Spots Global Cancer Trial Database for ngs
Every month we try and update this database with for ngs cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.
The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
| Study title | NCT ID | Conditions | Interventions | Eligibility | Organization | Link |
|---|---|---|---|---|---|---|
| A Prospective Study Utilizing Circulating Cell Free DNA (cfDNA) Use in the Detection of RAS Mutations in Patients With Advanced Colorectal Cancer. | NCT04775862 | Colon Cancer | investigator ch... | 18 Years - | National Guard Health Affairs | |
| Ambispective Cohort Study of Precision Medicine for Primary Hepatobiliary Cancer Based on Next-generation Sequencing | NCT05520788 | Hepatocellular ... Biliary Tract C... | precise medicin... | 18 Years - | Tongji Hospital | |
| Next-generation Sequencing in Gastrointestinal Cancer | NCT03476057 | Gastrointestina... | Device： NGS seq... | - | Fujian Cancer Hospital | |
| Precision Diagnosis Directing HDACi Chidamide Target Therapy for Adult T-LBL/ALL | NCT03564704 | Leukemia Leukemia, Acute Adult Lymphobla... Leukemia, Lymph... Leukemia, T Cel... Adult Acute Lym... Lymphoblastic L... Lymphoblastic L... | Dexamethasone vincristine Cyclophosphamid... Idarubicin Pegaspargase Adriamycin Methotrexate 6-mercaptopurin... Etoposide Cytarabine Bone marrow asp... Intrathecal inj... Radiation thera... NGS allogeneic hema... Flow-MRD FISH Flow immunophen... Karyotyping Chidamide PET-CT scan | 14 Years - 55 Years | Nanfang Hospital, Southern Medical University | |
| Precise Treatment in Hepatobiliary Cancers (PTHBC) | NCT02715089 | Liver Neoplasms Biliary Tract N... Hepatobiliary N... | Precise treatme... | 18 Years - 65 Years | Peking Union Medical College Hospital | |
| A Biomarker-driven, Open Label, Single Arm, Multicentre Phase II Study of Abemaciclib in Patients With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma Who Failed to Platinum-based Therapy | NCT03356587 | HNSCC Head and Neck N... | Abemaciclib | 20 Years - | Seoul National University Hospital | |
| Precision Diagnosis for Intraoperative Frozen Section of Early Stage Lung Cancer | NCT02941003 | Lung Cancer | microscope immunostaining NGS | 40 Years - 70 Years | Shanghai Chest Hospital | |
| Uniportal Tubeless VATS for the Evaluation of Biopsy for Second-generation Sequencing in Patients With Advanced NSCLC | NCT04950907 | NSCLC Biopsy Techniqu... VATS CT Guided Punct... NGS | vats CT-guided fine ... | 18 Years - 75 Years | The First Affiliated Hospital of Guangzhou Medical University | |
| Cancer Panel From Blood of Lung Cancer Patients | NCT03235765 | Non Small Cell ... Non Small Cell ... | MACROGEN Pan Ca... | 20 Years - | Seoul National University Hospital | |
| NSCLC Heterogeneity in Early Stage Patients and Prediction of Relapse Using a Personalized "Liquid Biopsy" | NCT03771404 | Non Small Cell ... | blood sampling | 18 Years - | Hellenic Oncology Research Group | |
| The PLATON Network | NCT05489250 | Hepatocellular ... Cholangiocarcin... Gallbladder Can... Pancreatic Canc... Oesophageal Can... Stomach Cancer | 18 Years - | Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest | ||
| A Biomarker-driven, Open Label, Single Arm, Multicentre Phase II Study of Abemaciclib in Patients With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma Who Failed to Platinum-based Therapy | NCT03356587 | HNSCC Head and Neck N... | Abemaciclib | 20 Years - | Seoul National University Hospital | |
| Biomolecular Analysis for Predicting Response to Regorafenib | NCT05759195 | Glioblastoma Glioblastoma, I... | Biomolecular tu... | 18 Years - | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | |
| Development of Diagnostics and Treatment of Urological Cancers | NCT02994758 | Prostate Carcin... Kidney Cancer Urothelial Carc... Testicular Canc... Penile Cancer | Personalised tr... | 18 Years - | Helsinki University Central Hospital | |
| KEAPSAKE: A Study of Telaglenastat (CB-839) With Standard-of-Care Chemoimmunotherapy in 1L KEAP1/NRF2-Mutated, Nonsquamous NSCLC | NCT04265534 | Non-Small Cell ... Non-squamous No... Non-Squamous No... KEAP1 Gene Muta... NRF2 Gene Mutat... NFE2L2 Gene Mut... | Telaglenastat Carboplatin Che... Pemetrexed Chem... Pembrolizumab I... Placebo Folic acid 400 ... Vitamin B12 100... Dexamethasone 4... | 18 Years - | Calithera Biosciences, Inc | |
