Spots Global Cancer Trial Database for brain
Every month we try and update this database with for brain cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.
The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
| Study title | NCT ID | Conditions | Interventions | Eligibility | Organization | Link |
|---|---|---|---|---|---|---|
| RCT of the 4mm vs. the 8mm Collimator for GKR of Brain Micrometastases | NCT02220127 | Brain Micrometa... | GKR with a sing... GKR with a sing... | 18 Years - | University College, London | |
| PET Imaging of Patients With Melanoma and Malignant Brain Tumors Using an 124I-labeled cRGDY Silica Nanomolecular Particle Tracer: A Microdosing Study | NCT01266096 | Newly Diagnosed... Malignant Brain... | PET scan with 1... | 18 Years - | Memorial Sloan Kettering Cancer Center | |
| Repeated Super-selective Intraarterial Cerebral Infusion of Bevacizumab (Avastin) for Treatment of Relapsed GBM and AA | NCT01269853 | Glioblastoma Mu... Anaplastic Astr... | Bevacizumab Bevacizumab | 18 Years - | Northwell Health | |
| Integrated Discovery of New Immuno-Molecular Actionable Biomarkers for Tumors With Immune-suppressed Environment | NCT03706625 | Non Hodgkin Lym... Non Small Cell ... Glioma | 18 Years - | Assistance Publique - Hôpitaux de Paris | ||
| Analysis of Brain Metastasis in Patients With Lung Cancer | NCT00071344 | Carcinoma, Non-... | - | National Institutes of Health Clinical Center (CC) | ||
| Phenylbutyrate to Treat Children With Progressive or Recurrent Brain Tumors | NCT00006450 | Brain Tumor | Phenylbutyrate | - | National Institutes of Health Clinical Center (CC) | |
| Hypofractionated Stereotactic Radiotherapy With Bevacizumab in the Treatment of Recurrent Malignant Glioma | NCT01392209 | Brain Cancer MALIGNANT GLIOM... Glioblastoma Anaplastic Astr... Anaplastic Olig... Anaplastic Olig... Anaplastic Mixe... Malignant Gliom... | Bevacizumab & S... | 18 Years - | Memorial Sloan Kettering Cancer Center | |
| Stereotactic Radiosurgery (SRS) for Multiple CNS Mets | NCT02567643 | Metastatic Canc... Brain Metastase... | Stereotactic Ra... | - | The Cooper Health System | |
| Fractionated Stereotactic Radiotherapy (FSRT) in Treatment of Brain Metastases | NCT02187822 | Brain Metastase... Generalized Mal... Brain Lesions | TPI 287 Fractionated St... | 18 Years - | H. Lee Moffitt Cancer Center and Research Institute | |
| Natural History of Patients With Brain and Spinal Cord Tumors | NCT00009035 | Astrocytoma Oligodendroglio... Glioblastoma Glioma Anaplastic Glio... | 1 Year - 100 Years | National Institutes of Health Clinical Center (CC) | ||
| Study of 4-Demethyl-4-cholesteryloxycarbonylpenclome (DM-CHOC-PEN) in Patients With Brain Tumors | NCT02038218 | Primary Brain T... Metastatic Mali... | 4-Demethyl-4-ch... | 18 Years - | DEKK-TEC, Inc. | |
| Safety of IMRT Treatment With Inhomogeneous Dose in Patients With Relapsed High-grade Gliomas. | NCT04610229 | Glioblastoma Mu... Glioblastoma Glioblastoma, A... | Hypofractionati... | 18 Years - | Arcispedale Santa Maria Nuova-IRCCS | |
| Multiple Dose Study of MPC-6827 in Subjects With Refractory Brain Metastases | NCT00393965 | Brain Neoplasms | MPC-6827 | 18 Years - | Myrexis Inc. | |
| Dose Escalation Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of QBS10072S | NCT04430842 | Astrocytoma Brain Cancer Brain Metastase... Bladder Cancer Breast Cancer Cervical Cancer Cholangiocarcin... Colorectal Canc... Esophagus Cance... Gastric Cancer Head and Neck C... Kidney Cancer Liver Cancer Lung Cancer Melanoma Ovarian Cancer Pancreatic Canc... Pleural Mesothe... Prostate Cancer Sarcoma Tongue Cancer Thymic Carcinom... Urinary Tract C... | QBS10072S | 18 Years - | Quadriga Biosciences, Inc. | |
