Spots Global Cancer Trial Database for surgical procedure
Every month we try and update this database with for surgical procedure cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.
The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
| Study title | NCT ID | Conditions | Interventions | Eligibility | Organization | Link |
|---|---|---|---|---|---|---|
| Carboplatin Chemotherapy Before Surgery for People With High-Risk Prostate Cancer and an Inherited BRCA1 or BRCA2 Gene Mutation | NCT05806515 | Prostate Adenoc... Stage IIIB Pros... Stage IIIC Pros... | Biospecimen Col... Carboplatin Chest Radiograp... Computed Tomogr... Magnetic Resona... PSMA PET Scan Surgical Proced... | 18 Years - | SWOG Cancer Research Network | |
| Radiation Therapy With or Without Radiosurgery in Treating Patients With Brain Metastases | NCT00002708 | Metastatic Canc... | surgical proced... radiation thera... stereotactic ra... | 18 Years - | Radiation Therapy Oncology Group | |
| Chemotherapy Plus Radiation Therapy in Treating Patients With Head and Neck Cancer | NCT00002951 | Esophageal Canc... Head and Neck C... | fluorouracil hydroxyurea surgical proced... radiation thera... | - | University of Chicago | |
| Fluorescence Image Guided Surgery Followed by Intraoperative Photodynamic Therapy for Improving Local Tumor Control in Patients With Locally Advanced or Recurrent Colorectal Cancer | NCT06307548 | Locally Advance... Recurrent Color... Stage III Color... | Aminolevulinic ... Biospecimen Col... Computed Tomogr... Fluorescence-Gu... Magnetic Resona... Photodynamic Th... Surgical Proced... | 18 Years - | Roswell Park Cancer Institute | |
| Anti-Lag-3 (Relatlinib) and Anti-PD-1 Blockade (Nivolumab) Versus Standard of Care (Lomustine) for the Treatment of Patients With Recurrent Glioblastoma | NCT06325683 | Recurrent Gliob... | Biopsy Biospecimen Col... Lomustine Magnetic Resona... Nivolumab Relatlimab Surgical Proced... | 18 Years - | National Cancer Institute (NCI) | |
| Surgery With or Without Chemotherapy and Radiation Therapy in Treating Patients With Cancer of the Esophagus | NCT00003118 | Esophageal Canc... | cisplatin fluorouracil surgical proced... radiation thera... | 18 Years - | Alliance for Clinical Trials in Oncology | |
| Radiolabeled Monoclonal Antibody Therapy in Treating Patients With Primary or Metastatic Brain Tumors | NCT00003461 | Brain and Centr... Metastatic Canc... Neuroblastoma | surgical proced... astatine At 211... | 18 Years - | Duke University | |
| WP1066 and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma | NCT05879250 | Glioblastoma, I... MGMT-Unmethylat... | Biospecimen Col... Magnetic Resona... Radiation Thera... STAT3 Inhibitor... Surgical Proced... | 18 Years - | Northwestern University | |
| Testing the Role of FDG-PET/CT to Predict Response to Therapy Prior to Surgery for HER2-positive Breast Cancer, The DIRECT Trial | NCT05710328 | Anatomic Stage ... Anatomic Stage ... HER2-Positive B... Invasive Breast... | Chemotherapy Computed Tomogr... Fludeoxyglucose... Positron Emissi... Surgical Proced... | 18 Years - | Eastern Cooperative Oncology Group | |
| Combination Chemotherapy and Surgery in Treating Patients With Newly Diagnosed Metastatic Osteosarcoma | NCT00003776 | Sarcoma | filgrastim cisplatin doxorubicin hyd... ifosfamide leucovorin calc... methotrexate trimetrexate gl... surgical proced... | - 30 Years | Memorial Sloan Kettering Cancer Center | |
| Combination Chemotherapy, Radiation Therapy and Surgery in Treating Patients With Cancer of the Esophagus | NCT00003087 | Esophageal Canc... | cisplatin paclitaxel surgical proced... radiation thera... | 18 Years - | Memorial Sloan Kettering Cancer Center | |
