Spots Global Cancer Trial Database for gliomas
Every month we try and update this database with for gliomas cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.
The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
| Study title | NCT ID | Conditions | Interventions | Eligibility | Organization | Link |
|---|---|---|---|---|---|---|
| Temozolomide & RT Followed by Dose Dense vs Temozolomide & Retinoic Acid in Pts w/Glioblastoma | NCT00200161 | Glioblastoma Gliomas | Temozolomide Temozolomide | 18 Years - 70 Years | Memorial Sloan Kettering Cancer Center | |
| Nivolumab for Recurrent or Progressive IDH Mutant Gliomas | NCT03557359 | Gliomas | Nivolumab | 18 Years - | Columbia University | |
| A Study of the Specificity and Sensitivity of 5-ALA Fluorescence in Malignant Brain Tumors | NCT00977795 | Brain Neoplasms | 5-aminolevulini... | 18 Years - | NorthShore University HealthSystem | |
| Rare CNS Tumors Outcomes &Risk | NCT03251989 | High Grade Meni... Ependymoma Medulloblastoma PNET Primary CNS Sar... | 18 Years - | National Institutes of Health Clinical Center (CC) | ||
| Intraoperative Rapid Diagnosis of Glioma Based on Fusion of Magnetic Resonance and Ultrasound Imaging | NCT05656053 | Glioma, Maligna... Computer-Assist... | 18 Years - 80 Years | Mingge LLC | ||
| Temozolomide & RT Followed by Dose Dense vs Temozolomide & Retinoic Acid in Pts w/Glioblastoma | NCT00200161 | Glioblastoma Gliomas | Temozolomide Temozolomide | 18 Years - 70 Years | Memorial Sloan Kettering Cancer Center | |
| Study to Evaluate the Efficacy and Safety of Pemigatinib in Participants With Previously Treated Glioblastoma or Other Primary Central Nervous System Tumors Harboring Activating FGFR1-3 Alterations | NCT05267106 | Glioblastoma Adult-type Diff... | Pemigatinib | 18 Years - 99 Years | Incyte Corporation | |
| A Study of the Specificity and Sensitivity of 5- Aminolevulinic Acid (ALA) Fluorescence in Malignant Brain Tumors | NCT01128218 | Brain Neoplasms | Tumor fluoresce... | 18 Years - | Southern Illinois University | |
| Efficacy of Tranexamic Acid in Brain Tumor Resections | NCT01655927 | Brain Tumors Neoplasms Gliomas Astrocytomas Meningiomas | Tranexamic Acid Placebo: Saline | 18 Years - 65 Years | Colombian Foundation for Epilepsy and Neurological Disease | |
| EGFR Inhibition Using Weekly Erlotinib for Recurrent Malignant Gliomas | NCT01257594 | Brain Cancer | erlotinib Cytoreductive S... | 18 Years - | Columbia University | |
| Multimodality Imaging Combined With Multiple Targets Pathological Examination for Detecting of Biological Borders of Gliomas: a Clinical Application Study | NCT02941302 | Glioma | Detecting of Bi... | - | General Hospital of Ningxia Medical University | |
| Genetic Analysis of Brain Tumors | NCT00031538 | Glioma Glioblastoma Mu... Anaplastic Astr... Oligodendroglio... Astrocytoma | 1 Year - 99 Years | National Institutes of Health Clinical Center (CC) | ||
| Observational Study for Assessing Treatment and Outcome of Patients With Primary Brain Tumours Using cIMPACT-NOW and 2021 WHO Classification | NCT05259605 | Glioma Glioneuronal Tu... Choroid Plexus ... Pineal Tumors Germ Cell Tumor Tumor of the Se... Diffuse Midline... Ependymoma Embryonal Tumor Pineal Tumor Hemangiopericyt... Hemangioblastom... Melanocytic Tum... | Observational | 18 Years - | European Organisation for Research and Treatment of Cancer - EORTC | |
