Spots Global Cancer Trial Database for craniotomy
Every month we try and update this database with for craniotomy cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.
The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
| Study title | NCT ID | Conditions | Interventions | Eligibility | Organization | Link |
|---|---|---|---|---|---|---|
| Intravenous Acetaminophen for Craniotomy Patients | NCT01474304 | Craniotomy | Acetaminophen | 18 Years - | Swedish Medical Center | |
| Awake vs. Asleep Craniotomy for Non-eloquent Gliomas | NCT03621748 | Intracranial Gl... | Awake Anesthesi... Non-awake Anest... | 18 Years - | Mayo Clinic | |
| CNS and Extracranial Tumor Tissues, CSF, and Blood From Patients With Melanoma Brain Metastases | NCT02058953 | Melanoma Brain Metastase... | Craniotomy sche... Collection for ... | 18 Years - | University of Pittsburgh | |
| Bevacizumab With or Without Surgery for Adult Glioblastomas | NCT01413438 | Glioblastoma Brain Neoplasm | Craniotomy | 18 Years - | National Institutes of Health Clinical Center (CC) | |
| Intravenous Acetaminophen for Craniotomy Patients | NCT01474304 | Craniotomy | Acetaminophen | 18 Years - | Swedish Medical Center | |
| Ultrasound-guided Greater Occipital Nerve Block in Children Undergoing Posterior Fossa Craniotomy | NCT03762343 | Posterior Fossa... | ultrasound guid... control group C | 2 Years - 10 Years | Kasr El Aini Hospital | |
| Therapeutic Benefit of Preoperative Supplemental Vitamin D in Patients Undergoing Brain Tumor Surgery | NCT03248544 | Brain Neoplasms | vitamin D control | 18 Years - | Shahid Beheshti University | |
| Comparison of the Effect of Low and High Fraction of Inspired Oxygen on Postoperative Surgical Field Infection | NCT03454659 | Supratentorial ... | Craniotomy | 18 Years - 70 Years | Istanbul University | |
| Dexmedetomidine Infusion Effect on Hemodynamic Variables During Craniotomy | NCT04607525 | Hemodynamic Ins... Supratentorial ... | Dexmedetomidine normal saline | 18 Years - 65 Years | Ain Shams University | |
| Postoperative Risk Prediction Score After Elective Intracranial Neurosurgery Operation | NCT04585633 | Brain Tumor Post-Op Complic... Anesthesia | Quality of Reco... Glasgow Result ... Risk Factors | 18 Years - | Trakya University | |
| Postoperative Risk Prediction Score After Elective Intracranial Neurosurgery Operation | NCT04585633 | Brain Tumor Post-Op Complic... Anesthesia | Quality of Reco... Glasgow Result ... Risk Factors | 18 Years - | Trakya University | |
| Dose Escalation Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of QBS10072S | NCT04430842 | Astrocytoma Brain Cancer Brain Metastase... Bladder Cancer Breast Cancer Cervical Cancer Cholangiocarcin... Colorectal Canc... Esophagus Cance... Gastric Cancer Head and Neck C... Kidney Cancer Liver Cancer Lung Cancer Melanoma Ovarian Cancer Pancreatic Canc... Pleural Mesothe... Prostate Cancer Sarcoma Tongue Cancer Thymic Carcinom... Urinary Tract C... | QBS10072S | 18 Years - | Quadriga Biosciences, Inc. | |
| Scalp Block in Elective Craniotomy for Tumor Dissection Trial | NCT03776617 | Craniotomy | scalp block | 18 Years - | George Papanicolaou Hospital | |
| Effect of Continous Intravenous Lidocaine Infusion Intraoperative for Craniotomy Tumor Removal Surgery | NCT04773093 | Craniotomy Tumo... | Continous Intra... Placebo | 18 Years - 65 Years | Indonesia University | |
| Propofol-remifentanyl Versus Dexmedetomidine in Awake Craniotomy: Impact on Electroclinical Seizure Activity | NCT05103735 | Craniotomy Seizures Dexmedetomidine Propofol Remifentanil Cerebral Tumor Neurophysiology | Propofol | 18 Years - | Azienda Sanitaria-Universitaria Integrata di Udine | |
| The Relationship of Anesthesia Method With Serum Lactate Level in Craniotomies | NCT05145049 | Intracranial Ne... Hyperlactatemia Brain Tumor Hypoperfusion | 18 Years - | Ankara Diskapi Training and Research Hospital | ||
| Light Sedation or Intubated General Anesthesia in Patients With Brain Cancer Undergoing Craniotomy | NCT02193568 | Adult Brain Tum... | Arm I (light se... Arm II (intubat... Arm II (intubat... Arm II (intubat... Arm I (light se... Arm I (light se... | 19 Years - | Ohio State University Comprehensive Cancer Center | |
