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Spots Global Cancer Trial Database for cancer vaccine

Every month we try and update this database with for cancer vaccine cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.

Study titleNCT IDConditionsInterventionsEligibilityOrganizationLink
A Clinical Trial Investigating the Safety, Tolerability, and Therapeutic Effects of BNT113 in Combination With Pembrolizumab Versus Pembrolizumab Alone for Patients With a Form of Head and Neck Cancer Positive for Human Papilloma Virus 16 and Expressing the Protein PD-L1NCT04534205
Unresectable He...
Metastatic Head...
Recurrent Head ...
BNT113
Pembrolizumab
18 Years - BioNTech SE
Combination of UCPVax Vaccine and Atezolizumab for the Treatment of Human Papillomavirus Positive Cancers (VolATIL)NCT03946358
Squamous Cell C...
Anal Canal Canc...
Cervical Cancer
Blood sample co...
Tumor biopsies
CT scan
Atezolizumab
UCPVax
18 Years - 75 YearsCentre Hospitalier Universitaire de Besancon
Adjuvant Therapeutic Cancer Vaccine (AST-201, pUMVC3-hIGFBP-2) in Patients With Advanced Ovarian CancerNCT05794659
Advanced Ovaria...
AST-201
Paclitaxel
Carboplatin
Placebo
rhuGM-CSF(Granu...
18 Years - Aston Sci. Inc.
Adjuvant GVAX Vaccine Therapy in Patients With Pancreatic CancerNCT00389610
Pancreatic Canc...
GVAX pancreas v...
18 Years - Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Tumor Cell Vaccines and ISCOMATRIX With Chemotherapy After Tumor RemovalNCT01341496
Sarcoma
Melanoma
Epithelial Mali...
Pleural Maligna...
Epigenetically ...
Cyclophosphamid...
Celecoxib
18 Years - 99 YearsNational Institutes of Health Clinical Center (CC)
Combination of UCPVax Vaccine and Atezolizumab for the Treatment of Human Papillomavirus Positive Cancers (VolATIL)NCT03946358
Squamous Cell C...
Anal Canal Canc...
Cervical Cancer
Blood sample co...
Tumor biopsies
CT scan
Atezolizumab
UCPVax
18 Years - 75 YearsCentre Hospitalier Universitaire de Besancon
Dendritic Cell Cancer Vaccine for High-grade GliomaNCT01213407
Glioblastoma Mu...
Trivax, Temozol...
Temozolomide, S...
3 Years - 70 YearsActivartis Biotech
STRIDE - STimulating Immune Response In aDvanced brEast CancerNCT00925548
Breast Cancer
Tecemotide (L-B...
Placebo of tece...
cyclophosphamid...
sodium chloride...
18 Years - EMD Serono
A Study of the Efficacy and Safety of RO7198457 in Combination With Atezolizumab Versus Atezolizumab Alone Following Adjuvant Platinum-Doublet Chemotherapy in Participants Who Are ctDNA Positive After Surgical Resection of Stage II-III Non-Small Cell Lung CancerNCT04267237
Non-small Cell ...
Atezolizumab
RO7198457
18 Years - Hoffmann-La Roche
Study of NY-ESO-1 ISCOMATRIX® in Patients With High-risk, Resected MelanomaNCT00199901
Melanoma
NY-ESO-1 ISCOMA...
ISCOMATRIX® adj...
18 Years - Ludwig Institute for Cancer Research
Safety Study of a Dendritic Cell-based Cancer Vaccine in MelanomaNCT01863108
Melanoma
Tumor Vaccines
Effects of Immu...
GeniusVac-Mel4
18 Years - University Hospital, Grenoble
Pembrolizumab, Lenvatinib and IL-15 Superagonist N-803 in Combination With HER2 Targeting Autologous Dendritic Cell (AdHER2DC) Vaccine in Participants With Advanced or Metastatic Endometrial CancerNCT06253494
Endometrial Can...