| IL-4(38-37)-PE38KDEL Immunotoxin in Treating Patients With Recurrent Malignant Astrocytoma | NCT00003842 | Brain and Centr... | interleukin-4 P... isolated perfus... surgical proced... | 18 Years - | National Cancer Institute (NCI) | |
| Doxorubicin and Paclitaxel in Treating Women With Locally Advanced Breast Cancer | NCT00003035 | Breast Cancer | filgrastim doxorubicin hyd... paclitaxel tamoxifen citra... surgical proced... radiation thera... | 18 Years - | Georgetown University | |
| Transurethral Resection and Combination Chemotherapy in Treating Patients With Stage II or Stage III Bladder Cancer | NCT00003640 | Bladder Cancer | filgrastim cisplatin doxorubicin hyd... methotrexate vinblastine sul... surgical proced... radiation thera... | - | European Organisation for Research and Treatment of Cancer - EORTC | |
| Motexafin Gadolinium With MRI-Guided Surgery in Treating Patients With High-Grade Gliomas | NCT00003410 | Brain and Centr... | motexafin gadol... magnetic resona... surgical proced... | 18 Years - | National Cancer Institute (NCI) | |
| Surgery, Radiation Therapy, and Combination Chemotherapy in Treating Patients With Recurrent Head and Neck Cancer | NCT00003777 | Head and Neck C... | amifostine trih... cisplatin fluorouracil surgical proced... radiation thera... | 18 Years - 120 Years | Abramson Cancer Center at Penn Medicine | |
| Testing the Combination of Anti-cancer Drugs Tiragolumab and Atezolizumab to Improve Outcomes for Patients With Recurrent Glioblastoma | NCT06328036 | Recurrent Gliob... | Atezolizumab Biospecimen Col... Magnetic Resona... Surgical Proced... Tiragolumab | 18 Years - | National Cancer Institute (NCI) | |
| Biological Therapy Following Surgery in Treating Patients With Stage III or Stage IV Melanoma | NCT00004022 | Melanoma (Skin) | aldesleukin autologous tumo... muromonab-CD3 therapeutic aut... surgical proced... | 18 Years - | Barbara Ann Karmanos Cancer Institute | |
| Radiation Therapy Plus Paclitaxel in Treating Patients With Stage IIB or Stage III Breast Cancer | NCT00003050 | Breast Cancer | cyclophosphamid... doxorubicin hyd... paclitaxel tamoxifen citra... surgical proced... radiation thera... | 18 Years - | University of Southern California | |
| Combination Chemotherapy, Radiation Therapy and Surgery in Treating Patients With Cancer of the Esophagus | NCT00003087 | Esophageal Canc... | cisplatin paclitaxel surgical proced... radiation thera... | 18 Years - | Memorial Sloan Kettering Cancer Center | |
| Tremelimumab and Durvalumab in Combination or Alone in Treating Patients With Recurrent Malignant Glioma | NCT02794883 | Malignant Gliom... Recurrent Gliob... | Durvalumab Laboratory Biom... Surgical Proced... Tremelimumab | 18 Years - | Northwestern University | |
| Radiolabeled Monoclonal Antibody Therapy in Treating Patients With Primary or Metastatic Brain Tumors | NCT00003461 | Brain and Centr... Metastatic Canc... Neuroblastoma | surgical proced... astatine At 211... | 18 Years - | Duke University | |
| A Study to Test the Addition of the Drug Cabozantinib to Chemotherapy in Patients With Newly Diagnosed Osteosarcoma | NCT05691478 | High Grade Oste... Localized Osteo... Metastatic Oste... Secondary Osteo... | Bone Scan Cabozantinib S-... Cisplatin Computed Tomogr... Doxorubicin Hyd... Magnetic Resona... Methotrexate Surgical Proced... X-Ray Imaging | - 40 Years | National Cancer Institute (NCI) | |
| Testing the Addition of Immunotherapy Before Surgery for Patients With Sarcomatoid Mesothelioma | NCT05647265 | Pleural Biphasi... Pleural Sarcoma... | Nivolumab Ipilimumab Surgical Proced... Computed Tomogr... Magnetic Resona... Positron Emissi... | 18 Years - | Alliance for Clinical Trials in Oncology | |
