Spots Global Cancer Trial Database for tumors metastatic to brain
Every month we try and update this database with for tumors metastatic to brain cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.
The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
| Study title | NCT ID | Conditions | Interventions | Eligibility | Organization | Link |
|---|---|---|---|---|---|---|
| Radiation Therapy Combined With Either Gefitinib or Temozolomide in Pats With NSCLC and Brain Metastases | NCT00238251 | Lung Cancer Metastatic Canc... | gefitinib temozolomide radiation thera... | 18 Years - | Swiss Group for Clinical Cancer Research | |
| Everolimus and Whole-Brain Radiation Therapy in Treating Patients With Brain Metastasis From Non-Small Cell Lung Cancer | NCT00892801 | Lung Cancer Metastatic Canc... | RAD001 whole-brain rad... | 18 Years - | Vanderbilt-Ingram Cancer Center | |
| Boron Neutron Capture Therapy in Treating Patients With Glioblastoma Multiforme or Melanoma Metastatic to the Brain | NCT00039572 | Brain and Centr... Melanoma (Skin) Metastatic Canc... | boronophenylala... | 18 Years - | National Cancer Institute (NCI) | |
| Combination Chemotherapy With or Without Peripheral Stem Cell Transplant in Treating Men With Previously Untreated Germ Cell Cancer | NCT00003941 | Mediastinal Can... Metastatic Canc... Testicular Germ... | bleomycin sulfa... filgrastim cisplatin etoposide ifosfamide bone marrow abl... peripheral bloo... | 16 Years - 50 Years | European Organisation for Research and Treatment of Cancer - EORTC | |
| Trastuzumab Plus R115777 in Treating Patients With Advanced or Metastatic Cancer | NCT00005842 | Cancer | trastuzumab tipifarnib | 18 Years - | National Cancer Institute (NCI) | |
| Temozolomide in Treating Patients With Primary Brain Tumors or Metastatic Brain Tumors | NCT00547131 | Brain and Centr... Metastatic Canc... | temozolomide laboratory biom... liquid chromato... mass spectromet... pharmacological... conventional su... stereotactic ra... | 18 Years - 120 Years | City of Hope Medical Center | |
| Radiation Therapy With or Without Radiosurgery in Treating Patients With Brain Metastases | NCT00002708 | Metastatic Canc... | surgical proced... radiation thera... stereotactic ra... | 18 Years - | Radiation Therapy Oncology Group | |
| Hypofractionated Image Guided Radiation Therapy in Treating Patients With Stage IV Breast Cancer | NCT01706432 | Central Nervous... Invasive Ductal... Invasive Ductal... Invasive Lobula... Invasive Lobula... Liver Metastase... Lobular Breast ... Lung Metastases Male Breast Can... Medullary Ducta... Mucinous Ductal... Papillary Ducta... Recurrent Breas... Stage IV Breast... Tubular Ductal ... Tumors Metastat... | hyperfractionat... laboratory biom... stereotactic ra... | 18 Years - | University of Chicago | |
| Stereotactic Radiosurgery in Treating Patients With Brain Metastases | NCT00811655 | Metastatic Canc... Unspecified Adu... | therapeutic con... stereotactic ra... | 18 Years - | Duke University | |
| CCI-779 in Treating Patients With Advanced Solid Tumors | NCT00003712 | Brain and Centr... Metastatic Canc... Unspecified Adu... | temsirolimus | 18 Years - | The University of Texas Health Science Center at San Antonio | |
| Photodynamic Therapy With Porfimer Sodium in Treating Patients With Refractory Brain Tumors | NCT00002647 | Brain and Centr... Metastatic Canc... | verteporfin conventional su... | 3 Years - 70 Years | National Cancer Institute (NCI) | |