| Intraoperative Goal Directed Fluid Management in Supratentorial Brain Tumor Craniotomy | NCT03033706 | Brain Tumor Craniotomy | Pulse pressure ... Traditional flu... Brain tumor exc... | 18 Years - | Cairo University | |
| Allogenic Adipose-Derived Mesenchymal Stem Cells for the Treatment of Recurrent Glioblastoma in Patients Undergoing Craniotomy | NCT05789394 | Recurrent Gliob... | Allogeneic Adip... Biospecimen Col... Craniotomy Magnetic Resona... Ommaya Reservoi... | 18 Years - 65 Years | Mayo Clinic | |
| Intravenous Acetaminophen for Craniotomy Patients | NCT01474304 | Craniotomy | Acetaminophen | 18 Years - | Swedish Medical Center | |
| Dexmedetomidine and Intelligence Development in Pediatric Patients Undergoing Craniotomy | NCT02810899 | Brain Neoplasms | dexmedetomidine normal saline | 2 Years - 12 Years | Peking University First Hospital | |
| Effect of Different Positive End Expiratory Pressures on Regional Cerebral Oxygen Saturation | NCT05961917 | Regional Cerebr... | 5 cmH2O Positiv... 10 cmH2O Positi... | 18 Years - | Bozyaka Training and Research Hospital | |
| Sitting Versus Horizontal Position on Craniotomies | NCT03364283 | Craniotomy Brain Tumor | Surgical positi... | 18 Years - 75 Years | Ohio State University | |
| Effect of SNB on the QoR in Patients Undergoing Supratentorial Tumor Resection | NCT06157359 | Postoperative A... Quality of Reco... Supratentorial ... Craniotomy Scalp Nerve Blo... | scalp nerve blo... | 18 Years - 65 Years | Second Affiliated Hospital, School of Medicine, Zhejiang University | |
| Phase I Study of Orally Administered Aminolevulinic Acid for Resection of Malignant Astrocytomas | NCT01502605 | Astrocytoma Glioma | 5-Aminolevulini... | 18 Years - | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | |
| Investigational Imaging Technique During Brain Surgery | NCT05513859 | Astrocytoma Glioblastoma Oligodendroglio... | Craniotomy Quantitative Ob... | 18 Years - | Emory University | |
| Investigational Imaging Technique During Brain Surgery | NCT05513859 | Astrocytoma Glioblastoma Oligodendroglio... | Craniotomy Quantitative Ob... | 18 Years - | Emory University | |
| Intracavitary Carrier-embedded Cs131 Brachytherapy for Recurrent Brain Metastases: a Randomized Phase II Study | NCT04690348 | Recurrent Brain... | Craniotomy Cesium-131 brac... | 18 Years - | Memorial Sloan Kettering Cancer Center | |
| Dexmedetomidine Infusion Effect on Hemodynamic Variables During Craniotomy | NCT04607525 | Hemodynamic Ins... Supratentorial ... | Dexmedetomidine normal saline | 18 Years - 65 Years | Ain Shams University | |
| Comparison of the Effect of Low and High Fraction of Inspired Oxygen on Postoperative Surgical Field Infection | NCT03454659 | Supratentorial ... | Craniotomy | 18 Years - 70 Years | Istanbul University | |
| Comparison of Stroke Volume Variation-guided Normovolemic and Restrictive Fluid Management During Craniotomy: a Randomized Controlled Trial | NCT02113358 | Supratentorial ... Brain Tumor, Pr... Craniotomy | Intravenous col... | 20 Years - 70 Years | National Taiwan University Hospital | |
| Efficiency of Two Glucose Sampling Protocols for Maintenance of Euglycemia | NCT00993057 | Brain Neoplasms Intracranial An... | Insulin | 18 Years - | Northwestern University | |
| The Relationship of Anesthesia Method With Serum Lactate Level in Craniotomies | NCT05145049 | Intracranial Ne... Hyperlactatemia Brain Tumor Hypoperfusion | 18 Years - | Ankara Diskapi Training and Research Hospital | ||
| Intraoperative Goal Directed Fluid Management in Supratentorial Brain Tumor Craniotomy | NCT03033706 | Brain Tumor Craniotomy | Pulse pressure ... Traditional flu... Brain tumor exc... | 18 Years - | Cairo University | |
| Comparison of Stroke Volume Variation-guided Normovolemic and Restrictive Fluid Management During Craniotomy: a Randomized Controlled Trial | NCT02113358 | Supratentorial ... Brain Tumor, Pr... Craniotomy | Intravenous col... | 20 Years - 70 Years | National Taiwan University Hospital | |