| Next Generation Sequencing（NGS）Monitors Minimal Residual Disease（MRD）in Allo-PBSCT Patients | NCT04126967 | NGS Monitor MRD | NGS patients | 18 Years - 70 Years | Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine | |
| NSCLC Heterogeneity in Early Stage Patients and Prediction of Relapse Using a Personalized "Liquid Biopsy" | NCT03771404 | Non Small Cell ... | blood sampling | 18 Years - | Hellenic Oncology Research Group | |
| LIQUIK: LIQUId Biopsy for Detection of Actionable Genomic BiomarKers in Patients With Advanced Non-small Cell Lung Cancer (NSCLC) | NCT04703153 | Non Small Cell ... | 21 Years - | Lucence Health Inc. | ||
| Prospective Evaluation of Diagnosis and Treatment of Patients With Autoimmune Cytopenias Including Autoimmune Hemolytic Anemia, Immune Thrombocytopenia, and Chronic Idiopathic/Autoimmune Neutropenia | NCT05931718 | Autoimmune Hemo... Immune Thromboc... Chronic Idiopat... Autoimmune Neut... Myelodysplastic... Cold Agglutinin... | cytokine essays NGS Fecal microbiom... Erythropoietin Luspatercept Thrombopoietin ... G-CSF | 18 Years - | Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico | |
| The Role of Gut Microbiome and Chronic Inflammation in Young-onset Colorectal Cancer | NCT04011969 | Colorectal Canc... | Score assessmen... Blood sampling Fecal sampling | 35 Years - | Fakultas Kedokteran Universitas Indonesia | |
| A Longitudinal Multi-Omic Biomarker Profiling Study of Patients With Head & Neck Squamous Cell Carcinoma (HNSCC) | NCT06163534 | Head and Neck S... | 18 Years - | Tempus AI | ||
| NGS and TME for Evidence-based Treatment of Pancreatic Cancer | NCT02767700 | Pancreatic Duct... | NGS | 18 Years - 75 Years | Karolinska University Hospital | |
| Prospective Evaluation of Diagnosis and Treatment of Patients With Autoimmune Cytopenias Including Autoimmune Hemolytic Anemia, Immune Thrombocytopenia, and Chronic Idiopathic/Autoimmune Neutropenia | NCT05931718 | Autoimmune Hemo... Immune Thromboc... Chronic Idiopat... Autoimmune Neut... Myelodysplastic... Cold Agglutinin... | cytokine essays NGS Fecal microbiom... Erythropoietin Luspatercept Thrombopoietin ... G-CSF | 18 Years - | Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico | |
| NSCLC Heterogeneity in Early Stage Patients and Prediction of Relapse Using a Personalized "Liquid Biopsy" | NCT03771404 | Non Small Cell ... | blood sampling | 18 Years - | Hellenic Oncology Research Group | |
| Precision Diagnosis Directing HDACi Chidamide Target Therapy for Adult ETP-ALL | NCT03553238 | Leukemia, Acute Leukemia, T Cel... Leukemia, Lymph... | Chidamide Dexamethasone vincristine Cyclophosphamid... Idarubicin Pegaspargase Adriamycin Methotrexate 6-Mercaptopurin... Etoposide Cytarabine Bone marrow asp... Intrathecal inj... Radiation thera... NGS allogeneic hema... Flow-MRD FISH Flow immunophen... Karyotyping | 14 Years - 55 Years | Nanfang Hospital, Southern Medical University | |
| The PLATON Network | NCT05489250 | Hepatocellular ... Cholangiocarcin... Gallbladder Can... Pancreatic Canc... Oesophageal Can... Stomach Cancer | 18 Years - | Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest | ||
| Precision Diagnosis Directing HDACi Chidamide Target Therapy for Adult ETP-ALL | NCT03553238 | Leukemia, Acute Leukemia, T Cel... Leukemia, Lymph... | Chidamide Dexamethasone vincristine Cyclophosphamid... Idarubicin Pegaspargase Adriamycin Methotrexate 6-Mercaptopurin... Etoposide Cytarabine Bone marrow asp... Intrathecal inj... Radiation thera... NGS allogeneic hema... Flow-MRD FISH Flow immunophen... Karyotyping | 14 Years - 55 Years | Nanfang Hospital, Southern Medical University | |
| Precise Treatment in Hepatobiliary Cancers (PTHBC) | NCT02715089 | Liver Neoplasms Biliary Tract N... Hepatobiliary N... | Precise treatme... | 18 Years - 65 Years | Peking Union Medical College Hospital | |
| Next-generation Sequencing in Gastrointestinal Cancer | NCT03476057 | Gastrointestina... | Device： NGS seq... | - | Fujian Cancer Hospital | |
