Spots Global Cancer Trial Database for central nervous system
Every month we try and update this database with for central nervous system cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.
The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
| Study title | NCT ID | Conditions | Interventions | Eligibility | Organization | Link |
|---|---|---|---|---|---|---|
| Chemo-immunotherapy Using Ibrutinib Plus Indoximod for Patients With Pediatric Brain Cancer | NCT05106296 | Ependymoma Medulloblastoma Glioblastoma Primary Brain T... | Ibrutinib Indoximod Cyclophosphamid... Etoposide | 12 Years - 25 Years | Augusta University | |
| Ibrutinib Combination Therapy in Transplant Ineligible Individuals With Newly Diagnosed Primary CNS Lymphoma | NCT05998642 | Non-hodgkin Lym... | Methotrexate Rituximab (wher... Ibrutinib | 18 Years - | Canadian Cancer Trials Group | |
| Standard Dose Bevacizumab Versus Low Dose Bevacizumab Plus Lomustine (CCNU) for Recurrent Glioblastoma Multiforme (GBM) | NCT01067469 | Brain Cancer Glioblastoma | Standard Dose B... Low Dose Bevaci... Lomustine | 18 Years - | M.D. Anderson Cancer Center | |
| Liposomal Cytarabine for Central Nervous System (CNS)-Treatment in High-risk Acute Lymphoblastic Leukemia (ALL) | NCT00991744 | Acute Lymphobla... | Liposomal cytar... Intrathecal tri... | 1 Year - 18 Years | Nordic Society for Pediatric Hematology and Oncology | |
| Combined Immunochemotherapy Followed By Reduced Dose Radiation Therapy (RT) for Patients With Newly Diagnosed Primary Central Nervous System Lymphoma | NCT00594815 | Lymphoma | Cytarabine, Leu... | - | Memorial Sloan Kettering Cancer Center | |
| Monitoring for Cancer Spread to the Central Nervous System (CNS) in People With Breast Cancer | NCT05130840 | Breast Cancer | MRI Lumbar puncture | 18 Years - | Memorial Sloan Kettering Cancer Center | |
| Sodium Fluorescein-Guided Resection of Pediatric Neurosurgical Tumors | NCT03752203 | Pediatric Neuro... | Sodium Fluoresc... Microscopic Res... | 31 Days - 21 Years | University of Colorado, Denver | |
| The PRECISE Trial: Study of IL13-PE38QQR Compared to GLIADEL Wafer in Patients With Recurrent Glioblastoma Multiforme | NCT00076986 | Glioblastoma Mu... | IL13-PE38QQR surgery and cat... prolifespan 20 ... surgery and waf... | 18 Years - | INSYS Therapeutics Inc | |
| Computer-based Neurocognitive Assessment in Children With Central Nervous System Tumors Receiving Proton Beam Radiation Therapy | NCT02559752 | Central Nervous... | NIH Toolbox Cog... | 4 Years - 21 Years | Washington University School of Medicine | |
| Investigating Endothelial Precursor Cells (EPCs) | NCT00067067 | Central Nervous... | - | National Institutes of Health Clinical Center (CC) | ||
| Lenalidomide Plus R-CHOP for CNS Relapse Prophylaxis in Diffuse Large B-cell Lymphoma | NCT04544059 | Diffuse Large B... | Lenalidomide | 18 Years - 70 Years | Nanfang Hospital, Southern Medical University | |
| Monitoring for Cancer Spread to the Central Nervous System (CNS) in People With Breast Cancer | NCT05130840 | Breast Cancer | MRI Lumbar puncture | 18 Years - | Memorial Sloan Kettering Cancer Center | |
