Spots Global Cancer Trial Database for microbiome
Every month we try and update this database with for microbiome cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.
The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
| Study title | NCT ID | Conditions | Interventions | Eligibility | Organization | Link |
|---|---|---|---|---|---|---|
| Effects of the Use of Probiotics on the Intestinal Microbiota of Patients With Gastric Cancer | NCT06250075 | Gastric Adenoca... Gastric Cancer Microbiome Cytokines Nutritional Sta... | Formulation wit... Non-interventio... | 18 Years - | Universidade Federal do Amazonas | |
| Gut Microbiome and Treatment for Gynecological Cancer Patients Receiving Immunotherapy | NCT04957511 | Gynecologic Can... Immunotherapy Gut Microbiome | 18 Years - | Viome | ||
| Study To Evaluate The Safety And Efficacy of PBCLN-010 In Combination With PBCLN-014 in Participants Receiving Allogeneic Hematopoietic Cell Transplantation | NCT06102213 | Hematologic Mal... | B. infantis (PB... | 18 Years - 75 Years | Prolacta Bioscience | |
| Analyzing the Urine During BCG Instillation in Bladder Cancer Patients for Disease Followup | NCT06153849 | Bladder Cancer | urine sample co... | 18 Years - 99 Years | Changhai Hospital | |
| Utilization of Microbiome as Biomarkers and Therapeutics in Immuno-Oncology | NCT04264975 | Solid Carcinoma | fecal microbiot... | 19 Years - | Asan Medical Center | |
| Gut and Intratumoral Microbiome Effect on the Neoadjuvant Chemotherapy-induced Immunosurveillance in Triple Negative Breast Cancer | NCT03586297 | Triple Negative... | 18 Years - | Hackensack Meridian Health | ||
| Gut Microbiome Modification Through Dietary Intervention in Patients With Colorectal Cancer: Response to Surgery | NCT04869956 | Colorectal Canc... | Dietary pattern... Dietary pattern... | 18 Years - 80 Years | Fundacion para la Formacion e Investigacion Sanitarias de la Region de Murcia | |
| Polish Microbiome Map | NCT04169867 | Melanoma Healthy Volunte... Microbiome Metagenome Immunotherapy | Collection of s... | 18 Years - | Ardigen | |
| Walnuts and Colon Health | NCT05195970 | Colorectal Canc... Diet Habit | Walnuts | 39 Years - 75 Years | UConn Health | |
| Exercise, Gut Microbiome, and Breast Cancer: Increasing Reach to Underserved Populations | NCT05000502 | Female Breast C... | Home-based exer... | 18 Years - 70 Years | University of Alabama at Birmingham | |
| Melanoma Checkpoint and Gut Microbiome Alteration With Microbiome Intervention | NCT03817125 | Metastatic Mela... | Placebo for ant... Vancomycin pret... Nivolumab Matching Placeb... SER-401 | 18 Years - | Parker Institute for Cancer Immunotherapy | |
| Denver Garden Environment and Microbiome Study Disease | NCT03089151 | Diet Modificati... Physical Activi... Weight Gain Chronic Disease Lifestyle, Sede... Health Behavior | Community Garde... | 18 Years - | University of Colorado, Boulder | |
| Study To Evaluate The Safety And Efficacy of PBCLN-010 In Combination With PBCLN-014 in Participants Receiving Allogeneic Hematopoietic Cell Transplantation | NCT06102213 | Hematologic Mal... | B. infantis (PB... | 18 Years - 75 Years | Prolacta Bioscience | |
| Immune Resistance Interrogation Study | NCT04243720 | Cancer Solid Tumor Metastatic Canc... Immune Resistan... | 18 Years - | University Health Network, Toronto | ||
| Investigating the Microbiome and Volatile Organic Compound Profile of Children With Neuroblastoma | NCT03545542 | Microbial Colon... Neuroblastoma Children, Only | Initial fecal m... Initial fecal v... Initial breath ... Microbiome unde... Fecal volatile ... Breath volatile... Final microbiom... Final fecal vol... Final breath vo... | 1 Month - 8 Years | Medical University of Graz | |
