Spots Global Cancer Trial Database for brain metastases, adult
Every month we try and update this database with for brain metastases, adult cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.
The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
Study title | NCT ID | Conditions | Interventions | Eligibility | Organization | Link |
---|---|---|---|---|---|---|
A Study of 68Ga-PSMA-11 PET Scans in People With Brain Tumors | NCT06209567 | High-grade Glio... Brain Metastase... Brain Metastase... | 68Ga-PSMA-11 PE... | 18 Years - | Memorial Sloan Kettering Cancer Center | |
A Study of 68Ga-PSMA-11 PET Scans in People With Brain Tumors | NCT06209567 | High-grade Glio... Brain Metastase... Brain Metastase... | 68Ga-PSMA-11 PE... | 18 Years - | Memorial Sloan Kettering Cancer Center | |
Exploring Compensation to Maintain Cognitive Function in Adults Newly Diagnosed With Brain Cancer | NCT04075370 | Primary Brain T... Brain Metastase... | Neuropsychologi... | 30 Years - 65 Years | Duke University | |
Nivolumab and Ipilimumab Plus Chemotherapy for Patients With Stage IV Lung Cancer With Brain Metastases | NCT05012254 | Non Small Cell ... Brain Metastase... Lung Cancer | Ipilimumab Nivolumab Carboplatin Cisplatin Paclitaxel Pemetrexed | 18 Years - | Fundación GECP | |
Keto-Brain:Investigating the Use of Ketogenic Diets in Brain Metastases | NCT05428852 | Brain Metastase... | Laboratory Biom... Neurocognitive ... Questionnaire A... Fitbit Dietary Interve... | 18 Years - 75 Years | Ohio State University Comprehensive Cancer Center | |
Circulating Biomarkers Repository in Adults Diagnosed With Primary and Metastatic Brain Tumors | NCT05480644 | Brain Tumor, Pr... Brain Metastase... | 18 Years - | Duke University | ||
Hypofractionated Brain Radiationcavity | NCT03561896 | Brain Metastase... Cancer Brain | IGRT SRS | 18 Years - | Oncology Institute of Southern Switzerland | |
A Phase II Study of Pre-Op SRS Followed by Surgical Resection for Brain Metastases | NCT05341739 | Brain Metastase... | Pre-operative S... | 18 Years - | Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute) | |
Trial of Preoperative Radiosurgery Versus Postoperative Stereotactic Radiotherapy for Resectable Brain Metastases | NCT05124236 | Brain Metastase... | preoperative ra... postoperative h... | 18 Years - | Kantonsspital Aarau | |
Safety Study of Pritumumab in Brain Cancer | NCT04396717 | Malignant Prima... Brain Metastase... | Pritumumab | 18 Years - | Nascent Biotech | |
Safety Study of Pritumumab in Brain Cancer | NCT04396717 | Malignant Prima... Brain Metastase... | Pritumumab | 18 Years - | Nascent Biotech | |
a Feasibility Study of iHD-SRT for BM | NCT06231186 | Brain Metastase... Stereotactic Ra... | iHD-SRT | - | Ruijin Hospital | |
Comparing Single vs Multiple Dose Radiation for Cancer Patients With Brain Metastasis and Receiving Immunotherapy | NCT05703269 | NSCLC Renal Cell Carc... Breast Carcinom... Melanoma Brain Metastase... Non-small Cell ... SCLC Small-cell Lung... | single fraction... fractionated st... | 18 Years - | Wake Forest University Health Sciences | |
Neoadjuvant Immunotherapy in Brain Metastases | NCT04434560 | Brain Metastase... | Nivolumab Ipilimumab | 18 Years - | Duke University | |
Local Ablative Therapy for Patients With Multiple (4-10) Brain Metastases | NCT04397978 | Brain Metastase... | Stereotactic ra... | 18 Years - | Universitaire Ziekenhuizen KU Leuven | |
Survivorship Study of Cancer Patients Who Received Cranial Radiation Therapy | NCT04567251 | Brain Metastase... Primary Brain T... Lung Cancer | 18 Years - | Duke University | ||
Assess Use of 18F-Fluciclovine for Patients With Large Brain Metastases Treated With Staged Stereotactic Radiosurgery | NCT04689048 | Brain Metastase... Brain Metastase... Brain Cancer | 18F fluciclovin... | 18 Years - | Baptist Health South Florida | |
Stereotactic Radiotherapy Management of Brain Metastases: the Value of a Longitudinal Multimodal Approach (POSTPONE) | NCT06029140 | Brain Metastase... | 18 Years - | University Hospital, Brest | ||