| Ibrutinib Combination Therapy in Transplant Ineligible Individuals With Newly Diagnosed Primary CNS Lymphoma | NCT05998642 | Non-hodgkin Lym... | Methotrexate Rituximab (wher... Ibrutinib | 18 Years - | Canadian Cancer Trials Group | |
| Chemo-immunotherapy Using Ibrutinib Plus Indoximod for Patients With Pediatric Brain Cancer | NCT05106296 | Ependymoma Medulloblastoma Glioblastoma Primary Brain T... | Ibrutinib Indoximod Cyclophosphamid... Etoposide | 12 Years - 25 Years | Augusta University | |
| Phase II Study to Evaluate the Combination of Rituximab and DepoCyte® in the C5R Chemotherapy Protocol in Patients Between the Ages of 18 and 60 Years With Primary Cerebral Non-Hodgkin Lymphoma and Systemic Diffuse Large B-cell Lymphoma With Neuromeningeal Invasion at Diagnosis | NCT00553943 | Lymphoma, Non-H... Diffuse Large B... | Rituximab Cytarabine | 18 Years - 60 Years | Lymphoma Study Association | |
| IL13-PE38QQR Infusion After Tumor Resection, Followed by Radiation Therapy With or Without Temozolomide in Patients With Newly Diagnosed Malignant Glioma | NCT00089427 | Glioblastoma Mu... Anaplastic Astr... Oligoastrocytom... | IL13-PE38QQR Surgery for pla... Radiation thera... Temozolomide wi... | 18 Years - | INSYS Therapeutics Inc | |
| TPI 287 in Patients With Recurrent Glioblastoma Multiforme | NCT01113463 | Brain Cancer | TPI 287 | 18 Years - | M.D. Anderson Cancer Center | |
| A Home-Based Approach Study to Evaluate the Efficacy and Safety of Alectinib in Locally-Advanced or Metastatic ALK-Positive Solid Tumors | NCT04644315 | Neoplasms Colorectal Neop... Melanoma Pancreatic Neop... Sarcoma Ovarian Neoplas... Brain Neoplasms Thyroid Neoplas... Neuroendocrine ... Cholangiocarcin... Salivary Gland ... Head and Neck N... Thyroid Cancer,... Lymphoma, Large... Neoplasms by Si... Respiratory Tra... Thoracic Neopla... Respiratory Tra... Carcinoma, Bron... Bronchial Neopl... Intestinal Neop... Gastrointestina... Digestive Syste... Digestive Syste... Gastrointestina... Colonic Disease... Intestinal Dise... Central Nervous... | Alectinib | 18 Years - | Hoffmann-La Roche | |
| Investigating Endothelial Precursor Cells (EPCs) | NCT00067067 | Central Nervous... | - | National Institutes of Health Clinical Center (CC) | ||
| Phase IB Study Using Sunitinib Plus Radiation Therapy for Cancer Patients | NCT00437372 | Cancer Head and Neck C... Pelvic Cancer Nervous System ... Thoracic Neopla... | Sunitinib External Beam R... | 18 Years - | Thomas Jefferson University | |
| Circulating microRNAs as Disease Markers in Pediatric Cancers | NCT01541800 | Leukemia Lymphoma Central Nervous... | 3 Years - 21 Years | Ann & Robert H Lurie Children's Hospital of Chicago | ||
| Treatment of Brain Metastases From Breast Cancer With Eribulin Mesylate | NCT02581839 | Metastatic Brea... Brain Metastase... | Eribulin Mesyla... MRI Pre-Medication:... Pre-Medication:... | 18 Years - | Case Comprehensive Cancer Center | |
| The PRECISE Trial: Study of IL13-PE38QQR Compared to GLIADEL Wafer in Patients With Recurrent Glioblastoma Multiforme | NCT00076986 | Glioblastoma Mu... | IL13-PE38QQR surgery and cat... prolifespan 20 ... surgery and waf... | 18 Years - | INSYS Therapeutics Inc | |
| A Study to Evaluate the Potential Increased Risk of Seizures Among Metastatic Castration-Resistant Prostate Cancer (mCRPC) Patients Treated With Enzalutamide | NCT01977651 | Metastatic Cast... | Enzalutamide | - | Astellas Pharma Inc | |