| Utilization of Microbiome as Biomarkers and Therapeutics in Immuno-Oncology | NCT04264975 | Solid Carcinoma | fecal microbiot... | 19 Years - | Asan Medical Center | |
| Prebiotic Effect of Eicosapentaenoic Acid Treatment for Colorectal Cancer Liver Metastases | NCT04682665 | Colon Cancer Li... | Icosapent Ethyl... Placebo | 18 Years - | University of Leeds | |
| Analyzing the Urine During BCG Instillation in Bladder Cancer Patients for Disease Followup | NCT06153849 | Bladder Cancer | urine sample co... | 18 Years - 99 Years | Changhai Hospital | |
| Pilot Observational Study Examining the Effect of Endocrine Therapy on Aging | NCT05700006 | Breast Neoplasm... Arthralgia Aging | Aromatase inhib... | 18 Years - | University of Michigan | |
| Modulation of the Gut Microbiome With Pembrolizumab Following Chemotherapy in Resectable Pancreatic Cancer | NCT05462496 | Pancreatic Canc... | Biopsy FOLFIRINOX Ciprofloxacin Metronidazole Pembrolizumab Surgical Resect... | 19 Years - | Icahn School of Medicine at Mount Sinai | |
| Predictors of Normal Tissue Response From the Microenvironment in Radiotherapy for Prostate and Head-and-neck Cancer | NCT03294122 | Prostate Cancer Head and Neck C... | External beam r... External beam r... | 18 Years - | Fondazione IRCCS Istituto Nazionale dei Tumori, Milano | |
| Microbiome in Cancer Patients With High Dose Chemotherapy With Stem Cell Transplantation | NCT04691284 | Hematologic Neo... | Blood, urine an... | 18 Years - | National Cancer Institute, Slovakia | |
| Utilization of Microbiome as Biomarkers and Therapeutics in Immuno-Oncology | NCT04264975 | Solid Carcinoma | fecal microbiot... | 19 Years - | Asan Medical Center | |
| Microbiome in Immunotherapy naïve NSCLC Patients Receiving PD-1/L1 Blockade (MIP_NSCLC) | NCT04636775 | NSCLC Stage IV NSCLC, Recurren... | Microbiome | 18 Years - | University of Kansas Medical Center | |
| Microbiome and Papillary Thyroid Microcarcinoma | NCT04376203 | Papillary Thyro... Microbiome | Thyroidectomy | - | University of Ioannina | |
| The Microenvironment in Barrett's Esophagus | NCT03060642 | Barrett Esophag... Esophageal Aden... | Tethered capsul... Electronic nose... | 18 Years - | Columbia University | |
| Early Detection of Treatment Failure in Metastatic Colorectal Cancer Patients | NCT05068531 | Colorectal Canc... | 18 Years - | Centre hospitalier de l'Université de Montréal (CHUM) | ||
| Probiotics in the Prevention of Hepatocellular Carcinoma in Cirrhosis | NCT03853928 | Microbiota Hepatocellular ... Cirrhosis | Probiotics | 18 Years - | Austral University, Argentina | |
| Prospective Evaluation of Diagnosis and Treatment of Patients With Autoimmune Cytopenias Including Autoimmune Hemolytic Anemia, Immune Thrombocytopenia, and Chronic Idiopathic/Autoimmune Neutropenia | NCT05931718 | Autoimmune Hemo... Immune Thromboc... Chronic Idiopat... Autoimmune Neut... Myelodysplastic... Cold Agglutinin... | cytokine essays NGS Fecal microbiom... Erythropoietin Luspatercept Thrombopoietin ... G-CSF | 18 Years - | Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico | |
| Correlation Between Complications After Pancreaticoduodenectomy and Microbiota | NCT04931069 | Pancreatic Canc... | Microbiota anal... | 18 Years - | University Hospital, Toulouse | |
| Investigating the Microbiome and Volatile Organic Compound Profile of Children With Neuroblastoma | NCT03545542 | Microbial Colon... Neuroblastoma Children, Only | Initial fecal m... Initial fecal v... Initial breath ... Microbiome unde... Fecal volatile ... Breath volatile... Final microbiom... Final fecal vol... Final breath vo... | 1 Month - 8 Years | Medical University of Graz | |
