Surgery for Certain Types of Cancer | NCT01915225 | Colorectal Neop... Gastric Neoplas... Cholangiocarcin... Bile Duct Cance... Pancreas Cancer | 2 Years - | National Institutes of Health Clinical Center (CC) | ||
| A Prospective Study of Diet and Cancer in Members of the American Association of Retired Persons | NCT00340015 | Death Cancer | 50 Years - 71 Years | National Institutes of Health Clinical Center (CC) | ||
| Precision-Based Genomics in Prostate Cancer | NCT04706663 | Prostate Cancer | 18 Years - | National Institutes of Health Clinical Center (CC) | ||
| Natural History, Epidemiology and Pathogenesis of Severe HPV-Related Diseases (Neptune) | NCT05026138 | Human Papilloma... | 3 Years - | National Institutes of Health Clinical Center (CC) | ||
| Biology Studies of Hematologic Cancers | NCT00923442 | Acute Lymphobla... Myelodysplastic... Non-Hodgkins Ly... Acute Myelogeno... Hodgkins Lympho... | 1 Year - 75 Years | National Institutes of Health Clinical Center (CC) | ||
| Follow-Up Study of Subjects Previously Enrolled in Poxviral Vector Gene Transfer Studies | NCT00451022 | Prostate Cancer Liver Cancer Breast Cancer Colon Cancer Lung Cancer | 18 Years - | National Institutes of Health Clinical Center (CC) | ||
| Harvesting Cells for Experimental Cancer Treatments | NCT00068003 | Melanoma Gastrointestina... Metastatic Canc... Breast Cancer Non-Small Cell ... | Anti-CD19 CAR P... | 18 Years - | National Institutes of Health Clinical Center (CC) | |
| Children and Adults With Chordoma | NCT03910465 | Chordoma | 2 Years - | National Institutes of Health Clinical Center (CC) | ||
| Hereditary Leiomyomatosis Renal Cell Cancer - Study of the Genetic Cause and the Predisposition to Renal Cancer | NCT00050752 | Renal Tumor His... Cutaneous Leiom... Kidney Cancer | 2 Years - | National Institutes of Health Clinical Center (CC) | ||
| Rare CNS Tumors Outcomes &Risk | NCT03251989 | High Grade Meni... Ependymoma Medulloblastoma PNET Primary CNS Sar... | 18 Years - | National Institutes of Health Clinical Center (CC) | ||
| Men at High Genetic Risk for Prostate Cancer | NCT03805919 | Prostatic Neopl... | 30 Years - 75 Years | National Institutes of Health Clinical Center (CC) | ||
| Study of Proteus Syndrome and Related Congenital Disorders | NCT00001403 | Proteus Syndrom... PIK3CA Related ... | 1 Month - 99 Years | National Institutes of Health Clinical Center (CC) | ||
| Natural History Study of Patients With Neurofibromatosis Type I | NCT00924196 | Neurofibromatos... Malignant Perip... Plexiform Neuro... Optic Glioma Neurofibroma | 4 Weeks - | National Institutes of Health Clinical Center (CC) | ||
| Collection of Tissue Specimens From Patients With Solid Tumors or Blood Disorders and Their HLA-Compatible Family Members | NCT00071045 | Neoplasms Hematologic Neo... Healthy Volunte... | 2 Years - 100 Years | National Institutes of Health Clinical Center (CC) | ||
| Tissue Procurement and Natural History Study of Patients With Malignant Mesothelioma | NCT01950572 | Mesothelioma Thymoma Pancreatic Neop... Biliary Tract N... Stomach Neoplas... | 2 Years - | National Institutes of Health Clinical Center (CC) | ||
| Clinical, Laboratory and Epidemiologic Characterization of Individuals and Families at High Risk of Hematologic Cancer | NCT00039676 | Waldenstrom Mac... Chronic Lymphoc... Hodgkin Disease NonHodgkin Lymp... Mixed Lymphopro... | 11 Months - | National Institutes of Health Clinical Center (CC) | ||
| Examination of Clinical and Laboratory Abnormalities in Patients With Defective DNA Repair: Xeroderma Pigmentosum, Cockayne Syndrome, or Trichothiodystrophy | NCT00001813 | Cockayne Syndro... Skin Neoplasms Xeroderma Pigme... Trichothiodystr... Genodermatosis | 6 Weeks - | National Institutes of Health Clinical Center (CC) | ||
