Spots Global Cancer Trial Database for pediatrics
Every month we try and update this database with for pediatrics cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.
The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
Study title | NCT ID | Conditions | Interventions | Eligibility | Organization | Link |
---|---|---|---|---|---|---|
A Trial of Poly-ICLC in the Management of Recurrent Pediatric Low Grade Gliomas | NCT01188096 | Brain Tumors | Poly ICLC | - 21 Years | Wake Forest University Health Sciences | |
This is a Phase 1 Study of Eribulin Mesylate in Pediatric Participants With Recurrent or Refractory Solid Tumors (Excluding [Central Nervous System] CNS), Including Lymphomas | NCT02171260 | Pediatrics Solid Tumors | Eribulin Mesyla... | 6 Months - 17 Years | Eisai Inc. | |
A Phase II Trial of Intensity-Modulated Proton Therapy for Incompletely Resected Craniopharyngioma and Observation for Craniopharyngioma After Radical Resection | NCT02792582 | Craniopharyngio... | Proton Therapy Surgery | - 21 Years | St. Jude Children's Research Hospital | |
The Neuro-protective Effects of Exercise in Children With Brain Tumors | NCT01944761 | Brain Tumor | Exercise Progra... | 7 Years - 17 Years | The Hospital for Sick Children | |
Safety and Feasibility of Intraoperative Visualization With Cytalux in Children | NCT06235125 | Osteosarcoma Pulmonary Metas... Fluorescence Metastatic Sarc... Pediatrics | Cytalux | 6 Years - 17 Years | Ann & Robert H Lurie Children's Hospital of Chicago | |
Durvalumab in Pediatric and Adolescent Patients | NCT02793466 | Solid Tumor Lymphoma Central Nervous... | Durvalumab; MED... | 1 Year - 17 Years | Children's Hospital Los Angeles | |
Real World Evidence on the Use of Medical Cannabis in Pediatrics | NCT05863910 | Cancer Epilepsy Neurodevelopmen... | Medical Cannabi... | 3 Years - 17 Years | University of Manitoba | |
Children's Resiliency, Adjustment, and Coping | NCT00489632 | Leukemia | Questionnaire | 6 Years - 18 Years | M.D. Anderson Cancer Center | |
CANnabinoids in Pediatric ONCology | NCT05754840 | Childhood Cance... Cancer | MPL-001 MPL-005 MPL-009 | 4 Years - 18 Years | University of Manitoba | |
Haploidentical Natural Killer (NK) Cells With Epratuzumab for Relapsed Acute Lymphoblastic Leukemia (ALL) | NCT00941928 | Leukemia Pediatric Cance... | Epratuzumab Fludarabine Cyclophosphamid... Mesna Infusion of NK ... Interleukin-2 | - | M.D. Anderson Cancer Center | |
Household Air Pollution and Health: A Multi-country LPG Intervention Trial | NCT02944682 | Infant, Low Bir... | Liquefied petro... | 18 Years - 79 Years | Emory University | |
Losartan + Sunitinib in Treatment of Osteosarcoma | NCT03900793 | Osteosarcoma | Losartan Sunitinib | 10 Years - 40 Years | University of Colorado, Denver | |
Study of SBRT Efficacy on Intra and Extra -Cranial Tumors or Metastasis in Pediatrics Population (SBRT Pediatrics) | NCT02013297 | Brain Metastasi... Spinal Tumors Lung Tumors Ependymoma | SBRT treatment | 18 Months - 20 Years | Centre Leon Berard | |
Study of Efficacy and Safety of Dabrafenib in Combination With Trametinib in Pediatric Patients With BRAF V600 Mutation Positive LGG or Relapsed or Refractory HGG Tumors | NCT02684058 | Diffuse Astrocy... Anaplastic Astr... Astrocytoma Oligodendroglio... Anaplastic Olig... Glioblastoma Pilocytic Astro... Giant Cell Astr... Pleomorphic Xan... Anaplastic Pleo... Angiocentric Gl... Chordoid Glioma... Gangliocytoma Ganglioglioma Anaplastic Gang... Dysplastic Gang... Desmoplastic In... Papillary Glion... Rosette-forming... Central Neurocy... Extraventricula... Cerebellar Ipon... | Dabrafenib trametinib Carboplatin Vincristine | 12 Months - 17 Years | Novartis | |
