Spots Global Cancer Trial Database for glioma, malignant
Every month we try and update this database with for glioma, malignant cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.
The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
Study title | NCT ID | Conditions | Interventions | Eligibility | Organization | Link |
---|---|---|---|---|---|---|
Neoantigens Phase I Trial in Newly Diagnosed Glioblastoma Patients | NCT05557240 | Glioma, Maligna... Antigen-specifi... Individualized ... | NeoPep Vaccine1... NeoPep Vaccine2... | 18 Years - 70 Years | Shanghai 10th People's Hospital | |
Concurrent Fluorescence and Sonographically Guided Eradication of Contrast-enhancing Gliomas and Metastases | NCT05474573 | Glioma, Maligna... Metastases to B... | Combined ultras... Fluorescence-gu... | 18 Years - 79 Years | Sklifosovsky Institute of Emergency Care | |
Evaluate the Safety and Effectiveness of Intranasal Administration of Temozolomide in Patients With Glioblastoma | NCT04091503 | Glioma, Maligna... Gliosarcoma Astrocytoma of ... | Intranasal Modi... | 21 Years - 70 Years | Center Trials & Treatment Europe | |
Surgical Tissue Flap to Bypass the Blood Brain Barrier in Glioblastoma | NCT05954858 | Glioma, Maligna... Glioblastoma Glioblastoma Mu... Glioblastoma Mu... High Grade Glio... GBM Brain Cancer | Tissue autograf... | 18 Years - | Northwell Health | |
18F-Fluciclovine PET-MRI in High-grade Glioma | NCT05553041 | Glioma High Grade Glio... Glioma, Maligna... Glioma Intracra... Diffuse Glioma | 18F-Fluciclovin... | 1 Year - 21 Years | Children's Hospital of Philadelphia | |
Evaluation of 18F-Fluciclovine Positron Emission Tomography - Magnetic Resonance Imaging (PET-MRI) in LGG | NCT05555550 | Glioma Low-grade Gliom... Low Grade Gliom... Glioma, Maligna... Glioma Intracra... | 18F-Fluciclovin... | 1 Year - 21 Years | Children's Hospital of Philadelphia | |
Role of Surgery in Treatment of Recurrent Brian Glioma:Prognostic Factors and Outcome | NCT04562077 | Recurrent Gliom... Glioma, Maligna... | - | Assiut University | ||
Study of NUV-422 in Adults With Recurrent or Refractory High-grade Gliomas and Solid Tumors | NCT04541225 | Glioma Glioma, Maligna... Glioma, Mixed Glial Cell Tumo... Breast Cancer Breast Carcinom... Cancer of Breas... Cancer of the B... Breast Tumor Malignant Tumor... Advanced Breast... Advanced Breast... Metastatic Brea... Metastatic Brea... Prostate Cancer Prostatic Cance... Cancer of Prost... Cancer of the P... Prostate Neopla... Castrate Resist... Castration-resi... Castration Resi... Glioblastoma Recurrent Gliob... | NUV-422 | 18 Years - | Nuvation Bio Inc. | |
Intraoperative Rapid Diagnosis of Glioma Based on Fusion of Magnetic Resonance and Ultrasound Imaging | NCT05656053 | Glioma, Maligna... Computer-Assist... | 18 Years - 80 Years | Mingge LLC | ||
Superselective Intra-arterial Cerebral Infusion of Temsirolimus in HGG | NCT05773326 | High Grade Glio... Glioma Glioma, Maligna... Glioblastoma | Temsirolimus | 18 Years - | St. Joseph's Hospital and Medical Center, Phoenix | |
An Integrated Radio-immunological Approach | NCT05267509 | Glioma, Maligna... | 18 Years - 80 Years | Istituto Oncologico Veneto IRCCS | ||
Effect of Perampanel on Peritumoral Hyperexcitability in HGG | NCT04497142 | Glioma, Maligna... Surgery Seizures | Perampanel Standard of Car... | 18 Years - | Dana-Farber Cancer Institute | |
Glioblastoma and Individualized Therapies | NCT05356312 | Glioma, Maligna... | Vaccination | - | Zentrum fur Humangenetik Tuebingen | |
Clinical Evaluation of Genetron IDH1 PCR Kit in Glioma Patients | NCT05100173 | Glioma, Maligna... Glioma, Mixed | - | Genetron Health | ||
Repeated Superselective Intraarterial Cerebral Infusion (SIACI) of Bevacizumab With Temozolomide and Radiation Compared to Temozolomide and Radiation Alone in Newly Diagnosed GBM | NCT05271240 | Glioblastoma Glioblastoma Mu... Glioma, Maligna... GBM Brain Cancer Glioblastoma, I... Glioblastoma Mu... | Repeated Supers... Temozolomide an... | 18 Years - | Northwell Health | |