| Advanced MR Techniques in Detection of Tumor Infiltration and Grading in Gliomas | NCT01225003 | Gliomas | 18 Years - | Universitaire Ziekenhuizen KU Leuven | ||
| More Complete Removal of Malignant Brain Tumors by Fluorescence-Guided Surgery | NCT01445691 | Benign Neoplasm... Brain Cancer Brain Neoplasms... Brain Neoplasms... Brain Tumor, Pr... Brain Tumor, Re... Brain Tumors Intracranial Ne... Neoplasms, Brai... Neoplasms, Intr... Primary Brain N... Primary Maligna... Primary Maligna... Gliomas Glioblastoma | 5-ALA (Gliolan) | 18 Years - 80 Years | Icahn School of Medicine at Mount Sinai | |
| Cellular Immunotherapy Study for Brain Cancer | NCT01144247 | Gliomas Anaplastic Astr... Anaplastic Olig... Anaplastic Mixe... Glioblastoma Mu... Malignant Menin... | alloreactive CT... | 18 Years - | Jonsson Comprehensive Cancer Center | |
| Dose Escalation Study of Vandetanib With Hypofractionated Stereotactic Radiotherapy in Recurrent Malignant Gliomas | NCT00822887 | Malignant Gliom... | Vandetanib Fractionated St... | 18 Years - | University of Colorado, Denver | |
| Cilengitide and Metronomic Temozolomide for Relapsed or Refractory High Grade Gliomas or Diffuse Intrinsic Pontine Gliomas in Children and Adolescents | NCT01517776 | Gliomas | Cilengitide Temozolomide | 3 Years - 17 Years | Martin-Luther-Universität Halle-Wittenberg | |
| (11C)dLop as a Marker of P-Glycoprotein Function in Patients With Gliomas | NCT01281982 | Low Grade Gliom... Glioblastoma Mu... Anaplastic Astr... Anaplastic Olig... Oligoastrocytom... | 18 Years - 99 Years | National Institutes of Health Clinical Center (CC) | ||
| 177Lu-J591 Antibody in Patients With Nonprostate Metastatic Solid Tumors | NCT00967577 | Kidney Cancer Head and Neck C... Breast Cancer Non-small Cell ... Colorectal Canc... Pancreatic Canc... Ovarian Cancer Esophageal Canc... Gliomas | 177Lu-J591 | 18 Years - | Weill Medical College of Cornell University | |
| Expanded Access Program for Avapritinib | NCT04714086 | Solid Tumors | Avapritinib | 18 Years - | Blueprint Medicines Corporation | |
| A Phase I Study of High-dose L-methylfolate in Combination With Temozolomide and Bevacizumab in Recurrent High Grade Glioma | NCT01891747 | Malignant Gliom... | Bevacizumab Temozolomide Vitamin C | 18 Years - | Vanderbilt-Ingram Cancer Center | |
| Study to Evaluate the Efficacy and Safety of Pemigatinib in Participants With Previously Treated Glioblastoma or Other Primary Central Nervous System Tumors Harboring Activating FGFR1-3 Alterations | NCT05267106 | Glioblastoma Adult-type Diff... | Pemigatinib | 18 Years - 99 Years | Incyte Corporation | |
| Irinotecan in Combination With Cisplatin in Pediatric Patients With Unfavorable Prognosis Gliomas | NCT01574092 | Pediatric High ... | Combination of ... | 6 Months - 18 Years | Hospital Sant Joan de Deu | |
| Clinical Trial of the Use of the Nasal Spray of Patients With Recurrence of Glioblastoma | NCT03275558 | Recurrent Gliob... Gliosarcoma Anaplastic Glio... | Axitinib 1 MG Sunitinib 5 MG Pazopanib 5 MG | 18 Years - 80 Years | Center Trials & Treatment | |
| A Pilot Study of Inpatient Hospice With Procurement of Brain Tumor Tissue on Expiration for Research Purposes | NCT01251913 | Ependymomas Gliomas PNET Pineal Tumors PCNSL (Primary ... | 18 Years - 100 Years | National Institutes of Health Clinical Center (CC) | ||