A Study to Compare the Efficacy and Safety of Ifosfamide and Etoposide With or Without Lenvatinib in Children, Adolescents and Young Adults With Relapsed and Refractory Osteosarcoma | NCT04154189 | Osteosarcoma | Lenvatinib Ifosfamide Etoposide Lenvatinib | 2 Years - 25 Years | Eisai Inc. | |
CANnabinoids in Pediatric ONCology | NCT05754840 | Childhood Cance... Cancer | MPL-001 MPL-005 MPL-009 | 4 Years - 18 Years | University of Manitoba | |
Intercontinental Multidisciplinary Registry and Treatment Optimization Study for Choroid Plexus Tumors | NCT01014767 | Brain Cancer Choroid Plexus ... | Carboplatin Cisplatin Cyclophosphamid... Dactinomycin Doxorubicin Etoposide Irinotecan Leucovorin Methotrexate Temozolomide Vincristine | - | Tufts Medical Center | |
the Efficacy and Safety of Sugammadex in Children 0-2 Years Old | NCT03728543 | Anesthesia Pediatric Cance... Pediatric Tumor Pediatric Hepat... Beta-Thalassemi... Hepatic Metasta... | Sugammadex | - 18 Years | Federal Research Institute of Pediatric Hematology, Oncology and Immunology | |
Identifying, Understanding, and Overcoming Barriers to the Use of Clinical Practice Guidelines in Pediatric Oncology | NCT02847130 | Acute Lymphobla... B-Cell Non-Hodg... Childhood Acute... Childhood Burki... Childhood Neopl... Hematopoietic a... Malignant Solid... Recurrent Child... | Informational I... Interview Medical Chart R... Questionnaire A... | - 20 Years | Children's Oncology Group | |
COVID-19 in Immunosuppressed Children | NCT04511429 | Infections, Cor... Kidney Transpla... Liver Transplan... Cancer Covid19 | 1 Month - 18 Years | D'Or Institute for Research and Education | ||
Children's Resiliency, Adjustment, and Coping | NCT00489632 | Leukemia | Questionnaire | 6 Years - 18 Years | M.D. Anderson Cancer Center | |
Pilot Study of Zoledronic Acid and Interleukin-2 for Refractory Pediatric Neuroblastoma | NCT01404702 | Neuroblastoma | Zoledronic Acid Aldesleukin | 2 Years - 21 Years | University of Alabama at Birmingham | |
SPOG 2015 FN Definition. A Multi-center Non-inferiority Trial on Safety of a High Versus Low Temperature Limit Defining Fever in Pediatric Patients With Cancer at Risk for Fever in Chemotherapy-induced Neutropenia | NCT02324231 | Cancer Pediatrics Fever Neutropenia Fever in Neutro... | 39.0°C temperat... 38.5°C temperat... | 1 Year - 18 Years | Swiss Pediatric Oncology Group | |
Pilot Study Combining Temozolomide, Oncovin, Camptosar and Oral Antibiotic in Children and Adolescents With Recurrent Malignancy | NCT00222443 | Lymphomas Tumors | Irinotecan | 1 Year - 21 Years | University of Oklahoma | |
Comparative Evaluation of MRI and MDCT for the Detection of Metastic Pulmonary Nodules | NCT00751920 | Metastatic Pulm... | Enhanced MRI Sc... | 2 Years - 18 Years | The Hospital for Sick Children | |
Pediatric Long-Term Follow-up and Rollover Study | NCT03975829 | Diffuse Astrocy... Anaplastic Astr... Astrocytoma Oligodendroglio... Anaplastic Olig... Glioblastoma Pilocytic Astro... Giant Cell Astr... Pleomorphic Xan... Anaplastic Pleo... Angiocentric Gl... Chordoid Glioma... Gangliocytoma Ganglioglioma Anaplastic Gang... Dysplastic Gang... Desmoplastic In... Papillary Glion... Rosette-forming... Central Neurocy... Extraventricula... Cerebellar Lipo... Neurofibromatos... | dabrafenib trametinib | 1 Year - | Novartis | |
