Spots Global Cancer Trial Database for hyperthermic intraperitoneal chemotherapy
Every month we try and update this database with for hyperthermic intraperitoneal chemotherapy cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.
The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
| Study title | NCT ID | Conditions | Interventions | Eligibility | Organization | Link |
|---|---|---|---|---|---|---|
| Hyperthermic Intraperitoneal Chemotherapy With Cisplatin During Surgery or Cisplatin Before Surgery for the Treatment of Stage III or IV Ovarian, Fallopian Tube or Peritoneal Cancer | NCT05415709 | Fallopian Tube ... Fallopian Tube ... Fallopian Tube ... Ovarian Endomet... Ovarian Mucinou... Ovarian Serous ... Primary Periton... Primary Periton... Stage III Fallo... Stage III Ovari... Stage III Prima... Stage IIIA Fall... Stage IIIA Ovar... Stage IIIA Prim... Stage IIIA1 Fal... Stage IIIA1 Ova... Stage IIIA2 Fal... Stage IIIA2 Ova... Stage IIIB Fall... Stage IIIB Ovar... Stage IIIB Prim... Stage IIIC Fall... Stage IIIC Ovar... Stage IIIC Prim... Stage IV Fallop... Stage IV Ovaria... Stage IV Primar... Stage IVA Fallo... Stage IVA Ovari... Stage IVA Prima... Stage IVB Fallo... Stage IVB Ovari... Stage IVB Prima... | Carboplatin Cisplatin Cytoreductive S... Hyperthermic In... Paclitaxel Quality-of-Life... Questionnaire A... | 18 Years - | Ohio State University Comprehensive Cancer Center | |
| Risk of Acute Kidney Injury in Patients Undergoing Cytoreductive Surgery and Hyperthermic Intra-peritoneal Chemotherapy | NCT04941625 | Acute Kidney In... | serum cystatin ... serum beta-micr... urine | 20 Years - 75 Years | Chang Gung Memorial Hospital | |
| Efficacy of HIPEC in the Treatment of Locally Advanced Gastric Cancer After radIcal Gastrectomy With D2 | NCT02356276 | Gastric Cancer | D2 lymphadenect... Hyperthermic In... Systemic chemot... | 18 Years - 70 Years | Affiliated Cancer Hospital & Institute of Guangzhou Medical University | |
| A Randomized Prospective Trail of HIPEC in Recurrent Ovarian Cancer Patients With HRR Mutation | NCT04473339 | Ovarian Cancer Epithelial Ovar... Ovarian Cancer,... Hyperthermic In... Homologous Reco... | CRS+HIPEC CRS alone | 18 Years - 75 Years | Zhongnan Hospital | |
| Treatment Strategy for Stage IV Gastric Cancer With Positive Peritoneal Cytology as the Only Non-curable Factor | NCT02969122 | Stomach Neoplas... | standard gastre... hyperthermic in... Extensive intra... Preoperative ch... Postoperative c... | - | Peking University | |
| Cytoreductive Surgery Combined With HIPEC and Chemotherapy for Gastric Cancer With Peritoneal Metastasis | NCT03023436 | Stomach Neoplas... | Cytoreductive s... Hyperthermic In... Fluoropyrimidin... Cisplatin | 19 Years - 74 Years | Nanfang Hospital, Southern Medical University | |
| Administration of Hyperthermic Intraperitoneal Chemotherapy in the General Ward | NCT06277947 | Epithelial Ovar... | China Hyperther... | 18 Years - 70 Years | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | |
| Secondary Debulking Surgery +/- Hyperthermic Intraperitoneal Chemotherapy in Stage III Ovarian Cancer | NCT00426257 | Ovarian Cancer | Secondary debul... secondary debul... | 18 Years - 76 Years | The Netherlands Cancer Institute | |