| A Pilot Study of Inpatient Hospice With Procurement of Brain Tumor Tissue on Expiration for Research Purposes | NCT01251913 | Ependymomas Gliomas PNET Pineal Tumors PCNSL (Primary ... | 18 Years - 100 Years | National Institutes of Health Clinical Center (CC) | ||
| Cellular Immunotherapy Study for Brain Cancer | NCT01144247 | Gliomas Anaplastic Astr... Anaplastic Olig... Anaplastic Mixe... Glioblastoma Mu... Malignant Menin... | alloreactive CT... | 18 Years - | Jonsson Comprehensive Cancer Center | |
| Study of Laser Interstitial Thermal Therapy (LITT) Treatment Response Assessment With Fluciclovine PET MR | NCT05054400 | Brain Metastase... Cancer Gliomas Glioblastoma | F18 Fluciclovin... Standard of Car... | 18 Years - | M.D. Anderson Cancer Center | |
| A Phase II Study of Adjuvant Use of Anti-Epidermal Growth Factor Receptor EGFR-425 in High Grade Gliomas | NCT00589706 | Gliomas | MAb-425 | 18 Years - | Drexel University | |
| Intra-operative Variation in Size of Brain Tumors After Craniotomy | NCT04365647 | Brain Tumor, Pr... | 15 Years - 75 Years | Sheri Kashmir Institute of Medical Sciences | ||
| Efficacy of Tranexamic Acid in Brain Tumor Resections | NCT01655927 | Brain Tumors Neoplasms Gliomas Astrocytomas Meningiomas | Tranexamic Acid Placebo: Saline | 18 Years - 65 Years | Colombian Foundation for Epilepsy and Neurological Disease | |
| Combination of Immunization and Radiotherapy for Malignant Gliomas (InSituVac1) | NCT03392545 | High Grade Glio... Glioblastoma Glioma of Brain... Glioma, Maligna... | Combined immune... | 18 Years - 65 Years | Beijing Tiantan Hospital | |
| Intra-operative Variation in Size of Brain Tumors After Craniotomy | NCT04365647 | Brain Tumor, Pr... | 15 Years - 75 Years | Sheri Kashmir Institute of Medical Sciences | ||
| Nivolumab for Recurrent or Progressive IDH Mutant Gliomas | NCT03557359 | Gliomas | Nivolumab | 18 Years - | Columbia University | |
| [18F] FACBC and [18F] FLT PET Imaging in Central Nervous System Tumors | NCT00832598 | Brain Cancer Gliomas | [18F]FACBC PET ... | 18 Years - | Memorial Sloan Kettering Cancer Center | |
| Irinotecan in Combination With Cisplatin in Pediatric Patients With Unfavorable Prognosis Gliomas | NCT01574092 | Pediatric High ... | Combination of ... | 6 Months - 18 Years | Hospital Sant Joan de Deu | |
| Observational Study for Assessing Treatment and Outcome of Patients With Primary Brain Tumours Using cIMPACT-NOW and 2021 WHO Classification | NCT05259605 | Glioma Glioneuronal Tu... Choroid Plexus ... Pineal Tumors Germ Cell Tumor Tumor of the Se... Diffuse Midline... Ependymoma Embryonal Tumor Pineal Tumor Hemangiopericyt... Hemangioblastom... Melanocytic Tum... | Observational | 18 Years - | European Organisation for Research and Treatment of Cancer - EORTC | |
| Rare CNS Tumors Outcomes &Risk | NCT03251989 | High Grade Meni... Ependymoma Medulloblastoma PNET Primary CNS Sar... | 18 Years - | National Institutes of Health Clinical Center (CC) | ||
| Phase I/II: Decitabine/Vaccine Therapy in Relapsed/Refractory Pediatric High Grade Gliomas/Medulloblastomas/CNS PNETs | NCT02332889 | Gliomas Medulloblastoma Neuroectodermal... | Vaccine (autolo... Decitabine and ... | 2 Years - 25 Years | University of Louisville | |