General Anesthesia Versus Awake Surgery in Resection of Gliomas and Metastases of Motor Areas | NCT05485038 | Gliomas Benign Glioma, Maligna... Metastases to B... | Tumor resection... Tumor resection... | 18 Years - 69 Years | Sklifosovsky Institute of Emergency Care | |
Trial of Niraparib in Participants With Newly-diagnosed Glioblastoma and Recurrent Glioma | NCT05076513 | Glioblastoma Glioblastoma Mu... Glioma GBM Glioma, Maligna... Glioblastoma Mu... | Niraparib Radiation thera... | 18 Years - | St. Joseph's Hospital and Medical Center, Phoenix | |
Repeated Superselective Intraarterial Cerebral Infusion (SIACI) of Bevacizumab With Temozolomide and Radiation Compared to Temozolomide and Radiation Alone in Newly Diagnosed GBM | NCT05271240 | Glioblastoma Glioblastoma Mu... Glioma, Maligna... GBM Brain Cancer Glioblastoma, I... Glioblastoma Mu... | Repeated Supers... Temozolomide an... | 18 Years - | Northwell Health | |
Integrated Analysis of Therapy Response and Resistence in Embryonal Tumors and Gliomas | NCT06323408 | Glioma, Maligna... Embryonal Tumor Medulloblastoma Ependymoma | Tissue, blood, ... | 15 Years - 39 Years | University Hospital Regensburg | |
Evaluate the Safety and Effectiveness of Intranasal Administration of Temozolomide in Patients With Glioblastoma | NCT04091503 | Glioma, Maligna... Gliosarcoma Astrocytoma of ... | Intranasal Modi... | 21 Years - 70 Years | Center Trials & Treatment Europe | |
Grafts of GSCs Into Brain Organoids for Testing Anti-invasion Drugs | NCT05772741 | Glioblastoma Glioma, Maligna... | Biological samp... | 18 Years - | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | |
HSRT and IMRT Chemoradiotherapy for Newly Diagnosed GBM | NCT04547621 | Glioma, Maligna... | Radiation Radiation Temozolomide | 18 Years - 70 Years | Huashan Hospital | |
ONC201 in Pediatric H3 K27M Gliomas | NCT03416530 | Diffuse Intrins... Glioma, Maligna... | ONC201 | 2 Years - 18 Years | Chimerix | |
Phase 1 Trial of D2C7-IT in Combination With 2141-V11 for Recurrent Malignant Glioma | NCT04547777 | Glioma, Maligna... | D2C7-IT 2141-V11 | 18 Years - | Duke University | |
Glioma: Biomolecular Aspects | NCT05806619 | Glioma, Maligna... | histopathologic... | - | Regina Elena Cancer Institute | |
Grafts of GSCs Into Brain Organoids for Testing Anti-invasion Drugs | NCT05772741 | Glioblastoma Glioma, Maligna... | Biological samp... | 18 Years - | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | |
5-Aminolevulinic Acid (5-ALA) Gliolan®: Usage Increase Proposal for Neurosurgical Procedures in High-Grade Gliomas | NCT05850377 | High Grade Glio... Glioma Glioma, Maligna... Neoplasms, Neur... Neuroectodermal... Photosensitizin... Neoplasm Malign... Brain Neoplasms... Central Nervous... Brain Tumor Tumour, Residua... | 5-Aminolevulini... Fluorescence-Gu... | 18 Years - 75 Years | Sociedad de Lucha Contra el Cáncer del Ecuador | |
Social Cognition and Language in Patients With Gliomas | NCT05764460 | Glioma, Maligna... Cognitive Dysfu... | Neuropsychologi... | 18 Years - | University Medical Center Groningen | |
Clinical Evaluation of Genetron TERT PCR Kit in Glioma Patients | NCT05100602 | Glioma, Maligna... | - | Genetron Health | ||
Surgical Tissue Flap to Bypass the Blood Brain Barrier in Glioblastoma | NCT05954858 | Glioma, Maligna... Glioblastoma Glioblastoma Mu... Glioblastoma Mu... High Grade Glio... GBM Brain Cancer | Tissue autograf... | 18 Years - | Northwell Health | |
Prospective Evaluation of AI R&D Tool in Adult Glioma and Other Primary Brain Tumours (PEAR-GLIO) | NCT06038760 | Brain Tumor Glioma, Maligna... Ependymoma Oligodendroglio... Glioblastoma | Resection | 18 Years - | Ourotech, Inc. | |