| A Study to Evaluate Safety and Efficacy of ACT001 and Anti-PD-1 in Patients With Surgically Accessible Recurrent Glioblastoma Multiforme | NCT05053880 | Recurrent Gliob... | ACT001 ACT001 + Pembro... | 18 Years - | Accendatech USA Inc. | |
| Feasibility and Clinically Application of Magnetic Resonance Fingerprinting | NCT02387840 | Neurofibromatos... Brain Tumor Glioma | Magnetic Resona... Magnetic Resona... | - 35 Years | Case Comprehensive Cancer Center | |
| Heuristics, Algorithms and Machine Learning: Evaluation & Testing in Radiation Therapy | NCT04060706 | Cancer | Radical Image-G... | 18 Years - | Cambridge University Hospitals NHS Foundation Trust | |
| Stereotactic Radiosurgery (SRS) for Multiple CNS Mets | NCT02567643 | Metastatic Canc... Brain Metastase... | Stereotactic Ra... | - | The Cooper Health System | |
| Eligibility Screening of Patients With Central Nervous System Tumors for the National Cancer Institute s (NCI) Clinical Research Protocols | NCT00035373 | Glioblatoma Gliosarcoma Anaplastic Astr... Oligodendroglio... Anaplastic Olig... | 18 Years - 100 Years | National Institutes of Health Clinical Center (CC) | ||
| Refining and Testing the Electronic Social Network Assessment Program (eSNAP) | NCT03026699 | Brain Cancer | eSNAP Questionnaires | 18 Years - | H. Lee Moffitt Cancer Center and Research Institute | |
| A Study to Evaluate Safety and Efficacy of ACT001 and Anti-PD-1 in Patients With Surgically Accessible Recurrent Glioblastoma Multiforme | NCT05053880 | Recurrent Gliob... | ACT001 ACT001 + Pembro... | 18 Years - | Accendatech USA Inc. | |
| A Phase II Safety and Tolerability Study of Bevacizumab When Added to Single-agent Chemotherapy to Treat Patient With Breast Cancer Metastatic to Brain | NCT00476827 | Breast Cancer | Bevacizumab Docetaxel CPT-11 Paclitaxel Vinorelbine Tar... Gemcitabine | 18 Years - | Duke University | |
| Whole Brain Radiation Therapy With Oxygen, With or Without RSR13, in Women With Brain Metastases From Breast Cancer | NCT00083304 | Breast Cancer Metastases | Efaproxiral Whole Brain Rad... Supplemental Ox... | 18 Years - | Spectrum Pharmaceuticals, Inc | |
| Study of NovoTTF-200A Alone and With Temozolomide in Patients With Low-Grade Gliomas | NCT02507232 | Glioma | NovoTTF-200A Temozolomide | 18 Years - | Saint John's Cancer Institute | |
| Dexanabinol in Patients With Brain Cancer | NCT01654497 | Brain Cancer | Dexanabinol | 18 Years - | University of California, San Diego | |
| Acetyl-Amantadine as a Biomarker in Patients With Glioblastoma | NCT04530006 | Glioblastoma Mu... | Amantadine Hydr... | 18 Years - | CancerCare Manitoba | |
| Assess Use of 18F-Fluciclovine for Patients With Large Brain Metastases Treated With Staged Stereotactic Radiosurgery | NCT04689048 | Brain Metastase... Brain Metastase... Brain Cancer | 18F fluciclovin... | 18 Years - | Baptist Health South Florida | |
| RCT for Intermittent Versus Continuous Propofol Sedation for Pediatric Brain and Spine MRI Studies | NCT00515359 | Encephalopathy Developmental D... Cord Tumor Comp... Cord Tethering ... | Intermittent Pr... Continuous Prop... | 1 Month - 18 Years | Spectrum Health Hospitals | |
| Buparlisib in Melanoma Patients Suffering From Brain Metastases (BUMPER) | NCT02452294 | Malignant Melan... Metastases | Buparlisib | 18 Years - | University Hospital Tuebingen | |