| Effect of Sodium Thiosulfate on Nephrotoxicity of Cisplatin Intraperitoneal Heat-perfusion Chemotherapy | NCT05877911 | Epithelial Ovar... Acute Kidney In... | Sodium Sulfate Hydration Cisplatin | - | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | |
| Comparison of the Efficiency Between Intraoperative and Postoperative Hyperthermic Intraperitoneal Chemotherapy With Docetaxel Combine Oxaliplatin in Patients With Advanced Gastric Cancer | NCT04522011 | Stomach Neoplas... Hyperthermic In... | intraoperative ... | 18 Years - 65 Years | First Affiliated Hospital Xi'an Jiaotong University | |
| Study on Hyperthermic Intraperitoneal Chemotherapy After Resection of Pancreascarcinoma | NCT02863471 | Adenocarcinomas... | Gemcitabine | 18 Years - 100 Years | University Hospital Tuebingen | |
| Escalating Doses of Oxaliplatin and Hyperthermic Intraperitoneal Chemotherapy (HIPEC) in Children and Adolescents With Extensive Colon Carcinoma | NCT02062749 | Colorectal Canc... | Oxaliplatin | 9 Years - 21 Years | M.D. Anderson Cancer Center | |
| Effect of Sodium Thiosulfate on Nephrotoxicity of Cisplatin Intraperitoneal Heat-perfusion Chemotherapy | NCT05877911 | Epithelial Ovar... Acute Kidney In... | Sodium Sulfate Hydration Cisplatin | - | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | |
| Efficacy of HIPEC in the Treatment of Advanced-Stage Epithelial Ovarian Cancer After Cytoreductive Surgery | NCT03373058 | Epithelial Ovar... Fallopian Tube ... Primary Periton... | Hyperthermic In... cytoreductive s... adjuvant chemot... | 18 Years - 70 Years | Affiliated Cancer Hospital & Institute of Guangzhou Medical University | |
| Risk of Acute Kidney Injury in Patients Undergoing Cytoreductive Surgery and Hyperthermic Intra-peritoneal Chemotherapy | NCT04941625 | Acute Kidney In... | serum cystatin ... serum beta-micr... urine | 20 Years - 75 Years | Chang Gung Memorial Hospital | |
| Goal Directed Therapy (GDT) in Cytoreductive Surgery (CRS) and Hyperthermic Intra Peritoneal Chemotherapy (Hipec) | NCT01882920 | Primary Periton... Secondary Perit... | Goal Directed I... Conventional In... | 18 Years - | Regina Elena Cancer Institute | |
| Escalating Doses of Oxaliplatin and Hyperthermic Intraperitoneal Chemotherapy (HIPEC) in Children and Adolescents With Extensive Colon Carcinoma | NCT02062749 | Colorectal Canc... | Oxaliplatin | 9 Years - 21 Years | M.D. Anderson Cancer Center | |
| Treatment Strategy for Stage IV Gastric Cancer With Positive Peritoneal Cytology as the Only Non-curable Factor | NCT02969122 | Stomach Neoplas... | standard gastre... hyperthermic in... Extensive intra... Preoperative ch... Postoperative c... | - | Peking University | |
| HIPEC in the Treatment of Stage IIc-IV Epithelial Ovarian Cancer After CRS (HIPECOC) | NCT04280185 | Ovarian Cancer Hyperthermic In... | Hyperthermic In... | 18 Years - 70 Years | Second Affiliated Hospital, School of Medicine, Zhejiang University | |
| Efficacy of Neoadjuvant Hyperthermic Intraperitoneal Chemotherapy in Advanced High-grade Serous Ovarian Cancer (the NHIPEC Trial) | NCT05246020 | Hyperthermic In... Neoadjuvant Che... | HIPEC intravenous che... | 17 Years - 70 Years | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | |
| Study of Hyperthermic Intraperitoneal Chemoperfusion (HIPEC) in Patients With Gastric Adenocarcinoma and Carcinomatosis or Positive Cytology | NCT03330028 | Diseases of Oes... | Dexamethasone Diphenhydramine Famotidine Mitomycin C Cisplatin Paclitaxel | 18 Years - | M.D. Anderson Cancer Center | |
| Surgical Resection Combined With Intraperitoneal Hyperthermic Chemotherapy | NCT06247293 | Hyperthermic In... Hepatocellular ... Ruptured Liver | intraperitoneal... | 18 Years - 80 Years | Zhujiang Hospital | |
| Robotic Cytoreduction and Hyperthermic Intraperitoneal Chemotherapy for Treatment of Gastric Cancer With Limited Peritoneal Metastasis, ROBO-CHIP Study | NCT05753306 | Gastric Adenoca... Gastroesophagea... Metastatic Mali... | Biospecimen Col... Cisplatin Computed Tomogr... Docetaxel Gastrectomy Hyperthermic In... Magnetic Resona... Positron Emissi... Questionnaire A... | 18 Years - 80 Years | Mayo Clinic | |
| Heated Intra-peritoneal Chemotherapy With Doxorubicin and Cisplatin for Abdominal for Pelvic Tumors in Pediatric Patients | NCT04213794 | Malignant Abdom... Malignant Pelvi... Recurrent Colon... Recurrent Desmo... Recurrent Fallo... Recurrent Gastr... Recurrent Lipos... Recurrent Malig... Recurrent Ovari... Recurrent Prima... Recurrent Recta... Recurrent Rhabd... Recurrent Sarco... Refractory Colo... Refractory Desm... Refractory Fall... Refractory Gast... Refractory Lipo... Refractory Mali... Refractory Ovar... Refractory Prim... Refractory Rect... Refractory Rhab... Refractory Sarc... Resectable Lipo... Resectable Mali... Resectable Sarc... | Cisplatin Cytoreductive S... Doxorubicin Hyperthermic In... Sodium Thiosulf... Computed Tomogr... Magnetic Resona... Positron Emissi... Biospecimen Col... | 1 Year - 25 Years | Mayo Clinic | |
| Intraoperative Hyperthermic Intraperitoneal Chemotherapy With Ovarian Cancer | NCT01091636 | Epithelial Ovar... | Hyperthermic In... | - 75 Years | National Cancer Center, Korea | |
| Comparative Study of Lobaplatin and Paclitaxel in Advanced Gastric Cancer Patients With D2 Surgery Combined With Hyperthermic Intraperitoneal Chemotherapy | NCT04808466 | Gastric Cancer Chemotherapy Ef... Surgery Metastasis Survival | Paclitaxel Lobaplatin | 18 Years - 75 Years | Wuhan Union Hospital, China | |
| Chemotherapy With or Without Immunotherapy for Peritoneal Mesothelioma | NCT05001880 | Peritoneal Mali... | Atezolizumab Bevacizumab Biospecimen Col... Carboplatin Computed Tomogr... Cytoreductive S... Hyperthermic In... Pemetrexed Positron Emissi... | 18 Years - | National Cancer Institute (NCI) | |
| Cytoreductive Surgery Combined With HIPEC and Chemotherapy for Gastric Cancer With Peritoneal Metastasis | NCT03023436 | Stomach Neoplas... | Cytoreductive s... Hyperthermic In... Fluoropyrimidin... Cisplatin | 19 Years - 74 Years | Nanfang Hospital, Southern Medical University | |
| Hyperthermic Intraperitoneal Chemotherapy (HIPEC) in Ovarian Cancer (CHIPPI) | NCT03842982 | Ovary Neoplasms Ovarian Cancer Ovarian Carcino... | HIPEC | 18 Years - 76 Years | Centre Oscar Lambret | |
| Heated Mitomycin and Cisplatin During Surgery in Treating Patients With Stomach or Gastroesophageal Cancer | NCT02891447 | Gastric Adenoca... Gastroesophagea... Peritoneal Carc... | Cisplatin Hyperthermic In... Mitomycin | 18 Years - | M.D. Anderson Cancer Center | |