| Study of Skin Tumors in Tuberous Sclerosis | NCT00001975 | Tuberous Sclero... | 18 Years - 90 Years | National Institutes of Health Clinical Center (CC) | ||
| Data Collection Study of Pediatric and Adolescent Gynecology Conditions | NCT04717349 | Disorders of Se... Pediatric and A... Reproductive En... Structural Gyne... | - | National Institutes of Health Clinical Center (CC) | ||
| Natural History of and Specimen Banking for People With Tumors of the Central Nervous System | NCT02851706 | Brain Cancer Brain Tumor Spine Cancer Spine Tumor Neoplasm | No Treatment | 18 Years - | National Institutes of Health Clinical Center (CC) | |
| Tissue Procurement and Natural History Study of Patients With Malignant Mesothelioma | NCT01950572 | Mesothelioma Thymoma Pancreatic Neop... Biliary Tract N... Stomach Neoplas... | 2 Years - | National Institutes of Health Clinical Center (CC) | ||
| Tissue Acquisition and Genomics Analysis of Breast Cancer and Other Gynecologic Malignancies | NCT03762733 | Breast Cancer Ovarian Cancer Uterine Cancer | 18 Years - | National Institutes of Health Clinical Center (CC) | ||
| Natural History Study of Children and Adults With Neuroendocrine Neoplasms (NEN)s | NCT04488263 | Neuroendocrine ... Carcinoma, Neur... | 3 Years - | National Institutes of Health Clinical Center (CC) | ||
| Clinical, Laboratory, and Epidemiologic Characterization of Individuals and Families at High Risk of Melanoma | NCT00040352 | Melanoma Dysplastic Nevu... | 4 Weeks - | National Institutes of Health Clinical Center (CC) | ||
| Precision-Based Genomics in Prostate Cancer | NCT04706663 | Prostate Cancer | 18 Years - | National Institutes of Health Clinical Center (CC) | ||
| Tissue Procurement and Natural History Study of Neuroendocrine Neoplasms (NENs) Including Adrenocortical Carcinoma (ACC) | NCT05237934 | Neuroendocrine ... Carcinoma, Neur... | 18 Years - | National Institutes of Health Clinical Center (CC) | ||
| Discovery of Sirolimus Sensitive Biomarkers in Blood | NCT03304678 | Lymphangioleiom... | Sirolimus 2mg | 18 Years - 90 Years | National Institutes of Health Clinical Center (CC) | |
| Genetic Clues to Chordoma Etiology: A Protocol to Identify Sporadic Chordoma Patients for Studies of Cancer-Susceptibility Genes | NCT01200680 | Genes Sporadic Chordo... | 6 Years - | National Institutes of Health Clinical Center (CC) | ||
| Biospecimen Procurement for Center for Immuno-Oncology Immunotherapy Protocols | NCT02682667 | Multiple Myelom... Lymphoma, Non-H... Leukemia-Lympho... Hodgkin Disease Non-Small Cell ... | 18 Years - 120 Years | National Institutes of Health Clinical Center (CC) | ||
| The Natural History of Solid Organ Cancer Stem Cells (SOCSC) | NCT00923052 | Hepatic Cancer Pancreatic Duct... Colorectal Canc... Breast Cancer Gastric Cancer | 16 Years - 100 Years | National Institutes of Health Clinical Center (CC) | ||
| Integrated Genomic Prostate Score With MRI Targeted Prostate Biopsies | NCT04541030 | Prostate Cancer | 18 Years - | National Institutes of Health Clinical Center (CC) | ||
| Assessment of Volumetric Growth Rates of Spinal Intradural Extramedullary Schwannoma | NCT01951365 | Schwannoma Neurinoma | 20 Years - | Seoul National University Hospital | ||
| Gene Therapy Follow-up Protocol for People Previously Enrolled in CAR-T Cell Studies | NCT02473757 | Lyphoma, B-Cell Leukemia, B-cel... Multiple Myelom... Hematologic Mal... | 18 Years - | National Institutes of Health Clinical Center (CC) | ||