| Phase I / II Vorinostat, Erlotinib and Temozolomide for Recurrent Glioblastoma Multiforme (GBM) | NCT01110876 | Brain Cancer Glioblastoma Mu... | Vorinostat Erlotinib Temozolomide | 18 Years - | M.D. Anderson Cancer Center | |
| Super-Selective Intraarterial Intracranial Infusion of Avastin (Bevacizumab) | NCT00968240 | Glioblastoma Mu... Anaplastic Astr... | Super-Selective... | 18 Years - | Northwell Health | |
| High-density EEG in Neurological Disorders | NCT04266041 | Epilepsy Tumor Healthy | High-density el... | 18 Years - | Dartmouth-Hitchcock Medical Center | |
| Integrated Discovery of New Immuno-Molecular Actionable Biomarkers for Tumors With Immune-suppressed Environment | NCT03706625 | Non Hodgkin Lym... Non Small Cell ... Glioma | 18 Years - | Assistance Publique - Hôpitaux de Paris | ||
| A Study to Evaluate Safety and Efficacy of ACT001 and Anti-PD-1 in Patients With Surgically Accessible Recurrent Glioblastoma Multiforme | NCT05053880 | Recurrent Gliob... | ACT001 ACT001 + Pembro... | 18 Years - | Accendatech USA Inc. | |
| DNX-2401 (Formerly Known as Delta-24-RGD-4C) for Recurrent Malignant Gliomas | NCT00805376 | Brain Cancer Central Nervous... | DNX-2401 Tumor Removal | 18 Years - | DNAtrix, Inc. | |
| AZD7451 for Recurrent Gliomas | NCT01468324 | Glioblastoma Mu... | AZD7451 | 18 Years - 100 Years | National Institutes of Health Clinical Center (CC) | |
| A Family Study of Adults With Glioma | NCT00339352 | Glioma | 18 Years - 100 Years | National Institutes of Health Clinical Center (CC) | ||
| Selecting Patient-Specific Biologically Targeted Therapy for Pediatric Patients With Refractory Or Recurrent Brain Tumors | NCT02015728 | Recurrent Child... | Tumor biology t... Temozolomide Etoposide Sorafenib Everolimus Erlotinib Dasatinib | 1 Month - 30 Years | Seattle Children's Hospital | |
| Phase 1, Multiple Dose Study of MPC-6827 in Subjects With Refractory Solid Tumors | NCT00394446 | Refractory Soli... | MPC-6827 | 18 Years - | Myrexis Inc. | |
| Fractionated Stereotactic Radiotherapy (FSRT) in Treatment of Brain Metastases | NCT02187822 | Brain Metastase... Generalized Mal... Brain Lesions | TPI 287 Fractionated St... | 18 Years - | H. Lee Moffitt Cancer Center and Research Institute | |
| Evaluation of Anatomy, Clinical and Neuropsychological Long-term Sequelae of Patients Treated With Radiation Therapy for Brain Tumor | NCT02791360 | Brain Neoplasms | Brain MRI | 18 Years - | Centre Francois Baclesse | |
| Whole Brain Radiation Therapy With Oxygen, With or Without RSR13, in Women With Brain Metastases From Breast Cancer | NCT00083304 | Breast Cancer Metastases | Efaproxiral Whole Brain Rad... Supplemental Ox... | 18 Years - | Spectrum Pharmaceuticals, Inc | |
| Phase I Human Analytics (HALO) Study | NCT05423860 | Cardiovascular ... Cancer Dementia Traumatic Brain... | no intervention... | 45 Years - 90 Years | HALO Diagnostics | |
| Phase II Study of SOM230 in Patients With Recurrent or Progressive Meningioma | NCT00813592 | Cancer | SOM230B | 18 Years - | University of Utah | |
| DNX-2401 With Interferon Gamma (IFN-γ) for Recurrent Glioblastoma or Gliosarcoma Brain Tumors | NCT02197169 | Glioblastoma or... | Single intratum... Interferon-gamm... | 18 Years - | DNAtrix, Inc. | |
| Phase I Trial of Stereotactic Radiosurgery Following Surgical Resection of Brain Metastases | NCT01395407 | Brain Metastasi... Neoplasm | Radiosurgery do... | 18 Years - | Emory University | |