| Robotic Cytoreduction and Hyperthermic Intraperitoneal Chemotherapy for Treatment of Gastric Cancer With Limited Peritoneal Metastasis, ROBO-CHIP Study | NCT05753306 | Gastric Adenoca... Gastroesophagea... Metastatic Mali... | Biospecimen Col... Cisplatin Computed Tomogr... Docetaxel Gastrectomy Hyperthermic In... Magnetic Resona... Positron Emissi... Questionnaire A... | 18 Years - 80 Years | Mayo Clinic | |
| Chemotherapy With or Without Immunotherapy for Peritoneal Mesothelioma | NCT05001880 | Peritoneal Mali... | Atezolizumab Bevacizumab Biospecimen Col... Carboplatin Computed Tomogr... Cytoreductive S... Hyperthermic In... Pemetrexed Positron Emissi... | 18 Years - | National Cancer Institute (NCI) | |
| Hyperthermic Intraperitoneal Chemotherapy for the Treatment of Pancreatic Cancer and Peritoneal Metastasis | NCT04858009 | Metastatic Panc... Stage IV Pancre... Metastatic Mali... | Cisplatin Hyperthermic In... Nab-paclitaxel Computed Tomogr... Magnetic Resona... Positron Emissi... | 18 Years - 80 Years | Mayo Clinic | |
| Technical Feasibility of Modified Early Post-Operative Intraperitoneal Chemotherapy (mEPIC) | NCT05913674 | Peritoneal Carc... Appendiceal Neo... Colorectal Canc... | Modified early ... | 18 Years - | Ciusss de L'Est de l'Île de Montréal | |
| Pathophysiology of Inflammation After Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy | NCT02741167 | Peritoneal Canc... | CRS and HIPEC | 18 Years - | University of Zurich | |
| ICARuS Post-operative Intraperitoneal Chemotherapy (EPIC) and Hyperthermic Intraperitoneal Chemotherapy (HIPEC) After Optimal Cytoreductive Surgery (CRS) for Neoplasms of the Appendix, Colon or Rectum With Isolated Peritoneal Metastasis | NCT01815359 | Appendix Cancer Colorectal Canc... | Cytoreductive S... HIPEC with Mito... EPIC with FUDR ... | 18 Years - | Memorial Sloan Kettering Cancer Center | |
| A Randomized Prospective Trail of HIPEC in Recurrent Ovarian Cancer Patients With HRR Mutation | NCT04473339 | Ovarian Cancer Epithelial Ovar... Ovarian Cancer,... Hyperthermic In... Homologous Reco... | CRS+HIPEC CRS alone | 18 Years - 75 Years | Zhongnan Hospital | |
| Role of Magnetic Resonance Enterography for Predicting Peritoneal Cancer Index | NCT05063019 | Hyperthermic In... Cytoreductive S... Peritoneal Carc... | MRI | 20 Years - 80 Years | Chang Gung Memorial Hospital | |
| Study of Hyperthermic Intraperitoneal Chemoperfusion (HIPEC) in Patients With Gastric Adenocarcinoma and Carcinomatosis or Positive Cytology | NCT03330028 | Diseases of Oes... | Dexamethasone Diphenhydramine Famotidine Mitomycin C Cisplatin Paclitaxel | 18 Years - | M.D. Anderson Cancer Center | |
| Pathophysiology of Inflammation After Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy | NCT02741167 | Peritoneal Canc... | CRS and HIPEC | 18 Years - | University of Zurich | |
| Cytoreductive Surgery (CRS) With/Without HIPEC in Gastric Cancer With Peritoneal Carcinomatosis | NCT02158988 | Malignant Neopl... Secondary Malig... Secondary Malig... | HIPEC | 18 Years - 75 Years | Charite University, Berlin, Germany | |