Phase I/II Trial: Engineered Donor Graft (Orca Q) for Pediatric Hematopoietic Cell Transplant (HCT) | NCT05322850 | Acute Myeloid L... Acute Lymphoid ... Mixed Phenotype... Acute Undiffere... Chronic Myeloid... Chronic Myeloid... Chronic Myeloid... | Orca-Q | - 50 Years | University of Florida | |
COVID-19 in Immunosuppressed Children | NCT04511429 | Infections, Cor... Kidney Transpla... Liver Transplan... Cancer Covid19 | 1 Month - 18 Years | D'Or Institute for Research and Education | ||
Co-administration of Propofol and Remifentanil for Lumbar Puncture in Children | NCT00405522 | Spinal Puncture | Propofol 2.0 mg... Propofol 4.0 mg... | 3 Years - 12 Years | The Hospital for Sick Children | |
Bortezomib With Chemotherapy for Relapsed Pediatric Acute Lymphoblastic Leukemia (ALL) | NCT00440726 | Acute Lymphobla... | Bortezomib Dexamethasone PEG-asparaginas... Doxorubicin Cytarabine Methotrexate Vincristine Triple IT Thera... | 1 Year - 21 Years | Therapeutic Advances in Childhood Leukemia Consortium | |
Pediatric Long-Term Follow-up and Rollover Study | NCT03975829 | Diffuse Astrocy... Anaplastic Astr... Astrocytoma Oligodendroglio... Anaplastic Olig... Glioblastoma Pilocytic Astro... Giant Cell Astr... Pleomorphic Xan... Anaplastic Pleo... Angiocentric Gl... Chordoid Glioma... Gangliocytoma Ganglioglioma Anaplastic Gang... Dysplastic Gang... Desmoplastic In... Papillary Glion... Rosette-forming... Central Neurocy... Extraventricula... Cerebellar Lipo... Neurofibromatos... | dabrafenib trametinib | 1 Year - | Novartis | |
The Management of Postoperative Craniotomy Pain in Pediatric Patients | NCT01576601 | Post Craniotomy... Cancer Epilepsy Vascular Malfor... Craniofacial Re... | - 18 Years | Johns Hopkins University | ||
Proton Beam Radiation Therapy for Intraocular and Periocular Retinoblastoma | NCT00432445 | Retinoblastoma | Proton Beam Rad... Ophthalmic EUA | - | M.D. Anderson Cancer Center | |
FLT PET: A Pilot Study in Lymphoma Patients | NCT04028804 | Hodgkin's Lymph... Non-Hodgkin's L... | FDG PET FLT PET | 1 Day - 18 Years | The Hospital for Sick Children | |
The Management of Postoperative Craniotomy Pain in Pediatric Patients | NCT01576601 | Post Craniotomy... Cancer Epilepsy Vascular Malfor... Craniofacial Re... | - 18 Years | Johns Hopkins University | ||
Sirolimus in Combination With Metronomic Chemotherapy in Children With High-Risk Solid Tumors | NCT04469530 | Solid Tumor | Sirolimus Cyclophosphamid... Etoposide Celecoxib | 1 Year - 30 Years | Emory University | |
Phase 2 Study of Vinblastine in Children With Recurrent or Refractory Low Grade Glioma | NCT00213278 | Glioma | vinblastine sul... | 1 Day - 21 Years | The Hospital for Sick Children | |
Thiotepa-Clofarabine-Busulfan With Allogeneic Stem Cell Transplant for High Risk Malignancies | NCT00857389 | Stem Cell Trans... Leukemia Lymphoma | Thiotepa Clofarabine Busulfan Allogeneic Stem... Thymoglobulin (... G-CSF (Filgrast... Tacrolimus Methotrexate Cyclophosphamid... Mesna | - 60 Years | M.D. Anderson Cancer Center | |