| Humanized 3F8 Monoclonal Antibody (Hu3F8) in Patients With High-Risk Neuroblastoma and GD2-Positive Tumors | NCT01419834 | Neuroblastoma | Humanized 3F8 M... | 2 Years - | Memorial Sloan Kettering Cancer Center | |
| Study to Evaluate Safety, Tolerability, and Optimal Dose of Candidate GBM Vaccine VBI-1901 in Recurrent GBM Subjects | NCT03382977 | Glioblastoma Mu... | VBI-1901 Carmustine Lomustine | 18 Years - | VBI Vaccines Inc. | |
| Supplementation of L-arginine in Patients With Non-resectable Brain Metastases | NCT02844387 | Unresectable Mu... | L-arginine hydr... Placebo | 18 Years - | Instituto de Oncología Ángel H. Roffo | |
| Stereotactic Radiosurgery (SRS) for Multiple CNS Mets | NCT02567643 | Metastatic Canc... Brain Metastase... | Stereotactic Ra... | - | The Cooper Health System | |
| Study of Resection Combined With Stereotactic Radiosurgery for 1 to 3 Brain Metastases | NCT00904553 | Neoplasm Metast... | Novalis Shaped ... | 18 Years - | University of Rochester | |
| Study of 4-Demethyl-4-cholesteryloxycarbonylpenclome (DM-CHOC-PEN) in Patients With Brain Tumors | NCT02038218 | Primary Brain T... Metastatic Mali... | 4-Demethyl-4-ch... | 18 Years - | DEKK-TEC, Inc. | |
| Magnetic Resonance Imaging-Guided Laser Induced Thermal Therapy for Treatment of Metastatic Brain Tumors | NCT00787982 | Brain Neoplasms | MRI-Guided Lase... | - | Visualase, Inc. | |
| Imaging Brain Tumors With FACBC and Methionine | NCT00597246 | Brain Cancer CNS Cancer | FACBC, Methioni... PET Scan | - | Memorial Sloan Kettering Cancer Center | |
| Super-Selective Intraarterial Intracranial Infusion of Avastin (Bevacizumab) | NCT00968240 | Glioblastoma Mu... Anaplastic Astr... | Super-Selective... | 18 Years - | Northwell Health | |
| Neuropsychological Changes in Patients Receiving Radiation Therapy for Brain Metastases | NCT01445483 | Brain Metastasi... Cancer | 18 Years - | National Institutes of Health Clinical Center (CC) | ||
| Imaging Brain Tumors With FACBC and Methionine | NCT00597246 | Brain Cancer CNS Cancer | FACBC, Methioni... PET Scan | - | Memorial Sloan Kettering Cancer Center | |
| Super-Selective Intraarterial Cerebral Infusion Of Temozolomide (Temodar) For Treatment Of Newly Diagnosed GBM And AA | NCT01180816 | Glioblastoma Mu... Anaplastic Astr... | Super-Selective... | 18 Years - | Northwell Health | |
| Refining and Testing the Electronic Social Network Assessment Program (eSNAP) | NCT03026699 | Brain Cancer | eSNAP Questionnaires | 18 Years - | H. Lee Moffitt Cancer Center and Research Institute | |
| ZD6474 to Treat Advanced Brain Cancer in Patients | NCT00272350 | Recurrent High-... Progressive Low... Malignant Gliom... | Steroids ZD6474 | 18 Years - | National Institutes of Health Clinical Center (CC) | |
| Selecting Patient-Specific Biologically Targeted Therapy for Pediatric Patients With Refractory Or Recurrent Brain Tumors | NCT02015728 | Recurrent Child... | Tumor biology t... Temozolomide Etoposide Sorafenib Everolimus Erlotinib Dasatinib | 1 Month - 30 Years | Seattle Children's Hospital | |
| Advanced MRI Sequences for Radiation Therapy Treatment Planning | NCT02340715 | Cancer | 18 Years - 89 Years | Medical College of Wisconsin | ||
| Analysis of Brain Metastasis in Patients With Lung Cancer | NCT00071344 | Carcinoma, Non-... | - | National Institutes of Health Clinical Center (CC) | ||