| Biological Therapy Plus Chemotherapy in Treating Patients With Metastatic or Recurrent Kidney Cancer | NCT00003585 | Kidney Cancer | aldesleukin recombinant int... fluorouracil isotretinoin surgical proced... | - | University of New Mexico | |
| Carmustine in Treating Adults With Recurrent Supratentorial Low-Grade Glioma | NCT00003467 | Brain and Centr... | carmustine polifeprosan 20... surgical proced... | 18 Years - | Duke University | |
| IL-4(38-37)-PE38KDEL Immunotoxin in Treating Patients With Recurrent Malignant Astrocytoma | NCT00003842 | Brain and Centr... | interleukin-4 P... isolated perfus... surgical proced... | 18 Years - | National Cancer Institute (NCI) | |
| Nelipepimut-S Plus GM-CSF Vaccine Therapy in Treating Patients With Breast Cancer | NCT02636582 | Breast Ductal C... | Laboratory Biom... Nelipepimut-S P... Sargramostim Surgical Proced... | 18 Years - | National Cancer Institute (NCI) | |
| Carmustine in Treating Adults With Recurrent Supratentorial Low-Grade Glioma | NCT00003467 | Brain and Centr... | carmustine polifeprosan 20... surgical proced... | 18 Years - | Duke University | |
| Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Advanced or Metastatic Cancer of the Esophagus | NCT00002984 | Esophageal Canc... | cisplatin fluorouracil paclitaxel surgical proced... radiation thera... | 18 Years - | UNC Lineberger Comprehensive Cancer Center | |
| Evaluating 111In Panitumumab for Nodal Staging in Head and Neck Cancer | NCT05901545 | Head and Neck S... Recurrent Head ... | Panitumumab Indium In 111 P... Single Photon E... Computed Tomogr... Surgical Proced... Imaging agent Intraoperative ... Near Infrared I... Electrocardiogr... Biospecimen Col... | 19 Years - | Vanderbilt-Ingram Cancer Center | |
| Infigratinib Before Surgery for the Treatment of Upper Tract Urothelial Cancer | NCT04228042 | Renal Pelvis an... | Infigratinib Quality-of-Life... Questionnaire A... Surgical Proced... | 18 Years - | M.D. Anderson Cancer Center | |
| Intraperitoneal Oxaliplatin and Fluorouracil for the Treatment of Patients With Peritoneal Metastases From Colorectal Cancer | NCT06269978 | Metastatic Colo... Metastatic Mali... Stage IV Colore... | Biopsy Biospecimen Col... Computed Tomogr... Diagnostic Lapa... Fluorouracil Magnetic Resona... Oxaliplatin Surgical Proced... | 18 Years - | Ohio State University Comprehensive Cancer Center | |
| Carmustine in Treating Adults With Recurrent Supratentorial Low-Grade Glioma | NCT00003467 | Brain and Centr... | carmustine polifeprosan 20... surgical proced... | 18 Years - | Duke University | |
| Radiation Therapy Following Surgery to Remove Brain Metastases | NCT00003320 | Metastatic Canc... | surgical proced... radiation thera... stereotactic ra... | 18 Years - | Jonsson Comprehensive Cancer Center | |
| Surgery in Treating Patients With Neuroblastoma | NCT00003122 | Neuroblastoma | surgical proced... | - 20 Years | National Cancer Institute (NCI) | |
| Identification of Sentinel Lymph Nodes With Methylene Blue and Isotope | NCT00314405 | Infiltrative Br... | Methylene blue ... Rhenium sulfure Surgical proced... Anatomo-patholo... | 18 Years - | University Hospital, Strasbourg, France | |
| Inhalational or Intravenous Anesthesia During Surgery for Patients With Colon Cancer, VIVA Study | NCT06017141 | Colon Adenocarc... | Biospecimen Col... Electronic Heal... Fentanyl Citrat... Propofol Questionnaire A... Sevoflurane Surgical Proced... | 18 Years - | University of Kansas Medical Center | |