| Phase 2 Etirinotecan Pegol in Refractory Brain Metastases & Advanced Lung Cancer / Metastatic Breast Cancer | NCT02312622 | Stage IV Non-sm... Recurrent Non-s... Extensive-stage... Recurrent Small... Tumors Metastat... Metastatic Brea... | Pegylated Irino... | 18 Years - | Stanford University | |
| Temozolomide and Vinorelbine in Treating Patients With Recurrent Brain Metastases | NCT00026494 | Metastatic Canc... | temozolomide vinorelbine tar... | 18 Years - | Memorial Sloan Kettering Cancer Center | |
| Phase 2 Etirinotecan Pegol in Refractory Brain Metastases & Advanced Lung Cancer / Metastatic Breast Cancer | NCT02312622 | Stage IV Non-sm... Recurrent Non-s... Extensive-stage... Recurrent Small... Tumors Metastat... Metastatic Brea... | Pegylated Irino... | 18 Years - | Stanford University | |
| Radiation Therapy With or Without Thalidomide in Treating Patients With Brain Metastases | NCT00033254 | Tumors Metastat... | radiation thera... thalidomide quality-of-life... | 18 Years - | National Cancer Institute (NCI) | |
| WBRT & Erlotinib in Advanced NSCLC and Brain Metastases | NCT00554775 | Lung Cancer Metastatic Canc... | erlotinib hydro... placebo | 18 Years - | University College, London | |
| Irinotecan and Temozolomide in Treating Patients With Breast Cancer Who Have Received Previous Treatment for Brain Metastases | NCT00617539 | Breast Cancer Metastatic Canc... | irinotecan hydr... temozolomide | 18 Years - 120 Years | University of California, San Francisco | |
| Radiolabeled Monoclonal Antibody Therapy in Treating Patients With Primary or Metastatic Brain Tumors | NCT00003461 | Brain and Centr... Metastatic Canc... Neuroblastoma | surgical proced... astatine At 211... | 18 Years - | Duke University | |
| Melphalan With BBBD in Treating Patients With Brain Malignancies | NCT00253721 | Brain and Centr... Lymphoma Metastatic Canc... | Melphalan | 18 Years - 120 Years | OHSU Knight Cancer Institute | |
| Study of Cerebrospinal Fluid Samples in Diagnosing Carcinomatous Meningitis in Patients With Cancer or Meningeal Syndrome | NCT00938756 | Brain and Centr... Breast Cancer Metastatic Canc... | diagnostic labo... immunoenzyme te... magnetic resona... | 18 Years - | National Cancer Institute (NCI) | |
| Radiation Therapy With or Without Thalidomide in Treating Patients With Brain Metastases | NCT00033254 | Tumors Metastat... | radiation thera... thalidomide quality-of-life... | 18 Years - | National Cancer Institute (NCI) | |
| Stereotactic Radiosurgery in Treating Patients With Brain Metastases | NCT00811655 | Metastatic Canc... Unspecified Adu... | therapeutic con... stereotactic ra... | 18 Years - | Duke University | |
| Bendamustine and Radiation Therapy in Treating Patients With Brain Metastases Caused by Solid Tumors | NCT00837928 | Metastatic Canc... Unspecified Adu... | bendamustine laboratory biom... Surgical Resect... Stereotactic bo... | 18 Years - | Ohio State University Comprehensive Cancer Center | |
| Bendamustine and Radiation Therapy in Treating Patients With Brain Metastases Caused by Solid Tumors | NCT00837928 | Metastatic Canc... Unspecified Adu... | bendamustine laboratory biom... Surgical Resect... Stereotactic bo... | 18 Years - | Ohio State University Comprehensive Cancer Center | |
| Temozolomide and Radiation Therapy in Treating Patients With Stage IV Malignant Melanoma With Measurable and Unresectable Cancer of the Central Nervous System | NCT00068666 | Melanoma (Skin) Metastatic Canc... | temozolomide radiation thera... | 18 Years - | Alliance for Clinical Trials in Oncology | |
| Carmustine Implants in Treating Patients With Brain Metastases | NCT00003878 | Metastatic Canc... Unspecified Adu... | polifeprosan 20... conventional su... | 18 Years - | National Cancer Institute (NCI) | |