The Cohort for Patient-reported Outcomes, Imaging and Trial Inclusion in Metastatic BRAin Disease (COIMBRA) | NCT05267158 | Brain Metastase... Brain Neoplasms... | 18 Years - | UMC Utrecht | ||
Circulating Biomarkers Repository in Adults Diagnosed With Primary and Metastatic Brain Tumors | NCT05480644 | Brain Tumor, Pr... Brain Metastase... | 18 Years - | Duke University | ||
Focal Intraoperative Radiotherapy of Brain Metastases | NCT03789149 | Brain Metastase... Central Nervous... | Intraoperative ... | 18 Years - | AC Camargo Cancer Center | |
The Cohort for Patient-reported Outcomes, Imaging and Trial Inclusion in Metastatic BRAin Disease (COIMBRA) | NCT05267158 | Brain Metastase... Brain Neoplasms... | 18 Years - | UMC Utrecht | ||
Preoperative vs Postoperative Hypofractionated Radiosurgery for Patients With Large Brain Metastases | NCT05545007 | Brain Metastase... | Hypofractionate... Brain metastase... | 18 Years - | Istituto Clinico Humanitas | |
JDQ443 for KRAS G12C NSCLC Brain Metastases | NCT05999357 | Non Small Cell ... Brain Metastase... KRAS G12C | JDQ443 | 18 Years - | Maastricht University Medical Center | |
Combining Radiosurgery and Nivolumab in the Treatment of Brain Metastases | NCT02978404 | Clear-Cell Meta... Non Small Cell ... Brain Metastase... Small Cell Lung... Melanoma | Nivolumab Radiosurgery | 18 Years - | Centre hospitalier de l'Université de Montréal (CHUM) | |
Focal Intraoperative Radiotherapy of Brain Metastases | NCT03789149 | Brain Metastase... Central Nervous... | Intraoperative ... | 18 Years - | AC Camargo Cancer Center | |
Combining Radiosurgery and Nivolumab in the Treatment of Brain Metastases | NCT02978404 | Clear-Cell Meta... Non Small Cell ... Brain Metastase... Small Cell Lung... Melanoma | Nivolumab Radiosurgery | 18 Years - | Centre hospitalier de l'Université de Montréal (CHUM) | |
A Phase II Study of Pre-Op SRS Followed by Surgical Resection for Brain Metastases | NCT05341739 | Brain Metastase... | Pre-operative S... | 18 Years - | Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute) | |
Re-TREAT: Re-irradiation for Relapsed Brain Metastases | NCT05126875 | Cancer Brain Metastase... | Repeated stereo... | 18 Years - | Rigshospitalet, Denmark | |
a Feasibility Study of iHD-SRT for BM | NCT06231186 | Brain Metastase... Stereotactic Ra... | iHD-SRT | - | Ruijin Hospital | |
RAPid SimPLE Targeted Radiation Treatment for Brain Metastases | NCT05050929 | Brain Metastase... | Targeting All B... | 18 Years - 100 Years | British Columbia Cancer Agency | |
Glutamate Excitotoxicity in Brain Metastases From Lung, Breast and Melanoma Treated With Stereotactic Radiosurgery | NCT04785521 | Brain Metastase... | Stereotactic ra... Blood samples | 18 Years - | IRCCS San Raffaele | |
Prospective Double Arm Randomized Trial: WBRT Alone and WBRT Plus Silibinin | NCT05793489 | Brain Metastase... | Silibinin | 18 Years - | Istituto Clinico Humanitas | |
Effect of Azeliragon Combined With Stereotactic Radiation Therapy in Patients With Brain Metastases | NCT05789589 | Cancer Metastasis Metastatic Canc... Brain Metastase... Brain Metastase... | Azeliragon Stereotactic ra... Corticosteroid | 18 Years - | Baptist Health South Florida | |
RAPid SimPLE Targeted Radiation Treatment for Brain Metastases | NCT05050929 | Brain Metastase... | Targeting All B... | 18 Years - 100 Years | British Columbia Cancer Agency | |
18F-Fluciclovine PET Amino Acid Evaluation of Brain Metastasis Treated With Stereotactic Radiosurgery | NCT06048094 | Brain Metastase... Brain Metastase... Brain Cancer | 18F fluciclovin... | 18 Years - | Baptist Health South Florida | |
The Cohort for Patient-reported Outcomes, Imaging and Trial Inclusion in Metastatic BRAin Disease (COIMBRA) | NCT05267158 | Brain Metastase... Brain Neoplasms... | 18 Years - | UMC Utrecht | ||
Stereotactic Radiotherapy of the Resection Cavity of Brain Metastases vs. Post-operative Whole-brain Radiotherapy | NCT03285932 | Brain Metastase... | post-operative ... Whole brain rad... | 18 Years - | University Hospital Heidelberg | |