Cord Blood Fucosylation to Enhance Homing and Engraftment in Patients With Hematologic Malignancies | NCT01471067 | Blood And Marro... Leukemia Lymphoma Transplantation... Transplantation... | Melphalan Fludarabine Mycophenolate m... Tacrolimus Cord Blood Infu... Rituximab ATG Busulfan Clofarabine Total Body Irra... | 1 Year - 80 Years | M.D. Anderson Cancer Center | |
The Use of 5-aminolevulinic Acid (ALA) as an Intraoperative Tumor Marker for Resection of Pediatric Central Nervous System (CNS) Tumors | NCT02050243 | Central Nervous... | 5ALA | 3 Years - 18 Years | Tel-Aviv Sourasky Medical Center | |
The Neuro-protective Effects of Exercise in Children With Brain Tumors | NCT01944761 | Brain Tumor | Exercise Progra... | 7 Years - 17 Years | The Hospital for Sick Children | |
FLT PET: A Pilot Study in Lymphoma Patients | NCT04028804 | Hodgkin's Lymph... Non-Hodgkin's L... | FDG PET FLT PET | 1 Day - 18 Years | The Hospital for Sick Children | |
Intercontinental Multidisciplinary Registry and Treatment Optimization Study for Choroid Plexus Tumors | NCT01014767 | Brain Cancer Choroid Plexus ... | Carboplatin Cisplatin Cyclophosphamid... Dactinomycin Doxorubicin Etoposide Irinotecan Leucovorin Methotrexate Temozolomide Vincristine | - | Tufts Medical Center | |
Study of Efficacy and Safety of Dabrafenib in Combination With Trametinib in Pediatric Patients With BRAF V600 Mutation Positive LGG or Relapsed or Refractory HGG Tumors | NCT02684058 | Diffuse Astrocy... Anaplastic Astr... Astrocytoma Oligodendroglio... Anaplastic Olig... Glioblastoma Pilocytic Astro... Giant Cell Astr... Pleomorphic Xan... Anaplastic Pleo... Angiocentric Gl... Chordoid Glioma... Gangliocytoma Ganglioglioma Anaplastic Gang... Dysplastic Gang... Desmoplastic In... Papillary Glion... Rosette-forming... Central Neurocy... Extraventricula... Cerebellar Ipon... | Dabrafenib trametinib Carboplatin Vincristine | 12 Months - 17 Years | Novartis | |
Fever and Neutropenia in Pediatric Oncology Patients | NCT03768869 | Fever Neutropenia | Low Risk: Oupat... Low Risk: Inpat... High Risk: Inpa... | 0 Years - 21 Years | University of Colorado, Denver | |
Study of BLZ-100 in Pediatric Subjects With CNS Tumors | NCT02462629 | Central Nervous... | BLZ-100 | 1 Month - 30 Years | Blaze Bioscience Inc. | |
3D Modeling of the Cervico-facial Region and Cranial Nerve Tractography: IMAG 2 ORL Project | NCT05763615 | Head and Neck N... Congenital Abno... | Tractography MR... | 1 Year - 5 Years | Assistance Publique - Hôpitaux de Paris | |
Infusion of Expanded Cord Blood T Cells | NCT00972101 | Stem Cell Trans... Leukemia Lymphoma Pediatric Disor... | Total Body Irra... Melphalan Thiotepa Fludarabine Rituximab Etoposide Anti-thymocyte ... Mycophenolate M... Tacrolimus Cord Blood Infu... G-CSF Ex vivo expande... | - 55 Years | M.D. Anderson Cancer Center | |
Community Central Line Infection Prevention Trial | NCT02351258 | Infection | 70% Isopropyl a... Usual Care | 1 Day - 35 Years | Johns Hopkins University | |
A Study to Evaluate Glofitamab Monotherapy and Glofitamab + Chemoimmunotherapy in Pediatric and Young Adult Participants With Relapsed/Refractory Mature B-Cell Non-Hodgkin Lymphoma | NCT05533775 | Mature B-Cell N... | Obinutuzumab Glofitamab Rituximab Ifosfamide Carboplatin Etoposide Tocilizumab | 6 Months - 30 Years | Hoffmann-La Roche | |