Cancer of Endom...
Carcinoma of En...
Endometrial Car...
AdHER2DC vaccin...
Pembrolizumab
N-803
Lenvatinib
PATHWAY HER2 (4...
18 Years - 120 YearsNational Institutes of Health Clinical Center (CC)
Phase II Cancer Vaccine Trial for Patients With Follicular LymphomaNCT01926639
Follicular Lymp...
Radiotherapy, r...
18 Years - Oslo University Hospital
A Study of the Efficacy and Safety of RO7198457 in Combination With Atezolizumab Versus Atezolizumab Alone Following Adjuvant Platinum-Doublet Chemotherapy in Participants Who Are ctDNA Positive After Surgical Resection of Stage II-III Non-Small Cell Lung CancerNCT04267237
Non-small Cell ...
Atezolizumab
RO7198457
18 Years - Hoffmann-La Roche
A Pilot Study of NY-ESO-1b Peptide Plus CpG 7909 and Montanide® ISA-51 in Patients With Cancer.NCT00199836
Cancer
Neoplasm
NY-ESO-1b pepti...
18 Years - Ludwig Institute for Cancer Research
PROvenge Treatment and Early Cancer TreatmentNCT00779402
Prostate Cancer
Control
Sipuleucel-T
18 Years - 80 YearsDendreon
Neoantigen Derived DCs as Cancer TreatmentNCT05767684
Refractory Tumo...
Solid Tumor
Dendritic Cell ...
Lenvatinib
Nivolumab
20 Years - National Health Research Institutes, Taiwan
Tumor Cell Vaccines and ISCOMATRIX With Chemotherapy After Tumor RemovalNCT01341496
Sarcoma
Melanoma
Epithelial Mali...
Pleural Maligna...
Epigenetically ...
Cyclophosphamid...
Celecoxib
18 Years - 99 YearsNational Institutes of Health Clinical Center (CC)
A Cancer Vaccine (CG8123) Given With and Without Cyclophosphamide for Advanced Stage Non-Small Cell Lung Cancer (NSCLC)NCT00089726
Lung Cancer
Carcinoma, Non-...
CG8123
Cyclophosphamid...
18 Years - Cell Genesys
Comparison of the Human Papillomavirus (HPV) Type 16 E7-Specific Immune Response Between a Normal Population and Patients With Cervical LesionsNCT00154583
Cervical Cancer
18 Years - 80 YearsNational Taiwan University Hospital
Study To Test the Safety and Efficacy of TVI-Brain-1 As A Treatment for Recurrent Grade IV GliomaNCT01290692
Grade IV Glioma
Grade IV Astroc...
Glioblastoma Mu...
TVI-Brain-1
18 Years - TVAX Biomedical
Study of NY-ESO-1 ISCOMATRIX® in Patients With High-risk, Resected MelanomaNCT00199901
Melanoma
NY-ESO-1 ISCOMA...
ISCOMATRIX® adj...
18 Years - Ludwig Institute for Cancer Research
AlloStim® In-Situ Vaccine in Pre-Treated Metastatic Colorectal CancerNCT01741038
Metastatic Colo...
AlloStim®
cryoablation
Physician's Cho...
18 Years - Immunovative Therapies, Ltd.
Autologous TLPO Vaccine BasketNCT06175221
Tumor, Solid
Tumor Metastasi...
Cancer
Tumor
Tumor lysate, p...
18 Years - Elios Therapeutics, LLC
Vaccine Therapy for Treating Patients With Previously Untreated Chronic Lymphocytic Leukemia (CLL)NCT01976520
Chronic Lymphoc...
Oncoquest-CLL v...
18 Years - XEME Biopharma Inc.
IMA910 Plus GM-CSF With Low-dose Cyclophosphamide Pre-treatment in Advanced Colorectal Carcinoma Patients Following a Successful 12 Week First-line Treatment With Oxaliplatin-based Chemotherapy (IMA910-101)NCT00785122
Colorectal Carc...