GMCI, Nivolumab, and Radiation Therapy in Treating Patients With Newly Diagnosed High-Grade Gliomas | NCT03576612 | Glioma, Maligna... | AdV-tk Valacyclovir Radiation Temozolomide Nivolumab Laboratory Biom... | 18 Years - | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | |
General Anesthesia Versus Awake Surgery in Resection of Gliomas and Metastases of Motor Areas | NCT05485038 | Gliomas Benign Glioma, Maligna... Metastases to B... | Tumor resection... Tumor resection... | 18 Years - 69 Years | Sklifosovsky Institute of Emergency Care | |
Personalized Rendering of Motor System Functional Plasticity Potential to Improve Glioma Resection and Quality of Life | NCT06381726 | Glioma Glioma, Maligna... | Resting State F... Up-front Motor ... Up-front Chemot... | 18 Years - | University of Milan | |
Niraparib and Temozolomide in Patients Glioblastoma | NCT06258018 | Glioma, Maligna... | Temodal Niraparib | 18 Years - | Istituto Clinico Humanitas | |
Multi-center Research Project for Glioma Molecular Pathology Intraoperative Rapid Detection | NCT04904419 | Glioma, Maligna... | Intraoperative ... | 18 Years - 80 Years | Huashan Hospital | |
Safety and Tolerability of Fb-PMT in Recurrent Glioblastoma | NCT05226494 | Glioma, Maligna... | fb-PMT | 18 Years - | NanoPharmaceuticals LLC | |
18F-Fluciclovine PET-MRI in High-grade Glioma | NCT05553041 | Glioma High Grade Glio... Glioma, Maligna... Glioma Intracra... Diffuse Glioma | 18F-Fluciclovin... | 1 Year - 21 Years | Children's Hospital of Philadelphia | |
Laparoscopically Harvested Omental Free Tissue Autograft to Bypass the Blood Brain Barrier (BBB) in Human Recurrent Glioblastoma Multiforme (rGBM) | NCT04222309 | Glioma Glioma, Maligna... Glioblastoma Glioblastoma Mu... Glioblastoma Mu... GBM Brain Cancer | Laparoscopicall... | 18 Years - | Northwell Health | |
Neoantigens Phase I Trial in Newly Diagnosed Glioblastoma Patients | NCT05557240 | Glioma, Maligna... Antigen-specifi... Individualized ... | NeoPep Vaccine1... NeoPep Vaccine2... | 18 Years - 70 Years | Shanghai 10th People's Hospital | |
PrOton Pulsed reduCed dOse Rate Radiotherapy for Recurrent CNS maligNancies Trial | NCT06397560 | Glioma Glioma, Maligna... Recurrent Gliom... | PRDR | 18 Years - | Baptist Health South Florida | |
Study of NUV-422 in Adults With Recurrent or Refractory High-grade Gliomas and Solid Tumors | NCT04541225 | Glioma Glioma, Maligna... Glioma, Mixed Glial Cell Tumo... Breast Cancer Breast Carcinom... Cancer of Breas... Cancer of the B... Breast Tumor Malignant Tumor... Advanced Breast... Advanced Breast... Metastatic Brea... Metastatic Brea... Prostate Cancer Prostatic Cance... Cancer of Prost... Cancer of the P... Prostate Neopla... Castrate Resist... Castration-resi... Castration Resi... Glioblastoma Recurrent Gliob... | NUV-422 | 18 Years - | Nuvation Bio Inc. | |
ETAPA I: Peptide-based Tumor Associated Antigen Vaccine in GBM | NCT05283109 | Glioma, Maligna... | Tumor Associate... Hiltonol | 18 Years - | Duke University | |
GRETeL: Tumor Response to Standard Radiotherapy and TMZ Patients With GBM | NCT05695976 | Glioblastoma Glioma, Maligna... | 18 Years - | Duke University | ||
AZD1390 in Recurrent and Newly Diagnosed WHO Grade 4 Glioma Patients | NCT05182905 | Glioblastoma Glioma Glioblastoma Mu... Glioma, Maligna... | AZD1390 | 18 Years - | St. Joseph's Hospital and Medical Center, Phoenix | |
Molecular Pathology Research Project of Glioma | NCT04924127 | Glioma, Maligna... | Detection of ID... | 18 Years - 80 Years | Huashan Hospital | |
Incidence of Intracranial Hemorrhage in Glioma Patients With Venous Thromboembolism Converted From LMWH to Apixaban | NCT04895553 | Glioma, Maligna... | Observation of ... | 18 Years - | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | |
Omental Tissue Autograft in Human Recurrent Glioblastoma Multiforme (rGBM) | NCT05979064 | Glioma Glioma, Maligna... Glioblastoma Glioblastoma Mu... Glioblastoma Mu... GBM Brain Cancer High Grade Glio... | Laparoscopicall... | 18 Years - | Northwell Health | |