| Cytoreductive Surgery(CRS) Plus Hyperthermic Intraperitoneal Chemotherapy(HIPEC) With Lobaplatin in Advanced and Recurrent Epithelial Ovarian Cancer | NCT03371693 | Ovarian Cancer Ovary Neoplasm Ovarian Neoplas... Epithelial Ovar... Ovarian Cancer,... Hyperthermic In... | HIPEC CRS IVCT | 18 Years - 75 Years | Zhongnan Hospital | |
| Peritoneal Surface Malignancies - Characterization, Models and Treatment Strategies | NCT02073500 | Pseudomyxoma Pe... Colorectal Carc... Ovarian Carcino... Mesothelioma | Observational s... | 18 Years - | Oslo University Hospital | |
| Adjuvant Hyperthermic Intraperitoneal Chemotherapy (HIPEC) Versus no HIPEC in Locally Advanced Colorectal Cancer (APEC Study) | NCT02965248 | Locally Advance... | Standard adjuva... Hyperthermic in... Hyperthermic in... | 18 Years - 75 Years | Fudan University | |
| Preoperative Systemic Therapy for Colorectal Cancer Peritoneal Metastases | NCT05353582 | Colorectal Neop... Colorectal Canc... Colorectal Canc... Peritoneal Meta... Peritoneal Canc... Peritoneal Neop... Chemotherapy Ef... Cytoreductive S... Hyperthermic In... | Preoperative sy... CRS+HIPEC Postoperative c... Postoperative c... | 18 Years - 75 Years | Sun Yat-sen University | |
| Heated Intra-peritoneal Chemotherapy With Doxorubicin and Cisplatin for Abdominal for Pelvic Tumors in Pediatric Patients | NCT04213794 | Malignant Abdom... Malignant Pelvi... Recurrent Colon... Recurrent Desmo... Recurrent Fallo... Recurrent Gastr... Recurrent Lipos... Recurrent Malig... Recurrent Ovari... Recurrent Prima... Recurrent Recta... Recurrent Rhabd... Recurrent Sarco... Refractory Colo... Refractory Desm... Refractory Fall... Refractory Gast... Refractory Lipo... Refractory Mali... Refractory Ovar... Refractory Prim... Refractory Rect... Refractory Rhab... Refractory Sarc... Resectable Lipo... Resectable Mali... Resectable Sarc... | Cisplatin Cytoreductive S... Doxorubicin Hyperthermic In... Sodium Thiosulf... Computed Tomogr... Magnetic Resona... Positron Emissi... Biospecimen Col... | 1 Year - 25 Years | Mayo Clinic | |
| HIPEC-AS in Patients With Peritoneal Metastasis of the Stomach or Esophagogastric Junction | NCT05095467 | Stomach Neoplas... Peritoneal Meta... | HIPEC Paclitaxel-albu... Tegafur-gimerac... Surgery+HIPEC | 18 Years - 75 Years | Shanghai Zhongshan Hospital | |
| A Phase I Dose-finding Trial of Hyperthermic Intraperitoneal Paclitaxel Combined With Cisplatin | NCT05620654 | Ovarian Cancer Hyperthermic In... Paclitaxel | Hyperthermic In... | 18 Years - 75 Years | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | |
| A Randomized Prospective Trail of HIPEC in Recurrent Ovarian Cancer Patients With HRR Mutation | NCT04473339 | Ovarian Cancer Epithelial Ovar... Ovarian Cancer,... Hyperthermic In... Homologous Reco... | CRS+HIPEC CRS alone | 18 Years - 75 Years | Zhongnan Hospital | |
| Efficacy of Intraoperative Use of 20% Albumin Combined With Ringer Lactate Versus Ringer Lactate During Cytoreductive Surgery With Hyperthermic Intraperitoneal Chemotherapy | NCT06351475 | Peritoneal Neop... Hyperthermic In... Intraoperative ... Fluid Therapy Postoperative C... | Intra-operative... Control | 18 Years - 80 Years | Assistance Publique - Hôpitaux de Paris | |
| Efficacy of HIPEC as NACT and Postoperative Chemotherapy in the Treatment of Advanced-Stage Epithelial Ovarian Cancer | NCT03180177 | Epithelial Ovar... Fallopian Tube ... Primary Periton... | Hyperthermic In... Interval debulk... neoadjuvant che... adjuvant chemot... | 18 Years - 70 Years | Affiliated Cancer Hospital & Institute of Guangzhou Medical University | |