Endoxana, Leuki...
Endoxana, Leuki...
18 Years - Immatics Biotechnologies GmbH
rHSC-DIPGVax Plus Checkpoint Blockade for the Treatment of Newly Diagnosed DIPG and DMGNCT04943848
Diffuse Intrins...
Diffuse Midline...
rHSC-DIPGVax
Balstilimab
Zalifrelimab
12 Months - 18 YearsAnn & Robert H Lurie Children's Hospital of Chicago
DN24-02 as Adjuvant Therapy in Subjects With High Risk HER2+ Urothelial CarcinomaNCT01353222
Urothelial Carc...
DN24-02
Standard of Car...
18 Years - Dendreon
Adjuvant Tumor Lysate Vaccine and Iscomatrix With or Without Metronomic Oral Cyclophosphamide and Celecoxib in Patients With Malignancies Involving Lungs, Esophagus, Pleura, or MediastinumNCT02054104
Thoracic Sarcom...
Thorasic Cancer...
Cancers of Non-...
Sarcoma
Melanoma
H1299 cell lysa...
Cyclophosphamid...
Celecoxib
Iscomatrix adju...
18 Years - National Institutes of Health Clinical Center (CC)
Clinical Study of Personalized mRNA Vaccine Encoding Neoantigen in Patients With Advanced Esophageal Cancer and Non-small Cell Lung CancerNCT03908671
Esophageal Canc...
Non Small Cell ...
Personalized mR...
18 Years - 75 YearsStemirna Therapeutics
Phase II Feasibility Study of Dendritic Cell Vaccination for Newly Diagnosed Glioblastoma MultiformeNCT00323115
Glioblastoma Mu...
Autologous Dend...
Temozolomide
Radiotherapy
Dendritic Cell ...
18 Years - Dartmouth-Hitchcock Medical Center
Liver Cancer Immunotherapy: Placebo-controlled Clinical Trial of Hepcortespenlisimut-LNCT02232490
Hepatocellular ...
HCC
Liver Cancer
hepcortespenlis...
Placebo
18 Years - Immunitor LLC
Tumor Cell Vaccine for Patients Undergoing Surgery for Sarcomas, Melanomas, Germ Cell Tumors, or Malignancies That Have Metastasized to the Lungs, Pleura, or MediastinumNCT01313429
Sarcoma
Melanoma
Epithelial Mali...
Pleural Maligna...
Cyclophosphamid...
Allogenic tumor...
Celecoxib
18 Years - 99 YearsNational Institutes of Health Clinical Center (CC)
Study of a DNA Immunotherapy to Treat MelanomaNCT01138410
Malignant Melan...
SCIB1
18 Years - Scancell Ltd
Phase 1 Study of NY-ESO-1 Overlapping Peptides in Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal CancerNCT00616941
Epithelial Ovar...
Fallopian Tube ...
Primary Periton...
NY-ESO-1 OLP4
NY-ESO-1 OLP4 +...
NY-ESO-1 OLP4 +...
18 Years - Ludwig Institute for Cancer Research
Vaccination With PD-L1 Peptide Against Multiple MyelomaNCT03042793
Multiple Myelom...
PD-L1 peptide v...
18 Years - Herlev Hospital
The Role of B7-H4 in Tumor VaccineNCT06156150
Glioma
tumor vaccine
18 Years - 80 YearsHuashan Hospital
QUILT-3.013: Study of Ad5 [E1-, E2b-]-HER2/Neu Vaccine (ETBX-021) in Subjects With Unresectable Locally Advanced or Metastatic HER2-Expressing Breast CancerNCT02751528
Cancer
ETBX-021
18 Years - NantBioScience, Inc.
VXM01 Phase I Dose Escalation Study in Patients With Locally Advanced, Inoperable and Stage IV Pancreatic CancerNCT01486329
Stage IV Pancre...