| Tamoxifen, Carboplatin, and Topotecan in Treating Patients With CNS Metastases or Recurrent Brain or Spinal Cord Tumors | NCT00541138 | Brain and Centr... Metastatic Canc... Unspecified Adu... | carboplatin tamoxifen citra... topotecan hydro... pharmacological... | 18 Years - | City of Hope Medical Center | |
| Stereotactic Radiosurgery in Treating Patients With Large Brain Metastases | NCT01843413 | Tumors Metastat... Unspecified Adu... | stereotactic ra... quality-of-life... cognitive asses... | 18 Years - | Case Comprehensive Cancer Center | |
| Radiation Therapy With or Without RSR13 in Treating Patients With Brain Metastases | NCT00005887 | Metastatic Canc... | efaproxiral radiation thera... | 18 Years - 120 Years | Spectrum Pharmaceuticals, Inc | |
| Stereotactic Radiation Therapy in Treating Patients With Brain Metastases | NCT00006259 | Metastatic Canc... | stereotactic ra... | 18 Years - 120 Years | Case Comprehensive Cancer Center | |
| Radiolabeled Monoclonal Antibody Therapy in Treating Patients With Primary or Metastatic Brain Tumors | NCT00003461 | Brain and Centr... Metastatic Canc... Neuroblastoma | surgical proced... astatine At 211... | 18 Years - | Duke University | |
| Melatonin and Radiation Therapy in Treating Patients With Brain Metastases | NCT00031967 | Metastatic Canc... Radiation Toxic... Unspecified Adu... | therapeutic mel... radiation thera... | 0 Years - 120 Years | Radiation Therapy Oncology Group | |
| Melatonin and Radiation Therapy in Treating Patients With Brain Metastases | NCT00031967 | Metastatic Canc... Radiation Toxic... Unspecified Adu... | therapeutic mel... radiation thera... | 0 Years - 120 Years | Radiation Therapy Oncology Group | |
| Cediranib Maleate and Whole Brain Radiation Therapy in Patients With Brain Metastases From Non-Small Cell Lung Cancer | NCT00937482 | Male Breast Can... Stage IV Breast... Stage IV Melano... Stage IV Non-sm... Stage IV Renal ... Stage IVA Colon... Stage IVA Recta... Stage IVB Colon... Stage IVB Recta... Tumors Metastat... | cediranib malea... whole-brain rad... | 18 Years - | National Cancer Institute (NCI) | |
| Sunitinib in Treating Patients With Brain Metastases Caused by Kidney Cancer or Melanoma | NCT00462982 | Kidney Cancer Melanoma (Skin) Metastatic Canc... | sunitinib malat... | 18 Years - 120 Years | Memorial Sloan Kettering Cancer Center | |
| Magnetic Resonance Imaging for the Early Detection of CNS Metastases in Women With Stage IV Breast Cancer | NCT00398437 | Breast Cancer Metastatic Canc... | trastuzumab chemotherapy magnetic resona... | 18 Years - | National Cancer Institute (NCI) | |
| WBRT & Erlotinib in Advanced NSCLC and Brain Metastases | NCT00554775 | Lung Cancer Metastatic Canc... | erlotinib hydro... placebo | 18 Years - | University College, London | |
| Trastuzumab Plus R115777 in Treating Patients With Advanced or Metastatic Cancer | NCT00005842 | Cancer | trastuzumab tipifarnib | 18 Years - | National Cancer Institute (NCI) | |
| Monoclonal Antibody Therapy in Treating Patients With Primary or Metastatic Melanoma or Brain Tumors | NCT00002754 | Brain and Centr... Melanoma (Skin) Metastatic Canc... | monoclonal anti... | 3 Years - | Duke University | |
| Temozolomide With or Without Radiation Therapy to the Brain in Treating Patients With Stage IV Melanoma That Is Metastatic to the Brain | NCT00020839 | Melanoma (Skin) Metastatic Canc... | temozolomide radiation thera... | 18 Years - | European Organisation for Research and Treatment of Cancer - EORTC | |