| Combination Chemotherapy Followed by Surgery in Treating Patients With Non-small Cell Lung Cancer | NCT00003231 | Lung Cancer | cisplatin docetaxel surgical proced... radiation thera... | 18 Years - 75 Years | Swiss Group for Clinical Cancer Research | |
| Surgery and Radiation Therapy Compared With Chemotherapy and Radiation Therapy in Treating Patients With Stage III or Stage IV Head and Neck Cancer That Can Be Removed During Surgery | NCT00003576 | Head and Neck C... | cisplatin fluorouracil surgical proced... radiation thera... | - | National Cancer Institute (NCI) | |
| Biological Therapy Following Surgery and Radiation Therapy in Treating Patients With Primary or Recurrent Astrocytoma or Oligodendroglioma | NCT00004024 | Brain and Centr... | aldesleukin autologous tumo... muromonab-CD3 sargramostim therapeutic aut... surgical proced... radiation thera... | 18 Years - | Barbara Ann Karmanos Cancer Institute | |
| Identification of Sentinel Lymph Nodes With Methylene Blue and Isotope | NCT00314405 | Infiltrative Br... | Methylene blue ... Rhenium sulfure Surgical proced... Anatomo-patholo... | 18 Years - | University Hospital, Strasbourg, France | |
| Surgery in Treating Patients With Neuroblastoma | NCT00003122 | Neuroblastoma | surgical proced... | - 20 Years | National Cancer Institute (NCI) | |
| Internal Radiation Therapy Plus Carmustine Implants in Treating Patients With Recurrent or Refractory Malignant Glioma | NCT00003876 | Brain and Centr... | polifeprosan 20... surgical proced... iodine I 125 | 18 Years - | National Cancer Institute (NCI) | |
| A Study Evaluating Whether Pembrolizumab Alone or in Combination With CMP-001 Improves Efficacy in Patients With Operable Melanoma | NCT04708418 | Clinical Stage ... Melanoma of Unk... Pathologic Stag... Pathologic Stag... Pathologic Stag... Recurrent Cutan... | Biopsy Biospecimen Col... Computed Tomogr... Pembrolizumab Positron Emissi... Surgical Proced... VLP-encapsulate... | 18 Years - | National Cancer Institute (NCI) | |
| Radiation Therapy Plus Paclitaxel in Treating Patients With Stage IIB or Stage III Breast Cancer | NCT00003050 | Breast Cancer | cyclophosphamid... doxorubicin hyd... paclitaxel tamoxifen citra... surgical proced... radiation thera... | 18 Years - | University of Southern California | |
| Biological Therapy Following Surgery in Treating Patients With Stage III or Stage IV Melanoma | NCT00004022 | Melanoma (Skin) | aldesleukin autologous tumo... muromonab-CD3 therapeutic aut... surgical proced... | 18 Years - | Barbara Ann Karmanos Cancer Institute | |
| Combination Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Stage III or Stage IV Ovarian Epithelial Cancer | NCT00003413 | Ovarian Cancer | filgrastim carmustine cisplatin melphalan paclitaxel peripheral bloo... surgical proced... | 18 Years - 70 Years | University of Maryland, Baltimore | |
| Irinotecan in Treating Patients With Metastatic Colorectal Cancer | NCT00003544 | Colorectal Canc... | irinotecan hydr... surgical proced... | 18 Years - | Memorial Sloan Kettering Cancer Center | |
| Carboplatin Chemotherapy Before Surgery for People With High-Risk Prostate Cancer and an Inherited BRCA1 or BRCA2 Gene Mutation | NCT05806515 | Prostate Adenoc... Stage IIIB Pros... Stage IIIC Pros... | Biospecimen Col... Carboplatin Chest Radiograp... Computed Tomogr... Magnetic Resona... PSMA PET Scan Surgical Proced... | 18 Years - | SWOG Cancer Research Network | |
| An Imaging Agent (Fluorodopa F 18) With Positron Emission Tomography/Magnetic Resonance Imaging for Assessing Treatment Response in Patients With High-Grade Soft Tissue Sarcomas | NCT05560009 | Recurrent Soft ... Resectable Soft... Soft Tissue Sar... | Fluorodopa F 18 Magnetic Resona... Positron Emissi... Radiation Thera... Surgical Proced... | 18 Years - | Mayo Clinic | |