Intercontinental Multidisciplinary Registry and Treatment Optimization Study for Choroid Plexus Tumors | NCT01014767 | Brain Cancer Choroid Plexus ... | Carboplatin Cisplatin Cyclophosphamid... Dactinomycin Doxorubicin Etoposide Irinotecan Leucovorin Methotrexate Temozolomide Vincristine | - | Tufts Medical Center | |
A Trial of Poly-ICLC in the Management of Recurrent Pediatric Low Grade Gliomas | NCT01188096 | Brain Tumors | Poly ICLC | - 21 Years | Wake Forest University Health Sciences | |
Weekly Vinblastine for Chemotherapy Naive Children With Progressive Low Grade Glioma (PLGGs) | NCT00575796 | Glioma | Vinblastine Sul... | 1 Year - 18 Years | The Hospital for Sick Children | |
Collaborative Assessment of Pediatric Transverse Myelitis: Understand, Reveal, Educate or CAPTURE Study | NCT02144935 | Myelitis, Trans... Flaccid Paraple... Flaccid Paraple... | - 17 Years | University of Texas Southwestern Medical Center | ||
Irinotecan in Combination With Cisplatin in Pediatric Patients With Unfavorable Prognosis Gliomas | NCT01574092 | Pediatric High ... | Combination of ... | 6 Months - 18 Years | Hospital Sant Joan de Deu | |
Rituximab for Patients With Relapsed Acute Lymphoblastic Leukemia | NCT01230788 | Leukemia Acute Lymphobla... ALL | rituximab | 1 Year - 30 Years | Emory University | |
Weekly Vinblastine for Chemotherapy Naive Children With Progressive Low Grade Glioma (PLGGs) | NCT00575796 | Glioma | Vinblastine Sul... | 1 Year - 18 Years | The Hospital for Sick Children | |
Co-administration of Propofol and Remifentanil for Lumbar Puncture in Children | NCT00405522 | Spinal Puncture | Propofol 2.0 mg... Propofol 4.0 mg... | 3 Years - 12 Years | The Hospital for Sick Children | |
Allogeneic Stem Cell Transplantation for Children With CML | NCT02707393 | Chronic Myeloid... | Fludarabine Thiotepa Melphalan ATG Cyclosporine A Mycophenolate m... bone marrow or ... | 1 Year - 18 Years | St. Anna Kinderkrebsforschung | |
Dual Task Gait Performance in Pediatric Oncology Patients | NCT04784026 | Pediatric Cance... | Gait assessment... Dual task gait ... Dual tak gait a... | 6 Years - 18 Years | Afyonkarahisar Health Sciences University | |
Losartan + Sunitinib in Treatment of Osteosarcoma | NCT03900793 | Osteosarcoma | Losartan Sunitinib | 10 Years - 40 Years | University of Colorado, Denver | |
Taurolidine Lock Solution in the Prevention of Catheter Related Bacteremia | NCT00735813 | Bacteremia Neoplasms | Taurolock Heparin | - 17 Years | Aarhus University Hospital | |
FLT PET: A Pilot Study in Lymphoma Patients | NCT04028804 | Hodgkin's Lymph... Non-Hodgkin's L... | FDG PET FLT PET | 1 Day - 18 Years | The Hospital for Sick Children | |
Vaccine Responses to Influenza A H1N1/09 Immunization in High-risk Patients | NCT01022905 | HIV Infection Rheumatic Disea... Cancer Transplant Pediatrics | Adjuvanted infl... | 6 Months - | University Hospital, Geneva | |
The Use of 5-aminolevulinic Acid (ALA) as an Intraoperative Tumor Marker for Resection of Pediatric Central Nervous System (CNS) Tumors | NCT02050243 | Central Nervous... | 5ALA | 3 Years - 18 Years | Tel-Aviv Sourasky Medical Center | |
Blood Brain Barrier (BBB) Disruption Using Exablate Focused Ultrasound With Doxorubicin for Treatment of Pediatric DIPG | NCT05630209 | Brain Tumor | Exablate Doxorubicin | 5 Years - 21 Years | InSightec | |
Phase I/II Trial: Engineered Donor Graft (Orca Q) for Pediatric Hematopoietic Cell Transplant (HCT) | NCT05322850 | Acute Myeloid L... Acute Lymphoid ... Mixed Phenotype... Acute Undiffere... Chronic Myeloid... Chronic Myeloid... Chronic Myeloid... | Orca-Q | - 50 Years | University of Florida | |