LITT and Pembrolizumab in Recurrent Brain Metastasis | NCT04187872 | Melanoma Non-small Cell ... Renal Cell Carc... Small-cell Lung... Head and Neck S... Classical Hodgk... Primary Mediast... Urothelial Carc... Microsatellite ... Gastric Cancer Esophageal Canc... Cervical Cancer Hepatocellular ... Merkel Cell Car... Brain Metastase... | LITT + Pembroli... | 18 Years - 100 Years | University of Florida | |
Accelerated Checkpoint Therapy for Any Steroid Dependent Patient With Brain Metastases | NCT04461418 | Brain Metastase... | Glucocorticoid ... | 18 Years - | AHS Cancer Control Alberta | |
A Study of Stereotactic Radiosurgery (SRS) for People With Lung Cancer That Has Spread to the Brain | NCT05419076 | Lung Cancer Lung Cancer Met... Brain Metastase... Brain Metastase... Small-cell Lung... Small Cell Lung... | Stereotactic Ra... Cerebrospinal f... | 18 Years - | Memorial Sloan Kettering Cancer Center | |
Stereotactic Radiosurgery vs Whole Brain Radiotherapy in Breast Cancer With Brain Oligometastasis | NCT05144867 | Breast Cancer Brain Metastase... Stereotactic Ra... Whole Brain Rad... | Stereotactic Ra... | 18 Years - 75 Years | PGIMER | |
Multi-disciplinary Care for Brain Metastases | NCT06280300 | Brain Metastase... | health services... | 18 Years - | University of Vermont Medical Center | |
Developing a New MRI Technique to Understand Changes in Brain Tumors After Treatment | NCT05559853 | Brain Metastase... Brain Metastase... Metastatic Brai... Metastatic Brai... | CEST-MRF | 18 Years - | Memorial Sloan Kettering Cancer Center | |
UCSD Image-Guided Cognitive-Sparing Radiosurgery for Brain Metastases | NCT04343157 | Brain Metastase... Neurocognitive ... Cancer | Cognitive Spari... | 18 Years - | University of California, San Diego | |
Stereotactic Radiosurgery vs Whole Brain Radiotherapy in Breast Cancer With Brain Oligometastasis | NCT05144867 | Breast Cancer Brain Metastase... Stereotactic Ra... Whole Brain Rad... | Stereotactic Ra... | 18 Years - 75 Years | PGIMER | |
Prospective Double Arm Randomized Trial: WBRT Alone and WBRT Plus Silibinin | NCT05793489 | Brain Metastase... | Silibinin | 18 Years - | Istituto Clinico Humanitas | |
Brain Imaging Biomarkers in Patients With Brain Metastasis | NCT04197297 | Brain Metastase... | CT and MRI Scan... | 18 Years - | University Health Network, Toronto | |
Comparaison Between MRI Alone or Combined With Positron Emission Tomography for Brain Metastasis Diagnosis | NCT05095766 | Brain Metastase... | 18 Years - | Centre de recherche du Centre hospitalier universitaire de Sherbrooke | ||
Combining Radiosurgery and Nivolumab in the Treatment of Brain Metastases | NCT02978404 | Clear-Cell Meta... Non Small Cell ... Brain Metastase... Small Cell Lung... Melanoma | Nivolumab Radiosurgery | 18 Years - | Centre hospitalier de l'Université de Montréal (CHUM) | |
Effect of Azeliragon Combined With Stereotactic Radiation Therapy in Patients With Brain Metastases | NCT05789589 | Cancer Metastasis Metastatic Canc... Brain Metastase... Brain Metastase... | Azeliragon Stereotactic ra... Corticosteroid | 18 Years - | Baptist Health South Florida | |
A Phase II Study of Pre-Op SRS Followed by Surgical Resection for Brain Metastases | NCT05341739 | Brain Metastase... | Pre-operative S... | 18 Years - | Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute) | |
Stereotactic Radiotherapy Management of Brain Metastases: the Value of a Longitudinal Multimodal Approach (POSTPONE) | NCT06029140 | Brain Metastase... | 18 Years - | University Hospital, Brest | ||
Exploring Compensation to Maintain Cognitive Function in Adults Newly Diagnosed With Brain Cancer | NCT04075370 | Primary Brain T... Brain Metastase... | Neuropsychologi... | 30 Years - 65 Years | Duke University | |
Hypofractionated Brain Radiationcavity | NCT03561896 | Brain Metastase... Cancer Brain | IGRT SRS | 18 Years - | Oncology Institute of Southern Switzerland | |
Stereotactic Radiotherapy Management of Brain Metastases: the Value of a Longitudinal Multimodal Approach (POSTPONE) | NCT06029140 | Brain Metastase... | 18 Years - | University Hospital, Brest |