| Genetic Analysis of Brain Tumors | NCT00031538 | Glioma Glioblastoma Mu... Anaplastic Astr... Oligodendroglio... Astrocytoma | 1 Year - 99 Years | National Institutes of Health Clinical Center (CC) | ||
| Radiomics-Based Visualization and Quantitative Validation of IDH1 Heterogeneity in Gliomas | NCT05969691 | Glioma, Maligna... Computer-Assist... | Validation of I... | 18 Years - 80 Years | Mingge LLC | |
| Chronic Convection Enhanced Delivery of Topotecan | NCT03154996 | Gliomas | Topotecan Gadolinium Synchromed II i... | 18 Years - | Columbia University | |
| Studying the Biology of IDH-mutant Gliomas Via Longitudinal Observation of 2-hydroxyglutarate (2-HG) Using MR Spectroscopy | NCT03952598 | Glioma Gliomas High Grade Glio... Malignant Gliom... Low Grade Gliom... | 3T MRI scanner | 18 Years - | National Institutes of Health Clinical Center (CC) | |
| Expanded Access Program for Avapritinib | NCT04714086 | Solid Tumors | Avapritinib | 18 Years - | Blueprint Medicines Corporation | |
| Window-of-Opportunity Trial of Ulixertinib for MAPK-Activated Low-Grade Gliomas in Adults | NCT05804227 | Gliomas | Ulixertinib | 18 Years - | M.D. Anderson Cancer Center | |
| A Study of the Specificity and Sensitivity of 5-ALA Fluorescence in Malignant Brain Tumors | NCT00977795 | Brain Neoplasms | 5-aminolevulini... | 18 Years - | NorthShore University HealthSystem | |
| Advanced MR Techniques in Detection of Tumor Infiltration and Grading in Gliomas | NCT01225003 | Gliomas | 18 Years - | Universitaire Ziekenhuizen KU Leuven | ||
| A Phase II Study of Adjuvant Use of Anti-Epidermal Growth Factor Receptor EGFR-425 in High Grade Gliomas | NCT00589706 | Gliomas | MAb-425 | 18 Years - | Drexel University | |
| Assistance in Neurosurgery (ExtempoRMN) | NCT02272452 | Primary Brain T... Glioma | High-Resolution... | 18 Years - | University Hospital, Strasbourg, France | |
| MRS of Glioma Genomics | NCT05700071 | Glioma | MRI | 18 Years - | Institut National de la Santé Et de la Recherche Médicale, France | |
| A Ketogenic Diet as a Complementary Treatment on Patients With High-grade Gliomas and Brain Metastases | NCT05564949 | Brain Cancer | CKD | 18 Years - 80 Years | Attikon Hospital | |
| Phase I/II: Decitabine/Vaccine Therapy in Relapsed/Refractory Pediatric High Grade Gliomas/Medulloblastomas/CNS PNETs | NCT02332889 | Gliomas Medulloblastoma Neuroectodermal... | Vaccine (autolo... Decitabine and ... | 2 Years - 25 Years | University of Louisville | |
| Treatment of Recurrent Brain Tumors: Metabolic Manipulation Combined With Radiotherapy | NCT02149459 | Brain Neoplasms | Partial brain r... Metformin low carbohydrat... | 18 Years - | Sheba Medical Center | |
| Clinical Trial of the Use of the Nasal Spray of Patients With Recurrence of Glioblastoma | NCT03275558 | Recurrent Gliob... Gliosarcoma Anaplastic Glio... | Axitinib 1 MG Sunitinib 5 MG Pazopanib 5 MG | 18 Years - 80 Years | Center Trials & Treatment | |
| A Ketogenic Diet as a Complementary Treatment on Patients With High-grade Gliomas and Brain Metastases | NCT05564949 | Brain Cancer | CKD | 18 Years - 80 Years | Attikon Hospital | |
| ZOOMit-fMRI Identifies Motor Functional Cortex | NCT03091270 | Gliomas | 18 Years - 70 Years | Beijing Neurosurgical Institute |
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