| Lapatinib in Treating Brain Metastases in Patients With Stage IV Breast Cancer and Brain Metastases | NCT00098605 | Central Nervous... HER2-positive B... Male Breast Can... Recurrent Breas... Stage IV Breast... Tumors Metastat... | lapatinib ditos... laboratory biom... quality-of-life... questionnaire a... | 18 Years - | National Cancer Institute (NCI) | |
| Whole-Brain Radiation Therapy and Pemetrexed in Treating Patients With Brain Metastases From Non-Small Cell Lung Cancer | NCT00280748 | Lung Cancer Metastatic Canc... | pemetrexed diso... radiation thera... | 18 Years - | UNC Lineberger Comprehensive Cancer Center | |
| Bafetinib in Treating Patients With Recurrent High-Grade Glioma or Brain Metastases | NCT01234740 | Adult Anaplasti... Adult Anaplasti... Adult Anaplasti... Adult Giant Cel... Adult Glioblast... Adult Gliosarco... Adult Mixed Gli... Recurrent Adult... Tumors Metastat... Adult Anaplasti... | bafetinib microdialysis pharmacological... liquid chromato... mass spectromet... laboratory biom... protein express... western blottin... immunohistochem... therapeutic con... | 18 Years - | City of Hope Medical Center | |
| Radiation Therapy Plus Gadolinium Texaphyrin in Treating Patients With Brain Metastases | NCT00003563 | Metastatic Canc... | WBRT MGd | 18 Years - | Pharmacyclics LLC. | |
| Bafetinib in Treating Patients With Recurrent High-Grade Glioma or Brain Metastases | NCT01234740 | Adult Anaplasti... Adult Anaplasti... Adult Anaplasti... Adult Giant Cel... Adult Glioblast... Adult Gliosarco... Adult Mixed Gli... Recurrent Adult... Tumors Metastat... Adult Anaplasti... | bafetinib microdialysis pharmacological... liquid chromato... mass spectromet... laboratory biom... protein express... western blottin... immunohistochem... therapeutic con... | 18 Years - | City of Hope Medical Center | |
| Radiation Therapy in Treating Patients Who Are Undergoing Surgery to Remove a Metastatic Brain Tumor | NCT00107367 | Metastatic Canc... | conventional su... intraoperative ... | 18 Years - | National Cancer Institute (NCI) | |
| Phase 2 Etirinotecan Pegol in Refractory Brain Metastases & Advanced Lung Cancer / Metastatic Breast Cancer | NCT02312622 | Stage IV Non-sm... Recurrent Non-s... Extensive-stage... Recurrent Small... Tumors Metastat... Metastatic Brea... | Pegylated Irino... | 18 Years - | Stanford University | |
| Radiation Therapy With or Without Temozolomide in Treating Women With Brain Metastases and Breast Cancer | NCT00875355 | Breast Cancer Metastatic Canc... | temozolomide radiation thera... | 18 Years - | National Cancer Institute (NCI) | |
| Riluzole and Whole-Brain Radiation Therapy in Treating Patients With Brain Metastases | NCT01018836 | Metastatic Canc... Unspecified Adu... | riluzole whole-brain rad... | 18 Years - | Rutgers, The State University of New Jersey | |
| Radiation Therapy in Treating Patients Who Are Undergoing Surgery to Remove a Metastatic Brain Tumor | NCT00107367 | Metastatic Canc... | conventional su... intraoperative ... | 18 Years - | National Cancer Institute (NCI) | |
| Radiation Therapy Following Surgery to Remove Brain Metastases | NCT00003320 | Metastatic Canc... | surgical proced... radiation thera... stereotactic ra... | 18 Years - | Jonsson Comprehensive Cancer Center | |
| Carmustine Followed By Surgery in Treating Patients With Recurrent Supratentorial Malignant Glioma or Metastatic Brain Neoplasm | NCT00009854 | Brain and Centr... Metastatic Canc... | carmustine in e... conventional su... | 18 Years - 75 Years | National Cancer Institute (NCI) | |