| Nutrition Intervention Trials in Linxian Follow-up Study | NCT00342654 | Esophageal Canc... Gastric Cancer | 18 Years - 100 Years | National Institutes of Health Clinical Center (CC) | ||
| Comprehensive Omics Analysis of Pediatric Solid Tumors and Establishment of a Repository for Related Biological Studies | NCT01109394 | Sarcoma Endocrine Tumor... Neuroblastoma Retinoblastoma Renal Cancer | 4 Weeks - | National Institutes of Health Clinical Center (CC) | ||
| Incidence of Malignant Peripheral Nerve Sheath Tumor (MPNST) Development in Participants With Neurofibromatosis Type 1 (NF1) Receiving and Not Receiving Medical Therapies Directed at Plexiform Neurofibromas (PN) | NCT04774289 | Neurofibromatos... Peripheral Nerv... | 1 Month - | National Institutes of Health Clinical Center (CC) | ||
| Data Collection, Clinical Care and Interventions in CCR, NCI | NCT00923065 | Neoplasms Cancer | 4 Weeks - 120 Years | National Institutes of Health Clinical Center (CC) | ||
| Where Culture Meets Genetics: Exploring Latinas Causal Attributions of Breast and Colon Cancer and Models of Disease Inheritance | NCT02767986 | Colon Cancer Breast Cancer | 18 Years - 75 Years | National Institutes of Health Clinical Center (CC) | ||
| Characterizing Fatigue Experienced by Cancer Patients Receiving Primary Treatment and Cancer Survivors | NCT01231932 | Cancer Fatigue Prostate Cancer Breast Cancer Cancer Survivor | 18 Years - 120 Years | National Institutes of Health Clinical Center (CC) | ||
| A Natural History Study of Children and Adults With Olfactory Neuroblastoma | NCT04755205 | Olfactory Neuro... Esthesioneurobl... | 3 Years - 120 Years | National Institutes of Health Clinical Center (CC) | ||
| Assessing Sleep and Circadian Rhythms in Primary Brain Tumors Patients | NCT04669574 | Sleep Circadian... Chronodisruptio... | 18 Years - 99 Years | National Institutes of Health Clinical Center (CC) | ||
| Blood Collection From People With Ovarian Cancer | NCT02063464 | Ovarian Cancer Cancer of the O... Ovarian Neoplas... | 18 Years - | National Institutes of Health Clinical Center (CC) | ||
| Acquisition of Blood and Tumor Tissue Samples From Patients With Gastrointestinal Cancer | NCT01313442 | Non-GI Cancers Cancer of Gastr... Gastrointestina... | 18 Years - | National Institutes of Health Clinical Center (CC) | ||
| Clinical and Laboratory Analysis of Familial Cancer | NCT02565004 | Cancer | 10 Years - | National Institutes of Health Clinical Center (CC) | ||
| Imaging Studies to Check the Local Response of Prostate Cancer to Radiation Therapy | NCT01834001 | Prostatic Neopl... Prostate Cancer | 18 Years - | National Institutes of Health Clinical Center (CC) | ||
| Data Collection of Standard Care and Evaluation of NHLBI Patients and Donors | NCT04450927 | Wide Spectrum o... Hematologic Dis... | 2 Years - 120 Years | National Institutes of Health Clinical Center (CC) | ||
| Genetic Analysis of Birt Hogg-Dube Syndrome and Characterization of Predisposition to Kidney Cancer | NCT00033137 | Kidney Neoplasm... Kidney Cancer Pneumothorax FLCN Protein, H... | 2 Years - | National Institutes of Health Clinical Center (CC) | ||
| Incidence of Malignant Peripheral Nerve Sheath Tumor (MPNST) Development in Participants With Neurofibromatosis Type 1 (NF1) Receiving and Not Receiving Medical Therapies Directed at Plexiform Neurofibromas (PN) | NCT04774289 | Neurofibromatos... Peripheral Nerv... | 1 Month - | National Institutes of Health Clinical Center (CC) | ||
| Natural History Study of Patients With Neurofibromatosis Type I | NCT00924196 | Neurofibromatos... Malignant Perip... Plexiform Neuro... Optic Glioma Neurofibroma | 4 Weeks - | National Institutes of Health Clinical Center (CC) | ||