| Transurethral Resection and Combination Chemotherapy in Treating Patients With Stage II or Stage III Bladder Cancer | NCT00003640 | Bladder Cancer | filgrastim cisplatin doxorubicin hyd... methotrexate vinblastine sul... surgical proced... radiation thera... | - | European Organisation for Research and Treatment of Cancer - EORTC | |
| Testing the Combination of Anti-cancer Drugs Tiragolumab and Atezolizumab to Improve Outcomes for Patients With Recurrent Glioblastoma | NCT06328036 | Recurrent Gliob... | Atezolizumab Biospecimen Col... Magnetic Resona... Surgical Proced... Tiragolumab | 18 Years - | National Cancer Institute (NCI) | |
| Carboplatin Plus Paclitaxel or Docetaxel in Treating Patients With Ovarian Epithelial Cancer | NCT00003998 | Ovarian Cancer Primary Periton... | carboplatin docetaxel paclitaxel surgical proced... | 18 Years - | National Cancer Institute (NCI) | |
| A Study of Lower Radiotherapy Dose to Treat Children With CNS Germinoma | NCT06368817 | Central Nervous... Diabetes Insipi... Pineal Region G... Suprasellar Ger... | 3-Dimensional C... Biospecimen Col... Carboplatin Etoposide Intensity-Modul... Lumbar Puncture Magnetic Resona... Questionnaire A... Surgical Proced... | 3 Years - 30 Years | Children's Oncology Group | |
| Irinotecan in Treating Patients With Metastatic Colorectal Cancer | NCT00003544 | Colorectal Canc... | irinotecan hydr... surgical proced... | 18 Years - | Memorial Sloan Kettering Cancer Center | |
| Surgery With or Without Chemotherapy in Treating Patients With Stage IB Cervical Cancer | NCT00002536 | Cervical Cancer | cisplatin vincristine sul... surgical proced... radiation thera... | - | GOG Foundation | |
| Surgery Plus Radiation Therapy With or Without Chemotherapy in Treating Children With Primitive Neuroectodermal Tumors of the CNS | NCT00003859 | Brain and Centr... | carboplatin cyclophosphamid... etoposide vincristine sul... surgical proced... radiation thera... | 3 Years - 16 Years | National Cancer Institute (NCI) | |
| Combination Chemotherapy After Surgery in Treating Patients With Cancer of the Esophagus or Stomach | NCT00003237 | Esophageal Canc... Gastric Cancer | cisplatin paclitaxel surgical proced... | 18 Years - 120 Years | Eastern Cooperative Oncology Group | |
| Short Stitch Versus Traditional Suture for the Prevention of Incisional Hernia After Open Hepatectomy | NCT04982653 | Liver and Intra... Metastatic Mali... Primary Maligna... | Quality-of-Life... Surgical Proced... Surgical Proced... | 18 Years - | M.D. Anderson Cancer Center | |
| A Study of Lower Radiotherapy Dose to Treat Children With CNS Germinoma | NCT06368817 | Central Nervous... Diabetes Insipi... Pineal Region G... Suprasellar Ger... | 3-Dimensional C... Biospecimen Col... Carboplatin Etoposide Intensity-Modul... Lumbar Puncture Magnetic Resona... Questionnaire A... Surgical Proced... | 3 Years - 30 Years | Children's Oncology Group | |
| Shorter Chemo-Immunotherapy Without Anthracycline Drugs for Early-Stage Triple Negative Breast Cancer | NCT05929768 | Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Early Stage Tri... | Biospecimen Col... Carboplatin Cyclophosphamid... Docetaxel Doxorubicin Paclitaxel Pembrolizumab Quality-of-Life... Questionnaire A... Surgical Proced... | 18 Years - | SWOG Cancer Research Network | |
| Radiation Therapy With or Without Radiosurgery in Treating Patients With Brain Metastases | NCT00002708 | Metastatic Canc... | surgical proced... radiation thera... stereotactic ra... | 18 Years - | Radiation Therapy Oncology Group | |