VXM01
Placebo
18 Years - Vaximm GmbH
Safety and Activity of PolyPEPI1018 Plus Atezolizumab in Colorectal Cancer.NCT05243862
Colorectal Canc...
PolyPEPI1018
Atezolizumab
18 Years - Treos Bio Limited
VXM01 Phase I Dose Escalation Study in Patients With Locally Advanced, Inoperable and Stage IV Pancreatic CancerNCT01486329
Stage IV Pancre...
VXM01
Placebo
18 Years - Vaximm GmbH
A Study of ZYC300 Administered With Cyclophosphamide Pre-DosingNCT00381173
Breast Cancer
Ovarian Cancer
Prostate Cancer
Colon Cancer
Renal Cancer
Cyclophosphamid...
18 Years - Eisai Inc.
Study of NY-ESO-1 ISCOMATRIX® in Patients With Measurable Stage III or IV MelanomaNCT00518206
Melanoma
NY-ESO-1 ISCOMA...
Cyclophosphamid...
18 Years - Ludwig Institute for Cancer Research
Phase II Cancer Vaccine Trial for Patients With Follicular LymphomaNCT01926639
Follicular Lymp...
Radiotherapy, r...
18 Years - Oslo University Hospital
Phase I Study of CDX-1307, hCG-B Vaccine, for Patients With Incurable, Locally Advanced or Metastatic Breast, Colorectal, Pancreatic, Bladder or Ovarian CancerNCT00648102
Breast Cancer
Colorectal Canc...
Pancreatic Canc...
Bladder Cancer
Ovarian Cancer
CDX-1307
18 Years - Celldex Therapeutics
Immunotherapy With TG4010 in Patients With Advanced Non-Small Cell Lung CancerNCT00415818
Carcinoma, Non-...
MVA-MUC1-IL2
1st line Chemot...
18 Years - Transgene
Prototype DAA/TAA Vaccine Targeting MUC1 for Immune Interception and Prevention in Ductal Carcinoma In SituNCT06218303
Ductal Carcinom...
MUC1 Peptide Va...
Hiltonol®
Aromatase Inhib...
18 Years - University of Pittsburgh
Clinical Trial Evaluating the Safety, Tolerability and Preliminary Efficacy of BNT116 Alone and in Combinations in Patients With Advanced Non-small Cell Lung CancerNCT05142189
Non-Small Cell ...
BNT116
Cemiplimab
Docetaxel
Carboplatin
Paclitaxel
18 Years - BioNTech SE
QUILT-3.013: Study of Ad5 [E1-, E2b-]-HER2/Neu Vaccine (ETBX-021) in Subjects With Unresectable Locally Advanced or Metastatic HER2-Expressing Breast CancerNCT02751528
Cancer
ETBX-021
18 Years - NantBioScience, Inc.
Sipuleucel-T Manufacturing Demonstration StudyNCT01477749
Cancer of Prost...
Cancer of the P...
Neoplasms, Pros...
Neoplasms, Pros...
Prostate Cancer
Prostate Neopla...
Prostatic Cance...
sipuleucel-T
18 Years - Dendreon
Safety and Efficacy of Combination Listeria/GVAX Pancreas Vaccine in the Pancreatic Cancer SettingNCT02004262
2nd-line, 3rd-l...
GVAX Pancreas V...
CRS-207
Chemotherapy
cyclophosphamid...
18 Years - Aduro Biotech, Inc.
Immunotherapy for Third Line Metastatic Colorectal CancerNCT04444622
Metastatic Colo...
AlloStim
18 Years - Immunovative Therapies, Ltd.
Dendritic Cell Based Therapy for Breast Cancer PatientsNCT00935558
Breast Cancer
DC vaccine
aromatase inhib...
18 Years - Herlev Hospital
Phase II Trial of Allovectin-7® for Head and Neck CancerNCT00050388
Head and Neck C...
Squamous Cell C...
Head and Neck N...
Carcinoma of th...