| Intravenous Acetaminophen for Craniotomy Patients | NCT01474304 | Craniotomy | Acetaminophen | 18 Years - | Swedish Medical Center | |
| Ultrasound-guided Greater Occipital Nerve Block in Children Undergoing Posterior Fossa Craniotomy | NCT03762343 | Posterior Fossa... | ultrasound guid... control group C | 2 Years - 10 Years | Kasr El Aini Hospital | |
| Therapeutic Benefit of Preoperative Supplemental Vitamin D in Patients Undergoing Brain Tumor Surgery | NCT03248544 | Brain Neoplasms | vitamin D control | 18 Years - | Shahid Beheshti University | |
| The Effect of Different Ventilation Strategies on Cerebral Oxygenation Using Near Infrared Spectroscopy (NIRS) in Pediatrics Undergoing Posterior Fossa Tumor Surgery | NCT04232059 | Infratentorial ... Hyperventilatio... Craniotomy | cerebral oximet... | 1 Year - 6 Years | Kasr El Aini Hospital | |
| MiDura-Study (Neuro-Patch in Duraplasty) | NCT04189172 | Meningioma Tumor, Brain Chiari Malforma... Vascular Malfor... Hydrocephalus Tethered Cord Dural Fistula Craniotomy Spinal Surgery Duraplasty | 18 Years - | Aesculap AG | ||
| Effect of SNB on the QoR in Patients Undergoing Supratentorial Tumor Resection | NCT06157359 | Postoperative A... Quality of Reco... Supratentorial ... Craniotomy Scalp Nerve Blo... | scalp nerve blo... | 18 Years - 65 Years | Second Affiliated Hospital, School of Medicine, Zhejiang University | |
| Surgery Versus Radiosurgery to Treat Metastatic Brain Tumors | NCT00075166 | Brain Neoplasms Neoplasm Metast... | Stereotactic su... Craniotomy | - | National Institutes of Health Clinical Center (CC) | |
| Efficiency of Two Glucose Sampling Protocols for Maintenance of Euglycemia | NCT00993057 | Brain Neoplasms Intracranial An... | Insulin | 18 Years - | Northwestern University | |
| Propofol-remifentanyl Versus Dexmedetomidine in Awake Craniotomy: Impact on Electroclinical Seizure Activity | NCT05103735 | Craniotomy Seizures Dexmedetomidine Propofol Remifentanil Cerebral Tumor Neurophysiology | Propofol | 18 Years - | Azienda Sanitaria-Universitaria Integrata di Udine | |
| Scalp Nerve Block and Opioid Consumption in Brain Surgery | NCT02057367 | Brain Tumour | Scalp block wit... Scalp block wit... | 18 Years - 65 Years | Chiang Mai University | |
| Bevacizumab With or Without Surgery for Adult Glioblastomas | NCT01413438 | Glioblastoma Brain Neoplasm | Craniotomy | 18 Years - | National Institutes of Health Clinical Center (CC) | |
| The Effect of Different Ventilation Strategies on Cerebral Oxygenation Using Near Infrared Spectroscopy (NIRS) in Pediatrics Undergoing Posterior Fossa Tumor Surgery | NCT04232059 | Infratentorial ... Hyperventilatio... Craniotomy | cerebral oximet... | 1 Year - 6 Years | Kasr El Aini Hospital | |
| Scalp Nerve Block and Opioid Consumption in Brain Surgery | NCT02057367 | Brain Tumour | Scalp block wit... Scalp block wit... | 18 Years - 65 Years | Chiang Mai University | |
| Scalp Nerve Block and Opioid Consumption in Brain Surgery | NCT02057367 | Brain Tumour | Scalp block wit... Scalp block wit... | 18 Years - 65 Years | Chiang Mai University | |
| Effect of Different Positive End Expiratory Pressures on Regional Cerebral Oxygen Saturation | NCT05961917 | Regional Cerebr... | 5 cmH2O Positiv... 10 cmH2O Positi... | 18 Years - | Bozyaka Training and Research Hospital | |
| Dexmedetomidine and Intelligence Development in Pediatric Patients Undergoing Craniotomy | NCT02810899 | Brain Neoplasms | dexmedetomidine normal saline | 2 Years - 12 Years | Peking University First Hospital | |
| Sitting Versus Horizontal Position on Craniotomies | NCT03364283 | Craniotomy Brain Tumor | Surgical positi... | 18 Years - 75 Years | Ohio State University | |
| Evaluation of Lactate in Patients Undergoing Glial and Non Glial Mass Surgery With Craniotomy | NCT04584827 | Lactate Brain Tumor Post-Op Complic... | lactate level Glasgow Outcome... | 18 Years - | Trakya University |
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