| Infigratinib Before Surgery for the Treatment of Upper Tract Urothelial Cancer | NCT04228042 | Renal Pelvis an... | Infigratinib Quality-of-Life... Questionnaire A... Surgical Proced... | 18 Years - | M.D. Anderson Cancer Center | |
| Surgery in Treating Patients With Neuroblastoma | NCT00003122 | Neuroblastoma | surgical proced... | - 20 Years | National Cancer Institute (NCI) | |
| Surgery Plus Radiation Therapy With or Without Chemotherapy in Treating Children With Primitive Neuroectodermal Tumors of the CNS | NCT00003859 | Brain and Centr... | carboplatin cyclophosphamid... etoposide vincristine sul... surgical proced... radiation thera... | 3 Years - 16 Years | National Cancer Institute (NCI) | |
| Surgery With or Without Chemotherapy in Treating Patients With Stage IB Cervical Cancer | NCT00002536 | Cervical Cancer | cisplatin vincristine sul... surgical proced... radiation thera... | - | GOG Foundation | |
| Surgery, Radiation Therapy, and Chemotherapy With or Without Photodynamic Therapy in Treating Patients With Newly Diagnosed or Recurrent Malignant Supratentorial Gliomas | NCT00003788 | Brain and Centr... | carmustine lomustine porfimer sodium procarbazine hy... neoadjuvant the... surgical proced... radiation thera... | 18 Years - | National Cancer Institute (NCI) | |
| Combination Chemotherapy Followed by Surgery in Treating Patients With Stage IIIA Non-small Cell Lung Cancer | NCT00003111 | Lung Cancer | carboplatin cisplatin irinotecan hydr... paclitaxel neoadjuvant the... surgical proced... radiation thera... | 18 Years - | Yale University | |
| Carboplatin Plus Paclitaxel or Docetaxel in Treating Patients With Ovarian Epithelial Cancer | NCT00003998 | Ovarian Cancer Primary Periton... | carboplatin docetaxel paclitaxel surgical proced... | 18 Years - | National Cancer Institute (NCI) | |
| Combination Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Stage III or Stage IV Ovarian Epithelial Cancer | NCT00003413 | Ovarian Cancer | filgrastim carmustine cisplatin melphalan paclitaxel peripheral bloo... surgical proced... | 18 Years - 70 Years | University of Maryland, Baltimore | |
| WP1066 and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma | NCT05879250 | Glioblastoma, I... MGMT-Unmethylat... | Biospecimen Col... Magnetic Resona... Radiation Thera... STAT3 Inhibitor... Surgical Proced... | 18 Years - | Northwestern University | |
| Neoadjuvant Therapy for the Treatment of Gastroesophageal Junction and Gastric Cancers | NCT05296005 | Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Gastric Adenoca... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... | Capecitabine Docetaxel Fluorouracil Leucovorin Oxaliplatin Radiation Thera... Surgical Proced... | 18 Years - | Ohio State University Comprehensive Cancer Center | |
| Doxorubicin and Paclitaxel in Treating Women With Locally Advanced Breast Cancer | NCT00003035 | Breast Cancer | filgrastim doxorubicin hyd... paclitaxel tamoxifen citra... surgical proced... radiation thera... | 18 Years - | Georgetown University | |
| Radiolabeled Monoclonal Antibody Therapy After Radiation Therapy in Treating Patients With Primary Brain Tumors | NCT00003484 | Brain and Centr... Neuroblastoma | carmustine irinotecan hydr... surgical proced... iodine I 131 mo... | 18 Years - | Duke University | |
| Tremelimumab and Durvalumab in Combination or Alone in Treating Patients With Recurrent Malignant Glioma | NCT02794883 | Malignant Gliom... Recurrent Gliob... | Durvalumab Laboratory Biom... Surgical Proced... Tremelimumab | 18 Years - | Northwestern University |
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