| Development and Analysis of a Stool Bank for Cancer Patients | NCT04291755 | Carcinoma, Non-... Carcinoma, Colo... | Pembrolizumab I... | 18 Years - | Persephone Biosciences | |
| Beans/Bran Enriching Nutritional Eating For Intestinal Health Trial | NCT01929122 | Colorectal Canc... | Placebo-Control... Cooked Navy Bea... Rice Bran Meals... | 18 Years - | Colorado State University | |
| Correlation Between Complications After Pancreaticoduodenectomy and Microbiota | NCT04931069 | Pancreatic Canc... | Microbiota anal... | 18 Years - | University Hospital, Toulouse | |
| Correlation of Fecal Microbiome and Its Metabolites With Outcome of Radiotherapy in Head and Neck Carcinoma | NCT05156177 | Head and Neck S... | 18 Years - | Institute of Oncology Ljubljana | ||
| Body Fat as Determinant of Female Gonadal Dysfunction | NCT03841981 | Polycystic Ovar... Hypothalamic Am... | Anthropometric ... Indirect calori... Biochemical, ho... Sonographic stu... 24-hour Ambulat... Percutaneous bi... Cardiovascular ... Oral smear and ... | 18 Years - 40 Years | Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal | |
| Reducing Metabolic Dysregulation in Dyads | NCT06117241 | Colorectal Canc... Inflammation Nutrition Relat... | IMAGINE HEALTHY | 9 Years - 55 Years | University of South Carolina | |
| Prospective Evaluation of Diagnosis and Treatment of Patients With Autoimmune Cytopenias Including Autoimmune Hemolytic Anemia, Immune Thrombocytopenia, and Chronic Idiopathic/Autoimmune Neutropenia | NCT05931718 | Autoimmune Hemo... Immune Thromboc... Chronic Idiopat... Autoimmune Neut... Myelodysplastic... Cold Agglutinin... | cytokine essays NGS Fecal microbiom... Erythropoietin Luspatercept Thrombopoietin ... G-CSF | 18 Years - | Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico | |
| Microbiome and Papillary Thyroid Microcarcinoma | NCT04376203 | Papillary Thyro... Microbiome | Thyroidectomy | - | University of Ioannina | |
| Phytoestrogens and Colonic Adenomatous Polyps | NCT03417258 | Intestinal Poly... | 50 Years - 75 Years | University of Bari | ||
| The Oronasal Microbiota in Pediatric Oncology Patients | NCT02949427 | Acute Myeloid L... Hematologic Mal... Bone Marrow Tra... | 4 Years - 21 Years | St. Jude Children's Research Hospital | ||
| Predictors of Normal Tissue Response From the Microenvironment in Radiotherapy for Prostate and Head-and-neck Cancer | NCT03294122 | Prostate Cancer Head and Neck C... | External beam r... External beam r... | 18 Years - | Fondazione IRCCS Istituto Nazionale dei Tumori, Milano | |
| Pro-Vegetarian Diets, Microbial/Metabolite Profiles and Cancer | NCT05621122 | Dietary Habits Food Habits Nutrition, Heal... Cancer Metabolic Disea... | This is an obse... | 18 Years - | Universidad de Granada | |
| Trial to Assess the Effects of an Antimicrobial Mouthwash on the Esophageal Microbiome | NCT02513784 | Esophageal Aden... Barrett's Esoph... Reflux Esophagi... | Chlorhexidine g... | 18 Years - | Columbia University | |
| Intestinal Microbiota in Prostate Cancer Patients as a Biomarker for Radiation-INduced Toxicity (IMPRINT) | NCT04638049 | Prostate Cancer Prostate Adenoc... Prostatic Neopl... | Collection of h... Patient reporte... | 18 Years - | University Hospital, Ghent | |
| Dissecting the Role of MIcrobioMe in gastroEsophageal Tumor: a multIdisCiplinary Longitudinal Study | NCT06405035 | Adenocarcinoma | 18 Years - | European Institute of Oncology | ||