Vaccine Responses to Influenza A H1N1/09 Immunization in High-risk Patients | NCT01022905 | HIV Infection Rheumatic Disea... Cancer Transplant Pediatrics | Adjuvanted infl... | 6 Months - | University Hospital, Geneva | |
Pilot Study Combining Temozolomide, Oncovin, Camptosar and Oral Antibiotic in Children and Adolescents With Recurrent Malignancy | NCT00222443 | Lymphomas Tumors | Irinotecan | 1 Year - 21 Years | University of Oklahoma | |
Comparative Evaluation of MRI and MDCT for the Detection of Metastic Pulmonary Nodules | NCT00751920 | Metastatic Pulm... | Enhanced MRI Sc... | 2 Years - 18 Years | The Hospital for Sick Children | |
Collaborative Assessment of Pediatric Transverse Myelitis: Understand, Reveal, Educate or CAPTURE Study | NCT02144935 | Myelitis, Trans... Flaccid Paraple... Flaccid Paraple... | - 17 Years | University of Texas Southwestern Medical Center | ||
International Chronic Myeloid Leukemia Pediatric Study | NCT01281735 | Chronic Myeloid... | - 18 Years | Poitiers University Hospital | ||
Sirolimus in Combination With Metronomic Chemotherapy in Children With Recurrent and/or Refractory Solid and CNS Tumors | NCT02574728 | Cancer | Sirolimus Celecoxib Etoposide Cyclophosphamid... | 12 Months - 30 Years | Emory University | |
Taurolidine Lock Solution in the Prevention of Catheter Related Bacteremia | NCT00735813 | Bacteremia Neoplasms | Taurolock Heparin | - 17 Years | Aarhus University Hospital | |
Safety and Feasibility of Intraoperative Visualization With Cytalux in Children | NCT06235125 | Osteosarcoma Pulmonary Metas... Fluorescence Metastatic Sarc... Pediatrics | Cytalux | 6 Years - 17 Years | Ann & Robert H Lurie Children's Hospital of Chicago | |
To Evaluate the Safety, Activity and Pharmacokinetics of Marqibo in Children and Adolescents With Refractory Cancer | NCT01222780 | Sarcoma Neuroblastoma Wilms Tumor Leukemia Lymphoma Brain Tumors | Marqibo | 2 Years - 20 Years | Acrotech Biopharma Inc. | |
Pediatric Long-Term Follow-up and Rollover Study | NCT03975829 | Diffuse Astrocy... Anaplastic Astr... Astrocytoma Oligodendroglio... Anaplastic Olig... Glioblastoma Pilocytic Astro... Giant Cell Astr... Pleomorphic Xan... Anaplastic Pleo... Angiocentric Gl... Chordoid Glioma... Gangliocytoma Ganglioglioma Anaplastic Gang... Dysplastic Gang... Desmoplastic In... Papillary Glion... Rosette-forming... Central Neurocy... Extraventricula... Cerebellar Lipo... Neurofibromatos... | dabrafenib trametinib | 1 Year - | Novartis | |
Real World Evidence on the Use of Medical Cannabis in Pediatrics | NCT05863910 | Cancer Epilepsy Neurodevelopmen... | Medical Cannabi... | 3 Years - 17 Years | University of Manitoba | |
HSV G207 Alone or With a Single Radiation Dose in Children With Progressive or Recurrent Supratentorial Brain Tumors | NCT02457845 | Supratentorial ... Malignant Gliom... Glioblastoma Anaplastic Astr... PNET Cerebral Primit... Embryonal Tumor | G207 | 3 Years - 18 Years | University of Alabama at Birmingham | |
Cancer Predisposition Testing by Family-based Whole-genome Sequencing (WGS) in Every Child With Newly Diagnosed Cancer | NCT04903782 | Neoplastic Synd... Cancer Genetic Predisp... | Family-based wh... | - 21 Years | Sydney Children's Hospitals Network |