Repeated Neural Stem Cell Based Virotherapy for Newly Diagnosed High Grade Glioma | NCT06169280 | Glioma, Maligna... New Diagnosis T... | NSC-CRAd-S-pk7 N-acetylcystein... | 18 Years - | Northwestern University | |
Combination of Immunization and Radiotherapy for Malignant Gliomas (InSituVac1) | NCT03392545 | High Grade Glio... Glioblastoma Glioma of Brain... Glioma, Maligna... | Combined immune... | 18 Years - 65 Years | Beijing Tiantan Hospital | |
Assessing the Effectiveness of 2D Non-Navigated Intraoperative Ultrasound in Glioma Surgery | NCT05873946 | Glioma Glioma, Maligna... Low-grade Gliom... High-grade Glio... Glioblastoma | intraoperative ... | 18 Years - 80 Years | Hospital del Río Hortega | |
Modulation of Ciliogenesis in Glioma Stem Cells | NCT05772767 | Glioblastoma Glioma, Maligna... | Biological samp... Dissecting cili... Validating cili... | 18 Years - | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | |
Modulation of Ciliogenesis in Glioma Stem Cells | NCT05772767 | Glioblastoma Glioma, Maligna... | Biological samp... Dissecting cili... Validating cili... | 18 Years - | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | |
Phase 1 Trial of D2C7-IT in Combination With 2141-V11 for Recurrent Malignant Glioma | NCT04547777 | Glioma, Maligna... | D2C7-IT 2141-V11 | 18 Years - | Duke University | |
General Anesthesia Versus Awake Surgery in Resection of Gliomas and Metastases of Motor Areas | NCT05485038 | Gliomas Benign Glioma, Maligna... Metastases to B... | Tumor resection... Tumor resection... | 18 Years - 69 Years | Sklifosovsky Institute of Emergency Care | |
ERC1671 to Treat Malignant Gliomas When Given in Combination With GM-CSF, Cyclophosphamide, Bevacizumab and Pembrolizumab | NCT05366062 | Glioma, Maligna... | ERC1671 GM-CSF Cyclophosphamid... Pembrolizumab | 18 Years - | Epitopoietic Research Corporation | |
Superselective Intra-arterial Cerebral Infusion of Temsirolimus in HGG | NCT05773326 | High Grade Glio... Glioma Glioma, Maligna... Glioblastoma | Temsirolimus | 18 Years - | St. Joseph's Hospital and Medical Center, Phoenix | |
Temporally-modulated Pulsed Radiation Therapy (TMPRT) After Prior EBRT for Recurrent IDH-mutant Gliomas | NCT05393258 | Astrocytoma Oligodendroglio... Glioma, Maligna... | temporally-modu... | 18 Years - | Washington University School of Medicine | |
Radiomics-Based Visualization and Quantitative Validation of IDH1 Heterogeneity in Gliomas | NCT05969691 | Glioma, Maligna... Computer-Assist... | Validation of I... | 18 Years - 80 Years | Mingge LLC | |
Establishing Radiolabelled PSMA as a Target for Glioma Treatment | NCT05263466 | Glioma, Maligna... | PET-MRI Brain tumour bi... | 18 Years - | King's College Hospital NHS Trust | |
Assessment of Safety and Feasibility of ExAblate Blood-Brain Barrier (BBB) Disruption in GBM Patients | NCT04998864 | Glioma, Maligna... Glioblastoma | Magnetic Resona... | 18 Years - 80 Years | InSightec | |
Neoantigens Phase I Trial in Newly Diagnosed Glioblastoma Patients | NCT05557240 | Glioma, Maligna... Antigen-specifi... Individualized ... | NeoPep Vaccine1... NeoPep Vaccine2... | 18 Years - 70 Years | Shanghai 10th People's Hospital | |
Repeated Neural Stem Cell Based Virotherapy for Newly Diagnosed High Grade Glioma | NCT06169280 | Glioma, Maligna... New Diagnosis T... | NSC-CRAd-S-pk7 N-acetylcystein... | 18 Years - | Northwestern University | |
Repeated Superselective Intraarterial Cerebral Infusion (SIACI) of Bevacizumab With Temozolomide and Radiation Compared to Temozolomide and Radiation Alone in Newly Diagnosed GBM | NCT05271240 | Glioblastoma Glioblastoma Mu... Glioma, Maligna... GBM Brain Cancer Glioblastoma, I... Glioblastoma Mu... | Repeated Supers... Temozolomide an... | 18 Years - | Northwell Health |