| Dexamethasone and Supportive Care With or Without Whole-Brain Radiation Therapy in Treating Patients With Non-Small Cell Lung Cancer That Has Spread to the Brain and Cannot Be Removed By Surgery | NCT00403065 | Lung Cancer Metastatic Canc... | dexamethasone quality-of-life... radiation thera... | 18 Years - | National Cancer Institute (NCI) | |
| 11C Topotecan PET Imaging | NCT00253461 | Lung Cancer Metastatic Canc... Ovarian Cancer Unspecified Adu... | computed tomogr... positron emissi... 11C topotecan fludeoxyglucose... | 18 Years - | Case Comprehensive Cancer Center | |
| Radiosurgery With or Without Whole-Brain Radiation Therapy in Treating Patients With Brain Metastases | NCT00030628 | Metastatic Canc... | radiation thera... surgery WBRT | 18 Years - | Alliance for Clinical Trials in Oncology | |
| Pemetrexed Disodium in Treating Patients With Recurrent Malignant Gliomas, Primary CNS Lymphoma, or Brain Metastases | NCT00276783 | Brain and Centr... Lymphoma Metastatic Canc... | pemetrexed | 18 Years - 120 Years | Northwestern University | |
| Neoadjuvant Radiosurgery for Resectable Brain Metastases: Phase I/II Study | NCT01891318 | Tumors Metastat... | radiosurgery therapeutic con... quality-of-life... | 18 Years - | Case Comprehensive Cancer Center | |
| Voxel Based Diffusion Tensor Imaging in Predicting Response in Patients With Brain Metastases Undergoing Whole Brain Radiation Therapy or Stereotactic Radiosurgery | NCT02277561 | Tumors Metastat... Unspecified Adu... | diffusion tenso... whole-brain rad... stereotactic ra... contrast-enhanc... diffusion-weigh... | 19 Years - | Albert Einstein College of Medicine | |
| Temozolomide and Radiation Therapy in Treating Patients With Brain Metastasis Secondary to Non-Small Cell Lung Cancer | NCT00080938 | Lung Cancer Metastatic Canc... | Temozolomide Radiation thera... | 18 Years - | Eastern Cooperative Oncology Group | |
| Phase I Study of Ipilimumab Combined With Whole Brain Radiation Therapy or Radiosurgery for Melanoma | NCT01703507 | Recurrent Melan... Stage IV Melano... Tumors Metastat... | Ipilimumab Whole-Brain Rad... Stereotactic Ra... | 18 Years - | Thomas Jefferson University | |
| Liposomal Cytarabine and High-Dose Methotrexate in Treating Patients With Central Nervous System Metastases From Breast Cancer | NCT00992602 | Central Nervous... Leptomeningeal ... Recurrent Breas... Stage IV Breast... Tumors Metastat... | methotrexate liposomal cytar... quality-of-life... laboratory biom... | 18 Years - | University of Washington | |
| Icotinib Combined With Whole Brain Radiotherapy in Treating Multiple Brain Metastases From Non-Small Cell Lung Cancer | NCT01514877 | Lung Cancer Metastatic Canc... | Icotinib | 18 Years - 75 Years | Zhejiang Cancer Hospital | |
| Radiation Therapy Plus Gadolinium Texaphyrin in Treating Patients With Brain Metastases | NCT00003563 | Metastatic Canc... | WBRT MGd | 18 Years - | Pharmacyclics LLC. | |
| Acute Side Effects in Patients Who Are Undergoing Stereotactic Radiosurgery for Brain Tumors or Other Brain Disorders | NCT00255671 | Brain and Centr... Metastatic Canc... Radiation Toxic... | Questionnaire | 18 Years - | Case Comprehensive Cancer Center | |
| Sorafenib Tosylate and Stereotactic Radiosurgery in Treating Patients With Brain Metastases | NCT01276210 | Tumors Metastat... | sorafenib tosyl... stereotactic ra... laboratory biom... | 18 Years - | Vanderbilt-Ingram Cancer Center | |
| Tamoxifen, Carboplatin, and Topotecan in Treating Patients With CNS Metastases or Recurrent Brain or Spinal Cord Tumors | NCT00541138 | Brain and Centr... Metastatic Canc... Unspecified Adu... | carboplatin tamoxifen citra... topotecan hydro... pharmacological... | 18 Years - | City of Hope Medical Center | |