| Evaluation of Gut Microbiome in Patients With Prostate Cancer | NCT03709485 | Prostate Cancer | rectal swab for... | 45 Years - | Ziv Hospital | |
| Phytoestrogens and Colonic Adenomatous Polyps | NCT03417258 | Intestinal Poly... | 50 Years - 75 Years | University of Bari | ||
| Vancomycin for C Difficile NAAT+/EIA- Hematology Oncology Patients | NCT03030248 | Clostridium Dif... Hematologic Dis... Bone Marrow Tra... Oncologic Disor... | Vancomycin Oral... Placebo Oral Ca... | 18 Years - | Medical College of Wisconsin | |
| Correlates of CRCI and Gut Microbiome Dysbiosis; a Pilot Study | NCT06098404 | Cancer | 18 Years - | The University of Texas Medical Branch, Galveston | ||
| Role of Microbiome in BCG Responsiveness Prediction | NCT05204199 | Microbiome Bladder Cancer | 18 Years - 90 Years | University of Zurich | ||
| ARGONAUT: Stool and Blood Sample Bank for Cancer Patients | NCT04638751 | Non-small Cell ... Colorectal Canc... Triple Negative... Pancreas Cancer | Immunotherapy Chemotherapy CRC surgical re... Colonoscopy | 18 Years - | Persephone Biosciences | |
| Metabiomics Colon Cancer Clinical Research Study | NCT02151123 | Colonic Neoplas... | 18 Years - 95 Years | Metabiomics Corp | ||
| Avera Cancer Sequencing and Analytics Protocol (ASAP) | NCT05142033 | Cancer Cancer Diagnosi... Early Detection... Breast Cancer Lung Cancer Colon Cancer GI Cancer Gynecologic Can... Ovarian Cancer Endometrial Can... CNS Cancer Hematologic Can... | 18 Years - | Avera McKennan Hospital & University Health Center | ||
| Intestinal Microbiota in Prostate Cancer Patients as a Biomarker for Radiation-INduced Toxicity (IMPRINT) | NCT04638049 | Prostate Cancer Prostate Adenoc... Prostatic Neopl... | Collection of h... Patient reporte... | 18 Years - | University Hospital, Ghent | |
| Gut Microbiome Components Predict Response to Neoadjuvant Therapy in HER2-positive Breast Cancer Patients : A Prospective Study | NCT05444647 | Breast Cancer | stool and blood... | 18 Years - 70 Years | The First Affiliated Hospital with Nanjing Medical University | |
| A Non-Interventional Pilot Study to Explore the Skin Microbes in Skin Cancer | NCT04099446 | Skin Cancer Melanoma (Skin) Squamous Cell C... Basal Cell Carc... Microbiome | Non-interventio... | 18 Years - | ProgenaBiome | |
| Beans/Bran Enriching Nutritional Eating For Intestinal Health Trial | NCT01929122 | Colorectal Canc... | Placebo-Control... Cooked Navy Bea... Rice Bran Meals... | 18 Years - | Colorado State University | |
| Predictors of Normal Tissue Response From the Microenvironment in Radiotherapy for Prostate and Head-and-neck Cancer | NCT03294122 | Prostate Cancer Head and Neck C... | External beam r... External beam r... | 18 Years - | Fondazione IRCCS Istituto Nazionale dei Tumori, Milano | |
| Safety and Potential Efficacy of MS-20 In Combination With Pembrolizumab for the Treatment of NSCLC | NCT04909034 | NSCLC Stage IV | MS-20 Placebo | 20 Years - | Microbio Co Ltd | |
| BioForte Technology for in Silico Identification of Candidates for a New Microbiome-based Therapeutics and Diagnostics | NCT04136470 | Non Small Cell ... Microbiome Metagenome Immunotherapy Melanoma | Collection of s... | 18 Years - | Ardigen | |
| Prebiotics in Rectal Cancer | NCT05516641 | Rectal Cancer | Soluble Corn Fi... Maltodextrin | 18 Years - | Ochsner Health System | |
| Impact of HPV on a Cohort of Southern Italian Women: Epidemiological, Clinical, Morphological and Microbiological Features | NCT03959410 | Cervix Cancer | Cervical biopsy | 18 Years - 50 Years | University of Campania "Luigi Vanvitelli" | |