| Whole Brain Radiation Therapy With Oxygen, With or Without RSR13, in Women With Brain Metastases From Breast Cancer | NCT00083304 | Breast Cancer Metastases | Efaproxiral Whole Brain Rad... Supplemental Ox... | 18 Years - | Spectrum Pharmaceuticals, Inc | |
| Intraoperative Functional Ultrasound | NCT02656407 | Brain Tumor Brain Lesion | Ultrasound devi... | 18 Years - | Institut National de la Santé Et de la Recherche Médicale, France | |
| AZD8055 for Adults With Recurrent Gliomas | NCT01316809 | Glioblastoma Mu... Anaplastic Astr... Anaplastic Olig... Malignant Gliom... Brainstem Gliom... | AZD8055 | 18 Years - 99 Years | National Institutes of Health Clinical Center (CC) | |
| 18-F-Fluoroacetate as PET Imaging Agent | NCT01320787 | Brain Cancer Breast Cancer Prostate Cancer | 18F-fluoroaceta... | 18 Years - | M.D. Anderson Cancer Center | |
| Acetyl-Amantadine as a Biomarker in Patients With Glioblastoma | NCT04530006 | Glioblastoma Mu... | Amantadine Hydr... | 18 Years - | CancerCare Manitoba | |
| Personalized Risk-Adapted Therapy in Post-Pubertal Patients With Newly-Diagnosed Medulloblastoma | NCT04402073 | Medulloblastoma | Sonidegib Cisplatin Lomustine Vincristine radiotherapy | 15 Years - | European Organisation for Research and Treatment of Cancer - EORTC | |
| Analysis of Brain Metastasis in Patients With Breast Cancer, With and Without Over-Expression of HER-2 | NCT00071383 | Breast Neoplasm... | - | National Institutes of Health Clinical Center (CC) | ||
| HLA-A2-Restricted Glioma Antigen-Peptides Vaccinations With Poly-ICLC for Recurrent WHO Grade II Gliomas | NCT00874861 | Astrocytoma Oligoastrocytom... Oligodendroglio... | Peptide vaccine... | 18 Years - | University of Pittsburgh | |
| GammaTile and Stupp in Newly Diagnosed GBM | NCT05342883 | Glioblastoma | Surgical tumor ... | 18 Years - | GT Medical Technologies, Inc. | |
| A Study Evaluating the Safety and Efficacy of ENV-101 (Taladegib) in Patients With Advanced Solid Tumors Harboring PTCH1 Loss of Function Mutations | NCT05199584 | Solid Tumors Wi... | ENV-101 (talade... | 18 Years - | Endeavor Biomedicines, Inc. | |
| Evaluation for NCI Radiation Oncology Branch Clinical Research Protocols | NCT00026689 | Prostate Brain Breast Lung Endometrial | - 90 Years | National Institutes of Health Clinical Center (CC) | ||
| Imaging Brain Tumors With FACBC and Methionine | NCT00597246 | Brain Cancer CNS Cancer | FACBC, Methioni... PET Scan | - | Memorial Sloan Kettering Cancer Center | |
| Enzastaurin to Treat Recurrent Brain Tumor | NCT00108056 | Glioma | Enzastaurin (LY... | 18 Years - | National Institutes of Health Clinical Center (CC) | |
| Repeated Super-selective Intraarterial Cerebral Infusion Of Bevacizumab Plus Carboplatin For Treatment Of Relapsed/Refractory GBM And Anaplastic Astrocytoma | NCT01386710 | Glioblastoma Mu... Anaplastic Astr... | Bevacizumab and... Bevacizumab and... | 18 Years - | Northwell Health | |
| Super-Selective Intraarterial Intracranial Infusion of Avastin (Bevacizumab) | NCT00968240 | Glioblastoma Mu... Anaplastic Astr... | Super-Selective... | 18 Years - | Northwell Health | |
| Molecular Imaging of Brain Tumors Using Labeled Technetium-99m 1-Thio-D-Glucose. | NCT04288518 | Brain Neoplasms | SPECT or SPECT-... | 18 Years - 70 Years | Tomsk National Research Medical Center of the Russian Academy of Sciences | |
| Valproate and Etoposide for Patients With Neuronal Tumors and Brain Metastases | NCT00513162 | Neuroectodermal... Brain Metastase... Advanced Cancer | Valproate Etoposide | - | M.D. Anderson Cancer Center |
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