Allovectin-7®
18 Years - Vical
A Phase II Trial of CG 8020 and CG 2505 in Patients With Nonresectable or Metastatic Pancreatic CancerNCT00245362
Metastatic Panc...
Nonresectable P...
CG 8020 and CG ...
18 Years - Cell Genesys
A Trial to Learn How the Cancer Vaccine BNT116 in Combination With Cemiplimab Works and How Safe the Combination is in Adults With Advanced Non-small Cell Lung Cancer (EMPOWERVAX Lung 1)NCT05557591
Advanced Non-Sm...
BNT116
Cemiplimab
18 Years - Regeneron Pharmaceuticals
Vaccination With PD-L1 Peptide Against Multiple MyelomaNCT03042793
Multiple Myelom...
PD-L1 peptide v...
18 Years - Herlev Hospital
Autologous Dendritic Cells, Metronomic Cyclophosphamide and Checkpoint Blockade in Children With Relapsed HGGNCT03879512
Childhood Gliob...
depletion of re...
reoperation
cancer vaccine
checkpoint bloc...
3 Years - 21 YearsWuerzburg University Hospital
A Phase 3, Randomized, Double-blind, Placebo-controlled Study For Subjects With Locally-advanced Unresectable or Metastatic Synovial Sarcoma (V943-003, IMDZ-04-1702)NCT03520959
Synovial Sarcom...
Cancer
Soft Tissue Sar...
Sarcoma
Metastatic Sarc...
LV305
G305
LV305-matching ...
G305-matching p...
12 Years - Immune Design, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
AlloStim® Immunotherapy Dosing Alone or in Combination With Cryoablation in Metastatic Colorectal CancerNCT02380443
Colorectal Canc...
AlloStim
Cryoablation
18 Years - 80 YearsImmunovative Therapies, Ltd.
Pilot Study of Allogeneic Tumor Cell Vaccine With Metronomic Oral Cyclophosphamide and Celecoxib in Patients Undergoing Resection of Lung and Esophageal Cancers, Thymic Neoplasms, and Malignant Pleural MesotheliomasNCT01143545
Lung Cancer
Esophageal Canc...
Malignant Pleur...
Sarcoma
Thymic Carcinom...
Allogeneic Tumo...
Celecoxib
cyclophosphamid...
18 Years - National Institutes of Health Clinical Center (CC)
Clinical Trial Evaluating the Safety, Tolerability and Preliminary Efficacy of BNT116 Alone and in Combinations in Patients With Advanced Non-small Cell Lung CancerNCT05142189
Non-Small Cell ...
BNT116
Cemiplimab
Docetaxel
Carboplatin
Paclitaxel
18 Years - BioNTech SE
Sequencing of Sipuleucel-T and ADT in Men With Non-metastatic Prostate CancerNCT01431391
Prostatic Neopl...
Prostate Cancer
Prostatic Adeno...
sipuleucel-T
leuprolide acet...
18 Years - Dendreon
IMA910 Plus GM-CSF With Low-dose Cyclophosphamide Pre-treatment in Advanced Colorectal Carcinoma Patients Following a Successful 12 Week First-line Treatment With Oxaliplatin-based Chemotherapy (IMA910-101)NCT00785122
Colorectal Carc...
Endoxana, Leuki...
Endoxana, Leuki...
18 Years - Immatics Biotechnologies GmbH
Phase II Study of S-488410 to Treat Non-small Cell Lung CancerNCT01592617
Carcinoma, Non-...
S-488410
20 Years - 79 YearsShiga University
Neoantigen Dendritic Cell Vaccine and Nivolumab in HCC and Liver Metastases From CRCNCT04912765
Hepatocellular ...
Hepatocellular ...
Colorectal Canc...
Colorectal Carc...
Liver Metastase...
Neoantigen Dend...