| Pro-Vegetarian Diets, Microbial/Metabolite Profiles and Cancer | NCT05621122 | Dietary Habits Food Habits Nutrition, Heal... Cancer Metabolic Disea... | This is an obse... | 18 Years - | Universidad de Granada | |
| Skin Barrier and Microbiome of CTCL Patients | NCT05827107 | Lymphoma, T-Cel... | 18 Years - | Centre for Human Drug Research, Netherlands | ||
| A First-in-human (FIH) Combination Treatment Study With a Single Dose Level of BMC128 | NCT05354102 | Non-small Cell ... Melanoma Renal Cell Carc... | BMC128 Nivolumab | 18 Years - | Biomica Ltd. | |
| The Microbiome of Oesophageal Squamous Cell Carcinoma | NCT04425122 | Esophageal Canc... Microbial Colon... | Upper endoscopy Upper endoscopy | 18 Years - | Chinese University of Hong Kong | |
| Tumor Immunotherapy and Microbiome Analysis | NCT04579978 | Advanced Solid ... | 18 Years - | Sunnybrook Health Sciences Centre | ||
| Melanoma Checkpoint and Gut Microbiome Alteration With Microbiome Intervention | NCT03817125 | Metastatic Mela... | Placebo for ant... Vancomycin pret... Nivolumab Matching Placeb... SER-401 | 18 Years - | Parker Institute for Cancer Immunotherapy | |
| Dissecting the Role of MIcrobioMe in gastroEsophageal Tumor: a multIdisCiplinary Longitudinal Study | NCT06405035 | Adenocarcinoma | 18 Years - | European Institute of Oncology | ||
| Low-Carb Versus Mediterranean Diet in PCOS | NCT05272657 | Polycystic Ovar... | low-carbohydrat... Mediterranean d... | 18 Years - 44 Years | Federal State Budgetary Institution, V. A. Almazov Federal North-West Medical Research Centre, of the Ministry of Health | |
| Evaluating the Bacterial and Fungal Microbiome in Patients With Calcium Oxalate Urolithiasis and Renal Cell Carcinoma | NCT04669860 | Calcium Oxalate... Renal Cell Carc... | 18 Years - | University of Miami | ||
| Pilot Observational Study Examining the Effect of Endocrine Therapy on Aging | NCT05700006 | Breast Neoplasm... Arthralgia Aging | Aromatase inhib... | 18 Years - | University of Michigan | |
| Trial to Assess the Effects of an Antimicrobial Mouthwash on the Esophageal Microbiome | NCT02513784 | Esophageal Aden... Barrett's Esoph... Reflux Esophagi... | Chlorhexidine g... | 18 Years - | Columbia University | |
| Akkermansia Muciniphilia and Metabolic Side Effects of ADT | NCT05802121 | Prostate Cancer Metabolic Syndr... Obesity Cardiovascular ... Bone Diseases Hyperlipidemias Diabetes | Apple Cider Vin... Placebo | 18 Years - | Western University | |
| The Microenvironment in Barrett's Esophagus | NCT03060642 | Barrett Esophag... Esophageal Aden... | Tethered capsul... Electronic nose... | 18 Years - | Columbia University | |
| Development and Analysis of a Stool Bank for Cancer Patients | NCT04291755 | Carcinoma, Non-... Carcinoma, Colo... | Pembrolizumab I... | 18 Years - | Persephone Biosciences | |
| Modulation of the Gut Microbiome With Pembrolizumab Following Chemotherapy in Resectable Pancreatic Cancer | NCT05462496 | Pancreatic Canc... | Biopsy FOLFIRINOX Ciprofloxacin Metronidazole Pembrolizumab Surgical Resect... | 19 Years - | Icahn School of Medicine at Mount Sinai | |
| Reducing Metabolic Dysregulation in Dyads | NCT06117241 | Colorectal Canc... Inflammation Nutrition Relat... | IMAGINE HEALTHY | 9 Years - 55 Years | University of South Carolina | |
| Combination Study of Antibiotics With Enzalutamide (PROMIZE) | NCT06126731 | Metastatic Cast... | Enzalutamide 40... Amoxicillin 500... Metronidazole 4... Vancomycin 125m... Ciprofloxacin 5... | 18 Years - | Institute of Cancer Research, United Kingdom |
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