| Intraoperative Hyperthermic Intraperitoneal Chemotherapy With Ovarian Cancer | NCT01091636 | Epithelial Ovar... | Hyperthermic In... | - 75 Years | National Cancer Center, Korea | |
| Circulating Tumour Cells in Patients With Peritoneal Metastases | NCT04083547 | Circulating Tum... Peritoneal Meta... Hyperthermic In... | iCellate | 18 Years - 80 Years | Uppsala University | |
| Prophylactic Surgery Plus HIPEC With CO2 in Patients Affected by Gastric Carcinoma.GOETH Study | NCT03917173 | Stomach Neoplas... | Surgery plus HI... Standard surger... | 18 Years - 75 Years | Mario Negri Institute for Pharmacological Research | |
| An Audit of Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy | NCT02754115 | Colorectal Canc... Ovarian Cancer Peritoneal Dise... | Hyperthermic in... | 18 Years - 70 Years | Tata Memorial Centre | |
| Surgical Resection Combined With Intraperitoneal Hyperthermic Chemotherapy | NCT06247293 | Hyperthermic In... Hepatocellular ... Ruptured Liver | intraperitoneal... | 18 Years - 80 Years | Zhujiang Hospital | |
| Efficacy of HIPEC in the Treatment of Advanced-Stage Epithelial Ovarian Cancer After Cytoreductive Surgery | NCT03373058 | Epithelial Ovar... Fallopian Tube ... Primary Periton... | Hyperthermic In... cytoreductive s... adjuvant chemot... | 18 Years - 70 Years | Affiliated Cancer Hospital & Institute of Guangzhou Medical University | |
| An Audit of Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy | NCT02754115 | Colorectal Canc... Ovarian Cancer Peritoneal Dise... | Hyperthermic in... | 18 Years - 70 Years | Tata Memorial Centre | |
| Pathophysiology of Inflammation After Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy | NCT02741167 | Peritoneal Canc... | CRS and HIPEC | 18 Years - | University of Zurich | |
| Psychological distREsS hipEc oR pelVic Exenteration | NCT04956107 | Colo-rectal Can... | 18 Years - | University of Aarhus | ||
| Efficacy of HIPEC in Patients With Colorectal Cancer at High Risk of Peritoneal Carcinomatosis | NCT04370925 | Colorectal Canc... | Radical colecto... HIPEC Systemic chemot... | 18 Years - 70 Years | Affiliated Cancer Hospital & Institute of Guangzhou Medical University | |
| Gastrectomy + Cytoreductive Surgery + HIPEC for Gastric Cancer With Peritoneal Dissemination. | NCT03348150 | Stomach Neoplas... Peritoneal Carc... | Cytoreductive s... Hyperthermic In... | 18 Years - | The Netherlands Cancer Institute | |
| Efficacy of Intraoperative Use of 20% Albumin Combined With Ringer Lactate Versus Ringer Lactate During Cytoreductive Surgery With Hyperthermic Intraperitoneal Chemotherapy | NCT06351475 | Peritoneal Neop... Hyperthermic In... Intraoperative ... Fluid Therapy Postoperative C... | Intra-operative... Control | 18 Years - 80 Years | Assistance Publique - Hôpitaux de Paris | |
| Gastrectomy + Cytoreductive Surgery + HIPEC for Gastric Cancer With Peritoneal Dissemination. | NCT03348150 | Stomach Neoplas... Peritoneal Carc... | Cytoreductive s... Hyperthermic In... | 18 Years - | The Netherlands Cancer Institute |
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