Nivolumab
21 Years - National Cancer Centre, Singapore
DN24-02 as Adjuvant Therapy in Subjects With High Risk HER2+ Urothelial CarcinomaNCT01353222
Urothelial Carc...
DN24-02
Standard of Car...
18 Years - Dendreon
AlloStim® Immunotherapy Dosing Alone or in Combination With Cryoablation in Metastatic Colorectal CancerNCT02380443
Colorectal Canc...
AlloStim
Cryoablation
18 Years - 80 YearsImmunovative Therapies, Ltd.
Study of NY-ESO-1 ISCOMATRIX® in Patients With High-risk, Resected MelanomaNCT00199901
Melanoma
NY-ESO-1 ISCOMA...
ISCOMATRIX® adj...
18 Years - Ludwig Institute for Cancer Research
Combination Study of SV-BR-1-GM With RetifanlimabNCT03328026
Breast Cancer
Breast Neoplasm
Metastatic Brea...
Breast Cancer M...
SV-BR-1-GM
Low dose cyclop...
Interferon Inoc...
retifanlimab
18 Years - BriaCell Therapeutics Corporation
DC Vaccine in Colorectal CancerNCT03730948
Colorectal Canc...
DC vaccine
18 Years - University of Pennsylvania
Safety and Efficacy of Listeria in Combination With Chemotherapy as Front-line Treatment for Malignant Pleural MesotheliomaNCT01675765
Malignant Pleur...
Immunotherapy p...
Immunotherapy w...
18 Years - Aduro Biotech, Inc.
Adjuvant Tumor Lysate Vaccine and Iscomatrix With or Without Metronomic Oral Cyclophosphamide and Celecoxib in Patients With Malignancies Involving Lungs, Esophagus, Pleura, or MediastinumNCT02054104
Thoracic Sarcom...
Thorasic Cancer...
Cancers of Non-...
Sarcoma
Melanoma
H1299 cell lysa...
Cyclophosphamid...
Celecoxib
Iscomatrix adju...
18 Years - National Institutes of Health Clinical Center (CC)
Trial With BNT111 and Cemiplimab in Combination or as Single Agents in Patients With Anti-PD-1-refractory/Relapsed, Unresectable Stage III or IV MelanomaNCT04526899
Melanoma Stage ...
Melanoma Stage ...
Unresectable Me...
BNT111
Cemiplimab
18 Years - BioNTech SE
GM-CSF Vaccinations After Allogeneic Blood Stem Cell Transplantation in Patients With Advanced Myeloid MalignanciesNCT00426205
Myelodysplastic...
Refractory Acut...
Refractory CML ...
GM-CSF secretin...
18 Years - Dana-Farber Cancer Institute
Provenge® (Sipuleucel-T) Active Cellular Immunotherapy Treatment of Metastatic Prostate Cancer After Failing Hormone TherapyNCT00065442
Prostate Cancer
Sipuleucel-T
APC-Placebo
18 Years - Dendreon
To Evaluate Sipuleucel-T Manufactured With Different Concentrations of (PA2024) AntigenNCT00715078
Prostate Cancer
sipuleucel-T
18 Years - Dendreon
GM-CSF Vaccinations After Allogeneic Blood Stem Cell Transplantation in Patients With Advanced Myeloid MalignanciesNCT00426205
Myelodysplastic...
Refractory Acut...
Refractory CML ...
GM-CSF secretin...
18 Years - Dana-Farber Cancer Institute
Sipuleucel-T Manufacturing Demonstration StudyNCT01477749
Cancer of Prost...
Cancer of the P...
Neoplasms, Pros...
Neoplasms, Pros...
Prostate Cancer
Prostate Neopla...
Prostatic Cance...
sipuleucel-T
18 Years - Dendreon
Study of NY-ESO-1 ISCOMATRIX® in Patients With Measurable Stage III or IV MelanomaNCT00518206
Melanoma
NY-ESO-1 ISCOMA...
Cyclophosphamid...
18 Years - Ludwig Institute for Cancer Research
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