| Lenalidomide Plus R-CHOP for CNS Relapse Prophylaxis in Diffuse Large B-cell Lymphoma | NCT04544059 | Diffuse Large B... | Lenalidomide | 18 Years - 70 Years | Nanfang Hospital, Southern Medical University | |
| Identification of Risk Factors for Brain Recurrence in Patients With HER2-positive Localised Breast Cancer | NCT06358625 | HER2-positive B... | Pre-treatment b... | 18 Years - | Center Eugene Marquis | |
| Investigating Endothelial Precursor Cells (EPCs) | NCT00067067 | Central Nervous... | - | National Institutes of Health Clinical Center (CC) | ||
| Standard Dose Bevacizumab Versus Low Dose Bevacizumab Plus Lomustine (CCNU) for Recurrent Glioblastoma Multiforme (GBM) | NCT01067469 | Brain Cancer Glioblastoma | Standard Dose B... Low Dose Bevaci... Lomustine | 18 Years - | M.D. Anderson Cancer Center | |
| Imaging Brain Tumors With FACBC and Methionine | NCT00597246 | Brain Cancer CNS Cancer | FACBC, Methioni... PET Scan | - | Memorial Sloan Kettering Cancer Center | |
| Imaging Brain Tumors With FACBC and Methionine | NCT00597246 | Brain Cancer CNS Cancer | FACBC, Methioni... PET Scan | - | Memorial Sloan Kettering Cancer Center | |
| A Home-Based Approach Study to Evaluate the Efficacy and Safety of Alectinib in Locally-Advanced or Metastatic ALK-Positive Solid Tumors | NCT04644315 | Neoplasms Colorectal Neop... Melanoma Pancreatic Neop... Sarcoma Ovarian Neoplas... Brain Neoplasms Thyroid Neoplas... Neuroendocrine ... Cholangiocarcin... Salivary Gland ... Head and Neck N... Thyroid Cancer,... Lymphoma, Large... Neoplasms by Si... Respiratory Tra... Thoracic Neopla... Respiratory Tra... Carcinoma, Bron... Bronchial Neopl... Intestinal Neop... Gastrointestina... Digestive Syste... Digestive Syste... Gastrointestina... Colonic Disease... Intestinal Dise... Central Nervous... | Alectinib | 18 Years - | Hoffmann-La Roche | |
| Treatment of Brain Metastases From Breast Cancer With Eribulin Mesylate | NCT02581839 | Metastatic Brea... Brain Metastase... | Eribulin Mesyla... MRI Pre-Medication:... Pre-Medication:... | 18 Years - | Case Comprehensive Cancer Center | |
| Standard Dose Bevacizumab Versus Low Dose Bevacizumab Plus Lomustine (CCNU) for Recurrent Glioblastoma Multiforme (GBM) | NCT01067469 | Brain Cancer Glioblastoma | Standard Dose B... Low Dose Bevaci... Lomustine | 18 Years - | M.D. Anderson Cancer Center | |
| Phase IB Study Using Sunitinib Plus Radiation Therapy for Cancer Patients | NCT00437372 | Cancer Head and Neck C... Pelvic Cancer Nervous System ... Thoracic Neopla... | Sunitinib External Beam R... | 18 Years - | Thomas Jefferson University | |
| Phase IB Study Using Sunitinib Plus Radiation Therapy for Cancer Patients | NCT00437372 | Cancer Head and Neck C... Pelvic Cancer Nervous System ... Thoracic Neopla... | Sunitinib External Beam R... | 18 Years - | Thomas Jefferson University | |
| SCRI Tissue Testing Registry | NCT00965861 | Melanoma Myelodysplastic... Multiple Myelom... Lymphoma | Tissue Registry... | 18 Years - | SCRI Development Innovations, LLC | |