| Evaluation of Women With Endocrine and Reproductive-Related Conditions | NCT00001850 | Endocrine Disea... Infertility Leiomyoma Endometriosis Fibroids | 1 Year - 85 Years | National Institutes of Health Clinical Center (CC) | ||
| Agriculture Health Study | NCT00352924 | Prostate Cancer Pesticide Expos... Lymphoma Multiple Myelom... | 18 Years - | National Institutes of Health Clinical Center (CC) | ||
| Collecting Solid Tumor Tissue to Identify New Treatments | NCT01658917 | Gastrointestina... Liver Cancer Pancreatic Canc... Melanoma | 18 Years - | National Institutes of Health Clinical Center (CC) | ||
| Molecular-Genetic Correlates of Fatigue in Cancer Patients Receiving Localized External Beam Radiation Therapy | NCT00852111 | Cancer Fatigue | 18 Years - | National Institutes of Health Clinical Center (CC) | ||
| Evaluation of Late Effects and Natural History of Disease in Patients Treated With Radiotherapy | NCT00026650 | Cancer | 18 Years - | National Institutes of Health Clinical Center (CC) | ||
| Clonal Evolution in Follicular Lymphoma | NCT03190928 | Follicular Lymp... | 18 Years - | National Institutes of Health Clinical Center (CC) | ||
| Tumor Related Epilepsy | NCT02639325 | Epilepsy Cancer Brain Neoplasm | 8 Years - 99 Years | National Institutes of Health Clinical Center (CC) | ||
| Hearing Loss and the Effects of Statin Drugs in People With Head and Neck Squamous Cell Carcinoma Treated With Cisplatin Chemoradiation | NCT03225157 | Head and Neck N... Hearing Disorde... Hyperlipidemia | 18 Years - | National Institutes of Health Clinical Center (CC) | ||
| A Nested Case-Control Study of Lung Cancer and Diesel Exhaust Among Non-Metal Miners | NCT00342264 | Lung Cancer | 18 Years - | National Institutes of Health Clinical Center (CC) | ||
| Coordinating Center: Natural History of Barrett's Esophagus Using Tethered Capsule Endomicroscopy | NCT03459339 | Barrett Esophag... | Tethered Capsul... | 18 Years - | Massachusetts General Hospital | |
| Harvesting Cells for Experimental Cancer Treatments | NCT00068003 | Melanoma Gastrointestina... Metastatic Canc... Breast Cancer Non-Small Cell ... | Anti-CD19 CAR P... | 18 Years - | National Institutes of Health Clinical Center (CC) | |
| Study of Mast Cell Precursors | NCT00001756 | Mastocytosis Healthy Volunte... | 18 Years - 70 Years | National Institutes of Health Clinical Center (CC) | ||
| Follow-up Protocol for Patients With Cancer/AIDS/Skin Disease | NCT00001503 | Melanoma Ovarian Cancer Prostate Cancer Breast Cancer Lymphoma | 1 Month - | National Institutes of Health Clinical Center (CC) | ||
| Study of the Disease Process of Lymphangioleiomyomatosis | NCT00001465 | Lung Disease Pneumothorax Tuberous Sclero... Lymphangioleiom... | Toshibia Aquili... | 16 Years - 100 Years | National Institutes of Health Clinical Center (CC) | |
| Natural History Study of Patients With Neurofibromatosis Type 2 | NCT00598351 | Neurofibromatos... | 8 Years - 75 Years | National Institutes of Health Clinical Center (CC) | ||
| M7824 Related Adverse Effects in Adults With Cancer | NCT04267861 | Neoplasms Skin Neoplasms | 18 Years - | National Institutes of Health Clinical Center (CC) | ||
| A Natural History Study of Bone and Mineral Disorders | NCT00024804 | Tumor Induced O... Osteomalacia Familial Tumora... | 1 Day - | National Institutes of Health Clinical Center (CC) | ||
| Retinoblastoma Biomarker Study | NCT00342797 | Retinoblastoma Melanoma Sarcoma | 7 Years - | National Institutes of Health Clinical Center (CC) |
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