| KEAPSAKE: A Study of Telaglenastat (CB-839) With Standard-of-Care Chemoimmunotherapy in 1L KEAP1/NRF2-Mutated, Nonsquamous NSCLC | NCT04265534 | Non-Small Cell ... Non-squamous No... Non-Squamous No... KEAP1 Gene Muta... NRF2 Gene Mutat... NFE2L2 Gene Mut... | Telaglenastat Carboplatin Che... Pemetrexed Chem... Pembrolizumab I... Placebo Folic acid 400 ... Vitamin B12 100... Dexamethasone 4... | 18 Years - | Calithera Biosciences, Inc | |
| ctDNA for Early Detection of Recurrence in Melanoma | NCT06246227 | Melanoma | 18 Years - | Herlev and Gentofte Hospital | ||
| Identification of Molecular Biomarkers for Cancer Target Therapy Efficacy | NCT03724097 | Cancer | RNA sequencing Transcriptome a... target drug wit... target drug wit... non-target drug palliative care | 18 Years - 80 Years | OmicsWay Corp. | |
| NSCLC Heterogeneity in Early Stage Patients and Prediction of Relapse Using a Personalized "Liquid Biopsy" | NCT03771404 | Non Small Cell ... | blood sampling | 18 Years - | Hellenic Oncology Research Group | |
| Molecular Pathway Activation Markers Predicting Efficacy of Trastuzumab Therapy for HER2-positive Breast Cancer | NCT03521245 | HER2-positive B... | RNA sequencing Transcriptome a... Trastuzumab Chemotherapy | 18 Years - 80 Years | OmicsWay Corp. | |
| PRELUDE-1 (Prospective Evaluation of Radiotherapy-induced Biologic Effects in Colorectal Cancer Oligometastatic Patients With LUng-limited Disease: Evolution of Cancer Genetics and Regulatory Immune Cells) | NCT04854213 | Colorectal Canc... | Stereotactic Bo... | 18 Years - 80 Years | National Cancer Institute, Naples | |
| Evaluation of Efficacy and Toxicity of Nivolumab Monotherapy for Advanced Non-small Cell Lung Cancer After First-line Treatment Failure Based on Second-generation Sequencing and Liquid Chip Platform | NCT03692442 | Lung Cancer Non... | 18 Years - 65 Years | Guangzhou Institute of Respiratory Disease | ||
| A Study Evaluating the Safety and Efficacy of ENV-101 (Taladegib) in Patients With Advanced Solid Tumors Harboring PTCH1 Loss of Function Mutations | NCT05199584 | Solid Tumors Wi... | ENV-101 (talade... | 18 Years - | Endeavor Biomedicines, Inc. | |
| NGS Combined With RNAseq on Tumor Immune Escape in NSCLC | NCT03764917 | Non-small Cell ... | Time | 18 Years - 75 Years | Shanghai Pulmonary Hospital, Shanghai, China | |
| MyCustom:Prospective Master Protocol Trial on Precision Medicine Treatment for Refractory Solid Tumors | NCT06030869 | Refractory Soli... Next Generation... | 18 Years - | Tianjin Medical University Second Hospital | ||
| Tempus CRC Surveillance Study: A ctDNA Biomarker Profiling Study of Patients With CRC Using NGS Assays | NCT05234177 | Colorectal Canc... | Observation | 18 Years - | Tempus AI | |
| Tempus Sculptor Study: Small Cell Lung Cancer (SCLC) Observational Study | NCT05257551 | Small Cell Lung... | Observation | 18 Years - | Tempus AI | |
| Development of Diagnostics and Treatment of Urological Cancers | NCT02994758 | Prostate Carcin... Kidney Cancer Urothelial Carc... Testicular Canc... Penile Cancer | Personalised tr... | 18 Years - | Helsinki University Central Hospital | |
| Clinical Value of Next Generation Sequencing in Chinese Childhood Solid Tumors | NCT05076071 | Pediatric, Soli... | NGS | 0 Years - 18 Years | Sun Yat-sen University | |
| A Study of Sapanisertib in Relapsed/Refractory NFE2L2-Mutated and Wild-Type Squamous Non-Small Cell Lung Cancer | NCT05275673 | Non-Small Cell ... Squamous Non-sm... Squamous Non-Sm... NFE2L2 Gene Mut... | sapanisertib | 18 Years - | Calithera Biosciences, Inc | |
| Clinical Value of Next Generation Sequencing in Chinese Childhood Solid Tumors | NCT05076071 | Pediatric, Soli... | NGS | 0 Years - 18 Years | Sun Yat-sen University | |
| Biomolecular Analysis for Predicting Response to Regorafenib | NCT05759195 | Glioblastoma Glioblastoma, I... | Biomolecular tu... | 18 Years - | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | |
| The PLATON Network | NCT05489250 | Hepatocellular ... Cholangiocarcin... Gallbladder Can... Pancreatic Canc... Oesophageal Can... Stomach Cancer | 18 Years - | Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest |
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