| Everolimus and Whole-Brain Radiation Therapy in Treating Patients With Brain Metastasis From Non-Small Cell Lung Cancer | NCT00892801 | Lung Cancer Metastatic Canc... | RAD001 whole-brain rad... | 18 Years - | Vanderbilt-Ingram Cancer Center | |
| Stereotactic Radiosurgery in Treating Patients With Large Brain Metastases | NCT01843413 | Tumors Metastat... Unspecified Adu... | stereotactic ra... quality-of-life... cognitive asses... | 18 Years - | Case Comprehensive Cancer Center | |
| Boron Neutron Capture Therapy in Treating Patients With Glioblastoma Multiforme or Melanoma Metastatic to the Brain | NCT00039572 | Brain and Centr... Melanoma (Skin) Metastatic Canc... | boronophenylala... | 18 Years - | National Cancer Institute (NCI) | |
| S9903: Whole Brain Radiotherapy Followed By Stereotactic Radiosurgery for Limited Malignant Melanoma Brain Metastases | NCT00003911 | Melanoma (Skin) Metastatic Canc... | stereotactic ra... | - | SWOG Cancer Research Network | |
| Sorafenib in Treating Patients With Kidney Cancer That Has Spread to the Brain | NCT00301847 | Kidney Cancer Metastatic Canc... | sorafenib tosyl... | 18 Years - | National Cancer Institute (NCI) | |
| Boron Neutron Capture Therapy in Treating Patients With Glioblastoma Multiforme or Melanoma Metastatic to the Brain | NCT00039572 | Brain and Centr... Melanoma (Skin) Metastatic Canc... | boronophenylala... | 18 Years - | National Cancer Institute (NCI) | |
| Quantitative MRI in Assessing Disease in Patients With Brain Tumors | NCT02269111 | Tumors Metastat... Unspecified Adu... | diffusion-weigh... chemical exchan... dynamic contras... dynamic suscept... | 18 Years - | Vanderbilt-Ingram Cancer Center | |
| Epothilone B in Treating Patients With CNS Metastases From Breast Cancer | NCT00450866 | Breast Cancer Metastatic Canc... | epothilone B | 18 Years - | Case Comprehensive Cancer Center | |
| Temozolomide With or Without Radiation Therapy to the Brain in Treating Patients With Stage IV Melanoma That Is Metastatic to the Brain | NCT00020839 | Melanoma (Skin) Metastatic Canc... | temozolomide radiation thera... | 18 Years - | European Organisation for Research and Treatment of Cancer - EORTC | |
| Irinotecan and Temozolomide in Treating Patients With Breast Cancer Who Have Received Previous Treatment for Brain Metastases | NCT00617539 | Breast Cancer Metastatic Canc... | irinotecan hydr... temozolomide | 18 Years - 120 Years | University of California, San Francisco | |
| Vemurafenib Combined With Whole Brain Radiation Therapy or Radiosurgery in Patients With BRAF Mutation-Positive Melanoma and Brain Metastases | NCT02145910 | Recurrent Melan... Stage IV Melano... Tumors Metastat... | Vemurafenib Whole-brain rad... Radiosurgery (S... | 18 Years - | Thomas Jefferson University | |
| WBRT & Erlotinib in Advanced NSCLC and Brain Metastases | NCT00554775 | Lung Cancer Metastatic Canc... | erlotinib hydro... placebo | 18 Years - | University College, London | |
| Radiolabeled Monoclonal Antibody Therapy in Treating Patients With Primary or Metastatic Brain Cancers | NCT00002752 | Brain and Centr... Metastatic Canc... | iodine I 131 mo... | 3 Years - | Duke University | |
| Temozolomide With or Without Radiation Therapy to the Brain in Treating Patients With Stage IV Melanoma That Is Metastatic to the Brain | NCT00020839 | Melanoma (Skin) Metastatic Canc... | temozolomide radiation thera... | 18 Years - | European Organisation for Research and Treatment of Cancer - EORTC |
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