| Vinblastine and Temsirolimus in Pediatrics With Recurrent or Refractory Lymphoma or Solid Tumours Including CNS Tumours | NCT02343718 | Recurrent Lymph... Refractory Lymp... Solid Tumours Central Nervous... | Vinblastine Temsirolimus | 1 Year - 18 Years | Canadian Cancer Trials Group | |
| Selinexor, Pomalidomide, and Dexamethasone For Multiple Myeloma With CNS Involvement | NCT05478993 | Multiple Myelom... | SPD：Selinexor O... | 18 Years - | Peking University People's Hospital | |
| Sodium Fluorescein-Guided Resection of Pediatric Neurosurgical Tumors | NCT03752203 | Pediatric Neuro... | Sodium Fluoresc... Microscopic Res... | 31 Days - 21 Years | University of Colorado, Denver | |
| Imaging Brain Tumors With FACBC and Methionine | NCT00597246 | Brain Cancer CNS Cancer | FACBC, Methioni... PET Scan | - | Memorial Sloan Kettering Cancer Center | |
| Prospective Cohort Study With Central Nervous System Evaluation in Diffuse Large B-cell Lymphoma | NCT01202448 | Diffuse Large B... | CSF analysis | 20 Years - | Samsung Medical Center | |
| Sorafenib, Valproic Acid, and Sildenafil in Treating Patients With Recurrent High-Grade Glioma | NCT01817751 | Glioblastoma Recurrent Adult... Malignant Gliom... WHO Grade III G... | sorafenib tosyl... valproic acid sildenafil citr... | 18 Years - | Virginia Commonwealth University | |
| Combined Immunochemotherapy Followed By Reduced Dose Radiation Therapy (RT) for Patients With Newly Diagnosed Primary Central Nervous System Lymphoma | NCT00594815 | Lymphoma | Cytarabine, Leu... | - | Memorial Sloan Kettering Cancer Center | |
| Selinexor, Pomalidomide, and Dexamethasone For Multiple Myeloma With CNS Involvement | NCT05478993 | Multiple Myelom... | SPD：Selinexor O... | 18 Years - | Peking University People's Hospital | |
| Phase II Study to Evaluate the Combination of Rituximab and DepoCyte® in the C5R Chemotherapy Protocol in Patients Between the Ages of 18 and 60 Years With Primary Cerebral Non-Hodgkin Lymphoma and Systemic Diffuse Large B-cell Lymphoma With Neuromeningeal Invasion at Diagnosis | NCT00553943 | Lymphoma, Non-H... Diffuse Large B... | Rituximab Cytarabine | 18 Years - 60 Years | Lymphoma Study Association | |
| Monitoring for Cancer Spread to the Central Nervous System (CNS) in People With Breast Cancer | NCT05130840 | Breast Cancer | MRI Lumbar puncture | 18 Years - | Memorial Sloan Kettering Cancer Center | |
| Central Nervous System (CNS) Involvement in Acute Myeloid Leukemia (AML) | NCT03410407 | Acute Myeloid L... | Observation of ... | 18 Years - | Gruppo Italiano Malattie EMatologiche dell'Adulto | |
| Vinblastine and Temsirolimus in Pediatrics With Recurrent or Refractory Lymphoma or Solid Tumours Including CNS Tumours | NCT02343718 | Recurrent Lymph... Refractory Lymp... Solid Tumours Central Nervous... | Vinblastine Temsirolimus | 1 Year - 18 Years | Canadian Cancer Trials Group | |
| Identification of Risk Factors for Brain Recurrence in Patients With HER2-positive Localised Breast Cancer | NCT06358625 | HER2-positive B... | Pre-treatment b... | 18 Years - | Center Eugene Marquis | |
| Treatment of Brain Metastases From Breast Cancer With Eribulin Mesylate | NCT02581839 | Metastatic Brea... Brain Metastase... | Eribulin Mesyla... MRI Pre-Medication:... Pre-Medication:... | 18 Years - | Case Comprehensive Cancer Center |
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